CN101757573B - Traditional Chinese medicine composition for treating memory loss and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating memory loss and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a new traditional Chinese medicine composition for treating memory loss and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw medicinal herbs: fructus alpiniae oxyphyllae, rhizoma acori graminei, dangshen, angelica sinensis, raw astragalus mongholicus, ginseng, radix paeoniae alba, root of common peony, ligusticumwallichii, radix salviae miltiorrhizae, chrysanthemum, root of kudzu vine, radix angelicae, prepared rehmannia root, motherwort, rhizoma sparganii, curcuma zedoary, cortex albiziae, polygala tenuifolia, styrax Asiatic styrax, white atractylodes rhizome, aweto, scutellaria baicalensis, polygonum multiflorum, red flower, radix curcumae and fruit of Chinese wolfberry. The traditional Chinese medicine composition can be prepared into any one oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can remarkably improve symptoms of hypomnesis, thinking logic disorder and incomplete language expression as well as memory loss, no recognition of family and relatives and friends, no capability of self-care life, changeable and violent characters in serious conditions, or dull spirit and the like, and has accurate clinical treatment effect, remarkable treatment effect and rapid effect taking.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of hypomnesis.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment hypomnesis of crude drug with the Chinese herbal medicine.
Background technology
Early stage, the factors such as mental work is excessive, anemia, congenital malformation, cerebral trauma sequela of total quality decline, dementia all can cause the generation of hypomnesis disease after age increased.Often show as: the thinking logic confusion, language performance is incomplete, forgets after the preceding note, and body constitution is not good; lassitude etc., the door is gone to the wrong way in memory loss when serious, and kith and kin do not distinguish; can't take care of oneself, personality changes hot-tempered impermanence or dull mind, and the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment hypomnesis disease, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out refreshment allay excitement, tonify Qi of the kidney, the invigorate blood circulation natural plant of brain-strengthening,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment hypomnesis that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment hypomnesis of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of hypomnesis of the present invention, the component of main following weight portion is formed:
1～150 part of Fructus Alpiniae Oxyphyllae, 1～150 part of Rhizoma Acori Graminei, 1～300 part of Radix Codonopsis, 1～150 part of Radix Angelicae Sinensis, 1～300 part of Radix Astragali, 1～50 part of Radix Ginseng, 1～150 part of the Radix Paeoniae Alba, 1～150 part of Radix Paeoniae Rubra, 1～150 part of Rhizoma Chuanxiong, 1～150 part of Radix Salviae Miltiorrhizae, 1～300 part of Rhizoma Dioscoreae, 1～300 part of Massa Medicata Fermentata, 1～300 part of Fructus Hordei Germinatus (parched to brown), 1～150 part of Cortex Magnoliae Officinalis, 1～100 part of Flos Chrysanthemi, 1～150 part of Radix Puerariae, 1～100 part of the Radix Angelicae Dahuricae, 1～150 part of Semen Euryales, 1～100 part of Semen Plantaginis, 1～150 part of Spora Lygodii, 1～300 part of Pericarpium Citri Reticulatae, 1～300 part of Rhizoma Cyperi, 1～150 part of Radix Rehmanniae Preparata, 1～150 part of Herba Leonuri, 1～50 part of rhizoma sparganic, 1～50 part of Rhizoma Curcumae, 1～100 part of Cortex Albiziae, 1～50 part of Radix Polygalae, 1～100 part of Styrax, 1～150 part of the Rhizoma Atractylodis Macrocephalae, 1～50 part of Cordyceps, 1～150 part of Radix Ophiopogonis, 1～150 part of Radix Asparagi, 1～50 part of Carapax Trionycis (processed), 1～50 part of Carapax Et Plastrum Testudinis (processed), 1～50 part of Fructus Ligustri Lucidi, 1～100 part of Radix Scutellariae, 1～150 part of Herba Cistanches, 1～50 part of Rhizoma Cibotii.
Be preferably:
100 parts of Fructus Alpiniae Oxyphyllae, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 30 parts of Semen Plantaginiss, 40 parts of Spora Lygodii, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 20 parts of Fructus Ligustri Lucidi, 30 parts of Radix Scutellariaes, 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
1～50 part of Radix Panacis Quinquefolii, 1～100 part of Semen Arecae Prepareta, 1～100 part of Fructus Psoraleae, 1～100 part of the Cortex Eucommiae, 1～50 part of Radix Dipsaci, 1～150 part of Radix Polygoni Multiflori, 1～50 part on Flos Carthami, 1～150 part of Radix Adenophorae (Radix Glehniae), 1～50 part in Lignum Santali Albi, 1～50 part of Benzoinum, 1～150 part of the Radix Linderae, 1～100 part in Rhizoma Curcumae Longae, 1～100 part of Semen Platycladi, 1～100 part of Concha Haliotidis, 1～50 part of Concha Margaritifera, 1～50 part of Camphora, 1～50 part of Borneolum Syntheticum, 1～100 part of Cortex Phellodendri, 1～100 part of Radix Et Rhizoma Rhei, 1～100 part of Herba Pogostemonis, 1～100 part of the Radix Aucklandiae, 1～100 part of Radix Curcumae, 1～150 part of Fructus Lycii.
Be preferably:
10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 50 parts of Concha Haliotidis, 10 parts of Concha Margaritiferas, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the hypomnesis patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: 100 parts of Fructus Alpiniae Oxyphyllae, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: 100 parts of Fructus Alpiniae Oxyphyllae, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: 100 parts of Fructus Alpiniae Oxyphyllae, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: 100 parts of Fructus Alpiniae Oxyphyllae, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: 100 parts of Fructus Alpiniae Oxyphyllae, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating hypomnesis of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 49 routine patients altogether, wherein male 28 examples, women 21 examples; The oldest person 79 years old, the age reckling has only 16 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 9 courses of treatment altogether.
The therapeutic evaluation standard
Cure: memory recovers normal, resourceful, clear thinking, and verbalization is complete, and is in high spirits, and diet and rest are normal, and mood is stable, and the patient does not have any bad sensation, and is happy, in high spirits.
Produce effects:: memory significantly is restored, and thinking is comparatively quick, and thinking is more clear, and verbal expression skill strengthens, and is in high spirits, and diet and rest are normal, and mood is stable, and the patient does not have big bad sensation, and is happy, in high spirits.
Effectively:: memory is recovered to some extent, and thinking improves, and thinking is more preceding distinct, and verbalization improves, and spirit is better, and diet and rest are normal substantially, and mood is more stable, and it is better that the patient feels.
Invalid: sign does not have any change, and symptom such as preceding feels depressed, and lethargy is depressed.
Model case:
1, Chen, man, 42 years old, driver.
Before March, originally normal memory generation serious degradation behind the brain trauma surgery is all forgotten from sick 5 to 6 months thing before, has not a particle of impression, more seriously, present thing has not been remembered yet, and is that whole things are not a bit remembered, and speaks and always repeats those several, ask him he says that his firm word is not had impression, just he just says and is having a dream occurrence for a moment, dreams what what, after just forgotten fully for a moment.
Took Chinese medicine composition of the present invention 15, hypomnesis makes moderate progress, continue and obeyed Chinese medicine composition of the present invention 1 month, thing at the moment can remember that mostly a former thing part can remember that memory before significantly improves, symptom is greatly taken on a new look, the clothes Chinese medicine composition of the present invention 3 months that continues, transference cure, memory recover as before.
2, poplar, woman, 73 years old, retired cadre.
The patient engendered hypomnesis before 5 years, showed as forgetful, obvious with nearly hypomnesis especially.After hypomnesis far away gradually appears, bradykinesia, verbigeration.Sx over nearly 6 months, dystropy, apathetic expression, relatives all are not familiar with at one's side sometimes.Spirit is poor when examining, malaise, osteodynia discomfort, and night is heavy especially, unable to fall asleep whole night, the appetite extreme difference, apathetic expression, orientation force, memory, judgment, computing power obviously go down, the speech minimizing.
Took Chinese medicine composition of the present invention 1 month, hypomnesis obviously improves, and cognitive competence improves, malaise, osteodynia are alleviated, and continue and obey Chinese medicine composition of the present invention 2 months, and memory significantly promotes, diet increases, and spirit takes a turn for the better, and sleep is fragrant, cognitive competence improves, the whole body osteodynia disappears, and continues and obeys Chinese medicine composition of the present invention 3 months, likes to speak with the people, initiatively greeting with the people exchanges, and the patient is conscious, and sign is better than ever.
3, Pan, man, 69 years old, professor.
March, cause was gone to nonlocal lecture tour, runs to come and go, and the road fatigue, spirit is extremely tired.The back memory of going home obviously fails, and answers very not pertinent to the pointly, and chaos is unclear all day, speaking scarcely,taciturn, and it is poor to sleep, and fears and other people speech, come all illness benefits heavy in nearly 2 weeks, apathetic expression occurs, words are put upside down, bradykinesia, lustreless complexion, witless expression is blunt in one's manner, white and thin fur, and matter is light fat partially, deep,thready and forceless pulse.
Took Chinese medicine composition of the present invention 15 days, spirit makes moderate progress, and sleeps night and can sleep peacefully 5～7 hours, continues and obeys Chinese medicine composition of the present invention 1 month, complexion is changeed profit, the consciousness reaction is normal, and memory makes moderate progress, and spirit is also shaken, answer and keep to the point, continue and obeyed Chinese medicine composition of the present invention 3 months, various symptoms all disappear, and patient's mental attitude is taken on an entirely new look.
4, Lee so-and-so, man, 67 years old, retired cadre.
The patient over nearly 2 years memory obviously go down, apathetic expression, bradykinesia, it is unclear to tell speech, sialorrhea is unsociable and eccentric, behavior is unusual sometimes.Examined preceding 10 days, insomnia appears in the patient, and excited language is many, speaking incoherently, and understanding, difficult judgment be can't take care of oneself, emotional fragility, memory obviously descends, and the body of the tongue purple is dim, greasy fur, deep and hesitant pulse.
Took Chinese medicine composition of the present invention 15 days, spirit makes moderate progress, and the sleep amelioration continues and obeyed Chinese medicine composition of the present invention 1 month, the state of an illness takes a turn for the better gradually, be emotionally stable, memory, faculty of understanding, judgment improve, and life can be taken care of oneself, continue and obeyed Chinese medicine composition of the present invention 3 months, all recover as before, follow up a case by regular visits to 1 year surplus, do not see recurrence.
5, Gong so-and-so, woman, 57 years old, peasant.
Told forgetful 2 years, hypomnesis, absent minded, timid susceptible to fright, vexed uneasiness, it is disintoxicated to sleep night, sticks with paste when clear during mind, and the sight anxiety is given an irrelevant answer, computing power forfeiture, thirst and drinking, constipation, the dizzy soreness of waist, emaciated physique.Red tongue, tongue is few, thready pulse.
Took Chinese medicine composition of the present invention 2 months, memory increases, and mind is clear, god's peace of sleeping surely, can answer simple problem, the dizzy soreness of waist subtracts, thirstyly removes, and is convenient to both as usual, recover the units computing power, continue and obeyed Chinese medicine composition of the present invention 3 months, the state of an illness takes a turn for the better gradually, is emotionally stable, memory, faculty of understanding, judgment significantly improve, and life can be taken care of oneself, and the clothes Chinese medicine composition of the present invention that continues is surplus March, mind is more preceding more clear, and is in high spirits, has rosy cheeks, the food of sleeping is all good, and question and answer are kept to the point, and life is normal.
6, the king so-and-so, man, 21 years old, student.
Because of tumbling down injures head, once went into a coma at that time two, three minutes before 3 years.The head of wounding again when playing football before 2 years, dizzy all day so far expanding, memory obviously fails, the thinking logic confusion, language performance is incomplete, forgets after the preceding note, and body constitution is not good, and lassitude has a strong impact on studying and living.
Took Chinese medicine composition of the present invention 1 month, hypomnesis before makes moderate progress, and dizzy feeling of fullness in the head disappears substantially, spirit is gradually shaken, and continues and obeys Chinese medicine composition of the present invention 2 months, and memory significantly promotes, the more preceding improvement of body constitution, symptom is greatly taken on a new look, and continues and obeys Chinese medicine composition of the present invention 3 months, and thinking of logic is clear, language performance is clear, in high spirits, conscious having good memory in ancient times lived and learnt to feel more light.
7, Huang, woman, 45 years old, shop assistant.
The various symptoms that cerebral blood supply insufficiency appears in the beginning of the year take medicine after making a definite diagnosis, but memory go down obviously constantly always, the saying diction is put upside down, apathetic expression, bradykinesia, uneasy sleeping at night, sometimes relatives all are not familiar with at one's side, the door is always gone to the wrong way in the stroll of oneself going out, and can't take care of oneself, and tongue fur is dark, tongue is white, and arteries and veins is dazzled carefully.
Took Chinese medicine composition of the present invention 1 month, memory promotes to some extent, and spirit is improved, the sleep amelioration, continue and obeyed Chinese medicine composition of the present invention 1 month, the state of an illness takes a turn for the better gradually, and memory before significantly improves, and life can be taken care of oneself, continue and obeyed Chinese medicine composition of the present invention 3 months, question and answer are kept to the point, and all recover as before, the unit's of getting back to operate as normal.
8, Liu, man, 44 years old, cadre.
Carbon monoxide poisoning has been remained unconscious when its relatives find, and hands spreads the enuresis, and that exhales should not.Revive after suddenly giving certain hospital to rescue.Dizziness headache after waking up, suffocating in the heart, dysphoria, the tending to vomit of feeling sick, the whole body is weak, hypomnesis, absentminded continues the symptomatic treatment a few days, and all diseases disappear substantially and leave hospital.But hypomnesis is obvious afterwards, forgets appointment or colleague's name sometimes, the thinking logic confusion, and language performance is incomplete, thing before 2 years forgets substantially, and just word does not just have impression, and body constitution is relatively poor, mild in the past, present hot-tempered impermanence, the recuperation of being in of having asked for leave.
Took Chinese medicine composition of the present invention 1 month, hypomnesis improves, and logic is clear gradually, emotion takes a turn for the better, and continues and obeys Chinese medicine composition of the present invention 2 months, and memory before significantly improves, memory far away recovers gradually, is emotionally stable, and the state of an illness is greatly taken on a new look, continue and obeyed Chinese medicine composition of the present invention 5 months, thinking is clear, and question and answer are kept to the point, body constitution is preferable, normal fully, spirit and energy are better than habitually in the past, resume work.
Five, therapeutic outcome:
In the 49 routine cases of being accepted for medical treatment,, wherein cure 15 examples through treatment in 10 months, produce effects 13 examples, effective 17 examples, invalid 4 examples, total effective rate reaches 91%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment hypomnesis patient.
Claims (6)
1. Chinese medicinal capsule agent for the treatment of hypomnesis, it is characterized in that: take by weighing each raw material: 100 parts of Fructus Alpiniae Oxyphyllae by following weight portion, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii grind into after each component of above-mentioned weight mixed and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
2. Chinese medicine granules for the treatment of hypomnesis, it is characterized in that: take by weighing each raw material: 100 parts of Fructus Alpiniae Oxyphyllae by following weight portion, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii, each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
3. Chinese medicinal tablet for the treatment of hypomnesis, it is characterized in that: take by weighing each raw material: 100 parts of Fructus Alpiniae Oxyphyllae according to following weight portion, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii, each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
4. medicine pill for the treatment of hypomnesis, it is characterized in that: take by weighing each raw material: 100 parts of Fructus Alpiniae Oxyphyllae according to following weight portion, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii, each raw material of above-mentioned weight portion is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
5. Chinese medicine oral liquid for the treatment of hypomnesis, it is characterized in that: take by weighing each raw material: 100 parts of Fructus Alpiniae Oxyphyllae according to following weight portion, 120 parts of Rhizoma Acori Graminei, 100 parts of Radix Codonopsis, 50 parts of Radix Angelicae Sinensis, 100 parts of Radix Astragali, 10 parts of Radix Ginsengs, 100 parts of the Radix Paeoniae Albas, 30 parts of Radix Paeoniae Rubra, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Dioscoreaes, 100 parts of Massa Medicata Fermentata, 100 parts of Fructus Hordei Germinatus (parched to brown)s, 150 parts of Cortex Magnoliae Officinalis, 30 parts of Flos Chrysanthemis, 100 parts of Radix Puerariaes, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Semen Euryaless, 150 parts of Pericarpium Citri Reticulataes, 100 parts of Rhizoma Cyperi, 30 parts of Radix Rehmanniae Preparata, 50 parts of Herba Leonuris, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 20 parts of Cortex Albiziaes, 20 parts of Radix Polygalaes, 30 parts of Styrax, 10 parts of Cordyceps, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of Carapax Trionycis (processed), 15 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Herba Cistanches, 20 parts of Rhizoma Cibotii, 10 parts of Radix Panacis Quinquefoliis, 30 parts of Semen Arecae Preparetas, 30 parts of Fructus Psoraleaes, 30 parts of the Cortexs Eucommiae, 20 parts of Radix Dipsacis, 30 parts of Radix Polygoni Multiflori, 10 parts on Flos Carthami, 50 parts of Radix Adenophorae (Radix Glehniae), 20 parts in Lignum Santali Albi, 20 parts of Benzoinumes, 50 parts of the Radixs Linderae, 30 parts in Rhizoma Curcumae Longae, 30 parts of Semen Platycladi, 10 parts of Camphoras, 10 parts of Borneolum Syntheticums, 30 parts of Cortex Phellodendris, 20 parts of Radix Et Rhizoma Rhei, 20 parts of Herba Pogostemoniss, 50 parts of the Radix Aucklandiae, 40 parts of Radix Curcumaes, 30 parts of Fructus Lycii, each raw material of above-mentioned weight portion is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into the concentration of regulation, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
6. the application of any described Chinese medicine composition of claim 1～5 in preparation treatment hypomnesis medicine.
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