CN103734853B - The beverage that a kind of Improving memory increases intelligence - Google Patents
The beverage that a kind of Improving memory increases intelligence Download PDFInfo
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- CN103734853B CN103734853B CN201410019232.1A CN201410019232A CN103734853B CN 103734853 B CN103734853 B CN 103734853B CN 201410019232 A CN201410019232 A CN 201410019232A CN 103734853 B CN103734853 B CN 103734853B
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- 235000013361 beverage Nutrition 0.000 title claims abstract description 40
- 241000405414 Rehmannia Species 0.000 claims abstract description 43
- 244000001632 Acorus gramineus Species 0.000 claims abstract description 19
- 235000013073 Acorus gramineus Nutrition 0.000 claims abstract description 19
- 241000208688 Eucommia Species 0.000 claims abstract description 19
- 241000208966 Polygala Species 0.000 claims abstract description 19
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 18
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 48
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- 239000007788 liquid Substances 0.000 claims description 16
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- 239000003153 chemical reaction reagent Substances 0.000 claims description 8
- 239000006071 cream Substances 0.000 claims description 8
- 238000000605 extraction Methods 0.000 claims description 8
- 239000000706 filtrate Substances 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 8
- 239000006228 supernatant Substances 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 239000012467 final product Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
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- 238000012360 testing method Methods 0.000 description 11
- CMVHOLZLFLESKY-UHFFFAOYSA-N Anisodine Natural products CN1C2CC(CC1C3OC23)C(=O)OC(O)(CO)c4ccccc4 CMVHOLZLFLESKY-UHFFFAOYSA-N 0.000 description 10
- JEJREKXHLFEVHN-QDXGGTILSA-N anisodine Chemical compound C1([C@](O)(CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 JEJREKXHLFEVHN-QDXGGTILSA-N 0.000 description 10
- 238000003304 gavage Methods 0.000 description 10
- 108010011485 Aspartame Proteins 0.000 description 7
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 7
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- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
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- 230000036541 health Effects 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
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- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
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- 230000009189 diving Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
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- 235000013305 food Nutrition 0.000 description 1
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- 235000012907 honey Nutrition 0.000 description 1
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- 239000011726 vitamin B6 Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates to the beverage that a kind of Improving memory increases intelligence, it is characterized in that, prepare with the raw material of following weight proportion: fructus alpiniae oxyphyllae 3-12g, safflower 3-9g, polygala root 3-6g, grass-leaved sweetflag 3-12g, fresh rehmannia root 30-90g, bark of eucommia 3-9g.Beverage vessel of the present invention is improved the effect of memory-enhancing effect intelligence.
Description
Technical field
The present invention relates to beverage, particularly a kind of Improving memory, the beverage increased intelligence, belong to Medicines and Health Product technical field.
Background technology
Memory is a kind of mental process, is the impression of people to the thing living through, occurred, and preserves in the brain, and extract when needed, recall out through processing.
Adult's memory increases with the age and changes, and this is the change of a kind of physiological, is a kind of normal aging of memory.The sensation that a lot of the elderly has memory to be not so good as at an early age, but also some people was by eight or nine ten years old, and brain function is still in good working order.Science brain tonic delays brain aging to the elderly, strengthens memory most important.
Decrease of memory is not the patent of the elderly, causes the reason of decrease of memory a lot, not enough comprising extended sleep, lack exercise, lack fresh air, and tobacco and wine are excessive.Long-term anxiety is excessively melancholy, psychological pressure is excessive also can lessen one's memory.In actual life, usually can see people gently of many people's ages, the decrease of memory problems such as thing is not remembered in main suit's existence, forgetful.Have report, pressure is the key factor causing people's Impairment of Memory.The performance of people in recall tests be often under high stress is poor.If a people bears high stress 3-5, his memory just may fail.
Failure of memory belongs to the sick category such as the traditional Chinese medical science " forgetful ", " happiness is forgotten ", " forgetting ", " forgetting well " more, is the important symptom of Aging.Comprehensive ancient medicine is to the understanding of this disease, and failure of memory is that a pathology relates to multiple internal organs, again the turbid closely-related comprehensive complicated illness with qi and blood phlegm.Its sick position, mainly at the heart, spleen, kidney, has with liver, brain, lung and necessarily contacts.Its characteristic of disease have actual situation point, mostly empty person is to have a guilty conscience, suffer from a deficiency of the kidney, insufficiency of the spleen, qi and blood declines less not enough with brains; Reality person mostly is that hemostasis, phlegm are turbid, the turbid fire of irritability stasis, the heart channel of Hang-Shaoyin.Its cause of disease is in the majority with internal injury, depression of QI, in blinded judgment, worry beyond measure, " ask hope farsighted, be willing to unsuccessful ", insufficiency of natural endowment etc. all can cause this disease to occur.Its interpretation of the cause, onset and process of an illness is comparatively complicated, not normal closely related with function of five internal organs, and by the differentiation of many internal organs, finally cause heresy to disturb the mind or the foster two ends of mind mistake, the loss of heart spleen kidney is the pathologic basis of its inherence, and phlegm-turbidity and blood stasis blood hoodwinks the key that key is clearly its morbidity.
In today that population is day by day aging, its incidence of disease has the trend increased year by year, and effective methods for the treatment of is all being sought energetically by a lot of research institution.Chinese patent drug in the market for Improving memory is used for kidney tonifying, tonifying Qi, and by improving physical condition, indirect treatment of building up health, exists effect slow, the defect of weak curative effect.
Summary of the invention
The object of this invention is to provide the beverage that a kind of Improving memory increases intelligence.
The raw material of beverage of the present invention through processing and other food and medicine additives be mixed with into can be oral beverage, additive comprises: flavouring, anticorrisive agent, as sucrose, honey, aspartame nipalgin.
The beverage that a kind of Improving memory of the present invention increases intelligence, is characterized in that, the raw material preparation with comprising following weight proportion: fructus alpiniae oxyphyllae 3-12g, safflower 3-9g, polygala root 3-6g, grass-leaved sweetflag 3-12g, fresh rehmannia root 30-90g, bark of eucommia 3-9g.
The beverage that the above-mentioned a kind of Improving memory of the present invention increases intelligence, is optimized for the raw material preparation with comprising following weight proportion: fructus alpiniae oxyphyllae 6g, safflower 6g, polygala root 3g, grass-leaved sweetflag 6g, fresh rehmannia root 45g, bark of eucommia 3g further.
The beverage that the above-mentioned a kind of Improving memory of the present invention increases intelligence, the fresh rehmannia root in raw material, can not replace with radix rehmanniae recen or prepared rhizome of rehmannia, if the curative effect of being replaced, reduce.
More than consist of adult's taking dose of 1-2 days, can increase according to corresponding ratio when producing or reduce, as large-scale production can by kilogram or in units of ton, but the crude drug weight proportion constant rate between each component, the taking dose of being grown up a day is constant.
Beverage of the present invention is prepared by the following method:
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 1.5 times of water gagings, stir extraction 4 hours, extracting liquid filtering at 0 ~ 10 DEG C, centrifugal, obtains fresh rehmannia root extract.
B (), by fructus alpiniae oxyphyllae, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 6-8 times of water gaging, decoct 1-2 hour, second time adds 4-6 times of water gaging, decocts 1-2 hour; Merge twice decocting liquid, filter, the clear cream that concentrated filtrate extremely weighs with medicinal material etc.;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract;
D (), by fresh rehmannia root extract, alcohol extract merges, and adds or does not add flavouring, anticorrisive agent, stirring and dissolving, then adding suitable quantity of water, mixing, filters, obtain beverage.
Beverage vessel of the present invention is improved the effect of memory-enhancing effect intelligence.
For a better understanding of the present invention, beneficial effect of the present invention is set forth further below by way of test example.Test example is intended to further illustrate effect of the present invention below, but not restriction of the present invention.
Test the effect that a beverage memory of the present invention obviously goes down
Lee, female, 26 years old, nearly 1 year excessively a tax on one's mind because of appendix, and memory obviously goes down, dizzy insomnia.Existing disease: forgetful, forgetful, night has difficulty in going to sleep, dreaminess after sleeping, easily frightened easily awake, dizzy palpitaition, dry throat, the soreness of waist, takes the beverage that Improving memory of the present invention increases intelligence, every day 2 bottles, after 10 days, sleeps gradually good, not forgetful; After 20 days, memory is cumulative, can memorize foreign language, and only dizzy, palpitaition disappears; After 40 days, memory is significantly better than before disease, and spirit is refreshing, and body power increases.To be taken an examination by Master degree candidate smoothly then.
Test the impact test of two beverages of the present invention on anisodine induced mice memory damage
1, method adopts step dow n test, and during training, mouse is put into respectively reflective box endoadaptation 3 min, be then energized immediately, after animal is shocked by electricity, diving tower is jumped onto in its normal reaction, escapes electric shock.Animal skip on copper grid or biped contact copper grid time be subject to electric shock for mistake.Training 5min like this, and misregistration number of times.Retest after 24h, the errors number in record 5min.
2, mouse 50 is got in test, is divided into 5 groups at random, often organizes 10.1. being Normal group, is 2. Anisodine model group, 3.-be 5. respectively beverage group prepared by embodiment of the present invention 1-3.1., 2. organize and gavage physiological saline 10ml/kg every day, divide and gavage for 2 times.3.-and 5. organize the beverage 10ml/kg gavaging embodiment of the present invention 1-3 respectively and prepare, divide and gavage for 2 times.Continuous 7d.1h after last administration, 1. group gavages normal saline, 2.-5. gavage anisodine 10 mg/kg.After administration, 10 min start training, test Memory result after 24h.
3, result beverage of the present invention can make mouse wrong times obviously reduce, and shows that beverage of the present invention improves significantly to anisodine induced mice memory damage.In table 1.
Table 1 beverage of the present invention is on the impact (n=10 ,-x ± s) of anisodine induced mice memory damage
| Group | 5min errors number |
| Control group | 0.65±0.81 |
| Model group | 2.06±0.63 |
| Embodiment 1 group | 0.80±0.13 |
| Embodiment 2 groups | 0.90±0.09 |
| Embodiment 3 groups | 0.80±0.46 |
Test three beverage fresh rehmannia roots of the present invention and replace with the impact test of radix rehmanniae recen on anisodine induced mice memory damage
1, method adopts above-mentioned step dow n test, gets mouse 60, is divided into 6 groups at random, often organizes 10.1. being Normal group, is 2. Anisodine model group, 3. for fresh rehmannia root replaces with beverage group prepared by radix rehmanniae recen, 4.-be 6. respectively beverage group prepared by embodiment of the present invention 1-3.1., 2. organize and gavage physiological saline 10ml/kg every day, point 2 tank clothes.3. gavage fresh rehmannia root every day and replace with beverage 10ml/kg prepared by radix rehmanniae recen, point 2 tanks clothes.4.-6. gavage beverage 10ml/kg prepared by embodiment of the present invention 1-3 respectively, point 2 tanks clothes.Continuous 7d.1h after last administration, 1. gavages normal saline, 2.-6. gavage anisodine 10mg/kg.After administration, 10min starts training, tests Memory result after 24h.
2, result beverage of the present invention can make mouse wrong times obviously reduce, and shows that beverage of the present invention improves significantly to anisodine induced mice memory damage, and the beverage that fresh rehmannia root is prepared after replacing with radix rehmanniae recen, effect decreases.In table 2.
Table 2 beverage fresh rehmannia root of the present invention replaces with impact test (n=10 ,-x ± s) of radix rehmanniae recen on anisodine induced mice memory damage
| Group | 5min errors number |
| Control group | 0.70±0.81 |
| Model group | 1.90±0.63 |
| Fresh rehmannia root replaces with radix rehmanniae recen group | 1.30±0.69 |
| Embodiment 1 group | 0.80±0.57 |
| Embodiment 2 groups | 0.90±0.69 |
| Embodiment 3 groups | 0.80±0.52 |
Embodiment 1
Take fructus alpiniae oxyphyllae 60g, safflower 40g, polygala root 40g, grass-leaved sweetflag 30g, fresh rehmannia root 600g, bark of eucommia 60g, aethyl parabenum 2.5g aspartame 0.5g.
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 900ml water, stir extraction 4 hours, extracting liquid filtering at 4 DEG C, centrifugal, obtains fresh rehmannia root extract.
B (), by fructus alpiniae oxyphyllae, the fruit of Chinese wolfberry, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 2000ml water, decocts 2 hours, second time adds 1500 water, decocts 2 hours, merges twice decocting liquid, and filter, concentrated filtrate obtains cream 170g clearly;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract 170g;
D (), by fresh rehmannia root extract, alcohol extract merges, add raw plain B1, vitamin B6 and aethyl parabenum, aspartame etc., stirring and dissolving, is added to 5000ml, and mixing is filtered, is distributed into 20 bottles, within 1st, drinks 1-2 bottle.Obtain beverage.
Embodiment 2
Take fructus alpiniae oxyphyllae 40g, safflower 20g, polygala root 20g, grass-leaved sweetflag 60g, fresh rehmannia root 300g, bark of eucommia 30g, aethyl parabenum 5g, aspartame 0.3g.
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 1.5 times of water gagings, stir extraction 4 hours, extracting liquid filtering at 10 DEG C, centrifugal, obtains fresh rehmannia root extract.
B (), by fructus alpiniae oxyphyllae, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 6 times of water gagings, decocts 1 hour, second time adds 4 times of water gagings, decocts 1 hour, merges twice decocting liquid, and filter, concentrated filtrate obtains cream 140g clearly;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract 140g;
D (), by fresh rehmannia root extract, alcohol extract merges, and adds aethyl parabenum, aspartame etc., stirring and dissolving, is added to 5000ml, mixing, filters, be distributed into 20 bottles, within 1st, drink 1-2 bottle.Obtain beverage.
Embodiment 3
Take fructus alpiniae oxyphyllae 50g, safflower 30g, polygala root 30g, grass-leaved sweetflag 50g, fresh rehmannia root 900g, bark of eucommia 90g, aethyl parabenum 2.5g, aspartame 0.3g.
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 1.5 times of water gagings, stir extraction 4 hours, extracting liquid filtering at 0 DEG C, centrifugal, obtains fresh rehmannia root extract;
B (), by the fructus alpiniae oxyphyllae of described weight proportion, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 8 times of water gagings, decocts 2 hours, second time adds 4 times of water gagings, decocts 1 hour.Merge twice decocting liquid, filter, concentrated filtrate obtains cream 160g clearly;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract 160;
D (), by fresh rehmannia root extract, alcohol extract merges, and adds aethyl parabenum, aspartame etc., stirring and dissolving, is added to 5000ml, mixing, filters, be distributed into 20 bottles, within 1st, drink 1-2 bottle.Obtain beverage.
Embodiment 4
Take fructus alpiniae oxyphyllae 120g, safflower 90g, polygala root 60g, grass-leaved sweetflag 120g, fresh rehmannia root 900g, bark of eucommia 90g.
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 1.5 times of water gagings, stir extraction 4 hours, extracting liquid filtering at 5 DEG C, centrifugal, obtains fresh rehmannia root extract;
B (), by the fructus alpiniae oxyphyllae of described weight proportion, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 8 times of water gagings, decocts 2 hours, second time adds 4 times of water gagings, decocts 1 hour.Merge twice decocting liquid, filter, concentrated filtrate obtains the clear cream of proportion 1.2;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract;
D (), by fresh rehmannia root extract, alcohol extract merges, and is added to 5000ml, mixing, filters, be distributed into 20 bottles, within 1st, drink 1-2 bottle.Obtain beverage.
Embodiment 5
Take fructus alpiniae oxyphyllae 60g, safflower 60g, polygala root 30g, grass-leaved sweetflag 60g, fresh rehmannia root 450g, bark of eucommia 30g.
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 1.5 times of water gagings, stir extraction 4 hours, extracting liquid filtering at 5 DEG C, centrifugal, obtains fresh rehmannia root extract;
B (), by the fructus alpiniae oxyphyllae of described weight proportion, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 8 times of water gagings, decocts 2 hours, second time adds 4 times of water gagings, decocts 1 hour.Merge twice decocting liquid, filter, concentrated filtrate obtains the clear cream of proportion 1.5;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract;
D (), by fresh rehmannia root extract, alcohol extract merges, and is added to 5000ml, mixing, filters, be distributed into 20 bottles, within 1st, drink 1-2 bottle.Obtain beverage.
Embodiment 6
Take fructus alpiniae oxyphyllae 30g, safflower 30g, polygala root 30g, grass-leaved sweetflag 30g, fresh rehmannia root 300g, bark of eucommia 30g.
A (), by fresh rehmannia root fragmentation (granularity 6mm), adds 1.5 times of water gagings, stir extraction 4 hours, extracting liquid filtering at 5 DEG C, centrifugal, obtains fresh rehmannia root extract;
B (), by the fructus alpiniae oxyphyllae of described weight proportion, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 8 times of water gagings, decocts 2 hours, second time adds 4 times of water gagings, decocts 1 hour.Merge twice decocting liquid, filter, concentrated filtrate obtains the clear cream of proportion 1.2;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract;
D (), by fresh rehmannia root extract, alcohol extract merges, and is added to 5000ml, mixing, filters, be distributed into 20 bottles, within 1st, drink 1-2 bottle.Obtain beverage.
Claims (2)
1. Improving memory increases intelligence a preparation method for beverage, it is characterized in that preparing with the raw material of following weight proportion: fructus alpiniae oxyphyllae 3-12g, safflower 3-9g, polygala root 3-6g, grass-leaved sweetflag 3-12g, fresh rehmannia root 30-90g, bark of eucommia 3-9g;
Wherein preparation method is:
A fresh rehmannia root is crushed to granularity by () is 6mm, adds 1.5 times of water gagings, stirs extraction 4 hours, extracting liquid filtering at 0 ~ 10 DEG C, centrifugal, obtains fresh rehmannia root extract;
B (), by fructus alpiniae oxyphyllae, safflower, polygala root, the bark of eucommia and grass-leaved sweetflag boiling twice, first time adds 6-8 times of water gaging, decoct 1-2 hour, second time adds 4-6 times of water gaging, decoct 1-2 hour: merge twice decocting liquid, filter, the clear cream that concentrated filtrate extremely weighs with medicinal material etc.;
C () qinghuo reagent adds ethanol to 70%, place 24 hours, get supernatant in 4 DEG C, reclaims ethanol, obtains alcohol extract;
D (), by fresh rehmannia root extract, alcohol extract merges, and adds or does not add flavouring, anticorrisive agent, stirring and dissolving, then adding suitable quantity of water, mixing, filters, to obtain final product.
2. a kind of Improving memory according to claim 1 increases intelligence the preparation method of beverage, it is characterized in that preparing with the raw material of following weight proportion: fructus alpiniae oxyphyllae 6g, safflower 6g, polygala root 3g, grass-leaved sweetflag 6g, fresh rehmannia root 45g, bark of eucommia 3g.
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| CN104587270A (en) * | 2015-02-11 | 2015-05-06 | 郭如英 | Medicine for treating mental retardation of infants and young children and preparation method thereof |
| CN110477159A (en) * | 2019-09-12 | 2019-11-22 | 三亚市林业科学研究院 | A kind of preparation method of intelligence development jasmine tea and its intelligence development jasmine tea of preparation |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113153A (en) * | 1994-06-04 | 1995-12-13 | 吕云宏 | Oral tonic for promoting children's intelligence |
| CN1220151A (en) * | 1997-12-18 | 1999-06-23 | 庄清宝 | Brain invigorating pill |
| CN1843225A (en) * | 2006-05-12 | 2006-10-11 | 宋谋友 | Healthcare drink and its preparation method |
| CN101757573A (en) * | 2010-01-19 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating memory loss and preparation method thereof |
| CN102366005A (en) * | 2011-06-22 | 2012-03-07 | 王学文 | Intelligence-promoting and brain-invigorating healthcare tea |
| CN102772724A (en) * | 2011-05-13 | 2012-11-14 | 冯月花 | Intelligence-benefiting brain-nourishing polysaccharide tablet (pill) for children |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100530211B1 (en) * | 2003-12-29 | 2005-11-22 | 양순길 | Healthy and functional food composition for the improvement of the studying capability and its process |
| KR101458823B1 (en) * | 2012-06-22 | 2014-11-07 | (주) 젠셀 | Healthy and functional food for improving concentration or growth by using fermented natural products and the manufacturing method |
-
2014
- 2014-01-16 CN CN201410019232.1A patent/CN103734853B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113153A (en) * | 1994-06-04 | 1995-12-13 | 吕云宏 | Oral tonic for promoting children's intelligence |
| CN1220151A (en) * | 1997-12-18 | 1999-06-23 | 庄清宝 | Brain invigorating pill |
| CN1843225A (en) * | 2006-05-12 | 2006-10-11 | 宋谋友 | Healthcare drink and its preparation method |
| CN101757573A (en) * | 2010-01-19 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating memory loss and preparation method thereof |
| CN102772724A (en) * | 2011-05-13 | 2012-11-14 | 冯月花 | Intelligence-benefiting brain-nourishing polysaccharide tablet (pill) for children |
| CN102366005A (en) * | 2011-06-22 | 2012-03-07 | 王学文 | Intelligence-promoting and brain-invigorating healthcare tea |
Non-Patent Citations (1)
| Title |
|---|
| 张志健,等.杜仲叶饮料加工工艺研究.《食品科技》.2007,(第3期),第183-186页. * |
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