CN101708294B - Medicinal composition for treating dermatosis chronic disease and preparation method thereof - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating a skin chronic disease, which is characterized by comprising the following medicaments in part by weight: 2 to 4 parts of vernonia anthelmintica, 1 to 2 parts of sambucus adnata, 3 to 5 parts of sophora alopecuroides, 4 to 6 parts of lightyellow sophora root, 5 to 7 parts of giant knotweed, 3 to 5 parts of cortex dictamni, 2 to 4 parts of coix seed, 1 to 2 parts of plantain seed and 1 to 2 parts of gordon euryale seed. The Chinese medicinal composition is prepared by adding water into the medicaments and decocting themedicaments. The Chinese medicinal composition is a pure Chinese medicinal preparation without hormone or preservative. After being applied, the Chinese medicinal composition takes effective after 30minutes and relieves itching the same day for a patient having quick response, and relieves itching in 2 days for a patient absorbing slowly, and has quick response without relapse. The Chinese medicinal composition has the effects of protecting skin, resisting allergy, diminishing inflammation, sterilizing, detoxifying and quickening blood, subsidising roseola (urticaria and wheal), promoting metabolism and normally repairing cells and rapidly recuperating the skin.

Description

A kind of pharmaceutical composition for the treatment of dermatosis chronic disease and preparation method thereof

Technical field

The present invention relates to the dermatosis chronic disease medicine, especially at various treating for skin disease medicines that allergic constitution caused.

Background technology

Current people in work and study because competitive strong, stress is excessive, cause the human endocrine imbalance disorderly, obstacle appears in metabolism, all can cause allergic constitution, allergic constitution sucks anaphylactogen, eat anaphylactogen, inject anaphylactogen, the generation of allergic dermatitis all can be brought out in contact allergy source etc., and cause violent pruritus, the scorching hot flushing of skin, erythema appears simultaneously, dermatosis symptoms such as welt, anaphylaxis dermatosis is also referred to as abnormality or reactive disorder, be modal in the dermatosis also be the most complicated disease, common is because quantity is many, be found in any age, be on the basis of the body intrinsic factor of complexity and extraneous factor due to tardy paraphilia reaction.

The western medical treatment anaphylaxis dermatosis is mainly with a large amount of anti-resistance amines, the effect of relief of symptoms is just temporarily played in the application of hormone, and side effect is very big, to infant, child's growth has very big influence especially, and dermatosis pruritus patient is by the hormone medicine relief of symptoms in each outbreak repeatedly year in year out, make body immunity low day by day, the very painful so that state of an illness is shown effect repeatedly, and delay is difficult, becomes the dermatosis persistent ailment.

The traditional Chinese medical science adopts outer wiping for oral administration usually on treatment allergic skin persistent ailment, reach and improve body constitution, strengthen self immunity of organisms by regulating human endocrine and metabolism, reduces the purpose of outbreak or healing.Thereby Chinese medicine side effect aspect the treatment allergic dermatitis is littler and relapse rate is lower.

Summary of the invention

The object of the present invention is to provide a kind of treatment dermatosis persistent ailment, can be antipruritic rapidly, side effect is little, Chinese medicine composition composition formula that relapse rate is low and preparation method thereof.

Chinese medicine composition composition formula of the present invention is characterized in that being made up of the medicine of following weight part ratio: Caulis Vernoniae andersonii 2-4 part, Herba Sambuci Adnatae 1-2 part, Herba Sophorae alopecuroidis 3-5 part, Radix Sophorae Flavescentis 4-6 part, Rhizoma Polygoni Cuspidati 5-7 part, Cortex Dictamni 3-5 part, Semen Coicis 2-4 part, Semen Plantaginis 1-2 part, Semen Euryales 1-2 part.

The preparation of drug combination method of this treatment dermatosis chronic disease is with Caulis Vernoniae andersonii 2-4 part, Herba Sambuci Adnatae 1-2 part, Herba Sophorae alopecuroidis 3-5 part, Radix Sophorae Flavescentis 4-6 part, Rhizoma Polygoni Cuspidati 5-7 part, Cortex Dictamni 3-5 part, Semen Coicis 2-4 part, Semen Plantaginis 1-2 part, Semen Euryales 1-2 part was directly soaked 20-30 minute, decocted then 30 minutes, and decocted after-filtration, remove slag, extracting solution continues to employ.

The main component of each component is as follows in the treatment dermatosis chronic disease pharmaceutical composition of the present invention:

1, Caulis Vernoniae andersonii: contain steroidal, Saponin, neat big and heavy stone fruit acid, coumarin, alkaloid etc.;

2, Herba Sambuci Adnatae: contain choline, sterol compound, flavonoid aminoacid etc.;

3, Herba Sophorae alopecuroidis: contain flavonoid, aminoacid, phenols, anthraquinone, tannin etc.;

4, Radix Sophorae Flavescentis: contain matrine, oxymatrine, Flos Sophorae alkali, flavonoid etc.;

5, Rhizoma Polygoni Cuspidati: contain anthraquinone glycoside and free quinone, emodin, tannin etc.;

6, Cortex Dictamni: contain tinea alba lactone, Cortex Dictamni alkali, sitosterol, trigonelline, obacunonic acid etc.;

7, Semen Coicis: fatty oil, protein, aminoacid, triterpenoid etc.;

8, Semen Plantaginis: contain polysaccharide cement lymphatic temperament, succinic acid, the fast cry of certain animals of gland, choline etc.;

9, Semen Euryales: starch-containing, protein, fatty oil, calcium, phosphorus, ferrum, riboflavin etc.

The modern pharmacological research prompting: Caulis Vernoniae andersonii, Herba Sophorae alopecuroidis, Herba Sambuci Adnatae and Rhizoma Polygoni Cuspidati all have the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, Cortex Dictamni, Radix Sophorae Flavescentis all have clearing heat and expelling damp, the parasiticidal effect of pain relieving, Semen Coicis, Semen Euryales, Semen Plantaginis have the effect of heat clearing away and eliminating dampness by diuresis, eliminating impediment pain relieving, clearing away heat and discharging pus.

Treatment dermatosis chronic disease pharmaceutical composition of the present invention is a medicine for external use, make a kind of liniment, wipe the examination observation through animal skin and inventor's body part skin, applying medicinal lotion or ointment, any toxicity does not appear in skin in back 24 hours, avirulence composition and contemporary toxicology prove deleterious medical material in each prescription, do not have eighteen incompatible medicaments, nineteen medicaments of mutual restraint incompatibility in the prescription, the flavour of a drug consumption does not surpass the drug standard regulation.

Concrete real-time mode

Embodiment 1, get Caulis Vernoniae andersonii 200g, Herba Sambuci Adnatae 100g, Herba Sophorae alopecuroidis 300g, Radix Sophorae Flavescentis 400g, Rhizoma Polygoni Cuspidati 500g, Cortex Dictamni 300g, Semen Coicis 200g, Semen Plantaginis 100g, Semen Euryales 100g.

More than nine flavors, medical material directly adds water 8L and soaked 20-30 minute, decocts then 30 minutes, decocts after-filtration, removes slag, extracting solution continues to employ.

Embodiment 2, get Caulis Vernoniae andersonii 400g, Herba Sambuci Adnatae 500g, Herba Sophorae alopecuroidis 600g, Radix Sophorae Flavescentis 600g, Rhizoma Polygoni Cuspidati 600g, Cortex Dictamni 500g, Semen Coicis 400g, Semen Plantaginis 200g, Semen Euryales 200g.

More than nine flavors, medical material directly adds water 15L and soaked 20-30 minute, decocts then 30 minutes, decocts after-filtration, removes slag, extracting solution continues to employ.

The case choice criteria:

Skin is scorching hot, the blocky edema welt of limitation that differs in size appears rapidly in flushing, pale red, affected part, little of the grain of rice, big to the palm size, common be fingernail to coin-size, a little more than surrounding skin, the most outstanding symptom is the violent pruritus in affected part, and grab and more itch, can cause expanded range and disease to increase the weight of, conscious affected part is scorching hot hard to bear, all belongs to this therapeutic domain.

Select 90 routine conformance with standard patients according to above-mentioned case choice criteria, male's 39 examples wherein, women's 51 examples, the oldest 76 years old minimum 10 years old, medical history is all more than 1 year, the longest 20 years, all by treated by the anti-resistance of doctor trained in Western medicine utilization amine, external hormones ointment, all respite appears, but outbreak repeatedly in a short time, office itches unbearably, cuts and grabs and more itch, and is painful unusual.

Be coated with instant effect person sx 50% after 30 minutes behind the pharmaceutical composition of treatment dermatosis chronic disease through external, embrocate the disappearance of itching repeatedly 3 times, erythema disappears, and absorbs slow person, 2-3 sx of the pharmaceutical composition of exterior coating treatment dermatosis chronic disease, itched in 2 days and end, erythema disappears, and welt disappears.

Have 1 example to interrupt because of getting in touch behind the affected part ulceration coating 1 time in 90 examples, residue 89 examples are treated effective percentage and are reached for 100%, through paying a return visit no one's recurrence in 3 years

Clinical case:

Case 1:

Huang Deshan: man 53 years old is because of eating anaphylactogen and the back shirtfront back of drinking is given prominence to the big welt of fingernail, burning and red skin color, play and itched unbearably, grab scabies and occurred transudate, can't fall asleep night, susceptible to lose temper due to restlessness, through outside be coated with the pharmaceutical composition 3 times of treatment dermatosis chronic disease of the present invention after, play is itched and is reduced by half, erythema disappears, skin transfers to normally after being coated with 4 days, cures, does not have recurrence so far through paying a return visit.

Case 2:

Zhang Fengshan: 49 years old, because of the wind-engaging arm upper process welt of perspiring behind the contact allergy source, be coated with respite behind the hormone ointment, cross the back play of 1 week and itch unbearably, agonizing, welt reduces half behind the pharmaceutical composition of exterior coating treatment dermatosis chronic disease 2 times, cures for 5 times.

Case 3:

Li Hong English 73 women allergies 12 years can't be cured, and recurrence delay is difficult, and after the pharmaceutical composition effect that the pleasant to the ear patient of serious irritated recurrence once will treat dermatosis chronic disease was informed, she used healing fully after 1 week, does not have recurrence so far.

Case 4

Li Yingfen, woman, 73, allergies 20 years, burst is irritated, on the face, scorching hot everywhere flushing on one's body, welt, erythema spreads all over whole body, and play is itched incessantly, misery is unusual, and the part goes out sepage after grabbing scabies on one's body, after being coated with the pharmaceutical composition of treatment dermatosis chronic disease of the present invention continuously, itch and end, erythema is moved back, and pays a return visit after 3 months and does not have recurrence.

The pharmaceutical composition that the present invention treats dermatosis chronic disease is suitable for disease: prurigo infantilis, prurigo gestationis, neurodermatitis, erythematous eruption, eczema, prurigo, urticaria (welt, rubella wheal) papular urticaria, prurigo nodularis, after the pleiomorphism erythra is grabbed transudate is arranged, all kinds fungal infection and cause violent pruritus person, the hormone dependent, hormone with after send out the author repeatedly, all can use.

The pharmaceutical composition of treatment dermatosis chronic disease is a pure Chinese medicinal preparation; do not contain any hormone, antiseptic, instant effect person coating took effect in 30 minutes; itched the same day and ended; it is antipruritic to absorb slow person 2 days, and instant effect does not recur, this medicine protection skin; also have antiallergic, anti-inflammation and sterilization, the detoxifcation erythema (welt, rubella wheal) of invigorating blood circulation, disappear to have and enhance metabolism and the normal repair ability of cell; make the skin speedy recovery to health, skin smooth after 1 week recovers normal.

Usage: the affected part warm water cleaning dries, and dips in magical antipruritic liquid with cotton swab and directly is coated with the affected part, and dip in liquid medicine is embrocated till the affected part heating repeatedly, and severe patient can be coated with 1 time in 2 hours, and the affected part must not get wet and clean behind the coating.

Points for attention: must not take orally, not be taken orally, go into the unavailable this product of ophthalmic and skin ulceration place, be placed on the place that children's does not get.

Claims (2)

1. a pharmaceutical composition for the treatment of dermatosis chronic disease is characterized in that being made up of the medicine of following weight part ratio: Caulis Vernoniae andersonii 2-4 part, Herba Sambuci Adnatae 1-2 part, Herba Sophorae alopecuroidis 3-5 part, Radix Sophorae Flavescentis 4-6 part, Rhizoma Polygoni Cuspidati 5-7 part, Cortex Dictamni 3-5 part, Semen Coicis 2-4 part, Semen Plantaginis 1-2 part, Semen Euryales 1-2 part.

2. a preparation of drug combination method for the treatment of dermatosis chronic disease is characterized in that comprising the steps: part with Caulis Vernoniae andersonii 2-4, Herba Sambuci Adnatae 1-2 part, Herba Sophorae alopecuroidis 3-5 part, Radix Sophorae Flavescentis 4-6 part, Rhizoma Polygoni Cuspidati 5-7 part, Cortex Dictamni 3-5 part, Semen Coicis 2-4 part, Semen Plantaginis 1-2 part, Semen Euryales 1-2 part was directly soaked 20-30 minute, decocted then 30 minutes, decoct after-filtration, remove slag, extracting solution continues to employ.