CN101812130B - 人源抗狂犬病毒糖蛋白中和性抗体(RVFab5) - Google Patents
人源抗狂犬病毒糖蛋白中和性抗体(RVFab5) Download PDFInfo
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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| CN2010101708565A CN101812130B (zh) | 2010-05-06 | 2010-05-06 | 人源抗狂犬病毒糖蛋白中和性抗体(RVFab5) |
| PCT/CN2010/001576 WO2011137571A1 (fr) | 2010-05-06 | 2010-10-09 | Anticorps rvfab5 neutralisant d'origine humaine contre la glycoprotéine du virus de la rage |
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| CN2010101708565A CN101812130B (zh) | 2010-05-06 | 2010-05-06 | 人源抗狂犬病毒糖蛋白中和性抗体(RVFab5) |
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| CN101812130B (zh) * | 2010-05-06 | 2012-07-04 | 中国疾病预防控制中心病毒病预防控制所 | 人源抗狂犬病毒糖蛋白中和性抗体(RVFab5) |
| CN103998059B (zh) * | 2011-09-30 | 2016-01-20 | 赛特瑞恩股份有限公司 | 用于中和狂犬病病毒的结合分子 |
| EP3508497A1 (fr) | 2012-05-24 | 2019-07-10 | Mountgate Group Limited | Compositions et procédés associés à la prévention et au traitement d'une infection rabique |
| CN103505729B (zh) * | 2013-05-24 | 2015-10-28 | 华北制药集团新药研究开发有限责任公司 | 一种稳定的狂犬病毒人源抗体组合制剂 |
| CN113185608B (zh) * | 2021-05-08 | 2022-08-09 | 南昌大学 | 一种高亲和力抗狂犬病病毒的全人源单克隆抗体及其用途 |
| CN113501873B (zh) * | 2021-07-07 | 2023-05-23 | 高光 | Rbv的蛋白结合分子及其用途 |
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| CN101550189A (zh) * | 2008-04-25 | 2009-10-07 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | 人源抗狂犬病毒糖蛋白中和性基因工程抗体rd9及其制备与应用 |
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| CN101550189A (zh) * | 2008-04-25 | 2009-10-07 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | 人源抗狂犬病毒糖蛋白中和性基因工程抗体rd9及其制备与应用 |
Non-Patent Citations (2)
| Title |
|---|
| HOUIMEI M等.Isolation and characterization of human neutralizing antibodies to rabies virus derived from a recombinant immune antibody library.《Journal of Virological Methods》.2009,第161卷(第2期),第206-215页. * |
| KRAMER RA等.The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries.《European Journal of Immunology》.2005,第35卷(第7期),第2131-2145页. * |
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| CN101812130A (zh) | 2010-08-25 |
| WO2011137571A1 (fr) | 2011-11-10 |
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