CN101810870B - Method and device for controlling precise measurement of hydrogen peroxide pulsation injecting liquid through pressure negative feedbacks - Google Patents
Method and device for controlling precise measurement of hydrogen peroxide pulsation injecting liquid through pressure negative feedbacks Download PDFInfo
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- CN101810870B CN101810870B CN2010101485459A CN201010148545A CN101810870B CN 101810870 B CN101810870 B CN 101810870B CN 2010101485459 A CN2010101485459 A CN 2010101485459A CN 201010148545 A CN201010148545 A CN 201010148545A CN 101810870 B CN101810870 B CN 101810870B
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Abstract
The invention relates to a method for controlling precise measurement of hydrogen sulfide pulsation injecting liquid through pressure degenerative feedbacks. The method comprises the steps of placing articles to be disinfected in a sterile chamber for disinfection; using a vacuum system to extract vacuum or inflate for the sterile chamber in which the articles to be disinfected are placed; using a plasma generating device to excite the generation of plasmas; using pressure variation signals obtained by a testing control system in the sterile chamber to control a hydrogen peroxide injecting system and determine the dosage of an injected hydrogen peroxide disinfectant, and the injected hydrogen peroxide is excited by the plasmas. Thus, the hydrogen peroxide medium in the plasmas is fully excited, too much or too little injection of the hydrogen peroxide is prevented and precise control of the dosage of the hydrogen sulfide is achieved.
Description
Technical field
The present invention relates to the sterilizing methods of plasma sterilizer, more specifically, relate to method and device through the accurate measurement of pressure negative feedback control hydrogen peroxide pulsation injecting liquid.
Background technology
Plasma is a kind of particular matter form of extensively being present in occurring in nature (gaseous state, liquid state, the 4th a kind of form outside solid-state), a kind of high-octane material aggregation attitude.That forms plasma not only has molecule and an atom, also has many charged particles, and the energy of its particle does not wait to several thousand eV from several eV approximately, thereby it has special physicochemical property, with the interaction of material in can produce many special physics and chemical effect.The plasma sterilization technology is the new physical sterilization technology that the Disinfection field occurs in recent years; Adopt the sterilization technology of hydrogen peroxide plasma as biocide; With existing conventional sterilization technology apparatus in comparison; Has significant advantage: for example; For suitable plastic cement, optical fiber, artificial intraocular lenses and optical glass material of disinfecting with high-temperature steam method and infrared method, be not suitable for metal with the microwave method processing, and places such as corner, slit that are difficult for reaching Disinfection Effect, the using plasma sterilization technology can reach well at low temperatures and disappear the bacterium sterilization treatment and can not cause damage to being processed article; With clinical hydrogen peroxide (H commonly used
2O
2) be medium; Form plasma and accomplish sterilization through the radio-frequency electromagnetic field excitation; The plasma sterilization mechanism of action that with the hydrogen peroxide is medium is: compositions such as a large amount of active oxygen ions that contain in the plasma, the free group of high energy; Very easily with antibacterial, mycete and spore, virus in protein and nucleic acid substances generation oxidation reaction and degeneration makes all kinds of microbial deaths; Plasma high speed particle breakdown effects; After the sterilization experiment; Through antibacterial thalline and the virion image of electron microscopic observation after action of plasma, all present riddled with gaping wounds shape, this is by due to the puncture etch effects of electronics with kinetic energy and ion generation; Action of ultraviolet ray is exciting H
2O
2Form in the process of plasma, be attended by the part ultraviolet and produce, this high energy ultraviolet photon is absorbed by protein in microorganism or the virus, causes its molecule degeneration inactivation.And the end product of plasma is quantities and oxygen, and the residual and discharge of non-poisonous material is harmless to the medical worker, environmentally safe.And sterilising temp is low, and sterilising cycle is short, and applied widely, easy and simple to handle, energy consumption is low.
The hydrogen peroxide injection mode of common plasma sterilizer has: capsule punctures injection mode, modes such as the atomizing injection mode of 2 heating, ultrasonic atomizatio injection mode, and aforesaid way can be realized the injection to the hydrogen peroxide of steriliser; But exist the dosage of hydrogen peroxide uncontrollable; Too small when the hydrogen peroxide medium dosage that adds, may cause sterilization not thorough, cause apparatus contamination, produce serious harm; And if the hydrogen peroxide medium that adds is excessive; Decompose incomplete words and make the sterilizing objects surface have residual peroxide, residual hydrogen peroxide can damage user, influences the health of user.Therefore, through the dosage of the hydrogen peroxide in the control injected plasma sterile chamber, realize that the hydrogen peroxide medium is excited fully, prevents H in plasma
2O
2Injecting too much perhaps very few situation is the problem that needs solution.
Summary of the invention
Be the purpose that realizes the dosage of hydrogen peroxide is accurately controlled; The present invention provides a kind of method and device through the accurate measurement of pressure negative feedback control hydrogen peroxide pulsation injecting liquid; Prevent that hydrogen peroxide from injecting too much or very few situation takes place, realize the dosage of hydrogen peroxide is accurately controlled.
For this purpose, scheme of the present invention provides a kind of method through the accurate measurement of pressure negative feedback control hydrogen peroxide pulsation injecting liquid, and this method comprises:
Article to be sterilized are positioned over the sterile chamber to carry out disinfection;
Utilize vacuum system that the sterile chamber that is placed with article to be sterilized is carried out extracting vacuum or inflation;
Utilize the plasma generating device in the sterile chamber to excite the generation plasma;
Utilize the pressure change signal in the sterile chamber of detecting the control system acquisition, control the hydrogen peroxide biocide dosage that hydrogen peroxide injected system and decision are injected, the hydrogen peroxide of said injection is excited by plasma.
Wherein, this method further comprises, writes down the related data of plasma sterilizer operation through recording system.
Wherein, The data of utilizing said detection control system collection vacuum measurement element and pressure transducer to record; Obtain the pressure change signal in the sterile chamber, this detections control system is controlled and adjusting hydrogen peroxide implantation dosage, temperature, electromagnetic valve are opened time, fluid injection total time, electromagnetic valve and opened number of times, injection pressure.
Wherein, hydrogen peroxide injects through the mode of pulsation, evenly injects with 20 times/second speed.
The present invention also provides a kind of device through the accurate measurement of pressure negative feedback control hydrogen peroxide pulsation injecting liquid; Comprise sterile chamber, vacuum system, plasma generating device and detect control system and hydrogen oxide injected system; Wherein, said excitation device has radio-frequency power supply, mesh-like antenna, through said radio-frequency power supply is applied on the mesh-like antenna with activated plasma; Wherein, this mesh-like antenna is arranged on the inner relative inwall in sterile chamber through insulating support.
Wherein, Said vacuum system comprises vacuum pump, filters aerator, gas tube, vacuum tube, second valve etc., and its intermediate pump carries out extracting vacuum through vacuum tube to the sterile chamber; Said second valve is controlled extracting vacuum; Filter aerator and gas tube the air pressure of sterile chamber is regulated, the gas that control charges into the sterile chamber carries out concora crush to vacuum chamber.
Wherein, said hydrogen peroxide injected system comprises fluid reservoir, first valve, electromagnetic valve, vaporization and metering device, and hydrogen peroxide is injected in the sterile chamber by pulsating through said hydrogen peroxide injected system, forms hydrogen peroxide plasma.
Thereby, realize that the hydrogen peroxide medium is excited fully in plasma, prevent that hydrogen peroxide from injecting too much or very few situation takes place, realize the dosage of hydrogen peroxide is accurately controlled.
Advantage of the present invention will combine in the accompanying drawing the detailed description of embodiment and more obvious through hereinafter.
Description of drawings
The cross section structure sketch map of Fig. 1 plasma sterilizer;
Fig. 2 steriliser workflow sketch map.
Reference numeral: 1. mesh-like antenna; 2. hydrogen peroxide liquid; 3. fluid reservoir; 4. vaporize and metering device; 5. insulating support; 6. heater; 7. temperature element; 8. sterile chamber; 9. vacuum measurement element; 10. recording system; 11. detection control system; 12. vacuum system; 13. valve B; 14. radio-frequency power supply; 15. dc source; 16. electromagnetic valve; 17. valve A.
The specific embodiment
Fig. 1 is the cross section structure sketch map of plasma sterilizer, through the description to the structure of steriliser, with operation principle and the concrete method for using that this steriliser is described.
The agent structure of this plasma steriliser is sterile chamber 8; This sterile chamber is column type or rectangular configuration; When using this plasma sterile chamber to sterilize; In article placement to be sterilized and sterile chamber 8,8 inner top and bottoms, sterile chamber are provided with the mesh-like antenna 1 that is used for activated plasma, and the connection mesh-like antenna that is positioned at the place, top is fixed in the sterile chamber 8 through insulating support 5; Wherein, this mesh-like antenna 1 also can be arranged on the relative inwall in 8 inside, sterile chamber through insulating support.Can produce plasma through on this mesh-like antenna 1, applying power supply, exciting.Sterile chamber 8 is connected with a plurality of parts such as radio-frequency power supply 14, dc source 15, detection control system 11, recording system 10, vacuum system 12, hydrogen peroxide injected systems.Sterile chamber 8 is formed for the plasma that excites the hydrogen peroxide medium to carry out disinfection through plasma generating device; Wherein, This plasma generator comprises mesh-like antenna, radio-frequency power supply, dc source, insulating support, sterile chamber's inwall etc.; Through applying radio-frequency power supply, the mesh-like antenna 1 that is arranged on sterile chamber's inwall excites the medium that is positioned at sterile chamber 8, produces plasma.
On the inwall of sterile chamber 8, be provided for measuring the temperature element 7 of this sterile chamber's internal temperature; This temperature element 7 can be that thermal detector, thermometer or thermocouple etc. can be realized device that temperature is detected; The outer wall of this sterile chamber is provided with heater 6, and this heater can be used for hydrogen peroxide is heated.In addition, on the inwall of this sterile chamber 8, further be provided with vacuum measurement element 9, this vacuum measurement element 9 is used to detect the vacuum in the sterile chamber, this vacuum measurement element 9 can be vacuometer, vacuum silicone tube or other vacuum measuring device.
The hydrogen peroxide injected system comprises fluid reservoir 3, valve A17, electromagnetic valve 16 and hydrogen peroxide vaporization and the measuring device 4 of storing hydrogen peroxide liquid 2; Wherein, this hydrogen peroxide vaporization and metering device 4 link to each other with sterile chamber 8, and the hydrogen peroxide liquid of from electromagnetic valve 16, passing through is vaporization in device 4; Because the air pressure in the sterile chamber 8 is little; The liquid of device in 4 is vaporized and evenly is diffused in the sterile chamber 8, and hydrogen peroxide is excited, and the plasma of generation is treated the sterilizing objects sterilization that carries out disinfection.Valve A is between fluid reservoir 3 and hydrogen peroxide vaporization and metering device 4.
Shown in Figure 2, be of the present invention through pressure negative feedback control hydrogen peroxide pulsation injecting liquid accurate measurement sketch map, at first; Can article to be sterilized be positioned over sterile chamber 8 to carry out disinfection, utilize vacuum system that the sterile chamber 8 that is placed with article to be sterilized is carried out extracting vacuum or inflation, wherein; Open valve B, valve-off A through detection, control system 11; Extract the air in the sterile chamber 8 out through vacuum system, be extracted into the vacuum condition of plasma discharge, when keeping pressure stable; The generator of plasma makes plasma begin discharge, forms plasma.
Secondly, through detecting control system 11 valve-off B, opening valve A, program enters into the fluid injection program, automatically the hydrogen peroxide biocide is injected into sterile chamber 8, through H
2O
2Vaporization and metering device 4, moment is vaporized into hydrogen peroxide gas with hydrogen peroxide liquid, and evenly is diffused into whole sterile chamber; Detect control system 11 and judge the state in the sterile chamber 8 according to the vacuum of vacuum measurement element survey and the sensing data of pressure transducer, calculating needs the dosage of the hydrogen peroxide of adding.
In the fluid injection program, detect control system 11 and control electromagnetic valves 16 and hydrogen peroxide vaporization and measuring device 4, control the time of electromagnetic valve 16 unlatchings or the dosage that the liquid of electromagnetic valve 16 is passed through in control according to the implantation dosage that calculates.Wherein, This hydrogen peroxide is by the heater heating, through the vaporization rapidly of vapourizing unit quilt, and this hydrogen peroxide vaporization and metering device 4 link to each other with sterile chamber 8, and hydrogen peroxide is through going into the sterile chamber; Monitored and the metering of whole process; Because the pressure negative feedback in the sterile chamber 8 makes the liquid in the device 4 be vaporized and evenly be diffused in the sterile chamber 8, hydrogen peroxide is excited, and the plasma of generation is treated the sterilizing objects sterilization that carries out disinfection.
Can control and regulate implantation dosage, temperature, electromagnetic valve in real time and open time, fluid injection total time, electromagnetic valve and open number of times, injection pressure through detecting control system 11; Recording system 10 can the real time record steriliser related data of operation; Electromagnetic valve 16 can also play the hydrogen peroxide gas backflow effect that prevents except that the dosage of the hydrogen peroxide that is used to control adding.
Detect the control system and based on pressure sensor and vacuum meter etc. the adding of hydrogen peroxide is controlled in the monitoring of inside, sterilizing chamber, wherein, this hydrogen peroxide injects through the mode of pulsing, and evenly injects with 20 times/second speed.The whole process that hydrogen peroxide injects is all carried out under the control that detects control system 11, and by 10 records of recording system, the dose accuracy of hydrogen peroxide is controlled at ± 0.001ml.
This plasma steriliser can be according to concrete sterilization requirement; Sterilizing objects is carried out multistep sterilizes suddenly; Guarantee the disinfectant effect; And in each sterilisation step, the dosage owing to accurately controlled the hydrogen peroxide that injects according to the pressure negative feedback in the sterile chamber has guaranteed disinfectant effectiveness and safety.
Although illustrate and described the present invention with reference to embodiments of the invention; But those skilled in the art should understand that; Specific embodiments of enumerating in this description or embodiment; Only in order to understand technology contents of the present invention, under the situation that does not deviate from purport of the present invention and scope, the present invention can carry out multiple change in form with on the details.
Claims (2)
1. one kind is passed through the method that the pressure negative feedback controls the accurate measurement of hydrogen peroxide pulsation injecting liquid, and this method comprises:
Article to be sterilized are positioned over the sterile chamber to carry out disinfection;
Utilize vacuum system that the sterile chamber that is placed with article to be sterilized is carried out extracting vacuum or inflation;
Utilize the plasma generating device in the sterile chamber to excite the generation plasma;
Utilize the pressure change signal in the sterile chamber of detecting the control system acquisition, control the hydrogen peroxide injected system, and the hydrogen peroxide biocide dosage of decision injection, the hydrogen peroxide of said injection is excited by plasma;
This method further comprises, writes down the related data of plasma sterilizer operation through recording system;
The data of utilizing said detection control system collection vacuum measurement element and pressure transducer to record; Obtain the pressure change signal in the sterile chamber, this detections control system is controlled and adjusting hydrogen peroxide implantation dosage, temperature, electromagnetic valve are opened time, fluid injection total time, electromagnetic valve and opened number of times, injection pressure;
Hydrogen peroxide injects through the mode of pulsation, evenly injects with 20 times/second speed.
2. one kind is passed through the device that the pressure negative feedback controls the accurate measurement of hydrogen peroxide pulsation injecting liquid; Comprise sterile chamber, vacuum system, plasma generating device and detect control system and hydrogen peroxide injected system; It is characterized in that: said plasma producing apparatus has radio-frequency power supply, mesh-like antenna; Through said radio-frequency power supply being applied on the mesh-like antenna with activated plasma, wherein, this mesh-like antenna is arranged on the inner relative inwall in sterile chamber through insulating support;
Said hydrogen peroxide injected system comprises fluid reservoir, first valve, electromagnetic valve, vaporization and metering device, and hydrogen peroxide is injected in the sterile chamber by pulsating through said hydrogen peroxide injected system, forms hydrogen peroxide plasma;
Said vacuum system; Comprise vacuum pump, filter aerator, gas tube, vacuum tube, second valve; Its intermediate pump carries out extracting vacuum through vacuum tube to the sterile chamber, and said second valve is controlled extracting vacuum, filters aerator and gas tube the air pressure of sterile chamber is regulated; The gas that control charges into the sterile chamber carries out concora crush to vacuum chamber.
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| CN2010101485459A CN101810870B (en) | 2010-04-16 | 2010-04-16 | Method and device for controlling precise measurement of hydrogen peroxide pulsation injecting liquid through pressure negative feedbacks |
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| CN2010101485459A CN101810870B (en) | 2010-04-16 | 2010-04-16 | Method and device for controlling precise measurement of hydrogen peroxide pulsation injecting liquid through pressure negative feedbacks |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103480019A (en) * | 2013-08-23 | 2014-01-01 | 苏州康华净化系统工程有限公司 | Ultraviolet ray disinfecting system |
| CN105311658A (en) * | 2014-07-31 | 2016-02-10 | 北京白象新技术有限公司 | Air disinfecting machine with cloud service function |
| CN105288682A (en) * | 2014-07-31 | 2016-02-03 | 北京白象新技术有限公司 | Washer-disinfector with cloud service function |
| CN105311657A (en) * | 2014-07-31 | 2016-02-10 | 北京白象新技术有限公司 | High-temperature high-pressure sterilizer with cloud service function |
| CN105311667A (en) * | 2014-07-31 | 2016-02-10 | 北京白象新技术有限公司 | Low-temperature plasma sterilizer with cloud service function |
| WO2018182929A1 (en) * | 2017-03-27 | 2018-10-04 | Regeneron Pharmaceuticals, Inc. | Sterilisation method |
| CN108686241B (en) * | 2017-04-10 | 2021-03-26 | 山东新华医疗器械股份有限公司 | Sterilization method and sterilization apparatus |
| CN113209343A (en) * | 2021-04-19 | 2021-08-06 | 杭州优尼克消毒设备有限公司 | Ethylene oxide sterilizer compatible with mixed gas |
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| CN200984336Y (en) * | 2006-12-15 | 2007-12-05 | 孟月东 | Hydrogen peroxide vacuum plasma body cold sterilization device |
| CN201018709Y (en) * | 2007-04-05 | 2008-02-06 | 北京白象新技术有限公司 | Plasma testing apparatus in low temperature plasma disinfection device |
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Patent Citations (4)
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| CN200984336Y (en) * | 2006-12-15 | 2007-12-05 | 孟月东 | Hydrogen peroxide vacuum plasma body cold sterilization device |
| CN201018709Y (en) * | 2007-04-05 | 2008-02-06 | 北京白象新技术有限公司 | Plasma testing apparatus in low temperature plasma disinfection device |
| CN201020056Y (en) * | 2007-04-05 | 2008-02-13 | 北京白象新技术有限公司 | AC DC hybrid starting low-temperature plasma sterilization device with self-checking function |
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Denomination of invention: Method and device for controlling precise measurement of hydrogen sulfide pulsation injecting liquid through pressure degenerative feedbacks Effective date of registration: 20130318 Granted publication date: 20120905 Pledgee: Industrial Commercial Bank of China Ltd Beijing Chaoyang sub branch Pledgor: Beijing Baixiang Science & Technology Co., Ltd. Registration number: 2013990000154 |
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