CN101703654B - Medicament patch for treating rheumatoid hyperostosis and preparation method thereof - Google Patents

Medicament patch for treating rheumatoid hyperostosis and preparation method thereof Download PDF

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Publication number
CN101703654B
CN101703654B CN2009102272423A CN200910227242A CN101703654B CN 101703654 B CN101703654 B CN 101703654B CN 2009102272423 A CN2009102272423 A CN 2009102272423A CN 200910227242 A CN200910227242 A CN 200910227242A CN 101703654 B CN101703654 B CN 101703654B
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parts
radix aconiti
preparation
stir
plaster
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CN101703654A (en
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张国平
张亚超
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Abstract

The invention provides a medicament patch for treating rheumatoid hyperostosis and a preparation method thereof. The medicament patch uses the following medicaments for removing rheumatism, driving pathogenic cold, warming channels, freeing blood vessels, invigorating the liver and the kidney, strengthening sinew and bone, diminishing inflammation and easing pain: 50 to 70 parts of raw strychnos, 60 to 85 parts of unprocessed radix aconiti, 50 to 70 parts of unprocessed radix aconiti kusnezoffii, 20 to 30 parts of scorpion, 20 to 30 parts of cassia bark, 20 to 40 parts of grub, 20 to 40 parts of dragon's blood, 40 to 50 parts of unprocessed frankincense, 40 to 50 parts of unprocessed myrrh, 20 to 40 parts of stir-baked squama manitis and 40 to 50 parts of manchurian wildginger. The medicaments are combined in use to jointly play a role in warming channels, removing stasis, driving wind, dispelling cold, feeing vessels, dispelling damp, removing inflammation and relieving pain. The medicament patch has a substrate combining the advantages of traditional plasters and various plasters in recent years; the medicament patch needs no roasting in use; the viscosity of the medicament patch is constant with the temperature of human body and is lasting; and the medicament patch still has good effect after being repeatedly torn and pasted for over 20 days. The medicament patch has the characteristics of good treatment effect, rapid effectiveness, convenient use and safe and nontoxic compatibility.

Description

Be used for the treatment of plaster of rheumatic hyperosteogeny and preparation method thereof
Technical field:
The present invention relates to a kind of Chinese medicine patch for the treatment of hyperosteogeny, particularly a kind of plaster that is used for the treatment of rheumatic hyperosteogeny and preparation method thereof is directly to be affixed on diseased region or the acupuncture point gets final product specifically.
Background technology:
The normal protracted course of disease of rheumatic arthritis shows effect repeatedly, takes other medicines and is controlling symptoms, not only can not effect a radical cure, also can liver injury, spleen and stomach function, cause a lot of complication, the patient suffering be can't bear, not only disability causes very big burden to family again.Use other plaster often easily to flow dirty linen, injure skin, general patient is reluctant to paste for a long time usefulness to cause disease can not adhere to treatment for a long time.Existing plaster mainly is with frying method processing in manufacturing process, causes drug effect to be lost, easy breaking out of fire and contaminated environment, and the subsides time spent needs baking, and easily stream causes the efficacy of a drug easily destroyed, causes shortcomings such as drug effect weak point.
Summary of the invention:
The objective of the invention is at above problem, and develop a kind of plaster that is used for the treatment of rheumatic hyperosteogeny and preparation method thereof, medication of the present invention is the medicine composition except that rheumatism, the heresy of dispeling cold, warming the meridian network, promoting blood circulation, invigorating the liver and kidney, strengthening bone and muscle, anti-inflammatory analgesic, existing effect of getting instant result has the merit of eradicating consolidation again; The substrate of this plaster is to choose the traditional plaster and the advantage of multiple plaster in recent years, and this plaster need not baking when using, and its viscosity is constant with the body temperature of human body, and viscosity is lasting, can take off repeatedly paste 20 surplus the sky still have good effect.Its substrate is stable, and plaster can not be out of shape under the room temperature, not pollution clothes, sheet etc.Not only the booming income crowd uses, and now general crowd all can bear.Because of drug loading is big, drug effect is rapidly lasting; Non-stimulated to skin, anaphylaxis.Have do not flow, advantage such as dirty linen not, patient can use in prolonged and repeated replacing, easily makes diseased region obtain long-term treatment, causes to reach complete at last.
Technical scheme of the present invention is achieved in that
A kind of plaster that is used for the treatment of rheumatic hyperosteogeny, it is that preparation of raw material by the following weight component forms: give birth to 50~70 parts of Semen Strychnis, 60~85 parts of Radix Aconiti, 50~70 parts of Radix Aconiti Kusnezoffii, 20~30 parts of Scorpios, 20~30 parts of Cortex Cinnamomis, 20~40 parts of Holotrichia diomphalia Batess, 20~40 parts of Sanguis Draxonis, 40~50 parts of Olibanum, 40~50 parts of Myrrha, 20~40 parts of stir-baked SQUAMA MANITISs, 40~50 parts of Herba Asaris.
Technical scheme of the present invention can be achieved in that
Give birth to 60 parts of Semen Strychnis, 75 parts of Radix Aconiti, 60 parts of Radix Aconiti Kusnezoffii, 30 parts of Scorpios, 30 parts of Cortex Cinnamomis, 30 parts of Holotrichia diomphalia Batess, 30 parts of Sanguis Draxonis, 45 parts of Olibanum, 45 parts of Myrrha, 30 parts of stir-baked SQUAMA MANITISs, 45 parts of Herba Asaris.
Technical scheme of the present invention can also be achieved in that
A kind of preparation method that is used for the treatment of the rheumatic hyperosteogeny plaster, it is that preparation of raw material by the following weight component forms: give birth to 50~70 parts of Semen Strychnis, 60~85 parts of Radix Aconiti, 50~70 parts of Radix Aconiti Kusnezoffii, 20~30 parts of Scorpios, 20~30 parts of Cortex Cinnamomis, 20~40 parts of Holotrichia diomphalia Batess, 20~40 parts of Sanguis Draxonis, 40~50 parts of Olibanum, 40~50 parts of Myrrha, 20~40 parts of stir-baked SQUAMA MANITISs, 40~50 parts of Herba Asaris;
Its preparation method may further comprise the steps:
The first step, by formulation weight with Sanguis Draxonis, Olibanum, do not have crude drug singly to grind 80 order fine powders respectively, be made as A material;
Second step, will give birth to Semen Strychni, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Cortex Cinnamomi, Holotrichia diomphalia Bates, stir-baked SQUAMA MANITIS, Herba Asari by formulation weight and be crushed to 80 order fine powders, be made as the B material;
The 3rd step, 100 parts of resins and 45 Colophonium parts are placed on vessel in heating, after waiting to dissolve into liquid, the B material are added stir earlier, and then the A material is added, and stir, be made as the C material;
The 4th goes on foot, the C that makes is expected, spread out and spare on the calico of 13 * 13cm, the thickness of C material is 3mm, and its area covers the strippable paper of 13 * 13cm then apart from calico edge 1cm on the C material, push with glass plate, is the plaster that is used for the treatment of rheumatic hyperosteogeny.
Technical scheme of the present invention can also be achieved in that described resin of the 3rd step is to adopt the PM-2C resin, is medical resin.
Therapeutic Method of the present invention is: at first affected part (or acupuncture point) cleaned up, again plaster is attached to the affected part, subsides can be pasted with 15~20 days, and the general state of an illness 1~2 is pasted, and the heavier person 3~5 of the state of an illness pastes and cures.
Pharmacology of the present invention is according to being:
Semen Strychni: nature and flavor: hardship, cold, poisonous.Return liver, spleen channel.Diffusing heat in blood, detumescence, pain relieving, activating collaterals and eliminating stagnation has excitation to the central nervous system.
Radix Aconiti: nature and flavor: hot, bitter, temperature; Very toxic.Be included into spleen, the gate of vitality's two warps.Effect: dispelling cold and dampness, the ailment said due to cold or exposure of loosing, warming the meridian, pain relieving.Be used for anemofrigid-damp arthralgia, trusted subordinate's cold type of pain, traumatic injury pain.
Radix Aconiti Kusnezoffii: nature and flavor: hot, hot, poisonous.Return liver, spleen, lung meridian.Effect: search wind prevailing over dampness, dispersing cold for relieving pain is controlled anemofrigid-damp arthralgia.
Scorpio: nature and flavor: salty, hot, flat, poisonous.Go into Liver Channel.Dispel the wind relieving convulsion, collateral dredging, detoxifcation.Control convulsion with spasms, apoplexy, hemiplegia.
Cortex Cinnamomi: nature and flavor: hot, sweet, heat.Go into kidney, spleen, urinary bladder channel.The complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
Holotrichia diomphalia Bates: nature and flavor: salty in the mouth, tepor.Go into liver channel of foot-Jueyin.Control and lose stasis of blood pain, gout.
Sanguis Draxonis: nature and flavor: sweet, salty, flat.GUIXIN, Liver Channel.Effect: be used for traumatic injury, swelling and pain due to blood stasis and Olibanum, Myrrha compatibility have the eliminating stasis to stop pain effect.
Olibanum; Nature and flavor: hot, bitter, temperature.Go into the heart, liver, spleen channel.Regulating qi and activating blood, analgesic therapy chases after poison, detumescence and promoting granulation.
Myrrha: nature and flavor: hardship, flat.Go into the heart, liver, spleen, kidney channel.Diffusing blood and dissolving stasis, subduing swelling and relieving pain.Be used to fall damage, muscles and bones, all pains of trusted subordinate.
Stir-baked SQUAMA MANITIS: nature and flavor: salty, cold.Go into liver, stomach warp.Function: the routed carbuncle of detumescence, it is active to search wind.It is swollen to be used for the carbuncle skin ulcer, diseases such as anemofrigid-damp arthralgia.Squama Manis is good at walking to scurry, and property specially row is loose, can collateral dredging and reach disease institute.
Herba Asari: nature and flavor; Suffering, temperature.Go into lung, kidney channel.Dispel the wind, cold expelling, pain relieving, row water is had one's ideas straightened out.
The foundation of the present invention's prescription is: Semen Strychni, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Cortex Cinnamomi, Holotrichia diomphalia Bates, Sanguis Draxonis, stir-baked SQUAMA MANITIS, Olibanum before the living horse, above Chinese medicine always are the rheumatismal principal agents of treatment.Living Semen Strychni, Radix Aconiti, Radix Aconiti Kusnezoffii, dehumidifying cold expelling drug effect fiercely are monarch; Cortex Cinnamomi, Sanguis Draxonis dispelling cold by warming the meridian are minister.Scorpio, stir-baked SQUAMA MANITIS, Holotrichia diomphalia Bates reducing swelling and alleviating pain, expellingging wind and relieving convulsion is assistant, Olibanum, Myrrha anti-inflammatory analgetic are for making.All medicines share the chapter of benefiting mutually, play the merit of warming the meridian blood stasis dispelling, wind dispelling cold expelling, channels-freeing dampness-dispelling, anti-inflammatory analgetic altogether.
Good effect of the present invention is:
1, the present invention has good effect, and instant effect is easy to use, the characteristics of compatibility safety; Its function is promoting the flow of QI in the collateral by warming the meridian, blood circulation promoting and blood stasis dispelling, evil-wind expelling and dampness removing, anti-inflammatory analgetic, improves function of joint etc.
2, this formula for a product and preparation technology are simple, and the patent medicine cost is low, are applicable to that rural area, mountain area shortage of medical services and medicines crowd use.
3, the present invention is with pure Chinese medicine processing, have no side effect, no pain during use, it has avoided patient to take medicine for a long time, and trouble of having an injection and misery make medicine absorb through lesions position by dermal osmosis, paste with obvious curative effects was promptly arranged in 3 hours, moreover can paste usefulness repeatedly again, the effect time reached more than 20 days, was that other plaster institute is inaccessiable.
4, effect duration of the present invention long, effective, its processing has overcome the fried processing method of traditional usefulness, causes the deficiency of drug effect forfeiture.
5, the present invention is in 500 routine cases, and clinical recovery 433 examples account for 86.6%, and 48 examples that take a turn for the better account for 9.6%, and invalid 19 examples account for 38%, and total effective rate is 96.26%.
6, the present invention is through external<90 day〉to the rat general activity, outward appearance, diet, the rat hemogram, the section of hepatic and renal function and liver, the heart, spleen, brain, stomach, intestinal main organs and medication local organization all has no adverse effects.
The specific embodiment:
The present invention is described in further detail below in conjunction with embodiment:
Embodiment one:
A kind of plaster that is used for the treatment of rheumatic hyperosteogeny, it is that preparation of raw material by the following weight component forms: give birth to Semen Strychni 60g, Radix Aconiti 75g, Radix Aconiti Kusnezoffii 60g, Scorpio 30g, Cortex Cinnamomi 30g, Holotrichia diomphalia Bates 30g, Sanguis Draxonis 30g, Olibanum 45g, Myrrha 45g, stir-baked SQUAMA MANITIS 30g, Herba Asari 45g.
Its preparation method may further comprise the steps:
The first step, by formulation weight with Sanguis Draxonis 30g, Olibanum 45g, do not have crude drug 45g singly to grind 80 order fine powders respectively, be made as A material;
Second step, by formulation weight will give birth to Semen Strychni 60g, Radix Aconiti 75g, Radix Aconiti Kusnezoffii 60g, Scorpio 30g, Cortex Cinnamomi 30g, Holotrichia diomphalia Bates 30g, stir-baked SQUAMA MANITIS 30g, Herba Asari 45g are crushed to 80 orders, are made as the B material;
The 3rd step, PM-2C medical resin 100g and 45g Colophonium are placed on vessel in heating, after waiting to dissolve into liquid, earlier the B material is added stir after, again the A material is added, and stirs, be made as the C material;
The 4th goes on foot, the C that makes is expected, spread out and spare on the calico of 13 * 13cm, the thickness of C material is 3mm, and its area covers the strippable paper of 13 * 13cm then apart from calico edge 1cm on the C material, push with glass plate, is the plaster that is used for the treatment of rheumatic hyperosteogeny.
Clinical observation, its result is as follows:
Typical case's case history:
Example 1: Wang Damin, man 62 years old, to suffer from left side scapulohumeral periarthritis 1 year surplus because of rheumatism, and pain is heavy light night in daytime, and upper limb can not go up that to lift March surplus, and only a plaster pasted after 20 days, the shoulder activity freely, symptom disappears entirely.
Example 2: Li Zhangyun, woman, 53 years old, suffer from right kneecap hyperosteogeny because of rheumatism, sharp ache can not be walked, paste a plaster after 3 days symptom be clearly better, can walk, symptom disappears entirely behind the first quarter moon, check does not have outbreak after 3 years.
Example 3: Yang Wenyi, woman, 62 years old, two knee joint suffer from rheumatism, proliferative arthritis, and two knee joints can not be squatted down, and increase the weight of during Changes in weather, and bilateral respectively pastes 2 plaster, and pain disappears after one month, and be flexibly movable, and check does not have recurrence after 3 years.
Example 4: Lou Yuxian, woman, 50 years old, because of rheumatism causes lumbar vertebra hyperosteogeny, increase the weight of night, the multi-treatment heterodyne pastes 2 plaster, transference cure after January.
Example 5: permitted mountain of papers, man, 46 years old, duplex, knee joint and suffered from the rheumatic arthritis several years, its joint deformity, be afraid of cool, swell and ache, respectively paste 3 plaster, transference cure after two months.

Claims (4)

1. plaster that is used for the treatment of rheumatic hyperosteogeny is characterized in that: it is that preparation of raw material by the following weight component forms: give birth to 50~70 parts of Semen Strychnis, 60~85 parts of Radix Aconiti, 50~70 parts of Radix Aconiti Kusnezoffii, 20~30 parts of Scorpios, 20~30 parts of Cortex Cinnamomis, 20~40 parts of Holotrichia diomphalia Batess, 20~40 parts of Sanguis Draxonis, 40~50 parts of Olibanum, 40~50 parts of Myrrha, 20~40 parts of stir-baked SQUAMA MANITISs, 40~50 parts of Herba Asaris.
2. the plaster that is used for the treatment of rheumatic hyperosteogeny according to claim 1 is characterized in that: it is that preparation of raw material by the following weight component forms: give birth to 60 parts of Semen Strychnis, 75 parts of Radix Aconiti, 60 parts of Radix Aconiti Kusnezoffii, 30 parts of Scorpios, 30 parts of Cortex Cinnamomis, 30 parts of Holotrichia diomphalia Batess, 30 parts of Sanguis Draxonis, 45 parts of Olibanum, 45 parts of Myrrha, 30 parts of stir-baked SQUAMA MANITISs, 45 parts of Herba Asaris.
3. the preparation method that is used for the treatment of the rheumatic hyperosteogeny plaster according to claim 1 is characterized in that: it is that preparation of raw material by the following weight component forms: give birth to 50~70 parts of Semen Strychnis, 60~85 parts of Radix Aconiti, 50~70 parts of Radix Aconiti Kusnezoffii, 20~30 parts of Scorpios, 20~30 parts of Cortex Cinnamomis, 20~40 parts of Holotrichia diomphalia Batess, 20~40 parts of Sanguis Draxonis, 40~50 parts of Olibanum, 40~50 parts of Myrrha, 20~40 parts of stir-baked SQUAMA MANITISs, 40~50 parts of Herba Asaris;
Its preparation method may further comprise the steps:
The first step, by formulation weight with Sanguis Draxonis, Olibanum, do not have crude drug singly to grind 80 order fine powders respectively, be made as A material;
Second step, will give birth to Semen Strychni, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Cortex Cinnamomi, Holotrichia diomphalia Bates, stir-baked SQUAMA MANITIS, Herba Asari by formulation weight and be crushed to 80 order fine powders, be made as the B material;
The 3rd step, 100 parts of resins and 45 parts of Colophonium are placed on vessel in heating, after waiting to be fused into liquid, the B material are added stir earlier, and then the A material added stir, be made as the C material;
The 4th goes on foot, the C that makes is expected, spread out and spare on the calico of 13 * 13cm, the thickness of C material is 3mm, and its area covers the release paper of 13 * 13cm then apart from calico edge 1cm on the C material, push with glass plate, is the plaster that is used for the treatment of rheumatic hyperosteogeny.
4. the preparation method that is used for the treatment of the rheumatic hyperosteogeny plaster according to claim 3 is characterized in that: the 3rd step, described resin was to adopt the PM-2C resin, was medical resin.
CN2009102272423A 2009-12-02 2009-12-02 Medicament patch for treating rheumatoid hyperostosis and preparation method thereof Expired - Fee Related CN101703654B (en)

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CN105727226A (en) * 2016-03-07 2016-07-06 王永帮 Cold-expelling damp-clearing traditional Chinese medicinal patch

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