CN101803925B - Monitoring device of blood oxygen saturation in motion state - Google Patents
Monitoring device of blood oxygen saturation in motion state Download PDFInfo
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- CN101803925B CN101803925B CN2010101364492A CN201010136449A CN101803925B CN 101803925 B CN101803925 B CN 101803925B CN 2010101364492 A CN2010101364492 A CN 2010101364492A CN 201010136449 A CN201010136449 A CN 201010136449A CN 101803925 B CN101803925 B CN 101803925B
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Abstract
The invention relates to a monitoring device of blood oxygen saturation in motion state in the technical field of medical appliances, which comprises a PPG signal generation module, a motion signal generation module, a signal processing module, a communication module and a man-machine interaction module. Compared with a traditional blood oxygen saturation monitoring device, the device adds the motion signal generation module for monitoring the motion acceleration of a space: in a signal acquisition stage, the output information of the motion signal generation module is used for adjusting the amplification process of the PPG signal; and in a signal processing stage, the output information of the motion signal generation module is used for eliminating the motion noise in the PPG signal. The monitoring device of blood oxygen saturation in motion state can effectively eliminate the impact of the motion noise in the blood oxygen monitoring process, improve the monitoring accuracy, and enlarge the scope of use of the device.
Description
Technical field
What the present invention relates to is a kind of device of Medical Instruments technical field, specifically is blood oxygen saturation monitoring device based under a kind of kinestate.
Background technology
The needed oxygen of human body metabolism, be through with blood in hemoglobin (Hb) be combined into to be transported in the different tissues cell behind the HbO2 Oxyhemoglobin (HbO2) and go.Blood oxygen saturation (SaO2) has then represented in the blood to be accounted for by the bonded HbO2 Oxyhemoglobin of oxygen (HbO2) percentage ratio of whole combinative hemoglobin (Hb), the i.e. concentration of blood oxygen in the blood.Therefore monitor SaO2 to understanding respiratory system, blood circulation situation and prevention histanoxia etc. plays an important role.
At present; Existing oxygen saturation monitor device all is according to Lambert-beer principle and photoelectric technology; At first obtain the photoelectricity volume pulsation wave (photoplethysmography under HONGGUANG and the infrared light through photoelectric technology; PPG), relatively calculate two PPG signals based on Lambert beer principle afterwards and obtain oximetry value.This device technique is ripe, in operation, is widely used in the clinical monitoring.Yet these monitorings all need experimenter's state of keeping quite, and motion is the main reason that influences signal monitoring.
Find that through existing technology retrieval Chinese application number is: 200510121269.6, name is called: can eliminate the blood oxygen measuring method and the device thereof of motion artifacts, this technology provides the blood oxygen measuring device that can realize eliminating motion artifacts.This device comprises: blood oxygen probe head component, and signal processing and amplifying assembly, the A/D conversion, the single-chip data processing components, Logic control module and power circuit, wherein probe assembly comprises: HONGGUANG, infrared light supply, drive circuit and light-receiving tube; Signal processing and amplifying assembly comprises: differential amplifier circuit and signal processing circuit; Logic control and functional module comprise: security function and communication function; Single-chip data processing module assembly has comprised the motion artifacts module; The motion artifacts module comprises: pulse wave calculation of parameter, differential processing module, medium filtering module and area integral recurrence module.The outfan of this fortune merit interference module connects A/D conversion and logic control and functional module respectively.But should technology not comprise the device of monitoring experimenter's kinestate, and under the situation of not knowing experimenter's actual motion signal, relied on great amount of calculation to remove the motion noise, therefore the operand of device is excessive, and only effective to the tangible signal of Partial Feature.
Summary of the invention
The objective of the invention is to overcome the above-mentioned deficiency of prior art, blood oxygen saturation monitoring device based under a kind of kinestate is provided.The present invention is based on the motion monitoring signal of sensor and eliminate the motion noise, realize kinestate blood oxygen saturation monitoring down, it is accurate and volume is little, the advantage of light weight to have a monitoring.
The present invention realizes through following technical scheme:
The present invention includes: PPG signal generation module, motor message generation module, signal processing module, communication module and human-computer interaction module; Wherein: PPG signal generation module links to each other with signal processing module and transmits the PPG signal under HONGGUANG and the infrared light; The motor message generation module acceleration magnitude of transmission people soma on three the mutual vertical direction in space that link to each other with signal processing module; Communication module link to each other with signal processing module transmission blood oxygen signal and heart rate information, human-computer interaction module link to each other with signal processing module transmission of control signals and display result information.
Described PPG signal generation module comprises: an infrared diode, a near infrared diode and a photodiode; Wherein: infrared diode and near infrared diode reverse parallel connection; Infrared diode all links to each other with signal processing module with near infrared diode, and photodiode links to each other with signal processing module.
Described motor message generation module is an acceleration transducer.
Described signal processing module comprises: microprocessor, photoelectricity drive circuit, amplification filtering circuit, power circuit and memory device; Wherein: the photoelectricity drive circuit links to each other with PPG signal generation module and transmits the luminous current signal of control; The photoelectricity drive circuit links to each other with microprocessor to transmit and drives signal; The amplification filtering circuit links to each other with PPG signal generation module and transmits the PPG signal; Microprocessor links to each other with the amplification filtering circuit and transmits the amplification filtering signal; Microprocessor links to each other with the motor message generation module and transmits the acceleration signal of three directions, and microprocessor links to each other with memory device and transmits blood oxygen signal and heart rate information, and microprocessor links to each other with power circuit and transmits power information; Microprocessor link to each other with communication module transmission blood oxygen signal and heart rate information, microprocessor link to each other with human-computer interaction module transmission of control signals and display result information.
Described microprocessor is provided with analog-digital converter.
Described communication module comprises: wire communication submodule and radio communication submodule, wherein: the wire communication submodule all links to each other with signal processing module with the radio communication submodule and transmits blood oxygen and heart rate information.
Described wire communication submodule comprises: photoelectric isolating device and RS232 serial ports, and wherein: photoelectric isolating device links to each other with signal processing module and transmits blood oxygen and heart rate information, and photoelectric isolating device links to each other with the RS232 serial ports and transmits blood oxygen and heart rate information.
Described radio communication submodule is based on the less radio-frequency transmitter module of ZIGBEE agreement, its link to each other with signal processing module wireless transmission blood oxygen and heart rate signal.
Described human-computer interaction module comprises: button and lattice lcd, and wherein: button links to each other with signal processing module and transmits control information, and lattice lcd links to each other with signal processing module and shows blood oxygen and heart rate result.
Work process of the present invention is: the conducting of microprocessor control photoelectricity drive circuit generates the anti-phase amplified current; Two light emitting diodes are alternately luminous under the effect of negative-phase sequence curent; Photodiode receives the light of penetrate tissue, gives filter amplification circuit with current delivery; Filter amplification circuit is passed to microcontroller with pretreated PPG analogue signal; Microprocessor receives the PPG analogue signal and is converted into digital signal, carries out the PPG Digital Signal Processing; Microprocessor receives the acceleration signal of motor message generation module, and carries out acceleration signal and handle; Microprocessor recovers the PPG signal that the passive movement noise floods based on acceleration signal, and calculates blood oxygen and heart rate result; Microprocessor sends to wire communication module with result, and sends to host computer through the RS232 serial ports; Microprocessor sends to result wireless communication module and then is transferred to other receiving system; Microprocessor sends to display module with the result, shows real-time blood oxygen and heart rate through lattice lcd.Button links to each other with microprocessor and supplies user selective system mode of operation.
Compared with prior art; The invention has the beneficial effects as follows: can effectively suppress the motion noise; Realize that the blood oxygen signal under the non-peculair motion state monitors in real time: utilize acceleration sensor chip to generate motor message; Quantize unknown originally motion noise, thereby effectively controlled the collection of PPG analogue signal and the noise reduction process of PPG digital signal, thereby realized kinestate hematochezia oxygen information monitoring; In addition, the wireless transmission that the present invention is based on the ZIGBEE agreement can realize monitoring blood oxygen, the high speed of heart rate information, the transmitted in both directions of low-power consumption.Therefore the present invention not only can improve the accuracy of oxygen saturation monitor, is equally applicable to the monitoring of kinestate hematochezia oxygen signal, enlarges the scope of application of such device, but also it is little to have a volume, and characteristics such as light weight have realized the conversion of real-time dynamic monitoring blood oxygen.
Description of drawings
Fig. 1 is a composition sketch map of the present invention.
The specific embodiment
Elaborate in the face of embodiments of the invention down, present embodiment provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment being to implement under the prerequisite with technical scheme of the present invention.
Embodiment
As shown in Figure 1; Present embodiment comprises: PPG signal generation module, motor message generation module, signal processing module, communication module and human-computer interaction module; Wherein: PPG signal generation module links to each other with signal processing module and transmits the PPG signal under HONGGUANG and the infrared light; The motor message generation module is through the SPI mouth acceleration magnitude of transmission people soma on three the mutual vertical direction in space that link to each other with signal processing module; Communication module links to each other with signal processing module and transmits blood oxygen information and heart rate information, and human-computer interaction module links to each other with signal processing module and transmits control information and monitoring result.
Described PPG signal generation module comprises: 840mn light emitting diode, 960mn light emitting diode and photodiode; Wherein: 840mn light emitting diode and 960mn light emitting diode reverse parallel connection; The 840mn light emitting diode links to each other with signal processing module; The 960mn light emitting diode links to each other with signal processing module, and 840mn light emitting diode and 960mn light emitting diode are alternately luminous, and photodiode links to each other with signal processing module and transmits the current signal that comprises blood oxygen information.
Described motor message generation module is an acceleration transducer, and the model of the acceleration transducer that present embodiment adopts is MMA7260QT, its transmission X that links to each other with signal processing module, Y, three axial acceleration of motion information of Z.
Described signal processing module comprises: microprocessor, photoelectricity drive circuit, amplification filtering circuit, power circuit and storage card; Wherein: the photoelectricity drive circuit links to each other with PPG signal generation module and transmits the luminous current signal of control; The photoelectricity drive circuit links to each other with microprocessor; The amplification filtering circuit links to each other with PPG signal generation module and transmits the PPG signal, and microprocessor links to each other with the amplification filtering circuit, and microprocessor links to each other with the motor message generation module and transmits the acceleration signal of three directions; Microprocessor links to each other with storage card and transmits blood oxygen signal and heart rate information; The microprocessor transmission power information that links to each other with power circuit, microprocessor links to each other with communication module and transmits blood oxygen signal and heart rate information, microprocessor link to each other with human-computer interaction module transmission of control signals and display result information.
Microprocessor described in the present embodiment is the super low-power consumption microprocessor MSP430FG439 of American TI Company; It is built-in with analog-digital converter, and this chip is little except volume, low in energy consumption outside; Chip contains abundant external resource; Present embodiment uses two operational amplifier 0A wherein, 12 analog digital conversion ADC, two intervalometer TIMER etc.Not only simplify circuit design based on resource in the sheet of this microprocessor, dwindle the circuit volume, and avoid external electromagnetic interference, improve systematic function.
Described communication module comprises: wire communication submodule and radio communication submodule, wherein: the wire communication submodule all links to each other with signal processing module with the radio communication submodule and transmits blood oxygen and heart rate information.
Described wire communication submodule comprises: photoelectric isolating device and RS232 serial ports, and wherein: photoelectric isolating device links to each other with signal processing module and transmits blood oxygen and heart rate information, and photoelectric isolating device links to each other with the RS232 serial ports and transmits blood oxygen and heart rate information.
Described radio communication submodule is based on the less radio-frequency transmitter module of ZIGBEE agreement, its link to each other with signal processing module wireless transmission blood oxygen and heart rate signal, and present embodiment is selected the low-power consumption chip CC2500 of American TI Company for use.
Described human-computer interaction module comprises: the lattice lcd of button and 128*64, and wherein: button links to each other with signal processing module and transmits control information, and lattice lcd links to each other with signal processing module and shows blood oxygen and heart rate result.
The work process of present embodiment is:
1, startup self-detection: after system powers on, accomplish the initialization to microprocessor automatically, system's operate as normal is guaranteed in the initialization of acceleration chip, and the inspection of other module operate as normal.
2, the generation of PPG signal: under the control of microprocessor, PPG signal generation module generates the PPG signal, and the motor message generation module generates the acceleration magnitude of transmission people soma on three the mutual vertical direction in space.
3, the amplification filtering of PPG signal: under moving situation; The situation such as seriously overflowing range to such an extent as to useful signal possibly flooded by excessive motor message or drift about; Present embodiment is corrected primary signal with the motor message of monitoring and is amplified; The PPG signal is effectively amplified, and motor message is suppressed, and the signal after the amplification is removed other frequency content through filtering.
4, the analog digital conversion of PPG signal:, be that digital signal is used for follow-up Digital Signal Processing with analog signal conversion through the built-in analog-digital converter of microprocessor.
5, burbling noise: the PPG signal is amplifying through overcorrection; Still contain the eclipsed noise signal of part time-domain frequency-domain characteristic after the filtering; Present embodiment is further isolated noise through the method for adaptive-filtering based on PPG and acceleration signal, obtains ideal PPG signal.
6, data storage: system is saved to the PPG signal on the built-in storage card.
7, physiological parameter shows and transmission: based on acceleration and PPG signal, system can obtain the gait about monitoring person, and parameters such as heart rate and blood oxygen saturation show monitoring result through lattice lcd, and transmit through communication module.
The advantage of present embodiment is: the MMA7260QT acceleration sensor chip can be expressed as space motion the size of three mutual vertical direction acceleration, and shows with correspondent voltage value size, passes to microprocessor through the SPI mode.Microprocessor can be adjusted the amplification process of PPG signal based on these signals, and removes the motion noise in the PPG signal through the method for adaptive-filtering; Adopted super low-power consumption microprocessor MSP430FG439, every 1MHz under the CPU mode of operation, electric current are 300 μ A, minimum current 0.1 μ A under the CPU sleep pattern.In addition, the peripheral hardware that enriches that system contains is promptly simplified circuit design, and the reduction system volume has been avoided extraneous electromagnetic interference again, improves systematic function; The low-consumption wireless radio-frequency transmissions chip CC2500 that system adopts can transmit data efficiently based on the ZIGBEE agreement.
Claims (1)
1. blood oxygen saturation monitoring device based under the kinestate; Comprise: PPG signal generation module, signal processing module, communication module and human-computer interaction module; It is characterized in that; Also comprise: motor message generation module, the motor message generation module acceleration magnitude of transmission people soma on three the mutual vertical direction in space that link to each other with signal processing module, the PPG signal generation module PPG signal under transmission HONGGUANG and the infrared light that links to each other with signal processing module; Communication module link to each other with signal processing module transmission blood oxygen signal and heart rate information, human-computer interaction module link to each other with signal processing module transmission of control signals and display result information;
Described motor message generation module is an acceleration transducer;
Described PPG signal generation module comprises: an infrared diode, a near infrared diode and a photodiode; Wherein: infrared diode and near infrared diode reverse parallel connection; Infrared diode all links to each other with signal processing module with near infrared diode, and photodiode links to each other with signal processing module;
Described signal processing module comprises: microprocessor, photoelectricity drive circuit, amplification filtering circuit, power circuit and memory device; Wherein: the photoelectricity drive circuit links to each other with PPG signal generation module and transmits the luminous current signal of control; The photoelectricity drive circuit links to each other with microprocessor to transmit and drives signal; The amplification filtering circuit links to each other with PPG signal generation module and transmits the PPG signal; Microprocessor links to each other with the amplification filtering circuit and transmits the amplification filtering signal; Microprocessor links to each other with the motor message generation module and transmits the acceleration signal of three directions, and microprocessor links to each other with memory device and transmits blood oxygen signal and heart rate information, and microprocessor links to each other with power circuit and transmits power information; Microprocessor link to each other with communication module transmission blood oxygen signal and heart rate information, microprocessor link to each other with human-computer interaction module transmission of control signals and display result information;
Described microprocessor is provided with analog-digital converter;
Described communication module comprises: wire communication submodule and radio communication submodule, and wherein: the wire communication submodule all links to each other with signal processing module with the radio communication submodule and transmits blood oxygen and heart rate information;
Described wire communication submodule comprises: photoelectric isolating device and RS232 serial ports, and wherein: photoelectric isolating device links to each other with signal processing module and transmits blood oxygen and heart rate information, and photoelectric isolating device links to each other with the RS232 serial ports and transmits blood oxygen and heart rate information;
Described radio communication submodule is based on the less radio-frequency transmitter module of ZIGBEE agreement, its link to each other with signal processing module wireless transmission blood oxygen and heart rate signal;
Described human-computer interaction module comprises: button and lattice lcd, and wherein: button links to each other with signal processing module and transmits control information, and lattice lcd links to each other with signal processing module and shows blood oxygen and heart rate result.
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