CN101829270A - Traditional Chinese medicine preparation for treating chronic renal failure and preparation method - Google Patents
Traditional Chinese medicine preparation for treating chronic renal failure and preparation method Download PDFInfo
- Publication number
- CN101829270A CN101829270A CN 201010178134 CN201010178134A CN101829270A CN 101829270 A CN101829270 A CN 101829270A CN 201010178134 CN201010178134 CN 201010178134 CN 201010178134 A CN201010178134 A CN 201010178134A CN 101829270 A CN101829270 A CN 101829270A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine preparation
- preparation
- chronic kidney
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine preparation for treating chronic renal failure and a preparation method. The invention aims to provide a traditional Chinese medicine preparation for treating chronic renal failure, which has obvious therapeutic effect, low cost, safety and reliability, good tolerance and high patient compliance. The traditional Chinese medicine preparation for treating chronic renal failure is prepared from raw materials comprising Astragalus mongholicus, epimedium herb, agilawood powder, roots of red-rooted salvia, prepared rhubarbs, red flowers and prepared sealwort. The traditional Chinese medicine preparation can regulate the metabolism functions of organisms, increase the exhaustion of the organisms for pathological products and reduce the retention of organic matter in bodies through the functions of replenishing vital essence, warming yang and eliminating turbid matter, thereby having the functions of protecting the organisms and strengthening kidney compensation. Compared with a method for treating by singly using Western medicine, the traditional Chinese medicine preparation has the characteristics of safe use, obvious effect of improving renal functions and promotion of toxin discharge and has an obvious function on delaying renal failures.
Description
Technical field
The present invention relates to the medicine of a kind of clinical medicine treatment chronic renal failure (abbreviation chronic kidney hypofunction), particularly a kind of Chinese medicine preparation and preparation method for the treatment of chronic kidney hypofunction.
Background technology
Chronic renal failure is meant a kind of clinical syndrome that occurs in the various chronic renal disease later stages, and going down with renal function is the retention of metabolite and poisonous substance, and Water-Electrolyte, acid base imbalance and some endocrine function are main performance unusually.
At present, the method for treatment chronic kidney hypofunction mainly adopts dialysis therapy and kidney transplantation, but has a series of problem in the actual therapeutic process: as the non-physiologic of dialysis therapy, and the transplanting matching method imperfection of renal transplantation, kidney source deficiency etc.; And the treatment cost is extremely expensive, and patient's acceptance level is poor.These factors have hindered above-mentioned Therapeutic Method applying in society.
Summary of the invention
The Chinese medicine preparation that the purpose of this invention is to provide a kind of evident in efficacy, cheap, safe and reliable, better tolerance, treatment chronic kidney hypofunction that patient's compliance is high.
The technical solution adopted in the present invention is finished in the following way: a kind of Chinese medicine preparation for the treatment of chronic kidney hypofunction, the raw material of the Chinese medicine preparation of this treatment chronic kidney hypofunction comprises the Radix Astragali, Herba Epimedii, Lignum Aquilariae Resinatum powder, Radix Salviae Miltiorrhizae, Radix et Rhizoma Rhei (processed), Flos Carthami and Rhizoma Polygonati (processed), and the weight proportion of the Chinese medicine preparation raw material of treatment chronic kidney hypofunction is: 30 parts of the Radixs Astragali, 10～30 parts of Herba Epimedii, 1～3 part in Lignum Aquilariae Resinatum powder, 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix et Rhizoma Rhei (processed), 5～15 parts on Flos Carthami, 15～25 parts of Rhizoma Polygonati (processed).
The concrete steps of the preparation method of the Chinese medicine preparation of treatment chronic kidney hypofunction of the present invention are:
(1) raw material that will treat the Chinese medicine preparation of chronic kidney hypofunction weighs up the clear water that the back adds 5～10 times by weight ratio, soaks in water 60～120 minutes;
(2) will mix the raw material and the water of the Chinese medicine preparation after soaking, adopt 80～120 ℃ of temperature, decoct 30～60 minutes;
(3) will obtain medicinal residues through step (2) after-filtration, and add 3～8 times clear water, it is fried to carry out secondary, and decocting time is 10～20 minutes;
(4) medicinal residues that will obtain through step (3) after-filtration add 3～5 times clear water, carry out three times fried, the fried time is 5～15 minutes;
(5) water preparation that step (2), (3) and (4) is obtained mixes;
(6) will concentrate through the water preparation that step (5) obtain, cocnentration factor is 5: 1～2.
Using method with the Chinese medicine preparation of treatment chronic kidney hypofunction of the present invention is: adult every day is oral twice, each 100ml, and two months is a course of treatment.
The present invention is based on the traditional Chinese medical science to pathogenetic understanding of chronic kidney hypofunction and Therapeutic Principle, discovers with reference to modern medicines, has selected to contain the Chinese herb medicine of various effective ingredient.Chinese medicine by benefit essence, warming YANG, let out turbid effect, can regulate the metabolic function of body, increase the discharge of body to pathological product, reduce organic retention in the body, thereby play the protection body, the compensatory effect of enhancing kidney.
Find through clinical comparison: after adopting Chinese medicine preparation of the present invention to treat a course of treatment, compare after a course of treatment with matched group (employing is taken Western medicine and liked the Seat sheet) treatment, the total effective rate that the group that adopts Chinese medicine preparation of the present invention to treat is treated chronic kidney hypofunction is 89.5%, matched group is 69.0% to the total effective rate of chronic kidney hypofunction treatment, and the total effective rate of treatment group is apparently higher than matched group (P＜0.05).
The present invention compares with simple use western medicine, has following characteristics:
1, the present invention selects for use natural plants, biology etc. to be raw material, and is safe in utilization, utilizes the comprehensive function treatment chronic kidney hypofunction of eight kinds of medicines, no obvious toxic and side effects.
2, the present invention has more and improves renal function, promotes the effect that toxin is discharged.Bring into play the Chinese medicine temperature male wind-supplying kidney, rushed down the characteristics of poison by becoming silted up, delayed on the renal failure effect significantly.
The specific embodiment
Below by embodiment the present invention is made further and to specify, but the invention is not restricted to these embodiment.
Embodiment 1
A kind of Chinese medicine preparation for the treatment of chronic kidney hypofunction, it is that Chinese herbal medicine by the following weight proportioning is the Chinese medicine preparation that raw material is made, Radix Astragali 30g wherein, Herba Epimedii 30g, Lignum Aquilariae Resinatum powder 1g, Radix Salviae Miltiorrhizae 10g, Radix et Rhizoma Rhei (processed) 15g, Flos Carthami 15g, Rhizoma Polygonati (processed) 20g.
The clear water of 10 times of above-mentioned medical material addings is fried jointly, fried 60 minutes; It is fried that the clear water that the medicinal residues adding that afterwards filtration is obtained is 5 times carries out secondary, fried 10 minutes; The medicinal residues that again filtration obtained add 4 times clear water carry out three times fried, fried 10 minutes; At last that first three time is the fried water preparation that obtains is concentrated into 100ml after mixing.
Embodiment 2
A kind of Chinese medicine preparation for the treatment of chronic kidney hypofunction, it is that Chinese herbal medicine by the following weight proportioning is the Chinese medicine preparation that raw material is made, Radix Astragali 30g wherein, Herba Epimedii 20g, Lignum Aquilariae Resinatum powder 3g, Radix Salviae Miltiorrhizae 15g, Radix et Rhizoma Rhei (processed) 20g, Flos Carthami 5g, Rhizoma Polygonati (processed) 25g.
The clear water of 8 times of above-mentioned medical material addings is fried jointly, fried 45 minutes; It is fried that the clear water that the medicinal residues adding that afterwards filtration is obtained is 3 times carries out secondary, fried 15 minutes; The medicinal residues that again filtration obtained add 5 times clear water carry out three times fried, fried 15 minutes; At last that first three time is the fried water preparation that obtains is concentrated into 100ml after mixing.
Embodiment 3
A kind of Chinese medicine preparation for the treatment of chronic kidney hypofunction, it is that Chinese herbal medicine by the following weight proportioning is the Chinese medicine preparation that raw material is made, Radix Astragali 30g wherein, Herba Epimedii 10g, Lignum Aquilariae Resinatum powder 2g, Radix Salviae Miltiorrhizae 20g, Radix et Rhizoma Rhei (processed) 10g, Flos Carthami 9g, Rhizoma Polygonati (processed) 15g.
The clear water of 5 times of above-mentioned medical material addings is fried jointly, fried 30 minutes; It is fried that the clear water that the medicinal residues adding that afterwards filtration is obtained is 8 times carries out secondary, fried 20 minutes; The medicinal residues that again filtration obtained add 3 times clear water carry out three times fried, fried 5 minutes; At last that first three time is the fried water preparation that obtains is concentrated into 100ml after mixing.
Reference examples
For the therapeutic effect of check the present invention to chronic kidney hypofunction, the present invention is carried out following clinical trial, its clinical experiment report is as follows:
1, case is selected
Selection meets chronic kidney hypofunction diagnostic criteria (case 112 examples of serum creatinine 177～707mmol/L).Patient is divided into two groups at random, and 57 examples are organized in treatment, wherein male 30 examples, women 27 examples; 24～79 years old age, average 51.8 years old; The course of disease 5～18 months, average 11.5 months.Matched group 55 examples, wherein male 28 examples, women 27 examples; 27～78 years old age, average 52.3 years old; The course of disease 4～17 months, average 10.8 months.Two groups of qualifications and record of service basically identicals, there was no significant difference has comparability.
2, Therapeutic Method
Treatment group patient takes Chinese medicine preparation of the present invention, and the adult is oral twice every day, each 100ml, and two months is a course of treatment.
Matched group is taken Western medicine and is liked the Seat sheet, oral three times of adult every day, and each 1.2g, two months is a course of treatment.
3, criterion
Produce effects: serum creatinine descends more than 30%, and subjective symptoms is improved, and cardinal symptom disappears;
Effectively: serum creatinine descends 15%～30%, and clinical symptoms is obviously improved;
Improve: serum creatinine descends below 15%, and clinical symptoms is improved;
Invalid: serum creatinine and clinical symptoms do not have improvement or increase the weight of.
4, result
Take in the treatment group of the present invention, produce effects 25 examples, effective 19 examples are improved 7 examples, invalid 6 examples, total effective rate 89.5%.
Produce effects 18 examples in the matched group, effective 12 examples are improved 8 examples, invalid 17 examples, total effective rate 69.0%.
The total effective rate of treatment group is apparently higher than matched group (P＜0.05).
Claims (3)
1. Chinese medicine preparation for the treatment of chronic kidney hypofunction, it is characterized in that: the raw material of the Chinese medicine preparation of this treatment chronic kidney hypofunction comprises the Radix Astragali, Herba Epimedii, Lignum Aquilariae Resinatum powder, Radix Salviae Miltiorrhizae, Radix et Rhizoma Rhei (processed), Flos Carthami and Rhizoma Polygonati (processed).
2. a kind of Chinese medicine preparation for the treatment of chronic kidney hypofunction according to claim 1 is characterized in that: the weight proportion of the Chinese medicine preparation raw material of treatment chronic kidney hypofunction is: 30 parts of the Radixs Astragali, 10～30 parts of Herba Epimedii, 1～3 part in Lignum Aquilariae Resinatum powder, 10～20 parts of Radix Salviae Miltiorrhizaes, 10～20 parts of Radix et Rhizoma Rhei (processed), 5～15 parts on Flos Carthami, 15～25 parts of Rhizoma Polygonati (processed).
3. a kind of preparation method for the treatment of the Chinese medicine preparation of chronic kidney hypofunction according to claim 1 and 2 is characterized in that: the concrete steps of the preparation method of the Chinese medicine preparation of treatment chronic kidney hypofunction are:
(1) raw material that will treat the Chinese medicine preparation of chronic kidney hypofunction weighs up the clear water that the back adds 5～10 times by weight ratio, soaks in water 60～120 minutes
(2) will mix the raw material and the water of the Chinese medicine preparation after soaking, adopt 80～120 ℃ of temperature, decoct 30～60 minutes;
(3) will obtain medicinal residues through step (2) after-filtration, and add 3～8 times clear water, it is fried to carry out secondary, and decocting time is 10～20 minutes;
(4) medicinal residues that will obtain through step (3) after-filtration add 3～5 times clear water, carry out three times fried, the fried time is 5～15 minutes;
(5) water preparation that step (2), (3) and (4) is obtained mixes;
(6) will concentrate through the water preparation that step (5) obtain, cocnentration factor is 5: 1～2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101781344A CN101829270B (en) | 2010-05-20 | 2010-05-20 | Traditional Chinese medicine preparation for treating chronic renal failure and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101781344A CN101829270B (en) | 2010-05-20 | 2010-05-20 | Traditional Chinese medicine preparation for treating chronic renal failure and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101829270A true CN101829270A (en) | 2010-09-15 |
| CN101829270B CN101829270B (en) | 2012-05-30 |
Family
ID=42713592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010101781344A Expired - Fee Related CN101829270B (en) | 2010-05-20 | 2010-05-20 | Traditional Chinese medicine preparation for treating chronic renal failure and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101829270B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102475765A (en) * | 2011-12-27 | 2012-05-30 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for improving renal functions and restraining renal fibrosis |
| CN103083413A (en) * | 2012-12-06 | 2013-05-08 | 宁夏易欣回药科技有限公司 | Traditional Chinese medicine composition patch for detoxifying and protecting kidney |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1385175A (en) * | 2001-05-11 | 2002-12-18 | 黎陆明 | Medicine for treating dermatomyositis |
-
2010
- 2010-05-20 CN CN2010101781344A patent/CN101829270B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1385175A (en) * | 2001-05-11 | 2002-12-18 | 黎陆明 | Medicine for treating dermatomyositis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102475765A (en) * | 2011-12-27 | 2012-05-30 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for improving renal functions and restraining renal fibrosis |
| CN102475765B (en) * | 2011-12-27 | 2014-01-01 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for improving renal functions and restraining renal fibrosis |
| CN103083413A (en) * | 2012-12-06 | 2013-05-08 | 宁夏易欣回药科技有限公司 | Traditional Chinese medicine composition patch for detoxifying and protecting kidney |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101829270B (en) | 2012-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102188560A (en) | Traditional Chinese medicine for treating hyperlipidemia | |
| CN102000262A (en) | Body-building traditional Chinese medicine for conditioning spleen-kidney yang deficiency sub-health | |
| CN102258710A (en) | Traditional Chinese medicine composition for treating type II diabetes | |
| CN102579755A (en) | Chinese medicinal formula for treating chronic renal failure | |
| CN102727815A (en) | Oral liquid for checking diarrhea and strengthening stomach | |
| CN101829270B (en) | Traditional Chinese medicine preparation for treating chronic renal failure and preparation method | |
| CN102429977B (en) | Medicine for treating diabetes | |
| CN103893457A (en) | Traditional Chinese medicine for treating ulcerative colitis | |
| CN102988650A (en) | Medicament for treating chronic nephritis and preparation method of medicament | |
| CN103272159A (en) | Chinese herbal preparation used for treating consumptive disease and preparation method thereof | |
| CN102961526A (en) | Compound proplis composition for treating urate deposition syndrome of broiler chicken and preparation method thereof | |
| CN102451458A (en) | Traditional Chinese medicine formula for treating chronic pyelonephritis | |
| CN101559113B (en) | Chinese materia medica preparation for treating chronic renal insufficiency and preparation method thereof | |
| CN1267124C (en) | Donky-hide blood-supplementing tonic and its preparation method | |
| CN103830415A (en) | Granule used for treatment of diabetes and preparation method thereof | |
| CN102366609B (en) | Body-building Chinese herbal medicine preparation for foot massage | |
| CN103417920A (en) | Traditional Chinese medicine formula for treating interstitial pneumonia | |
| CN102824461A (en) | Medicine for treating hypertension and preparation method thereof | |
| CN102872289B (en) | Traditional Chinese medicine composite for treating chronic gastritis and preparation method thereof | |
| CN101940773A (en) | Chinese medicinal herb for treating chronic bronchitis | |
| CN101385838B (en) | Kidney invigoration and sperm production preparation for treating oligospermatism and preparation method thereof | |
| CN101264208A (en) | Medicinal composition for treating stomach and intestine dysfunction and preparation thereof | |
| CN100475262C (en) | Liver-soothing and qi-dispersing medicine for preventing and treating SARS and viral hepatitis complication | |
| CN1298364C (en) | Medicine for treating pelvic inflammatory disease and its preparation process | |
| CN105521150A (en) | Preparation method traditional Chinese medicine for reducing blood fat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120530 |