CN101687152B - 单分散微滴的生成 - Google Patents

单分散微滴的生成 Download PDF

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Publication number
CN101687152B
CN101687152B CN2008800232872A CN200880023287A CN101687152B CN 101687152 B CN101687152 B CN 101687152B CN 2008800232872 A CN2008800232872 A CN 2008800232872A CN 200880023287 A CN200880023287 A CN 200880023287A CN 101687152 B CN101687152 B CN 101687152B
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CN
China
Prior art keywords
fluid
cavity
droplet
flow
jet
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2008800232872A
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English (en)
Chinese (zh)
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CN101687152A (zh
Inventor
A·克拉克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastman Kodak Co
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Eastman Kodak Co
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Filing date
Publication date
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Publication of CN101687152A publication Critical patent/CN101687152A/zh
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4337—Mixers with a diverging-converging cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Nozzles (AREA)
  • Colloid Chemistry (AREA)
CN2008800232872A 2007-07-03 2008-06-27 单分散微滴的生成 Expired - Fee Related CN101687152B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0712863.0A GB0712863D0 (en) 2007-07-03 2007-07-03 Monodisperse droplet generation
GB0712863.0 2007-07-03
PCT/GB2008/002217 WO2009004314A1 (en) 2007-07-03 2008-06-27 Monodisperse droplet generation

Publications (2)

Publication Number Publication Date
CN101687152A CN101687152A (zh) 2010-03-31
CN101687152B true CN101687152B (zh) 2013-02-06

Family

ID=38421116

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008800232872A Expired - Fee Related CN101687152B (zh) 2007-07-03 2008-06-27 单分散微滴的生成

Country Status (6)

Country Link
US (1) US8302880B2 (https=)
EP (1) EP2164617B1 (https=)
JP (1) JP5335784B2 (https=)
CN (1) CN101687152B (https=)
GB (1) GB0712863D0 (https=)
WO (1) WO2009004314A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006096571A2 (en) 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
CN102124259B (zh) 2008-05-16 2015-12-16 哈佛大学 在包含微流体系统的流体系统中的阀和其它流动控制
US8609737B2 (en) * 2008-09-18 2013-12-17 Technische Universiteit Eindhoven Process for preparing monodispersed emulsions
WO2010110843A1 (en) 2009-03-25 2010-09-30 Eastman Kodak Company Droplet generator
WO2011028764A2 (en) 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
FR2958186A1 (fr) 2010-03-30 2011-10-07 Ecole Polytech Dispositif de formation de gouttes dans un circuit microfluide.
CN101994162A (zh) * 2010-12-10 2011-03-30 江南大学 微流体静电纺丝装置
BR112013029729A2 (pt) 2011-05-23 2017-01-24 Basf Se controle de emulsões, incluindo emulsões múltiplas
CN103764265A (zh) 2011-07-06 2014-04-30 哈佛学院院长等 多重乳剂和用于配制多重乳剂的技术
US8936354B2 (en) 2012-03-28 2015-01-20 Eastman Kodak Company Digital drop patterning device and method
US8939551B2 (en) 2012-03-28 2015-01-27 Eastman Kodak Company Digital drop patterning device and method
US8602535B2 (en) 2012-03-28 2013-12-10 Eastman Kodak Company Digital drop patterning device and method
US8936353B2 (en) 2012-03-28 2015-01-20 Eastman Kodak Company Digital drop patterning device and method
GB2502058B (en) * 2012-05-14 2014-08-06 Schlumberger Holdings Determining interfacial tension between first and second immiscible liquids
GB2513310B (en) 2013-04-22 2015-09-16 Schlumberger Holdings Determination of interfacial or surface tension
JP6736553B2 (ja) 2014-12-12 2020-08-05 ゼネラル・エレクトリック・カンパニイ 湿潤ガス流の流れを調整するためのシステムおよび方法
WO2016189383A1 (en) * 2015-05-22 2016-12-01 The Hong Kong University Of Science And Technology Droplet generator based on high aspect ratio induced droplet self-breakup
CN105498869B (zh) * 2015-11-27 2017-06-09 中国石油大学(华东) 一种微纳米液滴制备方法
DE102017105194A1 (de) * 2017-03-10 2018-09-13 Little Things Factory Gmbh Fokussiereinrichtung, Tropfengenerator und Verfahren zum Erzeugen einer Vielzahl von Tröpfchen
CN107029640B (zh) * 2017-05-23 2023-04-21 中国科学技术大学 基于液驱流动聚焦射流扰动的微液滴主动制备装置及方法
AU2019321552A1 (en) 2018-08-17 2021-03-11 The Regents Of The University Of California Monodispersed particle-triggered droplet formation from stable jets
CN111841439A (zh) * 2020-08-19 2020-10-30 中国科学技术大学 一种高通量制备均匀单乳液滴的装置及方法
CN112844895B (zh) * 2021-01-03 2021-08-17 清华大学 一种控制液体射流破碎的装置
CN114749219B (zh) * 2022-03-30 2023-06-02 北京航空航天大学 集成压电式均匀液滴发生器

Citations (2)

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US6347883B1 (en) * 1999-01-26 2002-02-19 Kvaerner Pulping Ab Apparatus for adding a first fluid into a second fluid with means to prevent clogging
DE102005048259A1 (de) * 2005-10-07 2007-04-19 Landesstiftung Baden-Württemberg Vorrichtung und Verfahren zur Erzeugung eines Gemenges von zwei ineinander unlösbaren Phasen

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JPS61138529A (ja) * 1984-12-10 1986-06-26 Idemitsu Petrochem Co Ltd サイズ用乳化液の製造方法
GB9406255D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
US5873523A (en) * 1996-02-29 1999-02-23 Yale University Electrospray employing corona-assisted cone-jet mode
EP1037858A1 (en) 1997-12-17 2000-09-27 Universidad de Sevilla Device and method for creating spherical particles of uniform size
AU745698B2 (en) * 1997-12-17 2002-03-28 Universidad De Sevilla Device and method for aeration of fluids
CA2365847A1 (en) 1999-04-06 2000-10-12 Gregg M. Duthaler Methods for producing droplets for use in capsule-based electrophoretic displays
WO2002023163A1 (en) 2000-09-15 2002-03-21 California Institute Of Technology Microfabricated crossflow devices and methods
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
AU2004229440B2 (en) * 2003-04-10 2010-08-12 President And Fellows Of Harvard College Formation and control of fluidic species
WO2005021151A1 (en) * 2003-08-27 2005-03-10 President And Fellows Of Harvard College Electronic control of fluidic species
EP1742979A4 (en) 2004-04-23 2008-05-21 Eugenia Kumacheva METHOD FOR PRODUCING POLYMER PARTICLES OF SELECTED SIZE, MOLD, MORPHOLOGY AND COMPOSITION
US7759111B2 (en) * 2004-08-27 2010-07-20 The Regents Of The University Of California Cell encapsulation microfluidic device
US20060234051A1 (en) * 2005-01-27 2006-10-19 Zhang Wendy W System and method of obtaining entrained cylindrical fluid flow
WO2006096571A2 (en) 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
JP4713397B2 (ja) * 2006-01-18 2011-06-29 株式会社リコー 微小流路構造体及び微小液滴生成システム
JP2008100182A (ja) * 2006-10-20 2008-05-01 Hitachi Plant Technologies Ltd 乳化装置および微粒子製造装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6347883B1 (en) * 1999-01-26 2002-02-19 Kvaerner Pulping Ab Apparatus for adding a first fluid into a second fluid with means to prevent clogging
DE102005048259A1 (de) * 2005-10-07 2007-04-19 Landesstiftung Baden-Württemberg Vorrichtung und Verfahren zur Erzeugung eines Gemenges von zwei ineinander unlösbaren Phasen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
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Also Published As

Publication number Publication date
WO2009004314A1 (en) 2009-01-08
JP5335784B2 (ja) 2013-11-06
EP2164617B1 (en) 2013-03-27
GB0712863D0 (en) 2007-08-08
US20100170957A1 (en) 2010-07-08
JP2010531730A (ja) 2010-09-30
US8302880B2 (en) 2012-11-06
EP2164617A1 (en) 2010-03-24
CN101687152A (zh) 2010-03-31

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Granted publication date: 20130206

Termination date: 20180627