CN1017189B - 一种血气分析仪冲洗液 - Google Patents

一种血气分析仪冲洗液

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Publication number
CN1017189B
CN1017189B CN 88107960 CN88107960A CN1017189B CN 1017189 B CN1017189 B CN 1017189B CN 88107960 CN88107960 CN 88107960 CN 88107960 A CN88107960 A CN 88107960A CN 1017189 B CN1017189 B CN 1017189B
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CN
China
Prior art keywords
liquid
proteolytic enzyme
vigour
instruments
flushing liquor
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Expired
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CN 88107960
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English (en)
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CN1039897A (zh
Inventor
练亦祥
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TANGSHAN WORKERS' HOSPITAL
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TANGSHAN WORKERS' HOSPITAL
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Priority to CN 88107960 priority Critical patent/CN1017189B/zh
Publication of CN1039897A publication Critical patent/CN1039897A/zh
Publication of CN1017189B publication Critical patent/CN1017189B/zh
Expired legal-status Critical Current

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  • Investigating Or Analysing Biological Materials (AREA)

Abstract

本发明涉及到一种通用于血液气体分析仪器的电极和仅器微型管道内壁的冲洗液,这种冲洗液由A、B两种液体组成,A液主要由氧化剂和蛋白水解酶组成,B液主要由表面活性剂和普通盐溶液组成,A、B两液配合使用可在仪器进样分析后及时除去电极上和仪器微型管道壁上吸附的血液蛋白质,以保证仪器迅速恢复稳定状态,延长电极和仪器的使用寿命。

Description

本发明属于一种通用于血液气体分析仪器的电极及仪器微型管道冲洗液。
在血气分析仪器进样分析后,要使用冲洗液除去吸附在电极和微型管道壁上的血液蛋白质,以保持仪器处于稳定状态,血气分析仪每年耗用大量的电极冲洗液。目前各国生产的血气分析仪使用的冲洗液比较混乱,洗涤效果不好,冲洗后仪器不稳定,易发生故障,并且各国生产的各个系列的电极其冲洗液不能互相取代使用,给医务分析工作者的操作造成许多麻烦。
本发明的目的在于提供一种通用型的血气分析仪器电极和微型管道冲洗液,能在短时间内除去电极和管道壁上吸附的血液蛋白质,它能与不同pH的缓冲定标液配合使用。适用于各种型号的血气分析仪电极的冲洗操作。
本发明涉及到的冲洗液由A、B两种溶液配合使用,A液主要由氧化剂和蛋白水解酶组成,B液主要由普通盐溶液和表面活性物质组成。A液组分中的氧化剂可以是重铬酸盐、次氯酸盐、迭氮化物等具有氧化性的盐类,蛋白水解酶可制成冷冻干燥的酶球保存,随时取用。B液组分中的表面活性物质可选择tri-to一类的表面活性剂,盐溶液可选用NaCl等高纯试剂。
本发明的冲洗液与目前国内外使用的冲洗液相比能及时除去吸附在分析仪器微型管道壁上和电极上的蛋白质、使仪器在三分钟内迅速恢复稳定状态,并维持仪器24小时开机,保持仪器的测试精度。本发明的冲洗液适用于各种类型的血气分析仪电极的冲洗操作,具有简单、方便、易保存和清洗效果好等优点。
实施例
A液:
次氯酸钠    50-100mole
重铬酸钠    5-15mg/l
迭氮钠    50-100mg/l
过滤后装小瓶,每瓶10ml,临用时加蛋白水解酶球1-2粒。
※蛋白水解酶球的制作:
1、取蛋白水解酶2-4g,溶于无苗去离子水20ml中,投入吸水性磁珠200粒,密封容器置-20℃冷冻48小时。
2、取出冻干的磁珠,用玻璃纸包封后再以黑纸包封一层,浸入60℃蜡液中封固,可存放一年。
B液:
NaCl    0.5-1.5%
tri-to    1-2ml/l
使用本发明的冲洗液冲洗电极时先将A液一小瓶加入蛋白水解酶球1-2粒,10分钟后即可使用,(A液加入蛋白水解酶球后在4℃冰箱最多可存放24小时)每日血气分析完毕后,取本发明的冲洗液A液同血样进样法吸入冲洗一次,如使用血气分析仪每日分析血样较少,则每分析一个血样,也要吸入A液冲洗一次血气分析仪,然后用B液维持仪器开机。

Claims (3)

1、一种血气分析仪冲洗液由A、B两种溶液组成,A液包括次氯酸钠50-100ml/l,重铬酸钠5-15mg/l,选氧钠50-100mg/l,蛋白水解酶10-40mg/l组成,用于血气分析血样后冲洗电极,B液由NaCl15-15g/l和rl-to 1-2ml/l组成,用于维持仪器开机。
2、根据权利要求1所述的血气分析仪冲洗液A液,其特征在于蛋白水解酶为冷冻干燥品,载体为吸水性磁珠。
3、一种血气分析仪冲洗液的制备方法,其特征在于A液中的蛋白水解酶应首先制成蛋白水解酶球,再加入A液中,蛋白水解酶球的制作方法为取蛋白水解酶2-4g,溶于无菌去离子水20ml中,投入吸水性磁珠200粒,密封容器置-20℃冷冻48小时,取出冻干的磁珠,用玻璃纸包封后再以黑纸包封一层,浸入60℃蜡液中封固可存放一年,使用时取出加入A液中。
CN 88107960 1988-11-15 1988-11-15 一种血气分析仪冲洗液 Expired CN1017189B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 88107960 CN1017189B (zh) 1988-11-15 1988-11-15 一种血气分析仪冲洗液

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 88107960 CN1017189B (zh) 1988-11-15 1988-11-15 一种血气分析仪冲洗液

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CN1039897A CN1039897A (zh) 1990-02-21
CN1017189B true CN1017189B (zh) 1992-06-24

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018519838A (ja) * 2015-07-15 2018-07-26 ザイムトロニクス エルエルシーZymtronix, Llc 自動バイオナノ触媒製造
CN106635440A (zh) * 2016-12-19 2017-05-10 青岛古高生物科技有限公司 一种凝血分析仪的清洗液

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