CN101708003B - Sterilizing composition containing active ester - Google Patents
Sterilizing composition containing active ester Download PDFInfo
- Publication number
- CN101708003B CN101708003B CN 200910261164 CN200910261164A CN101708003B CN 101708003 B CN101708003 B CN 101708003B CN 200910261164 CN200910261164 CN 200910261164 CN 200910261164 A CN200910261164 A CN 200910261164A CN 101708003 B CN101708003 B CN 101708003B
- Authority
- CN
- China
- Prior art keywords
- acibenzolar
- iprovalicarb
- propamocarb
- composition
- benzene metsulfovax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000005797 Iprovalicarb Substances 0.000 claims abstract description 44
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- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000003516 soil conditioner Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 238000009333 weeding Methods 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a sterilizing composition containing active ester, which comprises effective components such as active ester (A) and one (B) of iprovalicarb, benthiavalicarb and propamocarb, wherein the weight ratio of the A and B is 100:1-1:100, and the content of the active component in the composition is 10-80 in percentage by weight. The composition can be prepared in to suspending agents, wetting powder, water dispersible granules, and the like. The sterilizing composition can be applied to farmlands, orchards and the like and is used for controlling various plantdiseases of grains, vegetables, fruit trees, flowers, and the like, in particular downy mildew and epidemic diseases.
Description
Technical field
The present invention relates to a kind of bactericidal composition, especially contain the bactericidal composition of Acibenzolar and iprovalicarb or benzene metsulfovax or Propamocarb, composition has protection, preventive and therapeutic action, belongs to the disinfectant use in agriculture field.
Background technology
Downy mildew is a kind of most important disease on gourd, fruit and vegetable is produced.All can occur to each stage of results from seedling, it is heavier to be injured with strain.The blade of mainly causing harm is developed to upper leaf by base portion.Their early stage forms light yellow subcircular to the polygonal scab on the blade face, blade back produced the mould layer of white shape when there was dampness in the air, sometimes can spread to the blade face.The later stage scab is in flakes withered, is yellowish-brown, the withered and yellow death of whole siphonal lobes when serious.The easily morbidities such as field planting is overstocked, it is too early, excessive to water after the field planting, soil moisture large, impeded drainage.Spring is early summer or the easiest generation of continuous rainy weather in autumn not.Especially occur general with cucumber, sponge gourd, balsam pear, muskmelon in melon and be injured heavier.
Downy mildew is the very strong disease of a kind of popularity, in the vegetable-growing area of not planting disease-resistant variety, and light underproduction 30-40% then when disease is popular, serious reaches more than the 70-80%, so that ruin kind.
Epidemic disease mainly refers to by the fungus-caused class disease of Phytophthora (Phytophthora), mainly cause plant flowers, really, the quick necrosis of leaf section tissue and rotting.High humidity is to affect the principal element that disease occurs and propagates.Wherein melon epidemic disease and potato late blight are important diseases.
In the control of downy mildew and epidemic disease, mainly rely on metalaxyl, dimethomorph and some protectiveness medicaments.These medicaments are because long-term use has produced pesticide resistance in various degree, and control efficiency reduces.Simultaneously a large amount of uses of medicament have increased residue of pesticide, and the harm food security has increased the weight of environmental pollution.
Acibenzolar is diazosulfide carboxylic acid esters Plant activator.Acibenzolar English name acibenzolar chemical name benzo (1,2,3) thiadiazoles-7-carbothioic acid-S-methyl esters test code number CGA245704 is called for short BTH, molecular formula C
8H
6N
2OS
2
Acibenzolar obtains resistance by the defense response that activates crop self, thereby resists the diseases such as powdery mildew, downy mildew, rust.Suitable crop has paddy rice, wheat, vegetables, banana, tobacco etc.
Pesticide active ingredient applied in any combination with Acibenzolar and other structure type, there is the composition of synergistic effect not only can obviously improve actual preventive effect, reduce dosage and cost, also help to avoid the generation of germ resistance and delay drug-fast generation speed, thereby solve the problems such as resistance in the present agricultural chemicals single dose application process and cost.
Summary of the invention
The object of the present invention is to provide that a kind of new resistance risk is little, cost is low, good drug efficacy, long bactericidal composition of lasting period.
The inventor is by a large amount of indoor biometrics and field control effectiveness tests, after in unexpected discovery Acibenzolar and carbamate fungicide iprovalicarb, benzene metsulfovax, the Propamocarb any one is mixed in certain proportion, the diseases such as downy mildew, epidemic disease there is significant synergistic effect.
Described iprovalicarb, English name iprovalicarb, chemical name 2-methyl isophthalic acid-[(1-p-methylphenyl ethyl) carbamoyl]-(S)-propyl carbamic acid isopropyl ester, molecular formula C
18H
28N
2O
3
The controlling object of iprovalicarb is that downy mildew, epidemic disease are like downy mildew of garpe, potato late blight, tomato late blight, cucumber downy mildew, black shank etc.
Described benzene metsulfovax, English name benthiavalicarb, chemical name [(S)-1-[(R)-1-(6-fluoro benzothiazole-2-yl) ethylamino formoxyl]-the 2-methyl-propyl] carbamic acid isopropyl ester, molecular formula C
18H
24FN
3O
3S.
The benzene metsulfovax has very strong prevention, treatment, osmotically active, and good lasting effect and Nai Yu erosion are arranged.In the field trial, the benzene metsulfovax can be controlled the downy mildew of late blight, grape and other crops of potato and tomato effectively with lower dosage (per hectare 25-75 restrains active ingredient).
Described Propamocarb, English name Propamocarb, chemical name 3-(dimethylamino) propyl carbamic acid n-propyl, molecular formula C
9H
21CLN
2O
2
The mechanism of action of Propamocarb is to suppress the phosphoric acid of germ cell membrane component and synthesizing of fatty acid, suppresses mycelial growth and spreads and sporangial formation and spore germination.Desirable to control efficiency such as the downy mildew of gourd, fruit and vegetable, epidemic disease, damping off, late blight, cotton disease, white blisters.
The inventor is on the basis of above-mentioned discovery, through composition is carried out symphyogenetic quantitative analysis, formed technical scheme of the present invention, that is: a kind of bactericidal composition, the mass ratio of any one (B) in Acibenzolar in the composition (A) and iprovalicarb, benzene metsulfovax, the Propamocarb is 100: 1～1: 100, and A is 30: 1～1: 40 with B quality optimization ratio.Active component gross mass percentage composition is 10～80% in the composition.
The present composition can be prepared into known method any one formulation that is fit to agricultural use, and formulation has suspending agent, wetting powder, water dispersible granules etc. preferably.These preparations can be by general method preparation, for example, active substance is mixed with liquid flux and/or solid carrier, add simultaneously surfactant such as emulsifier, dispersant, stabilizing agent, wetting agent, can also add adhesive, defoamer, oxidant, dyestuff etc.
For suspending agent, one or more in spendable dispersant such as polycarboxylate, lignosulfonates such as lignin sulfonic acid sodium salt, the alkylnaphthalene sulfonate; Among emulsifier such as Nongru-700 # (common name alkyl phenol formaldehyde resin polyoxyethylene ether), nekal formaldehyde condensation products, agricultural newborn 2201#, this dish-60# (common name sorbitol anhydride monostearate), agricultural newborn 1601# (common name triphen ethyl-phenol polyoxyethylene polyoxypropylene block polymer), the TERSPERSE 4894 (2500) one or more; In wetting agent such as alkylphenol-polyethenoxy base ether formaldehyde condensation products phosphate, the withered powder of tea, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, spaonin powder, silkworm excrement, the soapberry powder one or more; In thickener such as xanthans, polyvinyl alcohol, bentonite, CMC, methylcellulose, the Magnesiumaluminumsilicate one or more; In preservative such as formaldehyde, benzoic acid, the Sodium Benzoate one or more; Defoamer such as organic silicon defoamer; In antifreezing agent such as ethylene glycol, propane diols, glycerine, urea, inorganic salts such as the sodium chloride one or more.
For water dispersible granules, one or more in spendable dispersant such as polycarboxylate, lignosulfonates, NNO4, the alkylnaphthalene sulfonate; In wetting agent such as polyoxyethylene nonylphenol ether, polyoxyethylene alcohol, alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; In disintegrant such as ammonium sulfate, urea, sucrose, the glucose one or more; In binding agent such as diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose one or more; In filler such as diatomite, calcium bicarbonate, kaolin, white carbon, talcum powder, the potter's clay one or more.
For wetting powder, in spendable dispersant such as polycarboxylate, lignosulfonates, the alkylnaphthalene sulfonate one or more; In wetting agent such as alkyl sulfate, alkylsulfonate, the naphthalene sulfonate one or more; In filler such as ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, the potter's clay one or more.
The present composition can be the finished product preparation form to be provided, and namely each material mixes in the composition; The composition of composition also can provide with the single dose preparation, directly mixes in bucket (tank) before using.Concentrate of the present invention usually and water be mixed to get the concentration of required active substance.
Composition of the present invention can be used for preventing and treating the important disease that is caused by sac fungi, oomycetes etc., is particularly suitable for preventing and treating downy mildew, epidemic disease.It is farmland, orchard etc. that composition of the present invention is used the place.
Composition of the present invention also can with other compound with weeding, desinsection or bactericidal property particularly protective fungicide mix use, also can mix use with nematocide, protective agent, growth regulator, nutrient for plants or soil conditioner.
The present invention also comprises a kind of method of on-the-spot killing fungus, before or after crop and/or fruit are susceptible, uses composition of the present invention to the place of crop and/or fruit and growth or storage.Can use by common method, such as cast, injection, spraying, dusting, distribution.Amount of application of the present invention is with weather condition or crop state variation.The duration of protective effect is usually relevant with the content of individualized compound in the composition, and is relevant with extraneous factor, weather for example, but by using suitable formulation can slow down climatic influences.
Composition of the present invention possesses following advantage: the one, and the composition synergistic effect is obvious, and drug effect significantly improves; The 2nd, the composition drug effect improves, and the field consumption descends, and has reduced production and use cost, reduces residue of pesticide and environmental pollution; The 3rd, composition is comprised of the active ingredient of different mechanism of action, and action site increases, and is conducive to overcome and delays the drug-fast generation of germ.The 4th, enlarged fungicidal spectrum, can prevent and treat downy mildew disease such as powdery mildew in addition.
Embodiment
Different pesticide active ingredients shows three kinds of type of action: summation action, synergistic effect and antagonism after mixing usually.But be specially which kind of effect, unpredictable, only have by lot of experiments and just can know.Compound synergic is well filled a prescription, owing to obviously improved actual control efficiency, reduced the usage amount of agricultural chemicals, thereby delayed widely the drug-fast generation speed of germ, and be the important means of scientific prevention and cure disease.
The inventor has carried out a large amount of indoor bioassay test and field control effectiveness test, find that any one combination in Acibenzolar and iprovalicarb, benzene metsulfovax, the Propamocarb has significant synergistic function to Pseudoperonospora cubensis etc. afterwards, and be not only the simple addition (seeing biologicall test example 1 for details) of two kinds of medicaments.
Biologicall test embodiment 1: the composite Toxicity Determination to bacterium of downy mildew of cucumber of any one in Acibenzolar and iprovalicarb, benzene metsulfovax, the Propamocarb
Subjects: bacterium of downy mildew of cucumber (Pseudoperonospora cubensis)
Pot-culture method is adopted in this test.Choose two consistent leaf period cucumber seedlings of growing way, each processing selects 5 basins for examination melon seedling, numbers for subsequent use.Under 50PSI pressure, spray every basin 5mL with the Potter spray tower.Each medicament arranges 5 concentration gradients, take spray the equivalent clear water as blank.Spray inoculation bacterium of downy mildew of cucumber sporangia suspension behind the chemicals treatment 24h, the layoutprocedure of sporangia suspension is as follows: get the cucumber leaves with Pseudoperonospora cubensis that picks up from the field, dip the sporangium that distilled water about 10 ℃ washes the back side with writing brush, being made into concentration is 3 * 10
5The sporangia suspension of individual/mL.After the inoculation cucumber seedling placed climatic cabinate (relative moisture 100%, temperature 15-20 ℃) cultivate, keep 15-24 ℃ of temperature, relative moisture 90% left and right sides moisturizing to bring out behind the 24h, 10d " Invest, Then Investigate " record incidence calculates disease index and control efficiency.
The cucumber downy mildew grade scale:
0 grade: blade is without scab;
1 grade: lesion area accounts for below 5% of whole blade area;
3 grades: lesion area accounts for the 6-10% of whole blade area;
5 grades: lesion area accounts for the 11-25% of whole blade area;
7 grades: lesion area accounts for the 26-50% of whole blade area;
9 grades: lesion area accounts for more than 50% of whole blade area.
The expection effectiveness of mixture of active principles (be theoretical control efficiency, %) use Colby formula is determined and is compared with the effectiveness of observing:
Colby formula: E=X+Y-X*Y/100
E: the active components A working concentration is a in composition, and the compositions contemplated when active component B working concentration is b is renderd a service,
X: the effectiveness when the active components A using dosage is a,
Y: the effectiveness when active component B using dosage is b.
The explanation mixture has synergistic effect when the actual control efficiency of observing surpasses the expection preventive effect.
Toxicity test result referring to table 1 to table 4.
The independent reactive compound of table 1 is to the pot experiment measurement result of cucumber downy mildew
The composite pot experiment measurement result to cucumber downy mildew of table 2 Acibenzolar and iprovalicarb
| Embodiment | Activity component concentration (ppm: ppm) in the mixture | Practical effect (%) | (%) renderd a service in expection |
| 1 | Acibenzolar 100: iprovalicarb 1 | 84.2 | 79.7 |
| 2 | Acibenzolar 70: iprovalicarb 1 | 67.8 | 60.6 |
| 3 | Acibenzolar 30: iprovalicarb 1 | 49.4 | 41.9 |
| 4 | Acibenzolar 10: iprovalicarb 1 | 31.5 | 24.9 |
| 5 | Acibenzolar 10: iprovalicarb 10 | 54.3 | 46.0 |
| 6 | Acibenzolar 1: iprovalicarb 10 | 43.2 | 38.5 |
| 7 | Acibenzolar 1: iprovalicarb 40 | 69.7 | 63.8 |
| 8 | Acibenzolar 0.5: iprovalicarb 40 | 65.2 | 61.8 |
| 9 | Acibenzolar 0.5: iprovalicarb 50 | 73.8 | 69.4 |
Result of the test shows that the composite control cucumber downy mildew of Acibenzolar and iprovalicarb has synergistic effect.
The composite pot experiment measurement result to cucumber downy mildew of table 3 Acibenzolar and benzene metsulfovax
| Embodiment | Activity component concentration (ppm: ppm) in the mixture | Practical effect (%) | (%) renderd a service in expection |
| 1 | Acibenzolar 100: benzene metsulfovax 1 | 85.3 | 82.1 |
| 2 | Acibenzolar 70: benzene metsulfovax 1 | 69.5 | 65.2 |
| 3 | Acibenzolar 30: benzene metsulfovax 1 | 52.1 | 48.7 |
| 4 | Acibenzolar 10: benzene metsulfovax 1 | 39.6 | 33.7 |
| 5 | Acibenzolar 10: benzene metsulfovax 10 | 60.4 | 57.5 |
| 6 | Acibenzolar 1: benzene metsulfovax 10 | 57.5 | 51.6 |
| 7 | Acibenzolar 1: benzene metsulfovax 40 | 85.7 | 80.6 |
| 8 | Acibenzolar 0.5: benzene metsulfovax 40 | 82.8 | 79.5 |
| 9 | Acibenzolar 0.5: benzene metsulfovax 50 | 91.9 | 87.1 |
Result of the test shows that the composite control cucumber downy mildew of Acibenzolar and benzene metsulfovax has synergistic effect.
The composite pot experiment measurement result to cucumber downy mildew of table 4 Acibenzolar and Propamocarb
| Embodiment | Activity component concentration (ppm: ppm) in the mixture | Practical effect (%) | (%) renderd a service in expection |
| 1 | Acibenzolar 100: Propamocarb 1 | 81.3 | 78.2 |
| 2 | Acibenzolar 70: Propamocarb 1 | 62.5 | 57.6 |
| 3 | Acibenzolar 30: Propamocarb 1 | 48.9 | 37.5 |
| 4 | Acibenzolar 10: Propamocarb 1 | 28.6 | 19.2 |
| 5 | Acibenzolar 10: Propamocarb 10 | 36.9 | 29.8 |
| 6 | Acibenzolar 1: Propamocarb 10 | 28.3 | 20.1 |
| 7 | Acibenzolar 1: Propamocarb 40 | 52.7 | 45.1 |
| 8 | Acibenzolar 0.5: Propamocarb 40 | 49.5 | 42.1 |
| 9 | Acibenzolar 0.5: Propamocarb 50 | 56.3 | 47.6 |
Result of the test shows that the composite control cucumber downy mildew of Acibenzolar and Propamocarb has synergistic effect.
Below further specify the present invention with specific embodiment, but the present invention is limited to absolutely not these examples.The following stated only is preferably embodiment of the present invention, only in order to explain the present invention, can not therefore be interpreted as the restriction to claim of the present invention.Should be pointed out that all any modifications of making within the spirit and principles in the present invention, be equal to replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Percentage composition is mass percent in all preparation proportionings.
The suspending agent example
Press formula rate, the ratio of each component such as active component, dispersant, wetting agent, thickener, antifreeze and water in prescription mixed, after grinding or high speed shear, make suspending agent.
Embodiment 1:20.2% Acibenzolar iprovalicarb suspending agent
Acibenzolar 20%, iprovalicarb 0.2%, methyl naphthalene sulfonate formaldehyde condensate (dispersant) 10%, lauryl sodium sulfate (wetting agent) 3%, xanthans (thickener) 2%, bentonite (thickener) 1%, glycerine (antifreeze) 5%, water complements to 100%.
Embodiment 2:30.3% Acibenzolar iprovalicarb suspending agent
Acibenzolar 0.3%, iprovalicarb 30%, polycarboxylate (dispersant) 10%, the withered powder of tea (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, bentonite (thickener) 1%, ethylene glycol (antifreeze) 5%, water complements to 100%.
Embodiment 3:30.3% Acibenzolar benzene metsulfovax suspending agent
Acibenzolar 30%, benzene metsulfovax 0.3%, lignin sulfonic acid sodium salt (dispersant) 10%, lauryl sodium sulfate (wetting agent) 3%, xanthans (thickener) 2%, polyvinyl alcohol (thickener) 1%, propane diols, (antifreeze) 5%, water complements to 100%.
Embodiment 4:10.1% Acibenzolar benzene metsulfovax suspending agent
Acibenzolar 0.1%, benzene metsulfovax 10%, alkylnaphthalene sulfonate (dispersant) 10%, the withered powder of tea (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, bentonite (thickener) 1%, urea (antifreeze) 5%, water complements to 100%.
Embodiment 5:20.2% Acibenzolar Propamocarb suspending agent
Acibenzolar 20%, Propamocarb 0.2%, methyl naphthalene sulfonate formaldehyde condensate (dispersant) 10%, alkylsulfonate (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, xanthans (thickener) 1%, glycerine (antifreeze) 5%, water complements to 100%.
Embodiment 6:30.3% Acibenzolar Propamocarb suspending agent
Acibenzolar 0.3%, Propamocarb 30%, polycarboxylate (dispersant) 10%, alkyl sulfate (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, xanthans (thickener) 1%, ethylene glycol (antifreeze) 5%, water complements to 100%.
Embodiment 7:10% Acibenzolar iprovalicarb suspending agent
Acibenzolar 2%, iprovalicarb 8%, polycarboxylate (dispersant) 10%, lauryl sodium sulfate (wetting agent) 3%, xanthans (thickener) 2%, bentonite (thickener) 1%, urea (antifreeze) 5%, water complements to 100%.
Embodiment 8:10% Acibenzolar benzene metsulfovax suspending agent
Acibenzolar 1%, benzene metsulfovax 9%, methyl naphthalene sulfonate formaldehyde condensate (dispersant) 10%, lauryl sodium sulfate (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, xanthans (thickener) 1%, sodium chloride (antifreeze) 5%, water complements to 100%.
Embodiment 9:10% Acibenzolar Propamocarb suspending agent
Acibenzolar 9%, Propamocarb 1%, polycarboxylate (dispersant) 10%, spaonin powder (wetting agent) 3%, xanthans (thickener) 2%, bentonite (thickener) 1%, urea (antifreeze) 5%, water complements to 100%.
Embodiment 10:31% Acibenzolar iprovalicarb suspending agent
Acibenzolar 30%, iprovalicarb 1%, polycarboxylate (dispersant) 10%, silkworm excrement (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, bentonite (thickener) 1%, propane diols (antifreeze) 5%, water complements to 100%.
Embodiment 11:20.5% Acibenzolar benzene metsulfovax suspending agent
Acibenzolar 0.5%, benzene metsulfovax 20%, polycarboxylate (dispersant) 10%, soapberry powder (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, bentonite (thickener) 1%, glycerine (antifreeze) 5%, water complements to 100%.
Embodiment 12:31% Acibenzolar Propamocarb suspending agent
Acibenzolar 30%, Propamocarb 1%, polycarboxylate (dispersant) 10%, the withered powder of tea (wetting agent) 3%, polyvinyl alcohol (thickener) 2%, xanthans (thickener) 1%, urea (antifreeze) 5%, water complements to 100%.
The wetting powder example
Pesticide activity component, auxiliary agent, filler mixed behind air-flow crushing to mix in proportion again make wetting powder.Capital equipment: mixer, airslide disintegrating mill.
Embodiment 13:80% Acibenzolar iprovalicarb wetting powder
Acibenzolar 60%, iprovalicarb 20%, lauryl sodium sulfate (wetting agent) 2%, sodium lignin sulfonate (dispersant) 3%, White Carbon black 10% (filler), kaolin complements to 100%.
Embodiment 14:80% Acibenzolar benzene metsulfovax wetting powder
Acibenzolar 30%, benzene metsulfovax 50%, lauryl sodium sulfate (wetting agent) 2%, sodium lignin sulfonate (dispersant) 3%, diatomite 10% (filler), potter's clay complements to 100%.
Embodiment 15:80% Acibenzolar Propamocarb wetting powder
Acibenzolar 40%, Propamocarb 40%, lauryl sodium sulfate (wetting agent) 2%, sodium lignin sulfonate (dispersant) 3%, talcum powder 10% (filler), attapulgite complements to 100%.
Embodiment 16:20.5% Acibenzolar iprovalicarb wetting powder
Acibenzolar 0.5%, iprovalicarb 20%, alkyl sulfate (wetting agent) 3%, polycarboxylate (dispersant) 3%, White Carbon black (filler) 11%, bentonite complements to 100%.
Embodiment 17:31% Acibenzolar benzene metsulfovax wetting powder
Acibenzolar 30%, benzene metsulfovax 1%, alkyl sulfate (wetting agent) 3%, polycarboxylate (dispersant) 3%, kaolin (filler) 11%, attapulgite complements to 100%.
Embodiment 18:20.5% Acibenzolar Propamocarb wetting powder
Acibenzolar 0.5%, Propamocarb 20%, alkyl sulfate (wetting agent) 3%, polycarboxylate (dispersant) 3%, talcum powder (filler) 11%, bentonite complements to 100%.
Embodiment 19:70% Acibenzolar iprovalicarb wetting powder
Acibenzolar 40%, iprovalicarb 30%, alkylsulfonate (wetting agent) 3%, sodium lignin sulfonate (dispersant) 3%, White Carbon black (filler) 11%, potter's clay complements to 100%.
The water dispersible granules example
Press formula rate, former medicine and powder carrier, moistening spreader-sticker and binding agent etc. are carried out co-grinding, after adding again water and mediating, add in the comminutor that the certain specification screen cloth is housed and carry out granulation.And then drying, screening (by the screen cloth scope) namely get granular product.
Embodiment 20:30% Acibenzolar iprovalicarb water dispersible granules
Acibenzolar 15%, iprovalicarb 15%, polycarboxylate (dispersant) 5%, sodium lignin sulfonate (dispersant) 7%, lauryl sodium sulfate (wetting agent) 2%, ammonium sulfate (disintegrant) 5%, precipitated calcium carbonate complements to 100%.
Embodiment 21:40% Acibenzolar benzene metsulfovax water dispersible granules
Acibenzolar 5%, benzene metsulfovax 35%, Negel (dispersant) 5%, sodium lignin sulfonate (dispersant) 7%, lauryl sodium sulfate (wetting agent) 2%, urea (disintegrant) 5%, precipitated calcium carbonate complements to 100%.
Embodiment 22:35% Acibenzolar Propamocarb water dispersible granules
Acibenzolar 20%, Propamocarb 15%, Negel (dispersant) 5%, sodium lignin sulfonate (dispersant) 7%, lauryl sodium sulfate (wetting agent) 2%, glucose (disintegrant) 5%, precipitated calcium carbonate complements to 100%.
Embodiment 23:20% Acibenzolar benzene metsulfovax water dispersible granules
Acibenzolar 18%, benzene metsulfovax 2%, polycarboxylate (dispersant) 5%, sodium lignin sulfonate (dispersant) 7%, lauryl sodium sulfate (wetting agent) 2%, ammonium sulfate (disintegrant) 5%, precipitated calcium carbonate complements to 100%.
Field application examples 1: the composite field control effectiveness test to downy mildew of garpe of Acibenzolar and iprovalicarb
Choose the throughout the year heavier plot of morbidity of downy mildew of garpe.Test medicine and consumption see Table 5, and 20 square metres of each residential quarter areas are repeated in 4 residential quarters of every processing.Carry out the dispenser first time at the disease initial stage of origination, the complete stool even spraying till being sprayed onto blade and dripping, is treated to blank with clear water.Execute for the second time medicine after 7 days.The incidence of 7 days investigation downys mildew of garpe behind the medicine before first time medicine and for the second time.5 samplings are adopted in every residential quarter, every some investigation 2 strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area comes the classification record.Calculate and respectively process disease index and control efficiency.
Grade scale:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for more than 50% of whole leaf area.
The drug effect computational methods:
As can be seen from Table 5: Acibenzolar, each single dose of iprovalicarb to the preventive effect of downy mildew of garpe be respectively 73.81% and 76.38%,, and embodiment of the invention bactericidal composition all is significantly increased on preventive effect, minimum preventive effect is 85.40%, has been up to 90.14%.The result of field trial fully shows, Acibenzolar and iprovalicarb are composite to have significant synergistic function afterwards to downy mildew of garpe, and in the situation that the mu effective ingredient consumption reduces, control efficiency significantly improves.Therefore, the present composition has the beneficial effect that reduces cost, delaying drug resistance, minimizing spraying times and residue of pesticide.
The composite field test results to downy mildew of garpe of table 5 Acibenzolar and iprovalicarb
| Reagent agent | Dosage (ga.i./ha) | Disease index before the medicine | Behind the 2nd medicine 7 | Preventive effect (%) |
| It disease index | ||||
| 50% Acibenzolar wetting powder | 50 | 2.7 | 6.5 | 73.81 |
| 30% iprovalicarb suspending agent | 150 | 3.5 | 7.6 | 76.38 |
| Example of formulations 1 (20.2% Acibenzolar iprovalicarb suspending agent) | 45 | 2.9 | 3.3 | 87.62 |
| Example of formulations 2 (30.3% Acibenzolar iprovalicarb suspending agent) | 60 | 3.8 | 5.1 | 85.40 |
| Example of formulations 7 (10% Acibenzolar iprovalicarb suspending agent) | 48 | 3.4 | 4.3 | 86.24 |
| Example of formulations 10 (31% Acibenzolar iprovalicarb suspending agent) | 42 | 3.2 | 2.9 | 90.14 |
| Example of formulations 13 (80% Acibenzolar iprovalicarb wetting powder) | 45 | 2.5 | 3.1 | 86.51 |
| Example of formulations 16 (20.5% Acibenzolar iprovalicarb wetting powder) | 48 | 3.3 | 3.9 | 87.15 |
| Example of formulations 20 (30% Acibenzolar iprovalicarb water dispersible granules) | 45 | 2.7 | 3.4 | 86.30 |
| CK | - | 3.1 | 28.5 | - |
Field application examples 2: the composite field control effectiveness test to tomato late blight of Acibenzolar and benzene metsulfovax
Choose the throughout the year heavier plot of morbidity of tomato late blight.Test medicine and consumption see Table 6, and 20 square metres of each residential quarter areas are repeated in 4 residential quarters of every processing.Carry out the dispenser first time at the disease initial stage of origination, the complete stool even spraying till being sprayed onto blade and dripping, is treated to blank with clear water.Execute for the second time medicine after 7 days.The incidence of 7 days investigation tomato late blights behind the medicine before first time medicine and for the second time.5 samplings are adopted in every residential quarter, every some investigation 3 strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area comes the classification record.Calculate and respectively process disease index and control efficiency.
Grade scale:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for more than 50% of whole leaf area.
The drug effect computational methods:
As can be seen from Table 6: Acibenzolar, each single dose of benzene metsulfovax to the preventive effect of tomato late blight be respectively 74.28% and 78.23%,, and embodiment of the invention bactericidal composition all is significantly increased on preventive effect, minimum preventive effect is 85.29%, has been up to 91.04%.The result of field trial fully shows, Acibenzolar and benzene metsulfovax are composite to have significant synergistic function afterwards to tomato late blight, and in the situation that the mu effective ingredient consumption reduces, control efficiency significantly improves.Therefore, the present composition has the beneficial effect that reduces cost, delaying drug resistance, minimizing spraying times and residue of pesticide.
The composite field test results to tomato late blight of table 6 Acibenzolar and benzene metsulfovax
| Reagent agent | Dosage (ga.i./ha) | Disease index before the medicine | 7 days disease indexs behind the 2nd medicine | Preventive effect (%) |
| 50% Acibenzolar wetting powder | 50 | 3.6 | 10.7 | 74.28 |
| 25% benzene metsulfovax suspending agent | 75 | 3.1 | 7.8 | 78.23 |
| Example of formulations 3 (30.3% Acibenzolar benzene metsulfovax suspending agent) | 45 | 2.9 | 4.3 | 87.17 |
| Example of formulations 4 (10.1% Acibenzolar benzene metsulfovax suspending agent) | 48 | 3.2 | 5.1 | 86.21 |
| Example of formulations 8 (10% Acibenzolar benzene metsulfovax suspending agent) | 46 | 2.5 | 3.9 | 86.50 |
| Example of formulations 11 (20.5% Acibenzolar benzene metsulfovax suspending agent) | 48 | 3.0 | 5.1 | 85.29 |
| Example of formulations 14 (80% Acibenzolar benzene metsulfovax wetting powder) | 45 | 3.4 | 4.9 | 87.53 |
| Example of formulations 17 (31% Acibenzolar benzene metsulfovax wetting powder) | 42 | 2.8 | 2.9 | 91.04 |
| Example of formulations 21 (40% Acibenzolar benzene metsulfovax water dispersible granules) | 45 | 3.9 | 5.3 | 88.24 |
| CK | - | 2.7 | 31.2 | - |
Field application examples 3: the composite field control effectiveness test to cucumber downy mildew of Acibenzolar and Propamocarb
Choose the throughout the year heavier plot of morbidity of cucumber downy mildew.Test medicine and consumption see Table 7, and 20 square metres of each residential quarter areas are repeated in 4 residential quarters of every processing.Carry out the dispenser first time at the disease initial stage of origination, the complete stool even spraying till being sprayed onto blade and dripping, is treated to blank with clear water.Execute for the second time medicine after 7 days.The incidence of 7 days investigation cucumber downy mildews behind the medicine before first time medicine and for the second time.5 samplings are adopted in every residential quarter, every some investigation 2 strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area comes the classification record.Calculate and respectively process disease index and control efficiency.
Grade scale:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for more than 50% of whole leaf area.
The drug effect computational methods:
As can be seen from Table 7: Acibenzolar, each single dose of Propamocarb to the preventive effect of cucumber downy mildew be respectively 73.60% and 76.26%,, and embodiment of the invention bactericidal composition all is significantly increased on preventive effect, minimum preventive effect is 85.05%, has been up to 89.02%.The result of field trial fully shows, Acibenzolar and Propamocarb are composite to have significant synergistic function afterwards to cucumber downy mildew, and in the situation that the mu effective ingredient consumption reduces, control efficiency significantly improves.Therefore, the present composition has the beneficial effect that reduces cost, delaying drug resistance, minimizing spraying times and residue of pesticide.
The composite field test results to cucumber downy mildew of table 7 Acibenzolar and Propamocarb
| Reagent agent | Dosage (ga.i./ha) | Disease index before the medicine | 7 days disease indexs behind the 2nd medicine | Preventive effect (%) |
| 50% Acibenzolar wetting powder | 50 | 2.1 | 8.5 | 73.60 |
| 72.2% Propamocarb aqua | 650 | 2.5 | 9.1 | 76.26 |
| Example of formulations 5 (20.2% Acibenzolar Propamocarb suspending agent) | 45 | 1.7 | 3.1 | 88.11 |
| Example of formulations 6 (30.3% Acibenzolar Propamocarb suspending agent) | 200 | 2.4 | 5.5 | 85.05 |
| Example of formulations 9 (10% Acibenzolar Propamocarb suspending agent) | 48 | 1.5 | 3.1 | 86.52 |
| Example of formulations 12 (31% Acibenzolar Propamocarb suspending agent) | 42 | 1.9 | 3.2 | 89.02 |
| Example of formulations 15 (80% Acibenzolar Propamocarb wetting powder) | 48 | 2.4 | 4.7 | 87.23 |
| Example of formulations 18 (20.5% Acibenzolar Propamocarb wetting powder) | 180 | 2.2 | 4.0 | 88.14 |
| Example of formulations 22 (35% Acibenzolar Propamocarb water dispersible granules) | 45 | 1.6 | 3.3 | 86.55 |
| CK | - | 1.8 | 27.6 | - |
Claims (5)
1. bactericidal composition is characterized in that: active ingredient be Acibenzolar (A) with iprovalicarb, benzene metsulfovax, Propamocarb in a kind of (B), preferred 100: 1～1: 100 of the mass ratio of A and B.
2. bactericidal composition according to claim 1 is characterized in that: preferred 30: 1～1: 40 of the mass ratio of effective constituents A and B.
3. each described bactericidal composition according to claim 1-2, it is characterized in that: active component quality percentage composition is 10～80% in the composition.
4. bactericidal composition according to claim 1, it is characterized in that: said composition can be mixed with suspending agent, wetting powder, water dispersible granules.
5. bactericidal composition claimed in claim 1 is used for the disease on control cereal, vegetables, fruit tree, the flowers.
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| CN1455641A (en) * | 2000-09-12 | 2003-11-12 | 辛根塔参与股份公司 | Fungicidal compositions |
| CN101184391A (en) * | 2005-04-06 | 2008-05-21 | 拜尔农作物科学股份公司 | Synergistic fungicidal active substance combinations |
| CN101250167A (en) * | 2008-03-28 | 2008-08-27 | 南开大学 | Heterocyclic compounds containing thiadiazole as well as synthesis and uses thereof |
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| CN1455641A (en) * | 2000-09-12 | 2003-11-12 | 辛根塔参与股份公司 | Fungicidal compositions |
| CN101184391A (en) * | 2005-04-06 | 2008-05-21 | 拜尔农作物科学股份公司 | Synergistic fungicidal active substance combinations |
| CN101250167A (en) * | 2008-03-28 | 2008-08-27 | 南开大学 | Heterocyclic compounds containing thiadiazole as well as synthesis and uses thereof |
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