CN101732666A - Chinese medicinal composition for treating hepatitis end-stage diseases and preparation method thereof - Google Patents
Chinese medicinal composition for treating hepatitis end-stage diseases and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a new Chinese medicinal composition for treating hepatitis end-stage diseases and a preparation method thereof. The Chinese medicinal composition comprises the following raw materials: dried orange peel, radix curcumae, immature bitter orange, slender dutchmanspipe root, indigowoad leaf, nutgrass galingale rhizome, szechwan chinaberry fruit, combined spicebush root, golden thread, wild chrysanthemum, dandelion, Chinese thorowax root, houttuynia cordata thumb, bezoar, redroot gromwell root, kudzuvine root, raw gypsum, rhizoma anemarrhenae, glabrous greenbrier rhizome, weeping forsythiae capsule, double blossom, mongolian snakegourd root, lightyellow sophora root, rhubarb, Chinese dwarf cherry seed, oriental waterplantain rhizome, longhairy antenoron herb, giant knotweed rhizome, longstamen onion bulb, malt, yanhusuo, peach seed, safflower, leonurus heterophyllus, danshen root and chaff flower root. The Chinese medicinal composition can be prepared into any common oral preparations by a conventional Chinese medicinal preparation method. The Chinese medicinal composition can obviously improve symptoms such as debilitation, appetite reduction, nausea, sickness, hepatauxe and liver damage of people with last-stage hepatitis, and aundice and fever of some patients, can obviously improve symptoms such as gum errhysis, nosebleed, skin ecchymosis, hematochezia, hematemesis, hematuria, purpura occurring in lower limbs and buttocks, bloody pleural effusion or ascites and the like of patients with chronic hepatitis or last-stage fulminant hepatitis, and is characterized by exact clinical effects, obvious treatment effect and quick response. Because medicinal and edible medicaments stipulated by National Formulary are basically adopted for combination, the Chinese medicinal composition has the advantages of low cost, and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of hepatitis end-stage diseases.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment hepatitis end-stage diseases of crude drug with the Chinese herbal medicine.
Background technology
China is one of serious popular district of hepatitis in the world, various hepatitis is presenting ascendant trend, treat timely and effectively as not taking, liver constantly sustains damage, and it is fast to have arrived hepatitis PD in late period, symptom of digestive tract is serious, many companion's severe jaundices, loss of appetite, bleeding tendency etc. often cause diseases such as hepatic ascites, hepatorenal syndrome, liver cirrhosis, hepatocarcinoma or liver failure, and mortality rate is about more than 70%, have a strong impact on life and life, just becoming a big killer of human health.
Still lack clear and definite effectively Therapeutic Method at present, modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment hepatitis end-stage diseases, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out the natural plant of heat-clearing and toxic substances removing, easing the affected liver yin nourishing, depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment hepatitis end-stage diseases that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment hepatitis end-stage diseases of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of hepatitis end-stage diseases of the present invention, the component of main following weight portion is formed:
Pericarpium Citri Reticulatae 1～50 gram; Radix Curcumae 1～40 gram; Fructus Aurantii Immaturus 1～50 gram; Semen Raphani 1～40 gram; Radix Aristolochiae 1～40 gram; Folium Isatidis 1～50 gram; Rhizoma Cyperi 1～50 gram; Fructus Toosendan 1～50 gram; the Radix Linderae 1～50 gram; Massa Medicata Fermentata 1～50 gram; Semen Arecae 1～40 gram; Radix Scutellariae 1～40 gram; Rhizoma Coptidis 1～40 gram; Fructus Gardeniae 1～40 gram; Radix Rehmanniae 1～40 gram; Flos Chrysanthemi Indici 1～40 gram; Herba Taraxaci 1～40 gram; Radix Bupleuri 1～40 gram; Herba Houttuyniae 1～50 gram; Herba Scutellariae Barbatae 1～40 gram; Calculus Bovis 1～20 gram; Radix Arnebiae (Radix Lithospermi) 1～40 gram; Radix Puerariae 1～50 gram; Gypsum Fibrosum 1～50 gram; the Rhizoma Anemarrhenae 1～40 gram; Indigo Naturalis 1～30 gram; Herba Patriniae 1～50 gram; Fructus Canarii 1～40 gram; Rhizoma Smilacis Glabrae 1～50 gram; Fructus Forsythiae 1～40 gram; Flos Lonicerae 1～50 gram; Rhizoma Paridis 1～40 gram; the Radix Pulsatillae 1～50 gram.
Be preferably:
Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Fructus Canarii 20 grams; Rhizoma Smilacis Glabrae 30 grams; Fructus Forsythiae 20 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
Radix Trichosanthis 1～50 gram, Mirabilitum crystallina 1～50 gram, Semen Cassiae 1～40 gram, Radix Sophorae Flavescentis 1～40 gram, Radix Et Rhizoma Rhei 1～30 gram, Folium Sennae 1～40 gram, Semen Pruni 1～30 gram, Semen Plantaginis 1～40 gram, Rhizoma Alismatis 1～40 gram, Herba Lysimachiae 1～50 gram, Rhizoma Polygoni Cuspidati 1～40 gram, Pericarpium Arecae 1～50 gram, Fructus Citri Sarcodactylis 1～50 gram, Bulbus Allii Macrostemonis 1～40 gram, Fructus Hordei Germinatus 1～50 gram, Fructus Setariae Germinatus 1～40 gram, Fructus Crataegi 1～40 gram, Endothelium Corneum Gigeriae Galli 1～30 gram, Rhizoma Corydalis 1～40 gram, Semen Persicae 1～30 gram, Flos Carthami 1～30 gram, Herba Leonuri 1～50 gram, Radix Salviae Miltiorrhizae 1～40 gram, Radix Achyranthis Bidentatae 1～40 gram, Olibanum 1～30 gram, Myrrha 1～30 gram.
Be preferably:
Radix Trichosanthis 30 gram, Mirabilitum crystallina 20 grams, Semen Cassiae 20 grams, Radix Sophorae Flavescentis 20 grams, Radix Et Rhizoma Rhei 20 grams, Folium Sennae 20 grams, Semen Pruni 20 grams, Semen Plantaginis 20 grams, Rhizoma Alismatis 20 grams, Herba Lysimachiae 30 grams, Rhizoma Polygoni Cuspidati 20 grams, Pericarpium Arecae 30 grams, Fructus Citri Sarcodactylis 20 grams, Bulbus Allii Macrostemonis 20 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Crataegi 15 grams, Endothelium Corneum Gigeriae Galli 20 grams, Rhizoma Corydalis 20 grams, Semen Persicae 15 grams, Flos Carthami 15 grams, Herba Leonuri 30 grams, Radix Salviae Miltiorrhizae 20 grams, Radix Achyranthis Bidentatae 20 grams, Olibanum 15 grams, Myrrha 15 gram.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.This is the important content of Thailand one and Pu (Beijing) Chinese medicine academy patent strategy.
The structure of Thailand one and Pu patent strategy is convenient to Chinese medicine and is realized standardization, scale, industrialization, modernization and industrialization.For traditional Chinese medicine development has been opened up a road that meets the Chinese medicine self-law with innovation.The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the hepatitis end-stage diseases patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve liver function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams; Radix Trichosanthis 30 grams; Mirabilitum crystallina 20 grams; Semen Cassiae 20 grams; Radix Sophorae Flavescentis 20 grams; Radix Et Rhizoma Rhei 20 grams; Folium Sennae 20 grams; Semen Pruni 20 grams; Semen Plantaginis 20 grams; Rhizoma Alismatis 20 grams; Herba Lysimachiae 30 grams; Rhizoma Polygoni Cuspidati 20 grams; Endothelium Corneum Gigeriae Galli 20 grams; Semen Persicae 15 grams; Flos Carthami 15 grams; Herba Leonuri 30 grams; Radix Salviae Miltiorrhizae 20 grams; Radix Achyranthis Bidentatae 20 grams; Olibanum 15 grams; Myrrha 15 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams; Radix Trichosanthis 30 grams; Mirabilitum crystallina 20 grams; Semen Cassiae 20 grams; Radix Sophorae Flavescentis 20 grams; Radix Et Rhizoma Rhei 20 grams; Folium Sennae 20 grams; Semen Pruni 20 grams; Semen Plantaginis 20 grams; Rhizoma Alismatis 20 grams; Herba Lysimachiae 30 grams; Rhizoma Polygoni Cuspidati 20 grams; Endothelium Corneum Gigeriae Galli 20 grams; Semen Persicae 15 grams; Flos Carthami 15 grams; Herba Leonuri 30 grams; Radix Salviae Miltiorrhizae 20 grams; Radix Achyranthis Bidentatae 20 grams; Olibanum 15 grams; Myrrha 15 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams; Radix Trichosanthis 30 grams; Mirabilitum crystallina 20 grams; Semen Cassiae 20 grams; Radix Sophorae Flavescentis 20 grams; Radix Et Rhizoma Rhei 20 grams; Folium Sennae 20 grams; Semen Pruni 20 grams; Semen Plantaginis 20 grams; Rhizoma Alismatis 20 grams; Herba Lysimachiae 30 grams; Rhizoma Polygoni Cuspidati 20 grams; Endothelium Corneum Gigeriae Galli 20 grams; Semen Persicae 15 grams; Flos Carthami 15 grams; Herba Leonuri 30 grams; Radix Salviae Miltiorrhizae 20 grams; Radix Achyranthis Bidentatae 20 grams; Olibanum 15 grams; Myrrha 15 grams.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams; Radix Trichosanthis 30 grams; Mirabilitum crystallina 20 grams; Semen Cassiae 20 grams; Radix Sophorae Flavescentis 20 grams; Radix Et Rhizoma Rhei 20 grams; Folium Sennae 20 grams; Semen Pruni 20 grams; Semen Plantaginis 20 grams; Rhizoma Alismatis 20 grams; Herba Lysimachiae 30 grams; Rhizoma Polygoni Cuspidati 20 grams; Endothelium Corneum Gigeriae Galli 20 grams; Semen Persicae 15 grams; Flos Carthami 15 grams; Herba Leonuri 30 grams; Radix Salviae Miltiorrhizae 20 grams; Radix Achyranthis Bidentatae 20 grams; Olibanum 15 grams; Myrrha 15 grams.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams; Radix Trichosanthis 30 grams; Mirabilitum crystallina 20 grams; Semen Cassiae 20 grams; Radix Sophorae Flavescentis 20 grams; Radix Et Rhizoma Rhei 20 grams; Folium Sennae 20 grams; Semen Pruni 20 grams; Semen Plantaginis 20 grams; Rhizoma Alismatis 20 grams; Herba Lysimachiae 30 grams; Rhizoma Polygoni Cuspidati 20 grams; Endothelium Corneum Gigeriae Galli 20 grams; Semen Persicae 15 grams; Flos Carthami 15 grams; Herba Leonuri 30 grams; Radix Salviae Miltiorrhizae 20 grams; Radix Achyranthis Bidentatae 20 grams; Olibanum 15 grams; Myrrha 15 grams.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating hepatitis end-stage diseases of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 112 routine patients altogether, wherein male 83 examples, women 29 examples; The oldest person 77 years old, the age reckling has only 18 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 9 courses of treatment altogether.
The therapeutic evaluation standard
Cure: sign is improved fully, various transference cures, and liver function is normal fully, and every test rating is normal fully, and the patient does not have any bad sensation, and diet is had a rest normal, and is in high spirits.
Produce effects: sign is significantly improved, and various symptoms disappear substantially, and liver function is near normal, and each index of correlation significantly changes, and the patient does not have obvious bad sensation, and diet is had a rest normal substantially, in high spirits.
Effectively: sign obviously changes, various doing well,improvings, and the liver function level promotes, and each index of correlation changes, and diet is had a rest and is taken a turn for the better, and spirit is better.
Invalid: sign and symptom do not have improvement, and liver function does not have the improvement sign, and each index of correlation does not have and changes or take a favorable turn and unusual.
Model case:
1, Liu, man, 42 years old, engineer.
Suffered from chronic hepatitis before 5 years, through long-term treatment, though liver function is approaching normal, the flushing flushing in zygomatic region continues the low grade fever.No tuberculosis medical history, pulmonary's perspective is normal, pain in the hepatic region, liver is little, can touch under the rib.Appetite is poor, and abdomen is acute to expand desire for hot drinks.Dizzy, tired, difficulty falling asleep, bad dream is easily waken up, and be a cup too low daytime, and the late into the night is anti-excited, and body weight significantly alleviates, loose stool, oliguria with yellow urine has foul smell, and ecchymosis appears in skin, deep red tongue, white and dry fur like powder gathered, left wiry and frequent pulse, right stringy pulse is slow.Take Chinese medicine composition of the present invention after 10 days, the low grade fever removes, and pain in the hepatic region alleviates gradually, and surplus disease all alleviates, took Chinese medicine composition of the present invention again 1 month, skin ecchymosis, hepatalgia disappear substantially, and symptom is greatly taken on a new look, the little basic recovery of hepatomegaly, continuous clothes Chinese medicine composition of the present invention 2 months, symptom all disappears, and on inspection, hepatomegaly is little, function is all normal.
2, Guo, man, 40 years old, workman.
Before 3 years, often feel pain in the hepatic region, chest pain, on inspection, be diagnosed as chronic hepatitis, symptomatic treatment is invalid.Look into before examining: liver a young waiter in a wineshop or an inn refer to, concurrent edema, and the face foot is all swollen, permanent current nose bleeding and be difficult to stop, body weight significantly alleviates, and breast side of body severe pain is held up back, day and night endlessly, vertigo and tinnitus, the tight cardiopalmus of gas, tired spontaneous perspiration, abdominal distention stomachache, soft stool, it is yellowish to urinate, and amount is many, and stringy and tense pulse is held concurrently puckery, yellowish fur and thick.Take Chinese medicine composition of the present invention after 10 days, pain is significantly alleviated, and day by day disappears in the water, took Chinese medicine composition of the present invention again 1 month, edema disappears entirely, and spirit is gradually shaken, two is just normal, surplus through looking into the only little finger of liver, no epistaxis takes place, continuous clothes Chinese medicine composition of the present invention 2 months, symptom all disappears, on inspection, liver returns to normal range, and liver function is normal.
3, poplar, man, 38 years old, cadre.Existing 7 years of the hepatitis course of disease does not touchingly heal, and day by day increases the weight of.The bimester before two orders, skin, face xanthochromia appear, the more normal little about 3cm of liver,, icteric index 80U, pain in the hepatic region, face foot edema, dizzy, appetite is poor, feel sick, vomiting, tired, ridge is sent out cold, spontaneous perspiration has creeping chill around umbilicus, and interventral play is expanded under the stomach, desire for hot drinks, big loose stool is thin, oliguria with yellow urine, enlarged tongue is tender, thick fur and be bored with relaxed and soft pulse.Take Chinese medicine composition of the present invention after 15 days, face foot edema significantly alleviates the hepatic region hypodynia, jaundice goes down, and takes Chinese medicine composition of the present invention again 1 month, and spirit is gradually shaken, the about 1cm of the check more preceding increase of liver, appetite increases, icteric index 25U, continuous clothes Chinese medicine composition of the present invention 1 month, symptom is greatly taken on a new look, and often has a meeting to unit, unconsciously tired, obeyed Chinese medicine composition of the present invention again 3 months, check liver size and every index are all normal, resume work.
4, Chen, woman, 37 years old, cadre.
The patient suffers from chronic hepatitis in nineteen sixty, and long-term treatment is invalid.Existing liver size is 1/3 of a normal liver, and liver function is poor, and hepatic region severe pain is dizzy, cardiopalmus, spontaneous perspiration, edema, arthralgia, poor appetite, normal vomiting, abdominal distention, face is sallow, the extremity and the tip of the tongue tremble, serious fear of cold, and leukocyte is low, subcutaneous often hemorrhage (purpura), big loose stool, turbid urine, the menstruation color is light, and amount is many, body of the tongue is light red and moisten, and tongue is light white thin greasy, deep-slow pulse and thin.Take Chinese medicine composition of the present invention after 15 days, spirit, appetite take a turn for the better, liver pain, cardiopalmus alleviate, took Chinese medicine composition of the present invention again 1 month, menstrual blood volume and subcutaneous hemorrhage reduce, and extremity and tremor linguae disappear, subcutaneous purpura is disappeared, the liver size is 2/3 of a normal liver,, continuous clothes Chinese medicine composition of the present invention 1 month, symptom is greatly taken on a new look, can participate in a conference and do not feel tired, it is ruddy that face has transferred to, and pain disappears substantially, obeyed Chinese medicine composition of the present invention again 4 months, check liver size and every index are all recovered normally, and energetic, symptom all disappears.
5, soup, man, 30 years old, peasant.
General weakness, loss of appetite appear in patient's conscious no clear and definite inducement before 5 years, simultaneously with right hypochondriac region pain, general weakness increases the weight of during work, could alleviate after must taking a load off one's feet 30 minutes, appetite obviously goes down, and detests oil, the time nauseating, abdominal distention arranged, be diagnosed as: chronic active hepatitis B, after giving Chinese herbs decoction and Western medicine (concrete title and metering not quite clear) and treating 3 months continuously, above-mentioned symptom once once disappeared.But drug withdrawal is recurrence again after 1 month, and is carrying out property and increases the weight of.Over nearly 1 year, shallow complexion is felt sick, vomiting, and appetite descends, and obviously becomes thin, and lethargy is depressed, hepatalgia, the often visible spontaneous oozing of blood of gingiva, two just are with blood, can not be engaged in general physical work.Take Chinese medicine composition of the present invention after 15 days, hepatalgia is alleviated, and the spontaneous oozing of blood of gingiva, two just is with blood significantly to alleviate, took Chinese medicine composition of the present invention again 1 month, appetite increases, and spirit takes a turn for the better, and has rosy cheeks, can be engaged in simple physical work, symptom is greatly taken on a new look, and obeys Chinese medicine composition of the present invention again 3 months, and symptom all disappears, can normally work, check: liver function is normal.
6, fourth, man, 33 years old, teacher.
Suffered from the acute icteric infectious hepatitis before 2 years, through curing commentaries on classics, nearly half a year, hepatalgia, jaundice is deepened, and companion's ascites is not though through treatment, have and take a turn for the better, liver function: icteric index 85 units, 10 milligrams of the red matter of gallbladder, glutamate pyruvate transaminase 640 units, turbid 16 units of zinc.When examining, appearance jaundice all over, color is secretly not bright, distension and fullness in the abdomen, shaking has the underwater sound, poor appetite, xerostomia is desire drink not, oliguria with reddish urine, the next day of stool once, spiritlessness and sparing of words, white and greasy fur, limit point matter is little red, the sliding number of pulse condition.Take Chinese medicine composition of the present invention after 15 days, hepatalgia is greatly alleviated, and jaundice alleviates gradually, took Chinese medicine composition of the present invention again 1 month, appetite increases, and spirit takes a turn for the better, liver function: icteric index 26 units, 4 milligrams of the red matter of gallbladder, glutamate pyruvate transaminase 230 units, turbid 13 units of zinc, ascites disappears substantially, and symptom is greatly taken on a new look, and it is surplus February to obey Chinese medicine composition of the present invention again, check: liver function is normal, and symptom all disappears.
7, Lee, woman, 18 years old.
The patient began ill toxicity anicteric hepatitis before 7 years, once certain hospital's hospitalization 1 year, also once took the treatment by Chinese herbs several months, did not all have to be clearly better, and the state of an illness repeatedly and increase the weight of the liver function persistent anomaly.When examining, liver function test: glutamate pyruvate transaminase 580U, the turbid 13U of Moschus moschiferous, the Moschus moschiferous wadding (+++), purpura appears in two lower limb and buttocks, and hepatalgia is felt sick sometimes, the urine frowziness, the complexion HUANGBAI(sic), fatigue and weak, food is received not fragrant, and tongue fur is white slightly, and pulse condition is heavy carefully unable.Take Chinese medicine composition of the present invention after 20 days, hepatalgia is significantly alleviated, receive the food still can, the check liver function: glutamate pyruvate transaminase 268U, the turbid 8U of Moschus moschiferous, the Moschus moschiferous wadding (+++), took Chinese medicine composition of the present invention again 1 month, tired symptom is got better, and food is received increase, two lower limb and buttocks purpura occurs and obviously reduce, continuous clothes Chinese medicine composition of the present invention 2 months, purpura, pain disappear substantially, and urine is normal, liver function: glutamate pyruvate transaminase is normal, the turbid 8U of Moschus moschiferous, Moschus moschiferous wadding (++), it is surplus April to obey Chinese medicine composition of the present invention again, symptom all disappears, and the every index of liver function is all normal on inspection.
8, the week certain, woman, 42 years old, peasant.
The patient because of abnormal liver function, through " liver is worn ", was diagnosed as chronic hepatitis http://www.haodf.com/jibing/ganya and does not heal before 11 years, and the state of an illness increases the weight of gradually.The self-induction fatigue and weak is depressed closely over the past half year, hepatalgia, waist soreness is felt sick, vomiting, appetite descends, yellow urine, liver function check: the turbid 16U of Moschus moschiferous, Moschus moschiferous wadding (++), albumins/globulins=4.0/3.0, glutamate pyruvate transaminase is normal, the liver size is about normal liver 1/2, lusterless complexion, and lip is light red dried slightly, deep pulse is counted accurately, and red tongue with thin fur is greasy.Took Chinese medicine composition of the present invention 15 days, hepatalgia is alleviated, and spirit is gradually shaken, continuous clothes Chinese medicine composition of the present invention 1 month, pain disappears substantially, the test of the turbid test of Moschus moschiferous, Moschus moschiferous wadding, glutamate pyruvate transaminase all recover normally, and the liver size is about normal liver 2/3, and it is surplus March to obey Chinese medicine composition of the present invention again, have rosy cheeks, energetic, above-mentioned symptom all disappears, and check liver size and function are all normal.
Five, therapeutic outcome:
In the 112 routine cases of being accepted for medical treatment,, wherein cure 43 examples through treatment in 9 months, produce effects 34 examples, effective 32 examples, invalid 3 examples, total effective rate reaches 97%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment hepatitis end-stage diseases patient.
Claims (7)
1. Chinese medicine composition for the treatment of hepatitis end-stage diseases is characterized in that: mainly contain following bulk drugs and form:
Pericarpium Citri Reticulatae 1～100 gram; Radix Curcumae 1～50 gram; Fructus Aurantii Immaturus 1～50 gram; Semen Raphani 1～50 gram; Radix Aristolochiae 1～40 gram; Folium Isatidis 1～150 gram; Rhizoma Cyperi 1～100 gram; Fructus Toosendan 1～50 gram; the Radix Linderae 1～50 gram; Massa Medicata Fermentata 1～150 gram; Semen Arecae 1～40 gram; Radix Scutellariae 1～40 gram; Rhizoma Coptidis 1～40 gram; Fructus Gardeniae 1～40 gram; Radix Rehmanniae 1～40 gram; Flos Chrysanthemi Indici 1～50 gram; Herba Taraxaci 1～50 gram; Radix Bupleuri 1～40 gram; Herba Houttuyniae 1～100 gram; Herba Scutellariae Barbatae 1～40 gram; Calculus Bovis 1～20 gram; Radix Arnebiae (Radix Lithospermi) 1～40 gram; Radix Puerariae 1～50 gram; Gypsum Fibrosum 1～50 gram; the Rhizoma Anemarrhenae 1～40 gram; Indigo Naturalis 1～30 gram; Herba Patriniae 1～50 gram; Fructus Canarii 1～40 gram; Rhizoma Smilacis Glabrae 1～50 gram; Fructus Forsythiae 1～40 gram; Flos Lonicerae 1～50 gram; Rhizoma Paridis 1～40 gram; the Radix Pulsatillae 1～50 gram.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the weight portion of each crude drug is:
Pericarpium Citri Reticulatae 50 grams; Radix Curcumae 20 grams; Fructus Aurantii Immaturus 30 grams; Semen Raphani 30 grams; Radix Aristolochiae 20 grams; Folium Isatidis 40 grams; Rhizoma Cyperi 30 grams; Fructus Toosendan 30 grams; the Radix Linderae 30 grams; Massa Medicata Fermentata 50 grams; Semen Arecae 20 grams; Radix Scutellariae 30 grams; Rhizoma Coptidis 20 grams; Fructus Gardeniae 20 grams; Radix Rehmanniae 25 grams; Flos Chrysanthemi Indici 20 grams; Herba Taraxaci 30 grams; Radix Bupleuri 30 grams; Herba Houttuyniae 30 grams; Herba Scutellariae Barbatae 30 grams; Calculus Bovis 1 gram; Radix Arnebiae (Radix Lithospermi) 20 grams; Radix Puerariae 30 grams; Gypsum Fibrosum 30 grams; the Rhizoma Anemarrhenae 20 grams; Indigo Naturalis 15 grams; Herba Patriniae 30 grams; Fructus Canarii 20 grams; Rhizoma Smilacis Glabrae 30 grams; Fructus Forsythiae 20 grams; Flos Lonicerae 30 grams; Rhizoma Paridis 15 grams; the Radix Pulsatillae 30 grams.
3. according to the described Chinese medicine composition of claim 1, wherein crude drug also has:
Radix Trichosanthis 1～50 gram, Mirabilitum crystallina 1～50 gram, Semen Cassiae 1～40 gram, Radix Sophorae Flavescentis 1～40 gram, Radix Et Rhizoma Rhei 1～30 gram, Folium Sennae 1～40 gram, Semen Pruni 1～30 gram, Semen Plantaginis 1～40 gram, Rhizoma Alismatis 1～40 gram, Herba Lysimachiae 1～50 gram, Rhizoma Polygoni Cuspidati 1～40 gram, Pericarpium Arecae 1～50 gram, Fructus Citri Sarcodactylis 1～50 gram, Bulbus Allii Macrostemonis 1～40 gram, Fructus Hordei Germinatus 1～50 gram, Fructus Setariae Germinatus 1～40 gram, Fructus Crataegi 1～40 gram, Endothelium Corneum Gigeriae Galli 1～30 gram, Rhizoma Corydalis 1～40 gram, Semen Persicae 1～30 gram, Flos Carthami 1～30 gram, Herba Leonuri 1～50 gram, Radix Salviae Miltiorrhizae 1～40 gram, Radix Achyranthis Bidentatae 1～40 gram, Olibanum 1～30 gram, Myrrha 1～30 gram.
4. according to the described Chinese medicine composition of claim 3, wherein the weight portion of each component is:
Radix Trichosanthis 30 gram, Mirabilitum crystallina 20 grams, Semen Cassiae 20 grams, Radix Sophorae Flavescentis 20 grams, Radix Et Rhizoma Rhei 20 grams, Folium Sennae 20 grams, Semen Pruni 20 grams, Semen Plantaginis 20 grams, Rhizoma Alismatis 20 grams, Herba Lysimachiae 30 grams, Rhizoma Polygoni Cuspidati 20 grams, Pericarpium Arecae 30 grams, Fructus Citri Sarcodactylis 20 grams, Bulbus Allii Macrostemonis 20 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Crataegi 15 grams, Endothelium Corneum Gigeriae Galli 20 grams, Rhizoma Corydalis 20 grams, Semen Persicae 15 grams, Flos Carthami 15 grams, Herba Leonuri 30 grams, Radix Salviae Miltiorrhizae 20 grams, Radix Achyranthis Bidentatae 20 grams, Olibanum 15 grams, Myrrha 15 gram.
5. according to claim 1,2,3 or 4 described any Chinese medicine compositions, it is characterized in that: can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
7. the application of the described any Chinese medicine composition of claim 1～6 in preparation treatment hepatitis end-stage diseases medicine.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102133314A (en) * | 2010-10-27 | 2011-07-27 | 宋爱民 | Chinese medicinal preparation for treating ulcerative colitis |
| CN103041341A (en) * | 2012-12-30 | 2013-04-17 | 青岛恒波仪器有限公司 | Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof |
| CN103356971A (en) * | 2013-08-02 | 2013-10-23 | 李平 | Traditional Chinese medicine composition capable of substantially improving human immunity and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102133314A (en) * | 2010-10-27 | 2011-07-27 | 宋爱民 | Chinese medicinal preparation for treating ulcerative colitis |
| CN102133314B (en) * | 2010-10-27 | 2012-02-22 | 宋爱民 | Chinese medicinal preparation for treating ulcerative colitis |
| CN103041341A (en) * | 2012-12-30 | 2013-04-17 | 青岛恒波仪器有限公司 | Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof |
| CN103356971A (en) * | 2013-08-02 | 2013-10-23 | 李平 | Traditional Chinese medicine composition capable of substantially improving human immunity and preparation method thereof |
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