CN101801391B - 透明质酸在制备用于改善皮肤、眼和粘膜的保护功能的组合物中的用途 - Google Patents

透明质酸在制备用于改善皮肤、眼和粘膜的保护功能的组合物中的用途 Download PDF

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Publication number
CN101801391B
CN101801391B CN2008801063138A CN200880106313A CN101801391B CN 101801391 B CN101801391 B CN 101801391B CN 2008801063138 A CN2008801063138 A CN 2008801063138A CN 200880106313 A CN200880106313 A CN 200880106313A CN 101801391 B CN101801391 B CN 101801391B
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days
purposes
hyaluronic acid
skin
molecular weight
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Chinese (zh)
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CN101801391A (zh
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A·布里辛
E·皮谢勒
J-M·赞姆
M·米利奥
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Institut National de la Sante et de la Recherche Medicale INSERM
Agro Industrie Recherches et Developpements ARD
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Institut National de la Sante et de la Recherche Medicale INSERM
Agro Industrie Recherches et Developpements ARD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Otolaryngology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CN2008801063138A 2007-07-23 2008-07-04 透明质酸在制备用于改善皮肤、眼和粘膜的保护功能的组合物中的用途 Expired - Fee Related CN101801391B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0705349A FR2919185B1 (fr) 2007-07-23 2007-07-23 Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses
FR0705349 2007-07-23
PCT/FR2008/000959 WO2009024677A2 (fr) 2007-07-23 2008-07-04 Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de la fonction de protection de la peau, de l'oeil et des muqueuses

Publications (2)

Publication Number Publication Date
CN101801391A CN101801391A (zh) 2010-08-11
CN101801391B true CN101801391B (zh) 2013-07-10

Family

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Family Applications (1)

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CN2008801063138A Expired - Fee Related CN101801391B (zh) 2007-07-23 2008-07-04 透明质酸在制备用于改善皮肤、眼和粘膜的保护功能的组合物中的用途

Country Status (9)

Country Link
US (1) US8895532B2 (https=)
EP (1) EP2167102B1 (https=)
JP (1) JP2010534225A (https=)
KR (1) KR20100059786A (https=)
CN (1) CN101801391B (https=)
BR (1) BRPI0814446A2 (https=)
ES (1) ES2588190T3 (https=)
FR (1) FR2919185B1 (https=)
WO (1) WO2009024677A2 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010003797A1 (en) * 2008-07-09 2010-01-14 Novozymes Biopharma Dk A/S Hyaluronic acid for corneal wound healing
FR2963240B1 (fr) * 2010-07-28 2013-03-15 Horus Pharma Composition a usage topique sans conservateur comprenant de l'acide hyaluronique
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
KR102238406B1 (ko) 2011-06-03 2021-04-08 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
ES2667854T3 (es) * 2011-07-07 2018-05-14 Holy Stone Healthcare Co., Ltd. Composición para uso en el tratamiento y la prevención de trastornos relacionados con la inflamación
TWI466675B (zh) 2011-09-16 2015-01-01 Univ China Medical 用於抑制發炎之醫藥組合物
CN102669681A (zh) * 2012-06-09 2012-09-19 东莞市照燕生物科技有限公司 一种保护胃肠粘膜的营养保健品
ES2627868T3 (es) 2012-10-25 2017-07-31 Mdt Int'l S.A. Composiciones mucoadhesivas que comprenden ácido hialurónico y quitosano para aplicación tópica
JP2015063510A (ja) * 2013-06-28 2015-04-09 キユーピー株式会社 肌の保湿機能向上に関わる保湿関連遺伝子発現促進剤
EP3328353B1 (en) 2015-07-27 2024-04-10 Mary Kay, Inc. Topical skin formulations
JP6718728B2 (ja) * 2016-04-06 2020-07-08 キユーピー株式会社 アンチポリューション剤およびアンチポリューション用皮膚外用組成物
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
CN115317504A (zh) * 2021-05-10 2022-11-11 傅毓秀 玻尿酸用于制备治疗急性呼吸窘迫症药剂的用途
WO2022236599A1 (zh) * 2021-05-10 2022-11-17 傅毓秀 玻尿酸用于制备治疗急性呼吸窘迫症药剂的用途
WO2022236585A1 (zh) * 2021-05-10 2022-11-17 傅毓秀 玻尿酸用于制备治疗肺纤维化药剂的用途
TWI816119B (zh) * 2021-05-10 2023-09-21 國立陽明交通大學 玻尿酸用於製備治療急性呼吸窘迫症藥劑之用途
WO2023079072A1 (en) 2021-11-05 2023-05-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of low molecular weight hyaluronic acid for the treatment of lung mucosal inflammation
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof
EP4683647A1 (en) * 2023-03-22 2026-01-28 Institut National de la Santé et de la Recherche Médicale Use of low molecular weight hyaluronic acid for promoting ciliated cell differentiation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166331A (en) * 1983-10-10 1992-11-24 Fidia, S.P.A. Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same
WO2000001394A1 (en) * 1998-07-06 2000-01-13 Fidia Advanced Biopolymers S.R.L. Biocompatible and biodegradable compositions containing hyaluronic acid and the derivatives thereof for the treatment of ulcers in the digestive apparatus
WO2002069984A2 (de) * 2001-03-02 2002-09-12 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Verwendung von hyaluronsäure-uroniden zur behandlung von entzündlichen vorgängen
WO2003049747A1 (de) * 2001-12-12 2003-06-19 Ursapharm Arzneimittel Gmbh & Co. Kg Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung
WO2006072243A1 (en) * 2005-01-03 2006-07-13 Novozymes Biopolymer A/S Hyaluronic acid fraction with moisturizing and anti-wrinkle properties

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US4303676A (en) * 1980-03-21 1981-12-01 Balazs Endre A Hyaluronate based compositions and cosmetic formulations containing same
US4517295A (en) * 1983-02-18 1985-05-14 Diagnostic, Inc. Hyaluronic acid from bacterial culture
JPS59219209A (ja) * 1983-05-28 1984-12-10 Kanebo Ltd 皮膚化粧料
IT1260148B (it) * 1992-04-17 1996-03-28 Fidia Spa Impiego di preparazioni di acido ialuronico per la formazione di tessuto osseo
DE10161149B4 (de) 2001-12-12 2007-03-08 Ursapharm Arzneimittel Gmbh & Co. Kg Verwendung von Heparin-haltigem Ophthalmikum
US7241456B2 (en) * 2002-10-25 2007-07-10 Australian Importers Ltd. Formulations for topical delivery of bioactive substances and methods for their use
FR2847818B1 (fr) * 2002-11-28 2008-04-04 Agro Ind Rech S Et Dev Ard Composition pharmaceutique a base d'acide hyaluronique
JP4576583B2 (ja) * 2005-03-22 2010-11-10 キユーピー株式会社 ヒアルロン酸またはその塩、およびその製造方法、ならびにこれを含有する化粧料および食品組成物

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166331A (en) * 1983-10-10 1992-11-24 Fidia, S.P.A. Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same
WO2000001394A1 (en) * 1998-07-06 2000-01-13 Fidia Advanced Biopolymers S.R.L. Biocompatible and biodegradable compositions containing hyaluronic acid and the derivatives thereof for the treatment of ulcers in the digestive apparatus
WO2002069984A2 (de) * 2001-03-02 2002-09-12 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Verwendung von hyaluronsäure-uroniden zur behandlung von entzündlichen vorgängen
WO2003049747A1 (de) * 2001-12-12 2003-06-19 Ursapharm Arzneimittel Gmbh & Co. Kg Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung
WO2006072243A1 (en) * 2005-01-03 2006-07-13 Novozymes Biopolymer A/S Hyaluronic acid fraction with moisturizing and anti-wrinkle properties

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Publication number Publication date
EP2167102A2 (fr) 2010-03-31
JP2010534225A (ja) 2010-11-04
BRPI0814446A2 (pt) 2015-01-06
EP2167102B1 (fr) 2016-05-25
FR2919185A1 (fr) 2009-01-30
US20100210585A1 (en) 2010-08-19
FR2919185B1 (fr) 2010-09-10
WO2009024677A3 (fr) 2009-12-03
KR20100059786A (ko) 2010-06-04
ES2588190T3 (es) 2016-10-31
HK1145149A1 (en) 2011-04-08
US8895532B2 (en) 2014-11-25
WO2009024677A2 (fr) 2009-02-26
CN101801391A (zh) 2010-08-11

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