CN101690573B - Production method of fructus monordicae extract with over 60% of mogroside V content - Google Patents
Production method of fructus monordicae extract with over 60% of mogroside V content Download PDFInfo
- Publication number
- CN101690573B CN101690573B CN2009100445589A CN200910044558A CN101690573B CN 101690573 B CN101690573 B CN 101690573B CN 2009100445589 A CN2009100445589 A CN 2009100445589A CN 200910044558 A CN200910044558 A CN 200910044558A CN 101690573 B CN101690573 B CN 101690573B
- Authority
- CN
- China
- Prior art keywords
- fructus momordicae
- fresh fructus
- resin
- monordicae extract
- fructus monordicae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000284 extract Substances 0.000 title claims abstract description 50
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 31
- GHBNZZJYBXQAHG-KUVSNLSMSA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8s,9r,10r,11r,13r,14s,17r)-17-[(2r,5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GHBNZZJYBXQAHG-KUVSNLSMSA-N 0.000 title abstract description 5
- TVJXHJAWHUMLLG-UHFFFAOYSA-N mogroside V Natural products CC(CCC(OC1OC(COC2OC(CO)C(O)C(O)C2OC3OC(CO)C(O)C(O)C3O)C(O)C(O)C1O)C(C)(C)O)C4CCC5(C)C6CC=C7C(CCC(OC8OC(COC9OC(CO)C(O)C(O)C9O)C(O)C(O)C8O)C7(C)C)C6(C)C(O)CC45C TVJXHJAWHUMLLG-UHFFFAOYSA-N 0.000 title abstract description 5
- 239000011347 resin Substances 0.000 claims abstract description 43
- 229920005989 resin Polymers 0.000 claims abstract description 43
- 241001409321 Siraitia grosvenorii Species 0.000 claims abstract description 37
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 36
- 238000007670 refining Methods 0.000 claims abstract description 19
- 238000000605 extraction Methods 0.000 claims abstract description 18
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000003456 ion exchange resin Substances 0.000 claims abstract description 14
- 229920003303 ion-exchange polymer Polymers 0.000 claims abstract description 14
- 235000019605 sweet taste sensations Nutrition 0.000 claims abstract description 12
- 238000004062 sedimentation Methods 0.000 claims abstract description 9
- 238000001694 spray drying Methods 0.000 claims abstract description 8
- 238000005119 centrifugation Methods 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 31
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 30
- 229930182470 glycoside Natural products 0.000 claims description 20
- 150000002338 glycosides Chemical class 0.000 claims description 20
- 239000012141 concentrate Substances 0.000 claims description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- 239000002994 raw material Substances 0.000 claims description 11
- 108010089934 carbohydrase Proteins 0.000 claims description 9
- 230000006837 decompression Effects 0.000 claims description 9
- 239000008213 purified water Substances 0.000 claims description 9
- 230000002745 absorbent Effects 0.000 claims description 5
- 239000002250 absorbent Substances 0.000 claims description 5
- 238000009413 insulation Methods 0.000 claims description 5
- 239000003957 anion exchange resin Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 238000010790 dilution Methods 0.000 claims description 3
- 239000012895 dilution Substances 0.000 claims description 3
- 239000003480 eluent Substances 0.000 claims description 3
- 238000012856 packing Methods 0.000 claims description 3
- 238000013467 fragmentation Methods 0.000 claims description 2
- 238000006062 fragmentation reaction Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 16
- 239000000203 mixture Substances 0.000 abstract description 11
- 239000000463 material Substances 0.000 abstract description 8
- 230000008569 process Effects 0.000 abstract description 7
- 238000009776 industrial production Methods 0.000 abstract 2
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 13
- 238000000926 separation method Methods 0.000 description 7
- 238000001179 sorption measurement Methods 0.000 description 7
- 239000004480 active ingredient Substances 0.000 description 6
- 229930182490 saponin Natural products 0.000 description 6
- 235000017709 saponins Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 229920001277 pectin Polymers 0.000 description 5
- 235000010987 pectin Nutrition 0.000 description 5
- 239000001814 pectin Substances 0.000 description 5
- 239000000049 pigment Substances 0.000 description 5
- 229930006000 Sucrose Natural products 0.000 description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 239000002932 luster Substances 0.000 description 4
- 238000005457 optimization Methods 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 238000000746 purification Methods 0.000 description 4
- 150000007949 saponins Chemical class 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000005720 sucrose Substances 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 description 2
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 241000234435 Lilium Species 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 150000001450 anions Chemical class 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000001926 lymphatic effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000001835 salubrious effect Effects 0.000 description 2
- -1 saponins compound Chemical class 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- KEQXNNJHMWSZHK-UHFFFAOYSA-L 1,3,2,4$l^{2}-dioxathiaplumbetane 2,2-dioxide Chemical compound [Pb+2].[O-]S([O-])(=O)=O KEQXNNJHMWSZHK-UHFFFAOYSA-L 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 235000009815 Momordica Nutrition 0.000 description 1
- 241000218984 Momordica Species 0.000 description 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- ZYZJWAJOTPNVPI-ZVBSCDOUSA-N cucurbitane Chemical compound C([C@H]1[C@]2(C)CC[C@@H]([C@]2(CC[C@]11C)C)[C@H](C)CCCC(C)C)CC2[C@H]1CCCC2(C)C ZYZJWAJOTPNVPI-ZVBSCDOUSA-N 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000004042 decolorization Methods 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 125000003147 glycosyl group Chemical group 0.000 description 1
- 230000013595 glycosylation Effects 0.000 description 1
- 238000006206 glycosylation reaction Methods 0.000 description 1
- 208000021822 hypotensive Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 229930189775 mogroside Natural products 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001603 reducing effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 description 1
- 150000003648 triterpenes Chemical group 0.000 description 1
- 150000008130 triterpenoid saponins Chemical class 0.000 description 1
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009100445589A CN101690573B (en) | 2009-10-16 | 2009-10-16 | Production method of fructus monordicae extract with over 60% of mogroside V content |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009100445589A CN101690573B (en) | 2009-10-16 | 2009-10-16 | Production method of fructus monordicae extract with over 60% of mogroside V content |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101690573A CN101690573A (en) | 2010-04-07 |
CN101690573B true CN101690573B (en) | 2012-01-25 |
Family
ID=42079324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009100445589A Active CN101690573B (en) | 2009-10-16 | 2009-10-16 | Production method of fructus monordicae extract with over 60% of mogroside V content |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101690573B (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ549739A (en) | 2006-09-07 | 2009-01-31 | Biovittoria Ltd | Sweetening compositions and processes for preparing them |
US8962698B2 (en) | 2011-01-28 | 2015-02-24 | Tate & Lyle Ingredients Americas Llc | Rebaudioside-mogroside V blends |
US9402411B2 (en) | 2011-01-28 | 2016-08-02 | Tate & Lyle Ingredients Americas Llc | Stevia blends containing rebaudioside B |
CN102356865A (en) * | 2011-09-19 | 2012-02-22 | 桂林莱茵生物科技股份有限公司 | Sweetener and preparation method thereof |
GB201217700D0 (en) | 2012-08-01 | 2012-11-14 | Tate & Lyle Ingredients | Sweetener compositions containing rebaudioside B |
DK3138412T3 (en) * | 2012-08-07 | 2019-07-22 | Guilin Gfs Monk Fruit Corp | PROCEDURE FOR PREPARING SWEET SOFT COMPOSITIONS |
CN104059959A (en) * | 2013-03-20 | 2014-09-24 | 广西壮族自治区中国科学院广西植物研究所 | Method for synthesizing sweet saponin with bitter and fallen grosvenor momordica fruit as raw material |
CN103461952A (en) * | 2013-09-24 | 2013-12-25 | 张雨生 | Fresh momordica grosvenori aspartame containing non-damaged fresh momordica grosvenori health-care components and preparation method thereof |
CN103800422B (en) * | 2014-01-22 | 2018-04-10 | 湖南农业大学 | Compound electuary preparation of eucommia health care and products thereof |
CN106008645B (en) | 2016-06-06 | 2017-12-15 | 江西海富生物工程有限公司 | A kind of method that momordica grosvenori glycoside V is extracted from Momordica grosvenori |
EP3528646B1 (en) | 2016-10-24 | 2024-04-03 | Guilin GFS Monk Fruit Corporation | Extracts from fruits of the cucurbitaceae family, and methods of preparing thereof |
CN108276465B (en) * | 2017-03-14 | 2020-01-07 | 桂林莱茵生物科技股份有限公司 | Method for separating and purifying mogroside V by subcritical water desorption technology |
CN106943447A (en) * | 2017-04-01 | 2017-07-14 | 成都普睿法药物研发有限公司 | A kind of preparation method of Fructus Monordicae extract |
CN107936079B (en) * | 2017-11-28 | 2020-05-01 | 河南中大恒源生物科技股份有限公司 | Method for preparing high-purity mogroside V |
CN109247561A (en) * | 2018-09-06 | 2019-01-22 | 湖南绿蔓生物科技股份有限公司 | A kind of method and its application preparing Siraitia grosvenorii sweetener composition from Siraitia grosvenorii |
CN111978365B (en) * | 2020-09-10 | 2022-04-12 | 上海诺德生物实业有限公司 | Preparation method of mogroside V-containing mogroside |
CN113861260A (en) * | 2021-09-07 | 2021-12-31 | 桂林三棱生物科技有限公司 | Preparation method of momordica grosvenori sweet glycoside compounds |
CN113854533B (en) * | 2021-09-30 | 2023-09-05 | 湖南华诚生物资源股份有限公司 | A method for preparing mogroside, mogrolic acid, fructus Siraitiae Grosvenorii concentrated juice and fructus Siraitiae Grosvenorii fructose from fresh fructus Siraitiae Grosvenorii |
CN115109112B (en) * | 2022-08-10 | 2024-03-15 | 刘庚贵 | Industrial production method of mogroside for improving content of mogroside V |
-
2009
- 2009-10-16 CN CN2009100445589A patent/CN101690573B/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN101690573A (en) | 2010-04-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101690573B (en) | Production method of fructus monordicae extract with over 60% of mogroside V content | |
CN106008645B (en) | A kind of method that momordica grosvenori glycoside V is extracted from Momordica grosvenori | |
CN100572552C (en) | Fructus Monordicae extract of momordica grosvenori glycoside V content 〉=40% and preparation method thereof | |
CN105272988B (en) | A kind of pool extracting method of mulberry leaf active ingredient | |
CN105193863B (en) | A kind of preparation method of high-purity seeweed polyphenol | |
CN109247561A (en) | A kind of method and its application preparing Siraitia grosvenorii sweetener composition from Siraitia grosvenorii | |
CN108516997A (en) | A method of extracting Rubusoside from sweet tea | |
CN102702284A (en) | Production process of high-purity sweet tea glycosides | |
CN105294790A (en) | Method for extracting high-purity steviol glycosides from stevia rebaudiana | |
CN108752231B (en) | Method for extracting theanine from sweet tea and simultaneously extracting rubusoside and tea polyphenol | |
CN106967142B (en) | Method that is a kind of while extracting momordica glycoside V, VI and 11-O base glycosides V | |
CN106083940A (en) | A kind of method extracting high purity novel aurantiamarin from Fructus Aurantii Immaturus | |
CN102948758A (en) | Method for extracting buckwheat flavone from buckwheat bran | |
CN106589010B (en) | Method that is a kind of while producing L-arabinose and D- galactolipin | |
CN101891781A (en) | Method for preparing high-purity gardenoside | |
CN109180755A (en) | A method of extracting Rubusoside from sweet tea | |
CN102180935A (en) | Method for preparing high-purity sasanquasaponins | |
CN101407535B (en) | Preparation of high-purity Momordica grosvenori mogroside V | |
CN109320400A (en) | A method of natural mannitol is extracted from mogroside production waste liquid | |
CN102558254B (en) | Extract of willow barks or willow branches and method for preparing salicin | |
CN107880081A (en) | A kind of synthetic method of isoquercitin | |
CN104292366A (en) | Method for simultaneously extracting arabinogalactan and dihydroquercetin from dahurian larch | |
CN108864238A (en) | The method that arhat fruit seed oil and cupreol are extracted in slag is extracted from Siraitia grosvenorii | |
CN101759731B (en) | Extraction method of linseed gum and secoisolariciresin-ol diglucoside | |
CN1289609C (en) | Method for preparing crystal of lycopene and concentrate |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: HUNAN NUTRAMAX INC. Free format text: FORMER NAME: CHANGSHA NUTRAMAX INC. |
|
CP03 | Change of name, title or address |
Address after: 25 floor, No. 217 Hunan province Changsha Jiahe Pavilion 410016 Wanjiali Road Patentee after: HUNAN NUTRAMAX INC. Address before: 410016 Hunan province Changsha Wanjiali Road No. 219 building 25 Jiahe Ge Ming Fu Hua Zhang Patentee before: Changsha Nutramax Inc. |
|
TR01 | Transfer of patent right |
Effective date of registration: 20170508 Address after: The 425900 Hunan Economic Development Zone of Dongan Province Fang City Industrial Park Patentee after: Hunan sweet Biotechnology Co., Ltd. Address before: 25 floor, No. 217 Hunan province Changsha Jiahe Pavilion 410016 Wanjiali Road Patentee before: HUNAN NUTRAMAX INC. |
|
TR01 | Transfer of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A method for the production of Fructus grosvenori extract with V content of more than 60% Effective date of registration: 20171110 Granted publication date: 20120125 Pledgee: Agricultural Bank of China, Dongan County branch, Limited by Share Ltd Pledgor: Hunan sweet Biotechnology Co., Ltd. Registration number: 2017430000082 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20191113 Granted publication date: 20120125 Pledgee: Agricultural Bank of China, Dongan County branch, Limited by Share Ltd Pledgor: Hunan sweet Biotechnology Co., Ltd. Registration number: 2017430000082 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A production method of extract of Siraitia grosvenorii with content of more than 60% Effective date of registration: 20191125 Granted publication date: 20120125 Pledgee: Bank of Changsha Co., Ltd. Kaifu sub branch Pledgor: Hunan sweet Biotechnology Co., Ltd. Registration number: Y2019430000046 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20201217 Granted publication date: 20120125 Pledgee: Bank of Changsha Co.,Ltd. Kaifu sub branch Pledgor: Hunan sweet Biotechnology Co.,Ltd. Registration number: Y2019430000046 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A method for the production of Fructus grosvenori extract with V content of more than 60% Effective date of registration: 20201218 Granted publication date: 20120125 Pledgee: Bank of Changsha Co.,Ltd. Kaifu sub branch Pledgor: Hunan sweet Biotechnology Co.,Ltd. Registration number: Y2020980009580 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220616 Granted publication date: 20120125 Pledgee: Bank of Changsha Co.,Ltd. Kaifu sub branch Pledgor: Hunan sweet Biotechnology Co.,Ltd. Registration number: Y2020980009580 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |