CN101720786A - Clinical surgical instrument disinfectant - Google Patents
Clinical surgical instrument disinfectant Download PDFInfo
- Publication number
- CN101720786A CN101720786A CN200910229990A CN200910229990A CN101720786A CN 101720786 A CN101720786 A CN 101720786A CN 200910229990 A CN200910229990 A CN 200910229990A CN 200910229990 A CN200910229990 A CN 200910229990A CN 101720786 A CN101720786 A CN 101720786A
- Authority
- CN
- China
- Prior art keywords
- silicone oil
- disinfectant
- surgical instrument
- methyl
- stirring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of medical disinfectants and relates to a clinical surgical instrument disinfectant. The disinfectant is prepared by adopting the following steps of: getting 100ml of methyl silicone oil and adding 1g of chlorhexidine, 0.5g of polyhexamethylene guanidine and 0.5g of polyvinylpyrrolidone; stirring and dissolving to obtain a methyl silicone oil solution; getting 500ml of water, adding 5g of hypochlorite and 2g of sodium dodecyl sulfate, and stirring and dissolving to obtain an aqueous solution; adding the aqueous solution, the methyl silicone oil solution and 0.5g of polysorbates 80 into a hermetic container; and stirring under ultrasonication and uniformly mixing to obtain an emulsion. The disinfectant has the advantages of stable chemical property, safety, high efficiency and long duration time, and reduces the disinfection number of times of surgical instruments and the probability of surgical infections.
Description
Technical field
The present invention relates to a kind of clinical surgical instrument disinfectant, belong to the technical field of medical disinfectant.
Background technology
The disinfectant that uses is generally the aqueous disinfecting agent at present, and the retention time on operating theater instruments is shorter, has increased the sterilization number of times of operating theater instruments, simultaneously, has strengthened the probability of postoperative infection.
Summary of the invention
The present invention provides a kind of chemical property stable, safe and efficient in order to overcome the deficiency of above technical elements, longer duration, the sterilization number of times of minimizing operating theater instruments, the probability of minimizing postoperative infection.
The present invention realizes by following measure:
The present invention relates to a kind of clinical surgical instrument disinfectant, it is characterized in that adopting following steps to make:
(1) get methyl-silicone oil 100ml, add Chlorhexidine 1g polyhexamethylene guanide 0.5g, polyvinylpyrrolidone 0.5g, stirring and dissolving gets methyl-silicone oil solution;
(2) water intaking 500ml adds hypochlorite 5g, dodecyl sodium sulfate 2g, and stirring and dissolving gets the aqueous solution;
(3) with the Tween 80 of the above-mentioned aqueous solution, methyl-silicone oil solution and 0.5g, add in the airtight container, under handling, stirs ultrasonic, mix, get emulsion.
The clinical surgical instrument disinfectant of the invention described above, preferred, the frequency that described ultrasonic is handled is 20KHz～40KHz, power is 10-15KW.
Above-mentioned clinical surgical instrument disinfectant is mixed more fully in order to make emulsion, and the speed that stirs described in the step (3) is preferably 30-50 rev/min.
Methyl-silicone oil of the present invention has tasteless nontoxic, has physiology inertia, good chemical stability, electric edge and weather resistance, and range of viscosities is wide, and freezing point is low, and the flash-point height does not have bad reaction to operating theater instruments and human body, and safety is good.On the other hand, methyl-silicone oil has the advantages that hydrophobic performance is good, surface tension is little, can form the layer of even liquid film on operating theater instruments; The adhesion property of above-mentioned Huaihe River film and operating theater instruments is fine, adds the not volatile characteristics of methyl-silicone oil, can make methyl-silicone oil and be dissolved in the interior medicine of methyl-silicone oil to remain on for a long time on the operating theater instruments, makes operating theater instruments have the bactericidal property of long period.
Beneficial effect of the present invention is, it is stable to have chemical property, safe and efficient, and longer duration has reduced the sterilization number of times of operating theater instruments, has reduced the probability of postoperative infection.
Embodiment:
Embodiment 1
The clinical surgical instrument disinfectant of present embodiment, adopt following steps to make:
Get methyl-silicone oil 100ml, add Chlorhexidine 1g polyhexamethylene guanide 0.5g, polyvinylpyrrolidone 0.5g, stirring and dissolving gets methyl-silicone oil solution;
Water intaking 500ml adds hypochlorite 5g, dodecyl sodium sulfate 2g, and stirring and dissolving gets the aqueous solution;
With the Tween 80 of the above-mentioned aqueous solution, methyl-silicone oil solution and 0.5g, add in the airtight container, under handling, stirs ultrasonic, mix, get emulsion.The frequency that described ultrasonic is handled is 30KHz, and power is 10KW; The speed that stirs is 50 rev/mins.
Embodiment 2
The clinical surgical instrument disinfectant of present embodiment, adopt following steps to make:
Get methyl-silicone oil 100ml, add Chlorhexidine 1g polyhexamethylene guanide 0.5g, polyvinylpyrrolidone 0.5g, stirring and dissolving gets methyl-silicone oil solution;
Water intaking 500ml adds hypochlorite 5g, dodecyl sodium sulfate 2g, and stirring and dissolving gets the aqueous solution;
With the Tween 80 of the above-mentioned aqueous solution, methyl-silicone oil solution and 0.5g, add in the airtight container, under handling, stirs ultrasonic, mix, get emulsion.The frequency that described ultrasonic is handled is 40KHz, and power is 15KW; The speed that stirs is 30 rev/mins.
Test case 1
Clinical surgical instrument disinfectant of the present invention and glutaraldehyde disinfectant are used for operating theater instruments, and bactericidal effect compares, and the result is as follows:
| Gram-positive, negative bacterium | Ball purulence liver bacterium | Microspironema pallidum | Tulase | Brood cell's (tetanus, gangrene) | Hepatitis type B virus | AIDS virus | |
| Embodiment 1 | Killed in 15 minutes 100% | Killed in 15 minutes 100% | Killed in 15 minutes 100% | Killed in 25 minutes 100% | Killed in 30 minutes 100% | Killed in 30 minutes 100% | Killed in 30 minutes 100% |
| Embodiment 2 | Killed in 15 minutes 100% | Killed in 15 minutes 100% | Killed in 15 minutes 100% | Killed in 25 minutes 100% | Killed in 30 minutes 100% | Killed in 30 minutes 100% | Killed in 35 minutes 100% |
| Glutaraldehyde disinfectant | Killed in 25 minutes 100% | Killed in 25 minutes 100% | Killed in 25 minutes 100% | Killed in 50 minutes 100% | Killed in 50 minutes 100% | Killed in 50 minutes 100% | Killed in 60 minutes 100% |
Test case 2
After clinical surgical instrument carried out disinfection with clinical surgical instrument disinfectant of the present invention and glutaraldehyde disinfectant respectively, be positioned over indoorly, after 12 hours, still have the disinfectant liquid film with the clinical surgical instrument of disinfectant sterilization of the present invention, bacteria living is not seen on the surface.Do not have the disinfectant liquid film with the clinical surgical instrument after the glutaraldehyde disinfectant sterilization, there is the part bacteria living on the surface.
Claims (3)
1. clinical surgical instrument disinfectant is characterized in that adopting following steps to make:
(1) get methyl-silicone oil 100ml, add Chlorhexidine 1g polyhexamethylene guanide 0.5g, polyvinylpyrrolidone 0.5g, stirring and dissolving gets methyl-silicone oil solution;
(2) water intaking 500ml adds hypochlorite 5g, dodecyl sodium sulfate 2g, and stirring and dissolving gets the aqueous solution;
(3) with the Tween 80 of the above-mentioned aqueous solution, methyl-silicone oil solution and 0.5g, add in the airtight container, under handling, stirs ultrasonic, mix, get emulsion.
2. clinical surgical instrument disinfectant according to claim 1 is characterized in that: the frequency that described ultrasonic is handled is 20KHz～40KHz, and power is 10-15KW.
3. clinical surgical instrument disinfectant according to claim 1 is characterized in that: the speed that stirs described in the step (3) is 30-50 rev/min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102299905A CN101720786B (en) | 2009-11-30 | 2009-11-30 | Clinical surgical instrument disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102299905A CN101720786B (en) | 2009-11-30 | 2009-11-30 | Clinical surgical instrument disinfectant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101720786A true CN101720786A (en) | 2010-06-09 |
| CN101720786B CN101720786B (en) | 2012-02-08 |
Family
ID=42442819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102299905A Expired - Fee Related CN101720786B (en) | 2009-11-30 | 2009-11-30 | Clinical surgical instrument disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101720786B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178963A (en) * | 2011-04-13 | 2011-09-14 | 张英联 | Medical ultrasonic couplant and preparation method of couplant |
| US9723833B2 (en) | 2013-01-25 | 2017-08-08 | Kemira Oyj | Biocide composition and method for treating water |
| CN109907069A (en) * | 2019-03-25 | 2019-06-21 | 天津市郁峰化工有限公司 | A kind of hypochlorous acid thimerosal and preparation method thereof |
| CN114126585A (en) * | 2019-07-22 | 2022-03-01 | 汇恩斯株式会社 | Water-soluble disinfecting composition comprising chlorhexidine or its derivative with improved antibacterial durability and fiber type disinfectant comprising the same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19517463C2 (en) * | 1995-05-12 | 1997-09-18 | Degussa | Process for the algicidal treatment of water |
| BRPI0716573A2 (en) * | 2006-08-24 | 2013-11-05 | Mallard Creek Polymers Inc | Anionic Latex as a Career for Bioactive Components and Methods for Making and Using the Same |
-
2009
- 2009-11-30 CN CN2009102299905A patent/CN101720786B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178963A (en) * | 2011-04-13 | 2011-09-14 | 张英联 | Medical ultrasonic couplant and preparation method of couplant |
| CN102178963B (en) * | 2011-04-13 | 2012-10-10 | 张英联 | Medical ultrasonic couplant and preparation method of couplant |
| US9723833B2 (en) | 2013-01-25 | 2017-08-08 | Kemira Oyj | Biocide composition and method for treating water |
| CN109907069A (en) * | 2019-03-25 | 2019-06-21 | 天津市郁峰化工有限公司 | A kind of hypochlorous acid thimerosal and preparation method thereof |
| CN114126585A (en) * | 2019-07-22 | 2022-03-01 | 汇恩斯株式会社 | Water-soluble disinfecting composition comprising chlorhexidine or its derivative with improved antibacterial durability and fiber type disinfectant comprising the same |
| CN114126585B (en) * | 2019-07-22 | 2024-04-09 | 汇恩斯株式会社 | Water-soluble disinfectant composition comprising chlorhexidine or derivatives thereof with improved antibacterial durability, and fiber disinfectant comprising same |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101720786B (en) | 2012-02-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102406959B (en) | Liquid bandage containing povidone iodine and preparation method thereof | |
| CN101720786B (en) | Clinical surgical instrument disinfectant | |
| CN102480972A (en) | Solution Containing Hypochlorous Acid And Methods Of Using Same | |
| US20200260723A1 (en) | Method for treating a fluid with an antimicrobial solid | |
| CN103004897A (en) | Efficient biological bactericide | |
| CN113331186B (en) | Foam disinfectant and preparation method thereof | |
| CN108888758A (en) | Collagen gynaecologic washing lotion and preparation method thereof | |
| CN1883273A (en) | Active disinfectant germicide and method for preparing same | |
| ES2488141T3 (en) | Air cleaning filter comprising protein deactivating agent and a method for producing the same | |
| CN113527933A (en) | Viroid ferrite super-hydrophobic coating and preparation method thereof | |
| CN1347425A (en) | Antimicrobial polymeric compositions | |
| WO2008073822A1 (en) | Breastpump assemblies having an antimicrobial agent | |
| CN111418602A (en) | No-clean disinfectant and preparation method and application thereof | |
| CN101492560A (en) | Polyvinyl alcohol hydrogel releasing negative ion and method of producing the same | |
| CN108452370B (en) | Composite supermolecule hydrogel and preparation method thereof | |
| CN109699686A (en) | A kind of disinfectant for killing avian influenza virus | |
| CN115850733A (en) | Injectable nano clay hydrogel and preparation method and application thereof | |
| CN101755763A (en) | Disinfection composition for preventing and treating livestock and poultry breeding diseases and prepration method and application thereof | |
| CN112262846B (en) | Object surface disinfectant for high-grade biosafety laboratory and preparation method thereof | |
| CN1889829A (en) | Antimicrobial compositions comprising polymeric stabilizers | |
| CN113144177A (en) | Surface sterilization antiviral spray and preparation method and application thereof | |
| CN108721411A (en) | GSE antibacterial washing fluids and preparation method thereof | |
| CN111759805A (en) | Oral and facial sterilizing and antiviral spray and preparation method and application thereof | |
| WO2017193509A1 (en) | Bionic gynecological lotion and preparation method therefor | |
| CN214343617U (en) | Disinfectant space sterilizing machine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120208 Termination date: 20121130 |