CN101716336A - Yikang capsule and production process thereof - Google Patents

Yikang capsule and production process thereof Download PDF

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Publication number
CN101716336A
CN101716336A CN200910223874A CN200910223874A CN101716336A CN 101716336 A CN101716336 A CN 101716336A CN 200910223874 A CN200910223874 A CN 200910223874A CN 200910223874 A CN200910223874 A CN 200910223874A CN 101716336 A CN101716336 A CN 101716336A
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vitamin
selenium
sod
ubiquinone
capsule
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CN101716336B (en
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袁锡贵
李金元
孙序元
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Tianjin Tianshi Life Resources Co ltd
TIENS GROUP CO Ltd
Tianjin Tiens Biological Development Co Ltd
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TIANSHI GROUP CO Ltd TIANJIN
Tianjin Tiens Biological Development Co Ltd
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Abstract

The invention relates to a Yikang capsule which is characterized in that a formula comprises the following components in parts by weight: 80-95 parts of carrot meal, 2-3 parts of vitamin C, 2-3 parts of vitamin E, 1-2 parts of selenium, 0.1-1 part of coenzyme q10 and 1-2 parts of SOD; a production process of the Yikang capsule comprises the following steps of: 1. sieving the carrot meal, the vitamin C and the vitamin E, and mixing the carrot meal, the vitamin C, the vitamin E, the selenium, the coenzyme q10 and the SOD; 2. filling by using a full automatic capsule filling machine; and 3. filling. The Yikang capsule has the advantages of remarkably improving the calcium absorptivity compared with like products, being suitable for being taken by people of all ages, particularly for middle-aged and old people, having stable production process conditions, and being suitable for large-scale industrial production.

Description

A kind of beneficial recovering capsule and production process thereof
(1) technical field:
The present invention relates to a kind of capsule and production process thereof, particularly a kind of beneficial recovering capsule and production process thereof.
(2) background technology:
Along with the aging of society, in western countries, the aggravation of social competition, survival pressure strengthens, and " subhealth state " state becomes puzzlement people's formidable enemy, has understood that at present Oxidation is the major reason of human catabiosis.
The antioxidant of human body has self synthetic, also has by food supply.Enzyme and non-enzyme antioxidant play crucial effects in protection owing in the kinetic peroxide injury.Additional antioxidant helps the motion body to be reduced the generation of free radical or quickens its removing, with side effect to free radical resisting, thereby it is all useful to common people and athletic health, possible delayed motion fatigue takes place and accelerates physical efficiency recovery, and it is better that older physical exertion person's ratio year the lighter takes antioxidant effect.
In order to prevent the oxidation of bad cholesterol (LDL), the rejuvenation that keeps blood vessel, prevention of arterial sclerosis, cerebral hemorrhage, cerebral infarction and cardiopathic generation and development, therefore demand developing a kind of antioxidation health food urgently, to guarantee that people can absorb enough materials with antioxidation in daily life.
(3) summary of the invention:
The object of the present invention is to provide a kind of beneficial recovering capsule and production process thereof, its calcium absorptivity obviously improves than like product, is fit to each age level people, especially takes in middle-aged and elderly people, and its production process conditional stability is fit to large-scale industrial production.
Technical scheme of the present invention: a kind of beneficial recovering capsule is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD; Its weight quota is than being Radix Dauci Sativae powder 80~95: vitamin C 2~3: vitamin E 2~3: selenium 1~2: ubiquinone 10 0.1~1: SOD 1~2.
A kind of production process of beneficial recovering capsule is characterized in that it being to be made of following steps:
(1) carrot powder, vitamin C, vitamin E are crossed 60~100 mesh sieves, and with Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD mixing 30-50 minute, mix homogeneously;
(2) use Autocapsulefillingmachine to fill;
(3) use automatic several bottling product lines, fill is product.
The health-care effect analysis of the related prescription of the present invention:
One, antioxidation
Antioxidation is not only a notion, can quantitative determination to organism antioxidative effect, as zoopery generally be take the antioxidant certain hour after, measure that ester matter peroxidating product malonaldehyde in the blood changes and liver homogenate in the vigor of superoxide dismutase SOD and glutathion peroxidase GSH-PX change.Judge antioxidative intensity and effect from the changing condition of above-mentioned two kinds of enzymes and MDA.Can not survey liver homogenate as human body, can measure the MDA in blood or the urine, and the SOD in the blood, GXH-PX judge the antioxidative effect.
Oxidant extremely Chinese scholars concern for a long time in the food; this be because 1. in the food antioxidant can protect food to avoid oxidative damage and rottenly 2. in human body alimentary canal, have antioxidation, 4. food-based some extract with antioxidation that prevents from can to play a role in other histoorgans of body after digestive tract generation oxidative damage from absorbing can be used as the treatment medicine.The mechanism of action of antioxidant comprises sequestration metal ion, removing free radical, cancellation singlet oxygen, removes oxygen, inhibited oxidation enzymatic activity etc.
Two, the vitamin E health-care effect is analyzed:
According to the Yang Xiaoguang researcher of Chinese Academy Of Preventive Medicine Research Institute Of Nutrition And Food Hygiene introduction: external expert of nineteen twenty-two finds that normally breeding of a kind of fat-soluble meals factor pair rat is essential.Nineteen twenty-four, this factor just was named as vitamin E.After zoopery in, scientists finds, the E if white mice is deficient in vitamin then the heart, liver and muscle deterioration and fertility can occur; The E if rat is deficient in vitamin then male permanent fertility femalely can not be cherished mature tire son, also have symptoms such as liver degeneration, myocardial abnormality simultaneously; Anemia, fertility, myocardial abnormality will appear in the monkey E that is deficient in vitamin.The eighties, medical experts find, if the mankind have lacked vitamin E then can cause hereditary and metabolic disease.Along with going deep into of research, the medical expert recognizes that again vitamin E has effect widely at aspects such as control cardiovascular and cerebrovascular disease, tumor, diabetes and other complication, central nervous system disease, locomotor disease, dermatosis.Vitamin E is important polyphenoils and a membrane stabilizer in the cell membrane.Vitamin e is keeping the normal mechanism and the metabolism of muscular tissue, and particularly supply of the energy during muscle contraction and calcium ion picked-up and release have important effect.Vitimin supplement E (400~1,600 iu/sky) can reduce by strenuous exercise or other situation and cause that free radical increases the damage to body.When being higher than the sea level, vitimin supplement E can prevent the reduction of motor capacity.Therefore, think the raising that helps sports achievement at the athlete's vitimin supplement E that is being higher than sea level training.The dosage of recommending replenish (d-alpha-tocopherol) vitamin E every day is: 400~800 ius.The use of vitamin E mainly contains following function
(1), the treatment atherosclerosis abroad reports, takes in vitamin e1 every day more than 00 milligram, can slow down light, in or the progress of severe coronary atherosclerosis.Every day vitimin supplement C or the multivitamin progress of coronary atherosclerosis that then can not slow down.
According to another report, take 00 milligram of vitamin E2 and vitamin A 90,000 units for the arteriosclerosis patient, symptoms such as 6 to 10 weeks back headaches, insomnia, dizzy, tinnitus can alleviate, and blood pressure drops, lipid cholesterol descend.
(2), treatment congestion cardiac insufficiency and angina pectoris to this class patient give every day 00 milligram to 400 milligrams of vitamin E2, exercise load is increased, angina pectoris disappears, and diuresis is arranged.
(3), the preventive and therapeutic effect experiment in vivo and vitro of tumor is shown that vitamin E has the control growth of tumour cell, reduce or delay the effect that in-vivo tumour takes place.The epidemic diseases data shows that also body vitamin E intake and tumor are negative correlativing relation.
For example, foreign study is found, can prevent the alopecia that the chemotherapeutics amycin causes with megavitamin E, and general consumption is 1600 milligrams of every days, and Time of Administration should begin preceding 5 to 7 days in chemotherapy.
(4), vitamin E and gynaecopathia are taken the vitamin E soft gelatin capsule and can be cured some women and place the hemorrhage or menorrhagia that occurs behind the intrauterine device.Method is: oral vitamin E100 milligram every other day, and 7 days was 1 course of treatment, general treatment gets final product 1 to 3 course of treatment.Other has bibliographical information, and vitamin E can be treated immune infertility, fertility and habitual abortion.
Three, the vitamin C health-care effect is analyzed:
Hypovitaminosis C can reduce the endurance exercise ability greatly.Vitimin supplement C can obviously reduce exercise induced oxidative stress.The safe dose of vitimin supplement C is 0.5~3.0 gram/sky.The dosage of recommending vitimin supplement C every day is 0.5~2.0 gram.Many people can replenish dimension C, but common people ate two " Xiao Bai sheets " in one day, replenished the dimension C of low dose.Can be abroad, a large amount of in recent years scientific researches all show: heavy dose of dimension C, just the dimension C more than 1000 milligrams has positive assosting effect at health field, such as:
1, the stress ability of energy enhance immunity cell can prevent and treat various acute and chronic infectious diseases or other diseases such as flu.
2, improve the particularly metabolism of cholesterol of fat and lipoid, prevents heart disease, the danger of lowering coronary heart disease.
3, promote the metabolism of middle tyrosine of aminoacid (amino acid foodstuff) (aminoacid product, aminoacid information) and tryptophan, effectively prolong cell and human body life-span.
4, owing to can promote the generation of colloid and hormone, the protection cell is avoided ray and is destroyed, and ties up the C level in the body and has significant positive correlation fertility.
5, can reduce the standardized death rate of various diseases, and more remarkable to male's (male's food) effect.
Four, selenic health-care effect analysis:
Selenium is one of essential trace element of humans and animals.Nineteen fifty-three Schwartz finds that Se can make rat exempt from the hepatic necrosis of meals, and to propose Se be a kind of trace element that body can not lack.China scientist studies the substantial connection that has that at first proposed Se and Keshan disease in 1973 through for many years collaborative, and has carried out a large amount of clinical intervention Journal of Sex Researchs, has obtained tangible result.Thereby affirmed that Se is the requisite a kind of trace element of human body, these work cause scholar's in the world extensive concern and certainly.WHO confirms that in 1973 selenium is the first kind (comprising iodine, zinc, copper, molybdenum, chromium, the ferrum) trace element of needed by human.Now selenic biological action and progress thereof are described below.
1 selenic molecular biological characteristic
A large amount of research data prompting both at home and abroad, Se has biological action widely, is bringing into play increasing effect in prevention Keshan disease and some cancer and slow down aging.The form of selenium in blood and tissue may be diversified, but mainly be that Se plays a role by being incorporated in the protein, Se is present in the protein with two kinds of forms, and a kind of is to exist with the dissociable factor, and another kind is that the form that combines with covalent bond with aminoacid exists.The Se that exists with first kind of form is more common in antibacterial, selenium in mammal is present in the protein with the form of covalent bond, wherein be mainly concerned with two aminoacid, be selenocystein (Se-Cys) and Selenomethionine (Se-Mys), the latter can replace the existence of methionine in protein, and Se-Cys mainly is catalytic oxidization-reduction reaction [3~5] only in the special function of proteinic specific site performance.
2 selenic biological functions
Selenium is the essential material of body, its topmost biological function is the important component that constitutes glutathion peroxidase (GSH-Px), catalytic reduction type glutathion (GSH) becomes oxidized form of glutathione (GSSG), makes deleterious peroxide become nontoxic hydroxylate.
H2O2 is decomposed under the catalysis of GSH-Px, thereby protection cell and do not organize and damaged by peroxide is particularly protected the film of cell and organelle, as mitochondrion, microsome, lysosomal film.Selenium and vitamin E all are antioxidants, have synergism between them.Selenium is that the mode with glutathion peroxidase works, and catalysis H2O2 resolves into H2O, the performance antioxidation, thus protection cell and tissue avoid being subjected to the infringement of peroxide.Vitamin E then is to stop unsaturated fatty acid to be oxidized to hydrous oxide, and in addition, selenium participates in the synthetic of ubiquinone.Someone thinks that selenium can also make deleterious metal such as inactivations such as arsenic, hydrargyrum in vivo.
3 selenium and body's immunity
The biological action of relevant Se proves that in the seventies it is the important component of glutathion peroxidase, and therefore, it has important role in the cell antioxidant system.Selenium then is one of focus of Recent study with the research of immunity, if when researcher finds that selenic intake is lower than optimal dose, can damage the growth and the function of body immune system, existing the selenium and the relation of immunity is introduced from the following aspects:
3.1 the effector lymphocyte of selenium and nonspecific immunity nonspecific immunity comprises macrophage, mononuclear cell and neutrophilic granulocyte, phagolysis is nonspecific immunity effector lymphocyte's a critical function with the microorganism that kills and wounds infection.Many studies confirm that, selenium can influence cytophagous disinfection vitality.People such as Wurgastuti have studied the Immune Effects of Selenium Supplement to the pregnancy period sow, find that selenium deficiency can obviously suppress the phagocyte killing activity, and selenium supplement then can significantly improve sow peripheral blood phagocyte killing activity.People such as Bendnarek carry out two all zooperies, and give calf intramuscular injection with the selenium of 5.75mg every day, and numeration of leukocyte obviously rises in the blood as a result, and nitroblue tetrazolium (NBT) positive cell number and phagocytic count all obviously increase (P<0.05).Selenium influences phagocytic function, and the cutter reason is clear as yet really, may be relevant with GSH-Px, remain further to be studied.
3.2 the main effects cell of selenium and specific immunity specific cellular immunity is T cell, NKT (NK) cell and K cell.The T cell subsets can be divided into complementary T (TH) cell (this type of cell is identification antigen and produces antibody), inhibition T (TS) cell (mainly being that B cell, macrophage and other T cell activity are played the negative regulation effect) and cytotoxicity (TC) cell (target cell and the tumor cell that infects played dissolving and lethal effect) again.Replenishing an amount of selenium can make humans and animals TC and NK cell activity obviously strengthen.People such as Kiremid-jian give the normal volunteers of selenium Selenium Supplement (200 μ g/d), and the tumor cytotoxic activity of 8 week back peripheral blood TC mediations increases by 118%, and the NK cytoactive increases by 8263%.People such as ROy replenished for 8 weeks for old and feeble rat with 2.0mg selenium/kg, and the tumor killing cell activity of Tc cell is brought up to the not level of the young rat of selenium supplement as a result.But selenium is not also understood the regulating action mechanism of Tc cell, may can make interleukin II (IL-2) expression of receptor on the cell membrane strengthen relevant with selenium supplement, also might be that selenium has influenced transmembrane potential or the conduction of intracellular signal, thereby influence the propagation and the differentiation of Tc cell.In addition, selenium can also make induced T lymphocyte (Ti) and Tc ratio descend, and TH quantity raises.There is remarkable positive correlation in the serum selenium level with CD4+T cell number and CD4+/CD8+ ratio.Above-mentioned these explanation selenium can be regulated cellular immunization, raise immunity.
Selenium is in the Niu Zuowei selenium supplement experiment that lacks critical level 3.3 people such as selenium and humoral immunization Markimur take in abundant with vitamin E, and injection haemophilus H.somus.Early stage in Selenium Supplement, the selenium supplement group changes with the matched group antibody titer does not have obviously increase, but the report that has is in contrast.Selenium is few to the research of immunoglobulin influence, and the result is also inconsistent, and selenium does not appear in the newspapers as yet to the humoral immunization mechanism of action.This respect should further be furtherd investigate.
In a word, selenium deficiency can influence immune various aspects, and selenium supplement can make cellular immunization, humoral immunization, non-specific immunity improve.One of mechanism of action may be the increased activity that contains selenic GSH-PX, thereby can reduce the function of the accumulation enhance immunity cell of immunocyte endoperoxides lipid.
4 human selenium deficiency and requirements thereof
Scarce selenium can cause the muscular dystrophy of sheep, particularly skeletal muscle and myocardium color shoals, and is called white muscle disease.Also find white muscle disease in other domestic animal and wild animal, myocardial necrosis widely can take place in animal.Simple lack selenium and vitamin E just often, the birds retardation of growth, feather is not normal, fibrosis of pancreas.Lack selenic rat and dysplasia, dysgenesia and cacospermia can occur.
The Keshan disease of China is relevant with the endemicity selenium deficiency, and the part rural area on ground such as Heilungkiang, Jilin, Liaoning, Shaanxi, Gansu, Shanxi, Shandong, Hebei, Henan, Sichuan, Yunnan, Tibet, Ningxia, Hubei all has this disease popular.Show that now the staple food grain in Epidemic of Keshan Disease district, child's hair, Blood Selenium content all are lower than non-popular district.GSH-PX's in the popular district whole blood is active low, and urine selenium load is tested and lacked selenium in the resident's body that also shows popular district.Certainly the selenium Excessive Intake also can cause poisoning, shows as the hair drying, easily crisp, eyebrow, beard, armpit hair, pubes come off, and piptonychia, first become fragile, white point appears in the first face and longitudinal grin, the fracture of first face, acroanesthesia and symptoms such as tic, paralysis.
Selenic requirement and quantity delivered: China's Keshan disease result of study is thought: the minimum selenium intake of prevention Keshan disease is μ g every days 17, can keep the constant level of high vigor of blood plasma GSH-PX when taking in 48.3 μ g every day.Meals selenium intake every day is advisable with 50~250 μ g.
The present Research of the relevant selenium exploitation of 5 present China
Because selenium is the important component part of removing the glutathion peroxidase of peroxide and free radical, it is a kind of powerful antioxidant, have important physical, pharmacology and clinical meaning, and selenium also has the effect that suppresses some cancerous cell, excites immunoglobulin, enhancing human body immunity power.Therefore, it has anticancer, anti-cancer and anti-treating the liver and cardiovascular diseases, and has tangible antidotal effect.So the relation of selenium and human health and disease and application thereof are subject to people's attention day by day.Discover both at home and abroad that in recent ten years low selenium area is tangible negative correlation with the tumor mortality rate, zoopery shows that trace element-selenium can suppress the development of cancers such as liver, mammary gland, colon, skin.In Qidong, Jiangsu county, China hepatocarcinoma district occurred frequently, research worker has been done crowd's Selenium Supplement intervention experiment, observes 4 years, found that hepatocarcinoma HIF Selenium Supplement after the hepatocarcinoma incidence rate lower more than 2 times (P<0.05) than matched group.Selenium also has the effect of significant protection liver; 20,000 people observe with containing selenium Sal in Qidong county; with 190,000 people in contrast, incidence of hepatitis rate decline 1.7-3 times (P<0.05) as a result, 450,000 people's expansion experimental results show that selenium supplement has the effect of obvious inhibition first, hepatitis B.Domestic how tame hospital is with Xi Likang (containing the selenium yeast sheet) treatment myocarditis, and cure rate reaches 90%-93%, do not add selenium then cure rate be 60%-69%, add selenium treatment coronary heart disease total effective rate and reach 93%-95%, do not add selenium then total effective rate be 73%.Beijing air force general hospital reaches 96.63% with Xi Weikang sheet treatment rheumatic arthritis 3000 many cases total effective rates.
Selenium is the essential composition of body antioxidant system constituent glutathion peroxidase, and suitably selenium supplement can improve glutathione peroxidase activity, thereby improves the oxidation resistance of body.Someone reports to swimmer's Selenium Supplement every day 100~150 micrograms can reduce the body lipid peroxidating, and the prompting selenium supplement may be useful to endurance exercise person.The selenium supplement dosage of suggestion is micrograms every days 100~250.
Five, the beta-carotene health-care effect is analyzed:
Nineteen twenty-nine, Moore found through experiments, and can significantly improve vitamin a level in the body behind the rat supplementary feeding beta-carotene of the A that is deficient in vitamin, thereby confirm that carotene can be converted into vitamin A in vivo, the effect of performance vitamin A is so be called provitamin A again.
Beta-carotene is the precursor of vitamin a, has the function of removing free radical, so the oxidative stress of beta-carotene during to motion has protective effect.The beta-carotene magnitude of recruitment of recommending is every day 25,000-100,000 iu.
Beta-carotene is a kind of green and yellow vegetable of extensively being present in, the natural carotenoid in the fruit.Beta-carotene is joined end to end by the two keys of 4 isoprene and forms, and belongs to the tetraterpenes chemical compound, and 1 β-purple trailing plants ketone ring is respectively arranged at the two ends of molecule, and center burst can produce 2 vitamin A molecules, and conjugation between a plurality of pairs of keys and the two key is arranged.Molecule has long conjugated double bond chromophore, thereby has the character of light absorption, makes its displaing yellow.Beta-carotene mainly contains alltrans, 9-cis, 4 kinds of forms of 13-cis and 15-cis.Kind of isomer was water insoluble surplus beta-carotene had 20, was slightly soluble in vegetable oil, in aliphatic and aromatic hydrocarbon medium dissolubility was arranged, and was soluble in chloroform, and oxidation reaction easily takes place when illumination and heating unstable chemcial property.
Beta-carotene can be by chemosynthesis, plant extract and 3 kinds of method productions of microbial fermentation, be divided into chemosynthesis beta-carotene and natural beta-carotin two big classes according to mode of production difference, great majority are chemicals at present, because natural beta-carotin has good anti-chromosomal aberration, protective effect on cancer risk and stronger physiologically active, the price of natural beta-carotin are 2 times of chemicals.Beta-carotene has the title of vitamin a source, is a kind of important human body physiological function active substance.In recent years, relevant beta-carotene is to the research Showed Very Brisk of human body effect.Studies confirm that in a large number; the many biological functions and the human health of beta-carotene have substantial connection; it is at antioxidation, detoxifcation, anticancer, angiocardiopathy preventing, and the physiological action of preventing and treating cataract and the liver protecting aspect is confirmed and be applied to prevention and treatment of diseases more and more.The beta-carotene of synthetic is applied in food more in the past, in the fields such as cosmetics and health product.Continuous development along with toxicology and analytical technology, studies show that: although the synthetic beta-carotene purity of chemical method is higher relatively, production cost is low, but product mixes a small amount of toxic chemical substance easily, the chromosome mutation of causing and carcinogenesis are arranged, and compare assimilation effect with natural beta-carotin too poor; And natural beta-carotin has the anti-cancer and cancer-preventing effect, does not have carcinogen, so improve constantly the natural extract beta-carotene status of will being active along with understanding in market.But because the liposoluble character of beta-carotene makes its range of application be subjected to considerable restraint.Some research strengthens the water solublity of beta-carotene by saponification and emulsive method, but this mode time is long, and the stability of β-Radix Dauci Sativae is had considerable influence, and cost is also higher.The extraction of natural beta-carotin, the organic solvent that exists at present methods that adopt more, the residue problem of toxic solvent is limiting the use of extracting product always, brings more food safety and problem of environmental pollution.And relevant research report is also arranged about the extraction of water miscible beta-carotene, but the beta-carotene water solublity is relatively poor, usually also will be when extracting by the effect of enzyme, so the cost height, application is poor.Compare with conventional extracting mode, ultrasonic extracting method has easy, extraction ratio height, characteristics such as operating time weak point.
Six, the health-care effect analysis of ubiquinone 10:
But the coenzyme Q10 synthetic a kind of key substance of keeping human body health that is human body self, after human general 25 years old, synthesis capability progressively descends, and coenzyme Q10 has repair cell, the effect that improves immunocompetence and slow down aging is that other materials are irreplaceable, therefore be referred to as by American-European scientist, physician " magical coenzyme Q10 ", suggestion is when the synthetic deficiency of human body self, and is healthy to keep by exogenous additional coenzyme Q10, slow down aging.
The most concentrated place of human body coenzyme Q 10 is heart, liver, kidney and pancreas, and when intravital coenzyme Q10 level dropped to a certain degree, the function of these internal organs just began to weaken.Simultaneously, coenzyme Q10 also is a kind of super antioxidant and street cleaner, can prevent the infringement of the radical pair cell that produces in fierce movable and conversion process of energy, and delay body aging; Because the pivotal role of coenzyme Q10 in the energy production process, it can also significantly improve energy and endurance.
Because the mystery effect and the irreplaceability of coenzyme Q10, developed countries such as America and Europe, Japan have the people that coenzyme Q10 analogy is taken for " sunlight of life and grain " everyday, and the content of human body coenzyme Q 10 as detection with weigh whether healthy important indicator.
Ubiquinone is the essential composition that will use all cells of oxygen in the body, because it is the electron transit mediator of the oxidative phosphorylation respiratory chain in the energy-producing process of material oxidation, the demand of energy increases greatly in the motion, so ubiquinone 10 can reduce human heart and the muscle free radical generates.For keeping healthy people, the recommendation use amount of ubiquinone is 30 milligrams of every days, if with treating various diseases, employed amount will be higher than this dosage.
Clinical testing data of the present invention:
1, Tang * *, the man, 71 years old, retired associate professor, arteriosclerosis for many years, long-term treatment is invalid, is short of physical strength, tired, asthma looks wane and sallow.Through taking described beneficial recovering capsule, two of every days, symptom has been clearly better after two months, continues edible half a year, and 2 of every days, health is clearly better, and muscle power heightens, and braces up, and reading revises the draft far into the night, and also not bitterly, spirit is also fine for head.After continue again to take.
2, Feng * *, woman, 61 years old, this patient's atherosclerotic occlusive disease because of the right foot of no obvious inducement sense before 20 days send out cool, be afraid of cold, pain, through edible described beneficial recovering capsule, two of every days, just obviously take effect after one month, both feet become numbness by imperception almost consciousness, and body temperature is reduced to normally, nasal obstruction, watery nasal discharge symptom take a turn for the better, continue to eat, numbness becomes pain, and above-mentioned symptom all disappears after 1 year, and can go shopping, go going window-shopping of several inside and outsides alone inside the city.
3, the king * *, the man, 48 years old, the cool fiber crops of extremity, listless and aching existing more than 1 year recently more very, also can tumble sometimes on foot.Take described beneficial recovering capsule upon somebody's introduction, 4 of every days, after three months, waist lower limb numbness alleviates, and sensation has been walked also energetically.After continue again to take.
4, pay * *, the woman, 52 years old, mentality and flag appearred before 3 years, and palpation body surface tremulous pulse such as temporo tremulous pulse, radial artery, brachial artery etc. can find to broaden, elongated, anfractuosity and hardening, since beginning to take described beneficial recovering capsule, 4 of every days, take one month after, muscle power is clearly better, again do not have uncomfortable sensation, and I feel that energy is more abundant now.
5, old * *, man, 65 years old, retired veteran cadre.The dullness area broadening of presternum aorta posterior is found in percussion when hospital's health check-up; Hyperfunction and the band metal tone of second sound of aortic area, and systolic murmur is arranged.Systolic blood pressure raises, pulse pressure broadening, and the radial artery palpation can similar irregular-rapid pulse.The visible aortic knob of X ray examination protrudes to the upper left side, aortectasia and distortion, and the calcinosis shadow is through taking described beneficial recovering capsule in the speckle of visible sometimes lamellar or arcuation, symptom obviously alleviates, and after continuing to take 2 months, symptom all disappears before, energetic, appetite increases.The back requires to continue to take.
6, open *, man, 55 years old, workman.Normal sense lumbago and skelalgia, myasthenia of limbs, symptoms such as dizzy, headache and faintness.Take described beneficial recovering capsule upon somebody's introduction, 4 of every days, after 2 months, conscious lumbago and skelalgia sx, after continuing to take 4 months, the cramp transference cure, the mental status is clearly better.The back requires to continue to take.
7, Lee * *, woman, 56 years old, peasant.Symptoms such as normal sense dyspepsia, intestinal hypotension, constipation and stomachache.Be diagnosed as superior mesenteric atherosclerosis, through taking described beneficial recovering capsule, two of every days, after 2 months, constipation stomachache alleviates, and appetite increases, after continue again to take.
8, poplar * *, woman, 51 years old, often be sore waist and aching in the waist and the back, weak on his pins, lower limb are sent out cold, numbness and intermittent claudication, gastrocnemius numbness, pain take place so that spasm when promptly walking, the back of having a rest disappears, and occurs again when going further, and it is atherosis to go to hospital to be diagnosed as artery of extremity, after take described beneficial recovering capsule upon somebody's introduction, 6 of every days, take after two months, pain relief continues to take, after 1 year, waist is not sour, and legs and feet are not numb yet.
Superiority of the present invention and beneficial effect are: (1) the present invention adopts vitamin E powder, selenium, and the carotene ratio is suitable, and collaborative antioxidation is arranged, arteriosclerosis, oxygen lack resistant function is taken the no GI irritation in back; And behind the dress capsule of granulating, can effectively reduce the drug effect loss, after taking, capsule is disintegrate under one's belt, discharges granule grain specific surface area and enlarges markedly, and increases with the intestinal contact area, and easily attached on the intestinal wall, excrete required time lengthening, absorbance obviously improves than other oxidation resistant product; (2) add ubiquinone and SOD in prescription, the two is promoting can to bring into play synergistic function aspect the antioxidation, and antioxidation is remarkable; (3) in prescription, add vitamin and mineral, both can promote the absorption of effective ingredient, have the effect of keeping the normal physiological metabolism, promoting anti-hypoxia again, be particularly suitable for middle-aged and elderly people and take; (4) its production process through fully pulverizing, mix, wherein is unfavorable for above raw material oils and fats and the phlegmatic temperament pulverized to make it go for the capsule filling process with abundant absorption, and used stable process conditions is fit to large-scale industrial production.
(4) specific embodiment:
Embodiment 1: a kind of beneficial recovering capsule is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element; Its weight quota is than being Radix Dauci Sativae powder 92: vitamin C 2: vitamin E 2: selenium 1: ubiquinone 10 1: SOD 2.
A kind of manufacturing process of beneficial recovering capsule is characterized in that it being to be made of following steps:
(1) carrot powder, vitamin C, vitamin E are crossed 60 mesh sieves, according to the above ratio Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element are mixed 50 minutes mix homogeneously;
(2) use Autocapsulefillingmachine to fill, red white capsule, loading amount is 0.4g;
(3) use automatic several bottling product lines, fill is 150 every bottle, the product that every case is 80 bottles.
Embodiment 2: a kind of beneficial recovering capsule is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element; Its weight quota is than being Radix Dauci Sativae powder 93: vitamin C 2: vitamin E 2: selenium 1: ubiquinone 10 1: SOD 1.
A kind of manufacturing process of beneficial recovering capsule is characterized in that it being to be made of following steps:
(1) carrot powder, vitamin C, vitamin E are crossed 100 mesh sieves, according to the above ratio Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element are mixed 30 minutes mix homogeneously;
(2) use Autocapsulefillingmachine to fill, red white capsule, loading amount is 0.4g;
(3) use automatic several bottling product lines, fill is 150 every bottle, the product that every case is 80 bottles.
Embodiment 3:
A kind of beneficial recovering capsule is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element; Its weight quota is than being Radix Dauci Sativae powder 92: vitamin C 2: vitamin E 2: selenium 1: ubiquinone 10 1: SOD 2.
A kind of manufacturing process of beneficial recovering capsule is characterized in that it being to be made of following steps:
(1) carrot powder, vitamin C, vitamin E are crossed 80 mesh sieves, according to the above ratio Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element are mixed 40 minutes mix homogeneously;
(2) use Autocapsulefillingmachine to fill, red white capsule, loading amount is 0.4g;
(3) use automatic several bottling product lines, fill is 150 every bottle, the product that every case is 80 bottles.

Claims (5)

1. a beneficial recovering capsule is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD; Its weight quota is than being Radix Dauci Sativae powder 80~95: vitamin C 2~3: vitamin E 2~3: selenium 1~2: ubiquinone 10 0.1~1: SOD 1~2.
2. according to the said a kind of beneficial recovering capsule of claim 1, it is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element; Its weight quota is than being Radix Dauci Sativae powder 92: vitamin C 2: vitamin E 2: selenium 1: ubiquinone 10 1: SOD 2.
3. according to the said a kind of beneficial recovering capsule of claim 1, it is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element; Its weight quota is than being Radix Dauci Sativae powder 93: vitamin C 2: vitamin E 2: selenium 1: ubiquinone 10 1: SOD 1.
4. according to the said a kind of beneficial recovering capsule of claim 1, it is characterized in that prescription is Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD element; Its weight quota is than being Radix Dauci Sativae powder 92: vitamin C 2: vitamin E 2: selenium 1: ubiquinone 10 1: SOD 2.
5. the production process of a beneficial recovering capsule is characterized in that it being to be made of following steps:
(1) carrot powder, vitamin C, vitamin E are crossed 60~100 mesh sieves, and with Radix Dauci Sativae powder, vitamin C, vitamin E, selenium, ubiquinone 10 and SOD mixing 30-50 minute, mix homogeneously;
(2) use Autocapsulefillingmachine to fill;
(3) use automatic several bottling product lines, fill is product.
CN2009102238742A 2008-12-02 2009-11-25 Yikang capsule and production process thereof Active CN101716336B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102441161A (en) * 2010-10-15 2012-05-09 胥永贵 Composite fat-soluble antioxidant
CN108450958A (en) * 2018-02-02 2018-08-28 昆明朗盛生物科技有限公司 A kind of application of selenium-rich composition and preparation
CN111374280A (en) * 2018-12-28 2020-07-07 江苏维乐益生食品科技有限公司 Full-vitamin carrot powder and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102441161A (en) * 2010-10-15 2012-05-09 胥永贵 Composite fat-soluble antioxidant
CN108450958A (en) * 2018-02-02 2018-08-28 昆明朗盛生物科技有限公司 A kind of application of selenium-rich composition and preparation
CN111374280A (en) * 2018-12-28 2020-07-07 江苏维乐益生食品科技有限公司 Full-vitamin carrot powder and preparation method thereof

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