CN101785810B - Traditional Chinese medicine preparation for anaphylactoid purpura treatment - Google Patents
Traditional Chinese medicine preparation for anaphylactoid purpura treatment Download PDFInfo
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- CN101785810B CN101785810B CN2010101008695A CN201010100869A CN101785810B CN 101785810 B CN101785810 B CN 101785810B CN 2010101008695 A CN2010101008695 A CN 2010101008695A CN 201010100869 A CN201010100869 A CN 201010100869A CN 101785810 B CN101785810 B CN 101785810B
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Abstract
The invention discloses a traditional Chinese medicine preparation for anaphylactoid purpura treatment, which is prepared by the following raw materials (by weight part): 9-12 parts of scutellaria baicalensis, 10-12 parts of fructus forsythiae, 12-15 parts of root bark of the peony tree, 9-15 parts of astragalus mongholicus, 9-12 parts of radix sophorae flavescentis, 10-30 parts of pagoda tree flower, 10-15 parts of the root of red-rooted salvia, 10-30 parts of root of rehmannia, 6-9 parts of folium artemisiae argyi and 3-10 parts of crude liquorice. The traditional Chinese medicine preparation has the efficacies of clearing heat and cooling blood, removing stasis and eliminating spots, also has the efficacies of immunity regulation and healthy energy support, and accordingly obtains good curative effect. The traditional Chinese medicine preparation has significant curative effect on the treatment of anaphylactoid purpura, has no obvious side effect during treatment, adopts cheap raw materials, is applicable to common people and is suitable for clinical observation and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of anaphylactoid purpura.
Background technology
Anaphylactoid purpura, be body to some sensitizer generation allergy, cause capillary fragility and permeability to increase, a kind of common hemorrhage of skin purpura, mucosa and some organ hemorrhage appears in blood extravasation.Clinical characters often has erythra and vasodilation, joint swelling and pain, stomachache and renal albuminuria etc. except that the skin purpura.Be more common in child and teenager.The generation of anaphylactoid purpura is except that the allergic constitution of self, and the influence of outside paathogenic factor is that indispensable essential condition takes place disease.Immune complex deposit in tunica intima, damage little blood vessel, blood capillary and arteriolitis widely take place, even necrotizing arteriolitis.Blood vessel wall permeability and fragility increase, and perivascular infiltration and blood plasma sample ooze out.The treatment of primary disease except that eliminating the cause of disease, is often used Claritin, is reduced treatments such as vascular permeability medicine, anticoagulant medicine, adrenocortical hormone, immunosuppressant clinically.In using the hormone therapy process, because factor affecting such as body constitution and environmental changes, regular meeting has a rebound or the state of an illness adds reconstructed image.
Summary of the invention
At above-mentioned prior art, the invention provides a kind of Chinese medicine preparation of the treatment anaphylactoid purpura that does not rebound, has no side effect.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine preparation for the treatment of anaphylactoid purpura, make by following bulk drugs: 9～12 parts of Radix Scutellariaes, 10～12 parts of Fructus Forsythiaes, 12～15 parts of Cortex Moutans, 9～15 parts of the Radixs Astragali, 9～12 parts of Radix Sophorae Flavescentiss, 10～30 parts of Flos Sophorae, 10～15 parts of Radix Salviae Miltiorrhizaes, 10～30 parts in the Radix Rehmanniae, 6～9 parts of Folium Artemisiae Argyis, 3～10 parts of Radix Glycyrrhizae.
Preferably, make: Radix Scutellariae 10g, Fructus Forsythiae 11g, Cortex Moutan 13g, Radix Astragali 12g, Radix Sophorae Flavescentis 10g, Flos Sophorae 20g, Radix Salviae Miltiorrhizae 13g, Radix Rehmanniae 20g, Folium Artemisiae Argyi 8g, Radix Glycyrrhizae 6g by following crude drug.
During treatment, routine is decocted in water for oral dose, every day 2 times, and 1 dose of every day (1 dose drug dose is the amount of preferred prescription), each 1 time sooner or later, clothes 100ml, serveing on 7 days is 1 course of treatment.Dose also can be done among a small circle adjustment according to age, body constitution, state of an illness weight etc. in the side.
The pharmacological effect of medicine of the present invention is as follows: anaphylactoid purpura belongs to the traditional Chinese medical science " blood disorder " " purpura " " hematohidrosis " " hemorrhagic disease with purpura " category, how can not have under one's command due to the blood owing to pathogenic heat injure blood network, the absurd row of forcing blood or the deficiency of vital energy.Anaphylactoid purpura is clinical sees so that the absurd passerby of pathogenic heat forcing blood more.So clinical treatment is many to be main Therapeutic Principle with clearing away heat and cooling blood.On the basis of this rule of treatment, according to this sick pathological characteristic, promptly capillary permeability, fragility strengthen, and in conjunction with Chinese medicine, prescription modern pharmacology and clinical research, the inventor drafts out this prescription.
Pharmacological action: Radix Scutellariae, antiallergic action suppresses capillary permeability.Fructus Forsythiae, Flos Sophorae contain rutin, can reduce capillary permeability, increase the blood capillary density.The Cortex Moutan blood circulation promoting and blood stasis dispelling has the enhancing blood flow, and microcirculation improvement is regulated immunologic function,, and the antagonism radical damage,, allergy alleviated.To preventing that the purpura recurrence from having preventive effect preferably.Radix Sophorae Flavescentis suppresses mastocyte and discharges histamine.Folium Artemisiae Argyi reduces capillary permeability, antiradiation drug and day photosensitivity.Radix Glycyrrhizae suppresses egg albumen, horse serum sensitization.The modern pharmacological research Radix Astragali can increase capillary resistance, and blood vessel dilating improves blood circulation, have two-way immunoregulation effect, can significantly reduce protein content in the urine, promote the removing of immune complex, henoch Schonlein purpura nephritis is had better curative effect, and its mechanism of action remains further to be studied.The Radix Rehmanniae replenishing YIN and removing heat, cooling blood for hemostasis, coronary artery dilator.Radix Salviae Miltiorrhizae can improve capillary permeability, regulates human body immune function, increases the anoxybiotic ability of antibody tissue tolerance.
Chinese medicine preparation of the present invention can be regulated immunity simultaneously based on clearing away heat and cooling blood, eliminating blood stasis and removing ecchymoses, strengthening the body resistance, thereby obtain good the effect.Drug therapy anaphylactoid purpura determined curative effect of the present invention.Do not find apparent side effect in the treatment.And each cost of material is cheap, is applicable to the general population, is worth clinical observation to be used.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment and clinical data:
A kind of Chinese medicine preparation for the treatment of anaphylactoid purpura of embodiment 1 preparation
Prescription is: Radix Scutellariae 9g, Fructus Forsythiae 12g, Cortex Moutan 12g, Radix Astragali 15g, Radix Sophorae Flavescentis 9g, Flos Sophorae 30g, Radix Salviae Miltiorrhizae 10g, Radix Rehmanniae 30g, Folium Artemisiae Argyi 6g, Radix Glycyrrhizae 10g.
When taking, routine is decocted in water for oral dose, every day 2 times, and 1 dose of every day, each 1 time sooner or later, the about 100ml of each clothes, serveing on 7 days is 1 course of treatment.Can fully recover after general two courses of treatment.
A kind of Chinese medicine preparation for the treatment of anaphylactoid purpura of embodiment 2 preparations
Prescription is: Radix Scutellariae 12g, Fructus Forsythiae 10g, Cortex Moutan 115g, Radix Astragali 9g, Radix Sophorae Flavescentis 12g, Flos Sophorae 10g, Radix Salviae Miltiorrhizae 15g, Radix Rehmanniae 10g, Folium Artemisiae Argyi 9g, Radix Glycyrrhizae 3g.
When taking, routine is decocted in water for oral dose, every day 2 times, and 1 dose of every day, each 1 time sooner or later, the about 100ml of each clothes, serveing on 7 days is 1 course of treatment.Can fully recover after general two courses of treatment.
A kind of Chinese medicine preparation for the treatment of anaphylactoid purpura of embodiment 3 preparations
Prescription is: Radix Scutellariae 10g, Fructus Forsythiae 11g, Cortex Moutan 13g, Radix Astragali 12g, Radix Sophorae Flavescentis 10g, Flos Sophorae 20g, Radix Salviae Miltiorrhizae 13g, Radix Rehmanniae 20g, Folium Artemisiae Argyi 8g, Radix Glycyrrhizae 6g.
When taking, routine is decocted in water for oral dose, every day 2 times, and 1 dose of every day, each 1 time sooner or later, the about 100ml of each clothes, serveing on 7 days is 1 course of treatment.Can fully recover after general two courses of treatment.
Clinical data:
(1) patient's data: patient's 60 examples, be first morbidity, male 40 examples, women 20 examples, 6～13 years old 43 example, 14～25 years old 17 example, the course of disease 1～5d, 60 examples are skin-type, skin joint type 15 examples of holding concurrently wherein, abdomen type 10 examples of holding concurrently, kidney type 12 examples of holding concurrently.
(2) therapeutic modality: the patient takes the medicine among the embodiment 1, and treatment 7d was 1 course of treatment, judged curative effect after 2 courses of treatment.
(3) criterion of therapeutical effect: clinical symptoms and sign complete obiteration, renal function and uroscopy are normal, and drug withdrawal is observed 3 months no recidivists for curing; Clinical symptoms and sign disappear, and renal function is normal, the uroscopy urine protein (±～+) or erythrocyte (±～+) be produce effects; Clinical symptoms and sign disappear substantially, and renal function is normal, and uroscopy urine protein (+) or erythrocyte (+) are for taking a turn for the better; Through treat 2 all disease nothings transfer to invalid.
(4) therapeutic outcome; Patient's 60 examples are cured 55 examples, produce effects 2 examples, 1 example that takes a turn for the better, invalid 2 examples, cure rate 91.67%, effective percentage 96.66%.
Case:
Case 1: patient Liu, man 16 years old, student, first visit on March 2 in 2007.The main suit: purpura show effect repeatedly 1 year surplus.Disease is seen: extremity skin purpura, and obvious with two lower limb, be speckle mound sample, differ in size, color is purple black, is distributed symmetrically, that presses is colour-fast, and this heals that, companion's pruritus scratch, companion's double knee joint pain, tired mind, limbs fatigue, the time hematuria is arranged, purplish tongue is dark, point has petechia, stringy and hesitant pulse, repeatedly have a blood test platelet and coagulation function are all normal.Be diagnosed as: anaphylactoid purpura.Serve on two courses of treatment with medicine of the present invention, purpura is all disappeared, and simultaneous phenomenon all disappears; Follow up a case by regular visits to half a year, do not see recurrence.
Case 2: patient Zhang, woman, 15 years old.Before two lower limb purpura appears, color and luster is scarlet, erythra is intensive, needle point is to Semen Viciae fabae size, xerostomia, constipation with dry stool, red tongue with yellow fur, floating and rapid pulse.Control suitable clearing away heat and cooling blood, eliminating blood stasis and removing ecchymoses, give drug oral of the present invention.Take medicine after 1 week, skin lesion obviously alleviates, and xerostomia, constipation with dry stool disappear.The 2 all backs symptom and signs of taking medicine all disappear, and 1 week of continuing to take medicine is consolidated curative effect.Follow up a case by regular visits to half a year, do not see recurrence.
Case 3: the patient village, the man, 12 years old, on January 13rd, 2008 was paroxysmal with stomachache, and the companion feels sick, and black stool matter is rare, and extremity are dispersed in the granular petechia of foxtail millet, and partial fusion is in blocks, and that touches is in the way.Not having heating, swells and ache in no joint.Have a medical check-up: mind is clear, and lassitude, extremity are dispersed in the symmetry petechia, and lower limb are many especially, the hyperemia of bilateral bulbar conjunctiva.Cardiopulmonary are checked no abnormal, and abdomen is soft, all tenderness of umbilicus, and no rebound tenderness, two kidneys district does not have percussion pain.Neurologic check is not drawn pathologic reflex.Red tongue, yellow, greasy and thin fur, stringy and tense pulse.Lab testing: routine blood test WBC 14.5 * 109/L, N 0.83, Hb 138g/L, PLT 220 * 109/L, bleeding time 2min, clotting time 4min; Urine is conventional: urine protein (++), erythrocyte (+), stool blood (++); B ultrasonic shows: two kidney forms are full to be increased slightly, irregular low echo in the kidney, the infringement of prompting excess of the kidney light weight degree.Once give treatment 3d such as penicillin, dexamethasone, chlorphenamine, Anisodamine in local clinic and do not have improvement.Give and drug oral of the present invention, the same day, stomachache promptly alleviated, and can tolerate.7d, erythra goes down, stomachache disappears, only two lower limb are seen and are dispersed in the remote hemorrhage point, deflorescence behind the 14d, diet can, the defecation chemical examination is normal, routine blood test WBC8.6 * 109/L, N 0.69, L 0.33, Hb 145g/L, PLT170 * 109/L.Advise the two yellow stuff first quarter moons of the clothes that continue, follow up a case by regular visits to half a year, do not see recurrence.
Claims (2)
1. Chinese medicine preparation for the treatment of anaphylactoid purpura, it is characterized in that, make: 9～12 parts of Radix Scutellariaes, 10～12 parts of Fructus Forsythiaes by following bulk drugs, 12～15 parts of Cortex Moutans, 9～15 parts of the Radixs Astragali, 9～12 parts of Radix Sophorae Flavescentiss, 10～30 parts of Flos Sophorae, 10～15 parts of Radix Salviae Miltiorrhizaes, 10～30 parts in the Radix Rehmanniae, 6～9 parts of Folium Artemisiae Argyis, 3～10 parts of Radix Glycyrrhizae.
2. a kind of Chinese medicine preparation for the treatment of anaphylactoid purpura according to claim 1, it is characterized in that: make: 10 parts of Radix Scutellariaes by following bulk drugs, 11 parts of Fructus Forsythiaes, 13 parts of Cortex Moutans, 12 parts of the Radixs Astragali, 10 parts of Radix Sophorae Flavescentiss, 20 parts of Flos Sophorae, 13 parts of Radix Salviae Miltiorrhizaes, 20 parts in the Radix Rehmanniae, 8 parts of Folium Artemisiae Argyis, 6 parts of Radix Glycyrrhizae.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102266444A (en) * | 2011-07-19 | 2011-12-07 | 内蒙古自治区中蒙医医院 | Medicament for treating anaphylactoid purpura |
| CN103083570B (en) * | 2012-12-11 | 2014-04-16 | 宋协勘 | Traditional Chinese medicine for treating anaphylactoid purpura |
| CN104435429A (en) * | 2014-11-30 | 2015-03-25 | 孙晓兵 | Traditional Chinese medicine composition for treating anaphylactoid purpura |
| CN105012505A (en) * | 2015-08-11 | 2015-11-04 | 刘雪强 | Medicine for treating allergic purpura |
| CN106176379A (en) * | 2016-08-09 | 2016-12-07 | 思拓科（上海）生物科技股份有限公司 | A kind of cosmetics, its preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1824203A (en) * | 2005-12-22 | 2006-08-30 | 夏金陵 | Heat clearing toxin resolving medicine for treating psora and its preparation method |
| CN101313991A (en) * | 2008-07-01 | 2008-12-03 | 王跃进 | Capsule for thrombocytopenic purpura |
| CN101549066A (en) * | 2009-04-17 | 2009-10-07 | 吉林天药现代中药科技有限公司 | Prescription for treating allergy purpura and method for preparing same |
-
2010
- 2010-01-26 CN CN2010101008695A patent/CN101785810B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1824203A (en) * | 2005-12-22 | 2006-08-30 | 夏金陵 | Heat clearing toxin resolving medicine for treating psora and its preparation method |
| CN101313991A (en) * | 2008-07-01 | 2008-12-03 | 王跃进 | Capsule for thrombocytopenic purpura |
| CN101549066A (en) * | 2009-04-17 | 2009-10-07 | 吉林天药现代中药科技有限公司 | Prescription for treating allergy purpura and method for preparing same |
Non-Patent Citations (6)
| Title |
|---|
| 冯胜奎等.复方中药治疗过敏性紫癜30例疗效观察.《新中医》.2008,第40卷(第01期),58-59. * |
| 孙虎生.紫丹益肾汤治疗过敏性紫癜性肾炎40例.《陕西中医》.2005,第26卷(第12期),1290-1292. * |
| 李彩霞等.清热解毒凉血法治疗过敏性紫癜72例.《陕西中医》.2006,第27卷(第12期),1518-1519. * |
| 王桓朝.皮炎汤治疗皮肤病验案.《北京中医》.1990,(第03期),4-5. * |
| 陈惠华.过敏性紫癜性肾炎中医药治疗进展.《福建中医学院学报》.2005,第15卷23-25. * |
| 韩翠翠,等.中医辨证论治小儿紫癜性肾炎的研究进展.《云南中医中药杂志》.2008,第29卷(第9期),61-63. * |
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