CN101732795A - Pacemaking generation device and control method thereof - Google Patents

Pacemaking generation device and control method thereof Download PDF

Info

Publication number
CN101732795A
CN101732795A CN200810217603A CN200810217603A CN101732795A CN 101732795 A CN101732795 A CN 101732795A CN 200810217603 A CN200810217603 A CN 200810217603A CN 200810217603 A CN200810217603 A CN 200810217603A CN 101732795 A CN101732795 A CN 101732795A
Authority
CN
China
Prior art keywords
impedance
voltage
current
pacemaking
output
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN200810217603A
Other languages
Chinese (zh)
Other versions
CN101732795B (en
Inventor
刘方
何博
邵安岑
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Mindray Bio Medical Electronics Co Ltd
Original Assignee
Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Mindray Bio Medical Electronics Co Ltd filed Critical Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority to CN 200810217603 priority Critical patent/CN101732795B/en
Publication of CN101732795A publication Critical patent/CN101732795A/en
Application granted granted Critical
Publication of CN101732795B publication Critical patent/CN101732795B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Electrotherapy Devices (AREA)

Abstract

The invention discloses a pacemaking generation device comprising an exciting source and an electrode terminal for contacting with a biosome, wherein the exciting source is used for providing pacemaking pulse for the pacemaking generation device and outputs the pacemaking pulse to the electrode terminal; the pacemaking generation device also comprises a control unit and an impedance detection unit; the impedance detection unit is connected with the control unit which is connected with the exciting source; and the control unit is used for responding the impedance detected by the impedance detection unit, calculating a target voltage value, converting the target voltage value into corresponding voltage control level, outputting the voltage control level to the exciting source and controlling the exciting source to output corresponding power. The pacemaking generation device can dynamically adjust the power output in time, thereby effectively reducing the power consumption of a circuit.

Description

Pacemaking generation device and control method thereof
[technical field]
The present invention relates to a kind of pacemaking generation device.
[background technology]
Often need carry out external noinvasive pace-making to patient in clinical emergency aid and treatment occasion and obtain rescued effect timely, the advantage of external pace-making has: 1) need not conduit or acupuncture, to the human zero damage; 2) do not need to install conduit, operation fast; Be the effective treatment meanss of first aid diagnosis and treatment.Different with pace-making in the body, adhesive type electrode terminal sheet is used in external pacemaker more, and also mode in the body of human body impedance excursion during treatment requires external pacemaker can adapt to bigger impedance ranges and exports stabilizing effective pulse.
External human body breast resistance scope is wide than the body internal impedance, general excursion is from 20 ohm~200 ohm, clinical effective stimulus pulse current excursion 5mA~200mA, for guaranteeing under maximum impedance, can export maximum effective current, current impulse generation circuit need have the fan-out capability that transient power consumption reaches 8W so, if the actual patient impedance is little, as 20 ohm, so the Shi Ji useful power consumption that is used for pacemaker impulse has only 0.8W, both power consumptions differ 10 times, and other 7.2W power consumption will be led to superheated form consumption on the device of current impulse generation circuit.
The shortcoming of this design is: the output of pacemaker can not change with the real-time impedance under different patients or patient's the different conditions, may cause following problem: first, circuit devcie is the outer heat loss of commitment always, the circuit temperature rise, for reducing this temperature rise, need increase fin to device and guarantee that under the condition that works long hours the temperature rise of chip can not surpass rated temperature, prevent that overtemperature from causing Devices Characteristics to change or fault.The second, the power consumption of circuit is in higher relatively level always.In clinical emergency treatment and treatment use occasion, instrument miniature portableization, low-power consumption are the development trends of instrument.Especially to battery powered apparatus, reduce effectively prolongs standby time of power consumption, can improve service efficiency.Its heating effect of low power consuming devices is also relatively low simultaneously, to accomplishing the small-sized and portable more favourable of equipment.
[summary of the invention]
Main purpose of the present invention solves the problems of the prior art exactly, and a kind of low-power consumption pacemaking generation device and control method thereof are provided.
For achieving the above object, the invention provides a kind of pacemaking generation device, comprise driving source and the electrode terminal that is used to contact organism, described driving source is used to pacemaking generation device that pacemaker impulse is provided and pacemaker impulse is outputed to electrode terminal, described pacemaking generation device also comprises control unit and impedance acquiring unit, described impedance acquiring unit links to each other with control unit, described control unit links to each other with driving source, the impedance of the organism of described control unit responsive impedance acquiring unit output, calculate target voltage values, target voltage values is converted to the correspondent voltage control level, and the output voltage control level is controlled described driving source and is exported corresponding power to driving source.
In one embodiment, described control unit comprises a computing module and a DA transducer, described computing module is used to calculate target voltage values, described target voltage values increases with the increase of the product of the pacemaker current value of the resistance value of impedance acquiring unit output and setting, a described DA transducer is used for the digital quantity of target voltage values is converted to mimic Control of Voltage level, and output to described driving source, control described driving source and export corresponding pace-making driving voltage.
In one embodiment, described driving source comprises voltage source and current source, described voltage source provides driving voltage for described current source, described current source is used to produce the pacemaker impulse of setting width and frequency, a described DA transducer outputs to voltage source with the Control of Voltage level, the output voltage of control voltage source.Described control unit also comprises the 2nd DA transducer, described the 2nd DA transducer is used for the pacemaker current value that the operator sets is converted to mimic Current Control level, and output to described current source with pulse mode, the pulse that the output of control current source has predetermined pacemaker current and pacing frequency according to the frequency of setting.
The present invention also provides a kind of pacemaking generation device control method, may further comprise the steps:
Obtain the impedance of organism;
Output according to described impedance adjustment driving source.
In one embodiment, the output of adjusting driving source may further comprise the steps: obtain predetermined pacemaker current value; Regulate the pace-making driving voltage of driving source output according to the product of described impedance and predetermined pacemaker current value.
In another kind of embodiment, the step of regulating the pace-making driving voltage according to the product of described impedance and predetermined pacemaker current value may further comprise the steps:
Calculate target voltage values, the product that described target voltage values equals described impedance and predetermined pacemaker current value multiply by a coefficient adds a constant;
The digital quantity of target voltage values is converted to mimic Control of Voltage level;
Described driving source is according to the corresponding pace-making driving voltage of Control of Voltage level output.
The invention has the beneficial effects as follows: the present invention determines the power output of driving source for the big situation of external impedance excursion, also can guarantee to produce enough effective currents on the patient according to the impedance parameter that is operated organism.For the big situation of impedance,, make enough electric current fan-out capabilities by the dynamic adjustments driving source.Under the little situation of resistance, circuit can in time dynamically be adjusted driving source output, effectively reduces circuit power consumption.In wide impedance variation scope, the dynamic adjustment of driving source, can make the work efficiency of circuit maintain a high level always, especially for small-sized or portable set, under the suitable situation of powering quantity, this high efficiency pulse outputting unit can more effective output pacemaker impulse, effectively prolongs standby time reduces the circuit thermal losses.This pulse generating circuit is particularly suitable for using in the big external pace-making occasion of impedance variation scope.
[description of drawings]
Fig. 1 is the theory diagram of a kind of embodiment of pacemaking generation device;
Fig. 2 is the voltage source structural representation of an embodiment of the present invention;
Fig. 3 is the current source structural representation of an embodiment of the present invention;
Fig. 4 is the theory diagram of the another kind of embodiment of pacemaking generation device;
Fig. 5 is the flow chart of an embodiment of the present invention;
Fig. 6 is the impedance detection cellular construction sketch map of an embodiment of the present invention;
Fig. 7 is the flow chart of the another kind of embodiment of the present invention;
Fig. 8 is the flow chart of another embodiment of the present invention.
[specific embodiment]
The application's feature and advantage will be elaborated in conjunction with the accompanying drawings by embodiment.
Please refer to Fig. 1, pacemaking generation device comprises: driving source, be used to contact the electrode terminal 10 of organism, control unit 11 and impedance acquiring unit, in the present embodiment, the impedance acquiring unit is impedance detection unit 12, described driving source is used to pacemaking generation device that pacemaker impulse is provided and pacemaker impulse is outputed to electrode terminal, described impedance detection unit 12 links to each other with control unit 11, described control unit 11 links to each other with driving source, described impedance detection unit 12 is used for detecting the access impedance that is operated organism (for example patient) 20, the impedance of the organism that described control unit responsive impedance detecting unit detects, and output control signal, control the output of described driving source, by the output of control driving source, thus the power consumption of control pacemaking generation device.In the present embodiment, described driving source comprises voltage source 13 and current source 14, and voltage source 13 provides driving voltage for current source 14, and current source 14 is used for producing the pacemaker impulse of setting width and frequency according to operator's setting.
In one embodiment, described control unit comprises computing module and a DA (digital-to-analogue) transducer, and a DA transducer can be realized by hardware configuration, also can pass through software set, can be hardware configuration independently, also can be integrated in the chip of control unit.Computing module can be separately a microprocessor, also can be integrated into a microprocessor jointly with a DA transducer.In advance, control unit can receive pacemaker current and the pacing frequency that the operator sets, and pacemaker current is set according to different patients' concrete situation with pacing frequency.Control unit calculates the resistance value that the measures pacemaker current by computing module and setting, obtain the target voltage values of the pace-making voltage source of needs, the increase of the product of the resistance value that target voltage values detects with the impedance detection unit and the pacemaker current value of setting increases, in one embodiment, the computing formula of target voltage values is:
Vout=A*R*Iout+B
Vout is the driving voltage of voltage source output in the formula, and Iout is predetermined pacemaker current, and R is a human body impedance, and A and B are coefficient.
Target voltage values Vout also can adopt R*Iout to calculate.But because of current source has internal resistance, can consume one part of current, so the driving voltage Vout of voltage source output should have certain surplus, A and B can calculate according to circuit characteristic.
The one DA transducer is converted to a mimic Control of Voltage level Vout_DA with the digital quantity of this target voltage values, output to voltage source, be used as the voltage reference of voltage feedback loop,, produce the drive current source required voltage then by the inverse-excitation converting topological structure.
Voltage source can adopt multiple circuit to realize, in one embodiment, the structural representation of voltage source as shown in Figure 2, operational amplifier U39 and audion Q7 constitute a current source, flow through signal voltage (the be Control of Voltage level) decision of the size of Q7 electric current by DA transducer output.The reference edge node Vref voltage of stabilivolt U38 is stabilized in 2.5V, so the output of a pace-making voltage PACE_V+ and a DA transducer is linear scale.
After the pace-making voltage of having regulated voltage source output, control unit is again according to default pacemaker current value and pacing frequency, the 2nd DA transducer by control unit converts a mimic Current Control level Iout_DA to and exports to adjustable current source, the control signal of the 2nd DA transducer output is sent with pulse mode, like this current source pacing frequency that just generation needs between patient's electrode slice and the pulse of pacemaker current.When the Iout_DA signal voltage is zero, then stop pace-making output.
The 2nd DA transducer can be realized by hardware configuration, also can pass through software set, can be hardware configuration independently, also can be integrated in the chip of control unit.
Current source can adopt multiple circuit to realize that in one embodiment, the controllable current source structure chart mainly comprises amplifying circuit U31 and metal-oxide-semiconductor Q9 as shown in Figure 3, and Current Control level Iout_DA is input to the input of amplifying circuit U31.Metal-oxide-semiconductor Q9 exports pacemaker impulse.
By the impedance detection unit, obtain current interelectrode organism (for example human body) resistance value, adjust the driving voltage of voltage source according to the current value of human body impedance and needs, make voltage source output can satisfy the requirement of drive current load.Be the pacemaker impulse of Iout by control unit control pacemaker current source frequency output size as required then.In wide impedance variation scope, voltage source can dynamically be adjusted, and can make the work efficiency of circuit maintain a high level always, effectively reduces the power attenuation in the circuit.
In another kind of embodiment, also the connection situation of leading is judged.As shown in Figure 4, pacemaking generation device comprises voltage source 13, current source 14, electrode terminal 10, control unit 11, impedance detection unit 12 and relay 15, relay 15 is connected between voltage source 13, current source 14 and the electrode terminal 10, the control end of relay 15 is coupled to control unit 11, described control unit 11 compares resistance value and the predetermined threshold value that impedance detection unit 12 detects, and switches switching on and off between the state according to the comparative result control relay.If for example resistance value is less than predetermined threshold value, then control relay is connected, thereby pacemaker impulse is applied on the tested organism 20, if resistance value greater than predetermined threshold value, then control relay disconnects, thereby stops pacemaker impulse being applied on the tested organism 20.
Pacemaker is regulated the power of output by the driving voltage of regulating output, thereby make output can follow the real-time impedance of tested organism and change, promptly dynamically adjust the power consumption of pulse generating circuit, the power of the diffusing consumption of forms such as circuit heat is saved, then can effectively increase work efficiency, reduce the circuit heating, prolong the machine works time.The workflow of pacemaker may further comprise the steps as shown in Figure 5:
1, after receiving the instruction that pace-making begins, obtains the real-time impedance R of impedance detection unit output earlier.
2, whether judge real-time impedance R greater than predetermined threshold value, if then illustrate to lead to come off, can stop pacemaker impulse being applied on the tested organism, for example give relay by control unit output control signal, control relay disconnects, thereby pacemaker and tested organism are separated from.If impedance R does not exceed predetermined threshold value in real time, then explanation is led connection normally, then pacemaker impulse is applied on the tested organism, for example gives relay by control unit output control signal, the control relay closure, thus the pacemaker impulse of output is applied on the tested organism.
3, calculate the Vout_DA controlled quentity controlled variable according to real-time impedance R that detects and default pacemaker current value, the voltage of regulation voltage source output.
4, calculate the Iout_DA controlled quentity controlled variable according to default pacemaker current value, the output of control current source has the pacemaker impulse of electric current I out and setpoint frequency.
Judge whether also to need to export pacemaker impulse behind each output pacemaker impulse, above-mentioned steps if desired then circulates.Between the pacemaker impulse period of output, still monitor impedance in real time, real-time resistance value and predetermined threshold value are compared, if resistance value less than predetermined threshold value, then is applied to pacemaker impulse on the tested organism, if resistance value greater than predetermined threshold value, then stops pacemaker impulse being applied on the tested organism.Pacemaker impulse each time send finish after, according to current resistance value, recomputate the adjustment voltage of voltage source, and, adjust circuit output according to the value of the new Vout_DA of result of calculation output, finish power consumption control.
The unitary a kind of implementation of impedance detection is to realize by hardware: convert impedance signal to level signal through described hardware impedance collection circuit, after the AD conversion, calculate resistance value by control unit according to the linear relationship of circuit.The unitary a kind of circuit structure of impedance detection as shown in Figure 6, comprise the carrier generator that is linked in sequence, capacitance coupling circuit, difference amplifier, bandwidth-limited circuit, half-wave rectifying circuit and low-pass filtering rectification circuit, described carrier generator is used to produce high-frequency carrier signal, the high frequency carrier square-wave signal is to be produced by PWM, the square-wave signal of its generation is the pulse signal of 2.5V through MOSFET output same frequency and amplitude at first, square-wave signal after amplifying through amplifier is again followed and is oppositely amplified through amplifier respectively again through high pass and is divided into the opposite pulse of two-way direction and enters capacitance coupling circuit, the input of capacitance coupling circuit also the RA by representing two limb leads respectively and LL (RA is a right arm, LL is left lower limb) input organism impedance signal, these two signal differentials obtain II guided wave shape signal later on.Capacitance coupling circuit is modulated to the organism impedance signal in the high-frequency carrier signal, the carrier signal of having modulated the human body impedance signal is after buffering is amplified by difference amplifier, amplify through bandwidth-limited circuit again, output to half-wave rectifying circuit, enter into AD detector, this direct current signal and the human body impedance linear correlation of control unit again through the low-pass filter circuit rectification output dc waveform of back to waveform through the folk prescription of halfwave rectifier output.
When impedance detection unit output be analogue signal the time, the impedance detection unit outputs to the AD detector earlier with impedance signal, the AD detector can be the part of control unit, also can be an individual devices that is positioned at outside the control unit.AD converter is the digital quantity of can controlled unit (for example CPU) handling with analog signal conversion.
The unitary another kind of implementation of impedance detection is that indirect other calculation of parameter of utilizing obtain resistance value.For example impedance equals to be applied to the voltage at impedance two ends divided by the electric current that flows through impedance.The impedance detection unit comprises voltage acquisition module, current acquisition module and resistance calculations module, described voltage acquisition module is used to gather the voltage that is applied on the organism, described current acquisition module is used for the electric current of acquisition stream through organism, the input of described resistance calculations module connects voltage acquisition module and current acquisition module respectively, the outfan of described resistance calculations module is coupled to control unit, the electric current that the voltage and current acquisition module that described resistance calculations module responds voltage acquisition module is gathered is gathered, calculate resistance value, and resistance value is outputed to control unit.Can obtain resistance value accurately by voltage and current being sampled and calculating also.
In the pace-making process, itself just need monitor in real time the current/voltage of the human body of flowing through, whether normal with the treatment electric current of judging current output, be applied to the voltage safety whether on the human body.Body current and body voltages convert corresponding voltage value to by special testing circuit, giving control unit after this value is changed through AD handles, control unit obtains current body current value and body voltages value according to sampled result, and whether independent judgment electric current and voltage is normal.The ratio that calculates electric current and voltage simultaneously just can obtain the human body impedance value.Its flow chart can send the little current impulse of a utmost point short time in beginning earlier before the pace-making and survey current impedance as shown in Figure 7, if impedance is normally then according to this impedance initialization voltage source, if impedance unusually then stop pace-making.In the process that pacemaker impulse sends, there is electric current to be applied on the human body, the method for this current-voltage sampling computing impedance can be carried out in real time, if it is excessive to detect human body impedance, it is normal then can to judge the current state malunion of leading, and stops pace-making.If impedance is normal, then in the pacemaker impulse gap, recomputate the control voltage Vout value in pacemaker current source, and regulate Vout_DA, make the output of voltage source drive current source on human body, produce the suitable voltage of setting electric current.After the voltage adjustment finished, when control unit was exported at next pacemaker impulse, according to pacemaker current Iout value, the pacemaker impulse of width was set in control Iout_DA output.
In other embodiment, the impedance detection unit further adopts direct hardware impedance detection circuit and the common human body impedance of two kinds of methods of software parameter detection computations indirectly, receive pace-making begin before by the human body impedance of hardware impedance detection unit, voltage source is carried out initialization.Begin the back at pace-making and calculate human body impedance, finish dynamic adjustment voltage source V out by software detecting method.The human body impedance that hardware impedance detection unit can also be detected in the pace-making process and the human body impedance of indirect software parameter detection computations compare, if when the result difference that arrives of two kinds of detection methods is bigger, then can have judged a kind of impedance detection method and occur unusually.Control flow as shown in Figure 8.
In the foregoing description, the impedance acquiring unit adopts the impedance detection unit, can detect the real-time impedance that is operated organism, and output can be become according to the impedance of different organisms or the impedance under the same organism different conditions.Mode as an alternative, the impedance acquiring unit can also be the impedance memory element, for the patient who is in hospital for a long time, its resistance value can be stored in the impedance memory element in advance, when this patient is carried out pace-making, can from the impedance memory element, read its resistance value and be used for the pace-making operation, this resistance value is used for the beginning of pace-making as initial value, in the pace-making process, can detect patient's resistance value in real time, and the resistance value that records is updated in the impedance memory element, be used for the control of driving source.
In the foregoing description, be used for pacemaker and the isolated relay of organism can also be replaced with other switch.
In sum, the present invention can dynamically adjust pacemaker impulse generation circuit, make pulse stable in bigger impedance ranges output, effectively reduce the power consumption of pulse generating circuit, when impedance is little, just can produce the pacemaker impulse that needs with low-voltage, when impedance is higher, heighten voltage source output, make current source have enough carrying load abilities, produce the pacemaker impulse of satisfying the demand.
Above content be in conjunction with concrete preferred implementation to further describing that the present invention did, can not assert that concrete enforcement of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.

Claims (16)

1. pacemaking generation device, comprise driving source and the electrode terminal that is used to contact organism, described driving source is used to pacemaking generation device that pacemaker impulse is provided and pacemaker impulse is outputed to electrode terminal, it is characterized in that: described pacemaking generation device also comprises control unit and impedance acquiring unit, described impedance acquiring unit links to each other with control unit, described control unit links to each other with driving source, the impedance of the organism of described control unit responsive impedance acquiring unit output, calculate target voltage values, described target voltage values is converted to the correspondent voltage control level, and export described Control of Voltage level to driving source, control described driving source and export corresponding power.
2. pacemaking generation device as claimed in claim 1, it is characterized in that: described control unit comprises a computing module and a DA transducer, described computing module is used to calculate target voltage values, described target voltage values increases with the increase of the product of the pacemaker current value of the resistance value of impedance acquiring unit output and setting, a described DA transducer is used for the digital quantity of target voltage values is converted to mimic Control of Voltage level, and output to described driving source, control described driving source and export corresponding pace-making driving voltage.
3. pacemaking generation device as claimed in claim 2 is characterized in that: the product that described target voltage values equals the pacemaker current value of resistance value and setting multiply by a coefficient adds a constant.
4. pacemaking generation device as claimed in claim 2, it is characterized in that: described driving source comprises voltage source and current source, described voltage source provides driving voltage for described current source, described current source is used to produce the pacemaker impulse of setting width and frequency, a described DA transducer outputs to voltage source with the Control of Voltage level, the output voltage of control voltage source.
5. pacemaking generation device as claimed in claim 4, it is characterized in that: described control unit also comprises the 2nd DA transducer, described the 2nd DA transducer is used for the pacemaker current value that the operator sets is converted to mimic Current Control level, and output to described current source with pulse mode, the pulse that the output of control current source has predetermined pacemaker current and pacing frequency according to the frequency of setting.
6. as each described pacemaking generation device in the claim 1 to 5, it is characterized in that: described impedance acquiring unit is the impedance detection unit that is used for the real-time resistance value of detection of biological body.
7. pacemaking generation device as claimed in claim 6, it is characterized in that: described pacemaking generation device also comprises the switch that is connected between driving source and the electrode terminal, the control end of described switch is coupled to control unit, described control unit compares resistance value and the predetermined threshold value that the impedance detection unit detects, and switches switching on and off between the state according to the comparative result gauge tap.
8. pacemaking generation device as claimed in claim 6, it is characterized in that: described impedance detection unit comprises the carrier generator that is linked in sequence, capacitance coupling circuit, difference amplifier, bandwidth-limited circuit, half-wave rectifying circuit and low-pass filtering rectification circuit, described control unit also comprises the AD detector, described carrier generator is used to produce high-frequency carrier signal, and be divided into the opposite pulse of two-way direction and enter capacitance coupling circuit, the input of described capacitance coupling circuit also receives the organism impedance signal, the carrier signal order of having modulated the organism impedance signal is through difference amplifier, bandwidth-limited circuit, half-wave rectifying circuit and low-pass filtering rectification circuit are handled, and the output dc waveform is to described AD detector.
9. pacemaking generation device as claimed in claim 6, it is characterized in that: described impedance detection unit comprises voltage acquisition module, current acquisition module and resistance calculations module, described voltage acquisition module is used to gather the voltage that is applied on the organism, described current acquisition module is used for the electric current of acquisition stream through organism, the input of described resistance calculations module connects voltage acquisition module and current acquisition module respectively, the outfan of described resistance calculations module is coupled to control unit, the electric current that the voltage and current acquisition module that described resistance calculations module responds voltage acquisition module is gathered is gathered, the computing impedance value.
10. pacemaking generation device control method is characterized in that may further comprise the steps:
Obtain the impedance of organism;
Output according to described impedance adjustment driving source.
11. control method as claimed in claim 10 is characterized in that: the output of described adjusting driving source may further comprise the steps: obtain predetermined pacemaker current value; Regulate the pace-making driving voltage of driving source output according to the product of described impedance and predetermined pacemaker current value.
12. control method as claimed in claim 11 is characterized in that: the step of regulating the pace-making driving voltage according to the product of described impedance and predetermined pacemaker current value may further comprise the steps:
Calculate target voltage values, the product that described target voltage values equals impedance and predetermined pacemaker current value multiply by a coefficient adds a constant;
The digital quantity of described target voltage values is converted to mimic Control of Voltage level;
Described driving source is according to the corresponding pace-making driving voltage of Control of Voltage level output.
13. as each described control method in the claim 10 to 12, it is characterized in that: described impedance is the real-time impedance of the organism of detection.
14. control method as claimed in claim 13, it is characterized in that: further comprising the steps of in the process of described output pacemaker impulse: described real-time resistance value and predetermined threshold value are compared, if described resistance value is less than predetermined threshold value, then pacemaker impulse is applied on the tested organism, if described resistance value greater than predetermined threshold value, then stops pacemaker impulse being applied on the tested organism.
15. control method as claimed in claim 13, it is characterized in that: further comprising the steps of before the output pacemaker impulse: the real-time impedance of obtaining organism, described real-time resistance value and predetermined threshold value are compared, if described resistance value is less than predetermined threshold value, then pacemaker impulse is applied on the tested organism, if described resistance value greater than predetermined threshold value, then stops pacemaker impulse being applied on the tested organism.
16. control method as claimed in claim 13, it is characterized in that: the described step of obtaining the real-time impedance of organism may further comprise the steps: the voltage that is applied on the tested organism is sampled, electric current on the tested organism of flowing through is sampled, described voltage is obtained resistance value divided by electric current.
CN 200810217603 2008-11-21 2008-11-21 Pacemaking generation device and control method thereof Active CN101732795B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200810217603 CN101732795B (en) 2008-11-21 2008-11-21 Pacemaking generation device and control method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200810217603 CN101732795B (en) 2008-11-21 2008-11-21 Pacemaking generation device and control method thereof

Publications (2)

Publication Number Publication Date
CN101732795A true CN101732795A (en) 2010-06-16
CN101732795B CN101732795B (en) 2013-06-12

Family

ID=42457155

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200810217603 Active CN101732795B (en) 2008-11-21 2008-11-21 Pacemaking generation device and control method thereof

Country Status (1)

Country Link
CN (1) CN101732795B (en)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104399183A (en) * 2014-11-25 2015-03-11 西安交通大学 Automatic wake-up circuit applicable to cardiac pacemaker
CN104406633A (en) * 2014-11-26 2015-03-11 深圳麦开网络技术有限公司 Physique and environment monitor and activating method thereof
CN104771806A (en) * 2015-05-12 2015-07-15 中国人民解放军第三军医大学第二附属医院 Infusion pump multi-parameter signal collecting device and method based on impedance changes
CN105983178A (en) * 2015-02-02 2016-10-05 深圳市科曼医疗设备有限公司 Pace-making generation device
CN106207283A (en) * 2016-07-26 2016-12-07 同济大学 A kind of supervising device of vehicle-mounted multiple-connected battery group
CN107102218A (en) * 2016-02-19 2017-08-29 创领心律管理医疗器械(上海)有限公司 Pulse generating unit
CN108290049A (en) * 2015-12-03 2018-07-17 美敦力公司 The outer cardiac pacing system of angiocarpy for delivering compound pacemaker impulse
CN109378009A (en) * 2018-09-21 2019-02-22 中国航空无线电电子研究所 Airborne alarm instantaneous speech power
CN109771817A (en) * 2019-01-29 2019-05-21 深圳市科曼医疗设备有限公司 A kind of constant current stimulation circuit of Dynamic voltage scaling
CN109982742A (en) * 2016-11-18 2019-07-05 欧姆龙健康医疗事业株式会社 Electric therapeutic apparatus and treatment system
CN109982743A (en) * 2016-11-18 2019-07-05 欧姆龙健康医疗事业株式会社 Electric therapeutic apparatus and treatment system
WO2020154906A1 (en) * 2019-01-29 2020-08-06 深圳市科曼医疗设备有限公司 Constant-current stimulation circuit with dynamic voltage adjustment
CN112039178A (en) * 2020-08-31 2020-12-04 赛诺微医疗科技(浙江)有限公司 Control method and device of irreversible electroporation ablation device

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5201808A (en) * 1992-02-10 1993-04-13 Telectronics Pacing Systems, Inc. Minute volume rate-responsive pacemaker employing impedance sensing on a unipolar lead
IT1272265B (en) * 1994-06-06 1997-06-16 Medtronic Inc Societa Del Minn IMPROVEMENT IN CARDIAC STIMULATOR SYSTEMS
US5507785A (en) * 1994-12-21 1996-04-16 Intermedics, Inc. Rate responsive cardiac pacemaker with biphasic impedance sensing and method
IL125424A0 (en) * 1998-07-20 1999-03-12 New Technologies Sa Ysy Ltd Pacing with hemodynamic enhancement
US5824019A (en) * 1996-10-11 1998-10-20 Medtronic, Inc. Pacing system with physiologically timed ventricular pacing
US8428717B2 (en) * 2003-10-14 2013-04-23 Medtronic, Inc. Method and apparatus for monitoring tissue fluid content for use in an implantable cardiac device

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104399183B (en) * 2014-11-25 2016-06-08 西安交通大学 A kind of automatic wake-up circuit being applied to cardiac pacemaker
CN104399183A (en) * 2014-11-25 2015-03-11 西安交通大学 Automatic wake-up circuit applicable to cardiac pacemaker
CN104406633A (en) * 2014-11-26 2015-03-11 深圳麦开网络技术有限公司 Physique and environment monitor and activating method thereof
CN105983178A (en) * 2015-02-02 2016-10-05 深圳市科曼医疗设备有限公司 Pace-making generation device
CN105983178B (en) * 2015-02-02 2019-03-08 深圳市科曼医疗设备有限公司 Pacemaking generation device
CN104771806B (en) * 2015-05-12 2018-01-16 中国人民解放军第三军医大学第二附属医院 Infusion pump multi-parameter signals harvester and method based on impedance variations
CN104771806A (en) * 2015-05-12 2015-07-15 中国人民解放军第三军医大学第二附属医院 Infusion pump multi-parameter signal collecting device and method based on impedance changes
US11883677B2 (en) 2015-12-03 2024-01-30 Medtronic, Inc. Extra-cardiovascular cardiac pacing system for delivering composite pacing pulses
CN108290049A (en) * 2015-12-03 2018-07-17 美敦力公司 The outer cardiac pacing system of angiocarpy for delivering compound pacemaker impulse
US11406838B2 (en) 2015-12-03 2022-08-09 Medtronic, Inc. Extra-cardiovascular cardiac pacing system for delivering composite pacing pulses
CN108290049B (en) * 2015-12-03 2021-12-28 美敦力公司 Extravascular cardiac pacing system for delivery of composite pacing pulses
CN107102218B (en) * 2016-02-19 2019-09-17 创领心律管理医疗器械(上海)有限公司 Pulse generating unit
CN107102218A (en) * 2016-02-19 2017-08-29 创领心律管理医疗器械(上海)有限公司 Pulse generating unit
CN106207283A (en) * 2016-07-26 2016-12-07 同济大学 A kind of supervising device of vehicle-mounted multiple-connected battery group
CN109982743A (en) * 2016-11-18 2019-07-05 欧姆龙健康医疗事业株式会社 Electric therapeutic apparatus and treatment system
CN109982742A (en) * 2016-11-18 2019-07-05 欧姆龙健康医疗事业株式会社 Electric therapeutic apparatus and treatment system
CN109982743B (en) * 2016-11-18 2022-11-18 欧姆龙健康医疗事业株式会社 Electrical therapeutic apparatus and therapeutic system
CN109378009A (en) * 2018-09-21 2019-02-22 中国航空无线电电子研究所 Airborne alarm instantaneous speech power
WO2020154906A1 (en) * 2019-01-29 2020-08-06 深圳市科曼医疗设备有限公司 Constant-current stimulation circuit with dynamic voltage adjustment
CN109771817A (en) * 2019-01-29 2019-05-21 深圳市科曼医疗设备有限公司 A kind of constant current stimulation circuit of Dynamic voltage scaling
CN112039178A (en) * 2020-08-31 2020-12-04 赛诺微医疗科技(浙江)有限公司 Control method and device of irreversible electroporation ablation device

Also Published As

Publication number Publication date
CN101732795B (en) 2013-06-12

Similar Documents

Publication Publication Date Title
CN101732795B (en) Pacemaking generation device and control method thereof
CN110212767A (en) Realize the digital control method of LLC resonant converter multistep frequency modulation
CN209117841U (en) DC load is set to have the device of exchange load function
WO2023109916A1 (en) Power control circuit and power control method for electromagnetic heating device
CN104753359B (en) A kind of power frequency electric power electronic transformer and its implementation
CN115607837A (en) Body surface neuromuscular electrical stimulation device and control method thereof
CN105517217A (en) Single chip microcomputer-controlled high frequency induction heating power supply
CN103904883B (en) Load distribution control method and device for parallel direct current switch power supply
KR101693700B1 (en) Bidirectional Power Converter
CN105307305A (en) LED power supply control device and TV set
CN108448741A (en) A kind of adaptive constant pressure high efficiency wireless power supply system
CN110855250B (en) Linear power amplifier driving method with variable power supply voltage
CN205430059U (en) A current -sharing control circuit, power and power module for DCDC power
CN205039717U (en) Output polarity automatic switching's D.C. regulated power supply
CN205544936U (en) Intelligence frequency conversion buck converter
CN108062129A (en) A kind of temperature control method and its system of gauze reactor
CN109849526B (en) Heating voltage control circuit of thermal printing head and printing equipment
CN108282105B (en) Radio frequency ablation power supply
CN208386425U (en) Intelligent digital medical treatment power supply
CN205411229U (en) Supersound handle driving system
CN202458763U (en) Dental therapeutic equipment
CN201656537U (en) Accumulator charger
CN205921197U (en) Semiconductor laser power supply device
CN110381633A (en) Power factor optimization circuit and the LED drive circuit for applying it
CN205123593U (en) Voltage -stabilized power supply

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant