CN101785834B - Traditional Chinese medicine combination and preparation method thereof for renal insufficiency treatment - Google Patents
Traditional Chinese medicine combination and preparation method thereof for renal insufficiency treatment Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine combination and a preparation method thereof for renal insufficiency treatment; the traditional Chinese medicine combination includes the following raw medicines: ginseng, codonopsis pilosula, Chinese yam, crude raidx astragali, white paeony root, medicated leaven, burnt areca-nut, burnt hawthorn, prepared rehmannia root, liriope, medlar, fructus rosae laevigatae, cuttlebone, eucommia ulmoides, the seed of Chinese dodder, semen allii tuberosi, fructus alpiniae oxyphyllae, turtle shell, tortoise plastron, semen euryales, cordyceps sinensis, borneol and venenum bufonis. The traditional Chinese medicine combination can be prepared into any type of common oral preparation according to the conventional traditional Chinese medicine preparation method. The invention can significantly improve the symptoms of malaise, listlessness, loss of appetite, low immunity, edema, urinary incontinence, loss of libido, insomnia, and also can significantly improve the hypertension, gout, renal failure, uremia and other diseases having serious influence on life and living caused by renal insufficiency; the invention has definite clinical curative effect, significant curative and quick effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of thereof for renal insufficiency.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment thereof for renal insufficiency of crude drug with the Chinese herbal medicine.
Background technology
Kidney disease, general disturbance of blood circulation, general metabolism obstacle and urinary tract illness etc. all may cause dissimilar renal insufficiencys, mainly showing as metabolite accumulates in vivo, water, electrolyte and acid base imbalance, and with the urine amount and urine matter change and renal endocrine function obstacle cause a series of pathophysiological change.Prognosis is serious, is one of life-threatening main disease, and its PD is rapid, easily cause hypertension, gout, renal failure, uremia, etc. the multiple disease that has a strong impact on life and life, the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine adopts Drug therapys such as hormones at present, side effect is very big, therapeutic effect is limited, can only take stopgap measures and to effect a permanent cure, the state of an illness repeatedly, the patient suffering can't bear, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines, treating both the principal and secondary aspects of a disease of Chinese traditional treatment renal insufficiency, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out blood circulation promoting and blood stasis dispelling, dampness removing the turbid descending, regulating functional activities of qi, the bright natural plant of sun of removing heat by catharsis, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment renal insufficiency that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment thereof for renal insufficiency of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of thereof for renal insufficiency of the present invention, the component of main following weight portion is formed:
Radix Ginseng 1～30 gram, Radix Codonopsis 1～50 gram, Rhizoma Dioscoreae 1～50 gram, Radix Astragali 1～50 gram, the Rhizoma Atractylodis Macrocephalae 1～40 gram, the Radix Paeoniae Alba 1～40 gram, Massa Medicata Fermentata 1～50 gram, Endothelium Corneum Gigeriae Galli 1～30 gram, Fructus Hordei Germinatus 1～40 gram, Semen Arecae Prepareta 1～30 gram, Fructus Crataegi (parched to brown) 1～30 gram, Rhizoma Acori Graminei 1～50 gram, Radix Rehmanniae Preparata 1～40 gram, Radix Adenophorae (Radix Glehniae) 1～40 gram, Radix Ophiopogonis 1～40 gram, Fructus Lycii 1～50 gram, Fructus Ligustri Lucidi 1～30 gram, Fructus Schisandrae Chinensis 1～30 gram, Fructus Corni 1～40 gram, Fructus Rosae Laevigatae 1～40 gram, Endoconcha Sepiae 1～40 gram.
Be preferably:
Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Fructus Hordei Germinatus 20 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
The Cortex Eucommiae 1～30 gram, Radix Dipsaci 1～30 gram, Semen Cuscutae 1～30 gram, Semen Allii Tuberosi 1～30 gram, Fructus Alpiniae Oxyphyllae 1～40 gram, Herba Cistanches 1～40 gram, Herba Dendrobii 1～40 gram, Rhizoma Polygonati Odorati 1～40 gram, Radix Asparagi 1～50 gram, Carapax Trionycis 1～30 gram, Carapax et Plastrum Testudinis 1～30 gram, Fructus Mume 1～40 gram, Semen Euryales 1～40 gram, Ootheca Mantidis 1～40 gram, Cordyceps 1～30 gram, Borneolum Syntheticum 1～20 gram, Venenum Bufonis 1～10 gram.
Be preferably:
The Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Herba Dendrobii 20 grams, Rhizoma Polygonati Odorati 20 grams, Radix Asparagi 30 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Fructus Mume 30 grams, Semen Euryales 30 grams, Ootheca Mantidis 20 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.This is the important content of Thailand one and Pu (Beijing) Chinese medicine academy patent strategy.
The structure of Thailand one and Pu patent strategy is convenient to Chinese medicine and is realized standardization, scale, industrialization, modernization and industrialization.For traditional Chinese medicine development has been opened up a road that meets the Chinese medicine self-law with innovation.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the thereof for renal insufficiency patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams, the Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Semen Euryales 30 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams, the Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Semen Euryales 30 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams, the Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Semen Euryales 30 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams.Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams, the Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Semen Euryales 30 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams.Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams, the Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Semen Euryales 30 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams.Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating thereof for renal insufficiency of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 274 routine patients altogether, wherein male 196 examples, women 78 examples; The oldest person 65 years old, the age reckling has only 10 years old.
Two, Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 6 courses of treatment altogether.
Three, therapeutic evaluation standard
Cure: whole body is strong, and is in high spirits, and appetite is normal, and edema, urinary incontinence disappear, and are highly sexed, and insomnia and dreamful sleep takes a turn for the better, and sign is improved fully, and the patient does not have any bad sensation, and is happy, in high spirits.
Produce effects: whole body is obviously strong, and is in high spirits, and appetite is normal substantially, and edema, urinary incontinence disappear substantially, and insomnia and dreamful sleep takes a turn for the better, and sign is significantly improved, and the patient does not have big bad sensation, and is happy, and spirit better.
Effectively: whole body is more preceding strong, and appetite is obviously improved, and edema, urinary incontinence alleviate, and insomnia and dreamful sleep takes a turn for the better, and sign makes moderate progress, and patient's idol has uncomfortable sensation, and spirit takes a turn for the better.
Invalid: sign does not have any change, symptom such as preceding, malaise, lassitude.
Four, model case:
1, thanks certain, man, 58 years old, peasant.
Two renal calculus histories are arranged, tachypnea 2 wheat harvesting periods, with work and motion postemphasis, face is impractical, foot edema 1 month, back and the sense of shoulder arm fear of cold are obvious, two weakness of the lower extremitiess, fear of cold usually, in time, coughed, and tears are many, and urine is long and many, the more desire temperature of xerostomia drinking-water, have a liking for cigarette, arteries and veins: a left side is heavy thin and little, right thin string, light red tongue is fat tender, the thick, yellow and greasy fur profit, Sublingual narrowing toward each end blood vessel is abound with, and body is thin partially, the black yellow Shaoze of face and slightly impractical.Take Chinese medicine composition of the present invention after 15 days, edema obviously alleviates, continuous clothes Chinese medicine composition of the present invention 1 month, and edema disappears, and urine is normal, and various symptoms are significantly alleviated, and it is surplus to take Chinese medicine composition of the present invention 3 months again, and various symptoms all disappear, and are energetic.
2, Zhao, man, 36 years old, office worker.
The patient is no obvious inducement appearance headache before 1 year, is pollex, does not have dizziness, no face, eyes face and edema of pair of lower extremities, and tame at the most hospital therapy is all treated with cervical spondylosis.Malaise appears in no obvious inducement before 8 months, measuring blood pressure 210/120mmHg, and albumen 2+ has a routine urine test, renal function serum creatinine 3.9mg/dL, blood urea nitrogen 32.4 mg/dL, uric acid 7.6 mg/dL, two kidney B ultrasonic show left kidney 8.6 * 4.8 * 4.7cm, right kidney 9.7 * 5.0 * 4.6cm.Take Chinese medicine composition of the present invention after 15 days, uncomfortable symptom is significantly alleviated, the chemical examination urine protein+, edema alleviates, and continuous clothes Chinese medicine composition of the present invention is after 15 days, and edema disappears, continuous clothes Chinese medicine composition of the present invention is after 1 month, the chemical examination urine protein disappears renal function serum creatinine 2.0mg/dL, blood urea nitrogen 25 mg/dL, uric acid 6.6 mg/dL, took Chinese medicine composition of the present invention again 2 months, the every index full recovery of health is normal, returns to one's perfect health.
3, Zhang, woman, 35 years old, teacher.
Malaise, dreaminess, inappetence, vomiting and nausea is surplus May, blood pressure 200/120mmhg, the anemia looks, palpebral conjunctiva is pale, pale tongue, yellow fur is thick, and neck is soft, two lung audibles and wheezing sound, heart circle is bigger than normal, heart rate 86 times/minute, rule is neat, and is strong, mitral area audible and shrink 3/6 phase level blowing murmur, abdomen is flat soft, no tenderness, and two lower limb are not seen edema.Take Chinese medicine composition of the present invention after 1 month, symptom is significantly alleviated, and continuous clothes Chinese medicine composition of the present invention is after 1 month, and blood pressure, heart rate recover normal, take 3 first quarter moons of Chinese medicine composition of the present invention again, and various symptoms all disappear, and follow up a case by regular visits to so far, do not have recurrence.
4, Wang, man, 33 years old, manager.
The patient occurred weak before 1 year, felt sick appetite decline symptom, do not arouse attention, serum creatinine occurs after back patient Yu Si month and raise anasarca, be sent to local county hospital, still continue to rise through treatment back serum creatinine, blood urea nitrogen, and the aggravation of edema situation.Take Chinese medicine composition of the present invention after 20 days, various symptoms are all to effectively control, and continuous clothes Chinese medicine composition of the present invention is after 1 month, edema disappears substantially, symptom is significantly alleviated, and continuous clothes Chinese medicine composition of the present invention is after 1 month, and edema disappears, blood test creatinine, blood urea nitrogen are substantially near normal value, take 1 first quarter moon of Chinese medicine composition of the present invention again, various symptoms all disappear, and return to one's perfect health, then repeatedly check renal function, index is all within normal range.
5, Wu, man, 12 years old.
Just suffered from nephritis before 4 years, the household is very worried, is with its many hospitals that pass by, Chinese and western medicine has all been seen, but effect is not remarkable, the doctor trained in Western medicine prednisone, cause edema of the face severity afterwards, the patient is afraid of cold especially, and adding after looking for the traditional Chinese medical science to see is cold-damp, with medicines such as stomach Siberian cocklebur soup and Radix Saposhnikoviae Rhizoma Et Radix Notopterygiis, delude again in saying that nephropathy should be mended, Carnis Haliotidis commonly used, Air Bladder pseudosciaenae seu Acipenser are stewed foods such as Ren sus domestica, and disease is satisfied and touchingly do not healed, patient's edema of the face and red, look tired, readme has dizziness and blurred vision, and muscle is miserable, irritated dry pharynx, mouth has the ammonia flavor, anorexia, stringy and rolling pulse is counted accurately, and red tongue with yellowish and greasy fur is turbid.Take Chinese medicine composition of the present invention after 15 days, the edema of the face significantly alleviates, and continuous clothes Chinese medicine composition of the present invention is after 15 days, patient's edema almost all disappears, and is energetic, and symptom is significantly alleviated, continuous clothes Chinese medicine composition of the present invention is surplus March, thoroughly rehabilitation, not recurrence so far.
6, journey, woman, 54 years old, accounting.
Before the patient comes from 10 years, the serious edema of whole body, transference cure behind the oral Chinese herbal medicine, the two lower limb discontinuity edema in back are not given attention.Looked into urine before 6 years, urine protein positive is checked the situation of turning out cloudy later on, occurs anemia before February, and it is poor to sleep, inappetence, and xerosis cutis feels run-down, hypohidrosis, the urine amount is normal, and color is light, and is tasteless.Take Chinese medicine composition of the present invention after 1 month, symptom is significantly improved, and it is surplus March to take Chinese medicine composition of the present invention again, and all transference cures with examining 2 years, do not have recurrence.
7, Zhao, man, 53 years old, workman.
Previously hypertension, hyperlipidemia and coronary disease medical history are arranged, this shows as progressivity renal insufficiency and nephropathy scope albuminuria.Serum creatinine increased to present 3.1mg/dl from 1.5 of last year.The albuminuria medical history several months, present 7 g/24 hrs.Urine examination is shown: 4+ protein.Take Chinese medicine composition of the present invention after 1 month, the chemical examination urine protein +++, 3 g/24 hrs, serum creatinine 2.8 mg/dl, continuous clothes Chinese medicine composition of the present invention 1 month, the chemical examination urine protein+, 0.5 g/24 hrs, serum creatinine 1.5 mg/dl, it is surplus March to obey Chinese medicine composition of the present invention again, physical recovery health, through comprehensive inspection of authoritative hospital, the result is normal fully.
8, Guo, woman, 41 years old, peasant.
The patient before 2 years no obvious inducement face and edema of pair of lower extremities (being pitting) appear, dizziness has tangible spinning sensation.Going into local hospital looks into: blood pressure 180/100mmHg, urine protein (+++), ERY (+++), serum creatinine 171umol/L, blood urea nitrogen 15.6mmol/L, hematochrome 85g/L.The patient is because of the household economy difficulty, the oral local folk prescription treatment of the discontinuity of being in, self perceptual difference, weak obviously, edema always not be improved significantly.Take Chinese medicine composition of the present invention after 15 days, edema significantly alleviates, and continuous clothes Chinese medicine composition of the present invention is after 1 month, blood pressure 140/90mmHg, urine protein (++), ERY (+), serum creatinine 130.5umol/L, blood urea nitrogen 9.3mmol/L, hematochrome 40g/L continues clothes Chinese medicine composition of the present invention after 1 month, blood pressure 140/80mmHg, urine protein (+), ERY (+), serum creatinine 110.3umol/L, blood urea nitrogen 7.5mmol/L, hematochrome 23g/L, take 3 first quarter moons of Chinese medicine composition of the present invention again, various symptoms all disappear, and return to one's perfect health, then repeatedly check renal function, index is all within normal range.
Five, therapeutic outcome:
In the 274 routine cases of being accepted for medical treatment,, wherein cure 187 examples through treatment in 6 months, produce effects 36 examples, effective 45 examples, invalid 6 examples, total effective rate reaches 97.8%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment thereof for renal insufficiency patient.
Claims (2)
1. preparation for the treatment of the Chinese medicine composition of renal insufficiency disease, it is characterized in that: this Chinese medicine composition is made up of following bulk drugs: Radix Ginseng 10 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae 30 grams, Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Paeoniae Alba 20 grams, Massa Medicata Fermentata 30 grams, Endothelium Corneum Gigeriae Galli 15 grams, Semen Arecae Prepareta 15 grams, Fructus Crataegi (parched to brown) 15 grams, Rhizoma Acori Graminei 30 grams, Radix Rehmanniae Preparata 20 grams, Radix Adenophorae (Radix Glehniae) 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Ligustri Lucidi 15 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Corni 15 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 20 grams, the Cortex Eucommiae 20 grams, Radix Dipsaci 15 grams, Semen Cuscutae 15 grams, Semen Allii Tuberosi 15 grams, Fructus Alpiniae Oxyphyllae 20 grams, Herba Cistanches 15 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Semen Euryales 30 grams, Cordyceps 10 grams, Borneolum Syntheticum 6 grams, Venenum Bufonis 5 grams, the dosage form of this Chinese medicine composition is selected from pill, capsule, tablet, granule or oral liquid.
2. the application of the preparation of Chinese medicine composition according to claim 1 in preparation treatment incomplete renal function disease drug.
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| CN103599397B (en) * | 2013-11-12 | 2015-09-02 | 陈维娜 | A kind of Chinese medicine composition being used for the treatment of chronic renal insufficiency |
| CN106616968A (en) * | 2016-09-21 | 2017-05-10 | 中国科学院西北高原生物研究所 | Healthcare food capable of relieving gout symptoms |
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|---|---|---|---|---|
| CN1660404A (en) * | 2005-01-19 | 2005-08-31 | 雷小平 | Health product of preserving health, invigorating the kidney and supporting yang for male |
| CN1682982A (en) * | 2005-02-22 | 2005-10-19 | 黄资源 | Yishenkangshuai pill for treating chronic nephrosis and renal failure |
-
2009
- 2009-10-30 CN CN2009103091675A patent/CN101785834B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660404A (en) * | 2005-01-19 | 2005-08-31 | 雷小平 | Health product of preserving health, invigorating the kidney and supporting yang for male |
| CN1682982A (en) * | 2005-02-22 | 2005-10-19 | 黄资源 | Yishenkangshuai pill for treating chronic nephrosis and renal failure |
Non-Patent Citations (2)
| Title |
|---|
| 熊群芝.中西医结合治疗肾功能不全.《湖北中医杂志》.1999,第21卷(第7期),317. * |
| 范立干等.中西医结合治疗慢性肾功能不全19例疗效观察.《交通医学》.1994,第8卷(第4期),40. * |
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| Publication number | Publication date |
|---|---|
| CN101785834A (en) | 2010-07-28 |
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