CN101757373A - Medicament for treating gastropathy characterized by hypochlorhydria and preparation method thereof - Google Patents

Medicament for treating gastropathy characterized by hypochlorhydria and preparation method thereof Download PDF

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CN101757373A
CN101757373A CN200910250117A CN200910250117A CN101757373A CN 101757373 A CN101757373 A CN 101757373A CN 200910250117 A CN200910250117 A CN 200910250117A CN 200910250117 A CN200910250117 A CN 200910250117A CN 101757373 A CN101757373 A CN 101757373A
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fructus
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liver
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gastropathy
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孙喜灵
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Abstract

The invention discloses a medicament for treating gastropathy characterized by hypochrhydria and a preparation method thereof. The medicament belongs to a pure traditional Chinese medicine preparation prepared from white paeony root, hawthorn, pawpaw, fructus citri, smoked plum, medicinal cyathula root, semen phaseoli, Chinese magnoliavine fruit, cornus fruit, Chinese yam and liquorice. The invention provides the traditional Chinese medicine preparation which can achieve obvious treatment effect on gastropathy of astringent and bitter taste (bitter vomit), yellow vomit, (basic) heartburn and the like caused by deficiency of liver qi by using a method of supplementing liver qi and strengthening catharsis.

Description

A kind of gastric acid for the treatment of lacks medicine for the gastropathy of feature and preparation method thereof less
It is few or lack medicine for the gastropathy of feature that technical field the present invention relates to a kind of gastric acid for the treatment of, it is pure Chinese herbal medicine, specifically a kind of is method with tonifying liver gas, strong catharsis, and that the treatment deficiency of liver-QI causes is mouthful puckery, bitter taste (or telling hardship), tell the pharmaceutical preparation of diseases such as Huang, (alkalescence) be heartburn.The invention still further relates to the preparation method of this medicine.
Background technology gastric acid is few or lack for the gastropathy of feature and mainly caused by deficiency of the liver, its symptom for mouthful puckery, bitter taste (or telling hardship), to tell Huang, (alkalescence) heartburn etc., existing treatment gastric acid is few or shortage is very few for the Chinese patent medicine of the gastropathy of feature, and curative effect is not remarkable, and cure rate is low.
Summary of the invention the present invention is intended to improve above-mentioned deficiency, provides a kind of gastric acid for the treatment of few or lack medicine for the gastropathy of feature and preparation method thereof.By being method with tonifying liver gas, strong catharsis, that the treatment deficiency of liver-QI causes is mouthful puckery, bitter taste (or telling hardship), tell diseases such as Huang, (alkalescence) be heartburn.
In order to achieve the above object, the present invention realizes like this.
A kind of gastric acid for the treatment of lacks medicine for the gastropathy of feature less, and it is composed of the following components, Radix Paeoniae Alba 1-100 part, Fructus Crataegi 1-100 part, Fructus Chaenomelis 1-100 part, Fructus Citri 1-100 part, Fructus Mume 1-100 part, Radix Cyathulae 1-170 part, Semen Phaseoli 1-170 part, Fructus Schisandrae Chinensis 1-330 part, Fructus Corni 1-100 part, Fructus Gardeniae 1-100 part, Rhizoma Dioscoreae 1-100 part, Radix Glycyrrhizae 1-100 part; Described part refers to weight portion.
More the set of dispense ratio of You Huaing is: 4 parts of the Radix Paeoniae Albas, 4 parts of Fructus Crataegis, 9 parts of Fructus Chaenomeliss, 5 parts of Fructus Citris, 25 parts of Fructus Mumes, 150 parts of Radix Cyathulaes, 150 parts of Semen Phaseolis, 300 parts of Fructus Schisandrae Chinensis, 30 parts of Fructus Corni, 3 parts of Fructus Gardeniaes, 3 parts of Rhizoma Dioscoreaes, 3 parts in Radix Glycyrrhizae.
Good effect of the present invention is: to be slightly cold, to return the liver spleen channel be principal agent to Radix Paeoniae Alba picric acid in the side, its sour in taste acting on the liver energy tonifying liver gas, strong catharsis, the function of recovery liver controlling conveyance and dispersion, burnt mechanism of qi hinge running is unimpeded in the maintenance, then spleen can rise, stomach can fall, and bile can the row of descending and returned not; Its hardship can be rushed down, under the bilious flux of overflow; Its cold controlling heat, the strongly fragrant and heat of heat-transformation of bile of system overflow.The sweet tepor of Crataegolic acid, return the taste Liver Channel, its flavor sour in taste acting on the liver can tonifying liver gas, strong catharsis, is the key medicine of the greasy meat stagnation that disappears, remove greasy carnivorous regular meeting bring out or increase the weight of to return on the bile because of; The cydonic acid temperature, return liver spleen channel, its sour in the mouth can go into liver and tonifying liver gas, strong catharsis, again can the stomach function regulating removing dampness and control and tell; The hot little picric acid temperature of Fructus Citri, return liver spleen lung meridian, its flavor sour in taste acting on the liver tonifying liver gas, strong catharsis, again can depressed liver-energy dispersing and QI regulating and in, transfer smooth in the hinge of burnt mechanism of qi; Last three medicines are assisted principal agent, are ministerial drug altogether.The Liver and kidney warp is put down, returned to the Radix Cyathulae picric acid, its flavor sour in taste acting on the liver and tonifying liver gas, strong catharsis, and merit is arrogated to oneself bitter diarrhea and is fallen again, can conducting blood to flow downwards, to fall the fire of inflammation, for returning the product that amass in the stomach fire-transformation on the bile of dispelling; Liver spleen lung large intestine channel is put down, is returned in Fructus Mume acid, and its flavor sour in taste acting on the liver and tonifying liver gas, strong catharsis again can promoting the production of body fluid to quench thirst; The sweet acid of Semen Phaseoli is flat, GUIXIN small intestine meridian, energy dampness removing jaundice eliminating; The trimethyl gallic acid temperature, return lung kidney heart channel, but promoting the production of body fluid to quench thirst, again can replenishing the kidney(water)to nourish the liver(wood), can also hold back Jin Fumu, mind calming peace wood; Fructus Corni acid little puckery, return the Liver and kidney warp, its flavor sour in taste acting on the liver and tonifying liver gas, strong catharsis again can replenishing the kidney(water)to nourish the liver(wood); Last five medicines help the power of the monarch and his subjects' medicine, are adjuvant drug altogether.It is the principle of " disease of husband liver, using drugs with sour taste for invigoration " that above-mentioned nine flavor medicines embody, and " helping with burnt bitter " selects Fructus Gardeniae, its bitter cold, GUIXIN lung stomach tri-jiao channel, and both fire of the heat of three warmers clearly again can eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice; " medicine of using sweet drugs for tonifying is transferred it " selects Rhizoma Dioscoreae, and it is sweet puts down, returns spleen lung kidney channel, supplementing QI and nourishing YIN; Sweet flat, the GUIXIN lung taste warp of Radix Glycyrrhizae, coordinating the actions of various ingredients in a prescription.More than all medicine compatibilities, side card is harmonious, medicine disease correspondence, curative effect are directly and significantly.
The specific embodiment further specifies the present invention in order to understand better and to implement below in conjunction with embodiment.
[preparation example]
Preparation example one
The Radix Paeoniae Alba 4 grams, Fructus Crataegi 4 grams, Fructus Chaenomelis 9 grams, Fructus Citri 5 grams, Fructus Mume 25 grams, Radix Cyathulae 150 grams, Semen Phaseoli 150 grams, Fructus Schisandrae Chinensis 300 grams, Fructus Corni 30 grams, Fructus Gardeniae 3 grams, Rhizoma Dioscoreae 3 grams, Radix Glycyrrhizae 3 grams.
Method for making: above-mentioned pulverizing medicinal materials is become 100 order fine powders, and abundant mix homogeneously is by the specification of every gram 10 balls, the general ball of making.60 ℃ of oven dry, packing promptly.
Preparation example two
The Radix Paeoniae Alba 1 gram, Fructus Crataegi 1 gram, Fructus Chaenomelis 1 gram, Fructus Citri 1 gram, Fructus Mume 100 grams, Radix Cyathulae 170 grams, Semen Phaseoli 170 grams, Fructus Schisandrae Chinensis 330 grams, Fructus Corni 100 grams, Fructus Gardeniae 1 gram, Rhizoma Dioscoreae 1 gram, Radix Glycyrrhizae 1 gram.
Method for making is with example one.
Preparation example three
The Radix Paeoniae Alba 50 grams, Fructus Crataegi 50 grams, Fructus Chaenomelis 50 grams, Fructus Citri 50 grams, Fructus Mume 50 grams, Radix Cyathulae 85 grams, Semen Phaseoli 85 grams, Fructus Schisandrae Chinensis 165 grams, Fructus Corni 50 grams, Fructus Gardeniae 50 grams, Rhizoma Dioscoreae 50 grams, Radix Glycyrrhizae 50 grams.
Method for making is with example one.
Preparation example four
The Radix Paeoniae Alba 100 grams, Fructus Crataegi 100 grams, Fructus Chaenomelis 100 grams, Fructus Citri 100 grams, Fructus Mume 1 gram, Radix Cyathulae 1 gram, Semen Phaseoli 1 gram, Fructus Schisandrae Chinensis 1 gram, Fructus Corni 1 gram, Fructus Gardeniae 100 grams, Rhizoma Dioscoreae 100 grams, Radix Glycyrrhizae 100 grams.
Method for making is with example one.
[character] this product is the watered pill of yellowish-brown to pitchy; Feeble QI, mildly bitter flavor.
This invention medicine that preparation adopts is not violated " eighteen incompatible medicaments ", " nineteen medicaments of mutual restraint ", mutual compatibility, no mutual inhibition reverse situation.Untoward reaction is not found in clinical practice.
Mouthful puckery, the bitter taste (or telling hardship) that causes with medicine of the present invention treatment deficiency of liver-QI, tell symptom 100 examples such as Huang, (alkalescence) be heartburn, and do contrast with 30 examples of Bifidobacterium capsule treatment.The result shows medicine group obvious effective rate 76% of the present invention, total effective rate 96%; Between matched group obvious effective rate 33.33%, 66.67%, two group of total effective rate relatively (P<0.01), significant difference is arranged.Medicine of the present invention all is better than Bifidobacterium capsule at aspects such as eliminating clinical symptoms.
1, clinical data; All case is long grace hospital outpatient of Yantai Laishan in August, 1 20099 July in 2008 and ward patient, be divided into test group 100 examples by the completely random principle with medicine oral medication of the present invention, with matched group 30 examples of Bifidobacterium capsule (the beautiful pearl pharmacy 070216 of beautiful pearl group) oral medication:
Table one case source
Figure G2009102501174D00041
Learn to handle by statistics, P>0.05 is so think two groups of cases there was no significant differences of originating.
Table two liang group patient tcm symptom situation relatively
Figure G2009102501174D00042
Learn by statistics and handle, the main tcm symptom of P>0.05, two group patient compares no significant difference.
Table three liang group patient TCM Syndrome Type situation relatively
Figure G2009102501174D00043
Learn by statistics and handle P>0.05, two-stage patient's pattern of syndrome distribution there was no significant difference.
2, Therapeutic Method: test group: oral medicine of the present invention, each 10 grams, every day three times, logotype 45 days was a course of treatment; Matched group: use Bifidobacterium capsule, oral each 0.1g, day three times, 45 days is a course of treatment.
3, therapeutic outcome, curative effect relatively has significant difference after treatment group and the treatment of control group.
The clinical experiment result: the medicine that the present invention makes is observed through clinical case, and it is half an hour after meal that this medicine is taken Best Times.Mouthful puckery, the bitter taste (or telling hardship) that can treat effectively that deficiency of liver-QI causes, tell symptom such as Huang, (alkalescence) be heartburn.

Claims (2)

  1. One kind to treat gastric acid few or lack medicine for the gastropathy of feature, it is characterized in that: it is composed of the following components: Radix Paeoniae Alba 1-100 part, Fructus Crataegi 1-100 part, Fructus Chaenomelis 1-100 part, Fructus Citri 1-100 part, Fructus Mume 1-100 part, Radix Cyathulae 1-170 part, Semen Phaseoli 1-170 part, Fructus Schisandrae Chinensis 1-330 part, Fructus Corni 1-100 part, Fructus Gardeniae 1-100 part, Rhizoma Dioscoreae 1-100 part, Radix Glycyrrhizae 1-100 part; Described part refers to weight portion.
  2. 2. few or lack medicine for the gastropathy of feature according to the described treatment gastric acid of claim 1, it is characterized in that: it is composed of the following components: 4 parts of the Radix Paeoniae Albas, 4 parts of Fructus Crataegis, 9 parts of Fructus Chaenomeliss, 5 parts of Fructus Citris, 25 parts of Fructus Mumes, 150 parts of Radix Cyathulaes, 150 parts of Semen Phaseolis, 300 parts of Fructus Schisandrae Chinensis, 30 parts of Fructus Corni, 3 parts of Fructus Gardeniaes, 3 parts of Rhizoma Dioscoreaes, 3 parts in Radix Glycyrrhizae.
CN200910250117A 2009-11-27 2009-11-27 Medicament for treating gastropathy characterized by hypochlorhydria and preparation method thereof Pending CN101757373A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102423395A (en) * 2011-12-13 2012-04-25 孙喜灵 Traditional Chinese medicine for treating achlorhydria
CN102526424A (en) * 2012-02-01 2012-07-04 孙喜灵 Traditional Chinese medicine for treating liver qi deficiency type stomach diseases
CN103356911A (en) * 2013-06-24 2013-10-23 华洪萍 Traditional Chinese medicine for treating achlorhydria

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102423395A (en) * 2011-12-13 2012-04-25 孙喜灵 Traditional Chinese medicine for treating achlorhydria
CN102526424A (en) * 2012-02-01 2012-07-04 孙喜灵 Traditional Chinese medicine for treating liver qi deficiency type stomach diseases
CN103356911A (en) * 2013-06-24 2013-10-23 华洪萍 Traditional Chinese medicine for treating achlorhydria

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Open date: 20100630