CN101670019B - Complex preparation having radiation-resisting and eyesight-protecting functions - Google Patents

Complex preparation having radiation-resisting and eyesight-protecting functions Download PDF

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Publication number
CN101670019B
CN101670019B CN2008102120178A CN200810212017A CN101670019B CN 101670019 B CN101670019 B CN 101670019B CN 2008102120178 A CN2008102120178 A CN 2008102120178A CN 200810212017 A CN200810212017 A CN 200810212017A CN 101670019 B CN101670019 B CN 101670019B
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tea
seed oil
radiation
coenzyme
eyesight
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CN2008102120178A
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CN101670019A (en
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郑侠慧
李兴发
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Abstract

The invention relates to a complex preparation having radiation-resisting and eyesight-protecting functions, which comprises the following components in percentage by weight: 65 to 98 percent of tea seed oil, 0.15 to 15.0 percent of coenzyme Q10, 0.05 to 10.0 percent of lutein, 0.10 to 10.0 percent of alpha-lipoic acid and 0.01 to 0.10 percent of vitamin A. The tea seed oil is grease obtained by picking and shelling mature seeds of tea trees, drying the shelled tee seeds by hot air at a temperature of between 100 and 110 DEG C until constant weight is achieved, smashing the tee seeds and extracting the tee seeds by using supercritical carbon dioxide. The five components are mixed organically to obtain an efficient radiation-resisting and eyesight-protecting product, so that defects of related products in the current market are solved skillfully. The complex preparation having the radiation-resisting and eyesight-protecting functions is particularly suitable for a wide range of people exposed under radiation environment and is a health-care food with the functions of preventing and repairing damages, protecting the eyesight and relieving asthenopia.

Description

A kind of compound formulation with radioprotective and vision protection function
Technical field
The present invention relates to field of health care food; particularly relate to a kind of compound formulation with radioprotective and vision protection function, said preparation has the effect of good radioprotective and vision protection for the people of work under electromagnetic radiation (as computer, TV, mobile phone, Aeronautics and Astronautics, plateau, polar region etc.) environment and life.
Background technology
Along with progress of science and technology, existent environment of people more and more is subjected to the universal load that has more increased the weight of human body radiation dosage of the prestige association, particularly equipment such as computer, TV, mobile communication of radiation pollution, causes chronic injury in various degree.This is to cause human body to be in one of key factor of sub-health state, its direct consequence is to make people's inefficiency of working, the mental status is dispirited, long term effect can make body that a series of biochemical reactions take place, as cause organism metabolic disorder, cause DNA damage when serious, bring out the sharp increase of cell micronucleus rate, chromosomal aberration, gene mutation even carcinogenesis.Electromagnetic radiation meanwhile also can cause asthenopia, causes visual deterioration, uses computer especially for a long time and watches crowd's performance of TV more outstanding.Therefore, the radiation damage studies on Protective Measures has become the heat subject of current research, protection approaches is except physical method and medical protection, and radiation-resisting functional food will have been realized the purpose that reduces radiation damage or radiation damage is effectively repaired with its convenient, nontoxic, regular characteristics such as take.For example Granted publication number is the described a kind of ginkgetin of Chinese patent of CN1282455C and the antiradiation drug of tea polyphenols combination.And for example, the health preparation made of the medical material that from Chinese herbal medicine, screens for the described use of Chinese patent of CN 1061540C of Granted publication number with radiation resistance.But, still not having at present and not only have radiation proof function but also health food or a medicine that can alleviating asthenopia, the present invention produces under this background.
Summary of the invention
The present invention is directed to the deficiency of having only single radioprotective or vision protection product in the market; providing a kind of is raw material with tea-seed oil, coenzyme Q10, phylloxanthin, alpha-lipoic acid, vitamin A; cooperate the efficient compound formulation that not only has radiation-resisting functional but also have the vision protection function form by a certain percentage, said preparation can be made soft capsule or drop pill.
Concrete technical scheme of the present invention is as follows:
A kind of compound formulation with radioprotective and vision protection function; by weight, its prescription is: tea-seed oil: 65~98%, coenzyme Q10: 0.15~15.0%, phylloxanthin: 0.05~10.0%, alpha-lipoic acid: 0.10~10.0%, vitamin A: 0.01~0.10%.
Described tea-seed oil is to shell after the mature seed of Folium Camelliae sinensis tree is plucked, and, pulverizes, by the oils and fats of supercritical carbon dioxide extraction gained to constant weight in 100~110 ℃ of following hot air dryings.Described tea-seed oil also can be commercially available product.
Compound formulation of the present invention mixes by five kinds of above-mentioned raw materials being reached according to a certain percentage sequencing, crosses homogenizer or colloid mill, is made into soft capsule or drop pill.
Described coenzyme Q10, phylloxanthin, alpha-lipoic acid and vitamin A all are the commercially available prod, and its manufacturer can obtain by the google query site.
Outstanding feature of the present invention is to utilize supercritical carbon dioxide extraction method to obtain to be rich in the tea-seed oil of fat-soluble tea polyphenol, and it has very strong radiation-resisting functional.Because the electromagnetic radiation meeting causes the oxidative damage of body, the most direct position is the macular area of eyes, in the course of time can cause asthenopia even visual deterioration, coenzyme Q10 in the prescription is the ingredient of cell mitochondrial electron transport chain, participate in oxidative phosphorylation, can remove radiation-induced free radical; Alpha-lipoic acid also is a kind of coenzyme, is requisite in the mitochondrion generation ATP process, is degraded to dihydrolipoic acid in mitochondrion, and its anti-oxidation function is more powerful, and the two synergism can suppress the oxidative damage that this electromagnetic radiation causes effectively.In addition, phylloxanthin is present in the macular area of blood plasma and eyes in human body, except that having anti-oxidation function, as light protection composition, causes the blue light of retina injury effectively in the filtering sunlight, prevents visual deterioration and blind disease; Vitamin A claims retinol again, and the integrity of keeping vision and protection cell membrane is played an important role, and its biochemical action and visual function relation are very close.The present invention is by organic cooperation of above-mentioned five kinds of compositions; a kind of radioprotective efficiently and vision protection product have been formed; this product has solved the deficiency that the existing market Related product exists dexterously; being particularly suitable for being exposed to the numerous crowds under the radiation environment, is a kind ofly to have protection and repair damage and the health food of vision protection, asthenopia releasing function.
The specific embodiment
Embodiment 1
By tea-seed oil: coenzyme Q10 98.00%: phylloxanthin 0.15%: alpha-lipoic acid 0.05%: vitamin A 1.79%: 0.01% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross colloid mill, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 2
By tea-seed oil: coenzyme Q10 96.00%: phylloxanthin 2.10%: alpha-lipoic acid 0.35%: vitamin A 1.53%: 0.02% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 3
By tea-seed oil: coenzyme Q10 94.00%: phylloxanthin 3.25%: alpha-lipoic acid 0.55%: vitamin A 2.17%: 0.03% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross colloid mill, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 4
By tea-seed oil: coenzyme Q10 92.00%: phylloxanthin 5.40%: alpha-lipoic acid 1.55%: vitamin A 1.00%: 0.05% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 5
By tea-seed oil: coenzyme Q10 90.00%: phylloxanthin 8.60%: alpha-lipoic acid 1.24%: vitamin A 0.10%: 0.06% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross colloid mill, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 6
By tea-seed oil: coenzyme Q10 87.80%: phylloxanthin 7.20%: alpha-lipoic acid 1.74%: vitamin A 3.21%: 0.05% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross colloid mill, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 7
By tea-seed oil: coenzyme Q10 86.70%: phylloxanthin 6.57%: alpha-lipoic acid 2.16%: vitamin A 4.52%: 0.05% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 8
By tea-seed oil: coenzyme Q10 84.00%: phylloxanthin 9.09%: alpha-lipoic acid 2.35%: vitamin A 4.51%: 0.05% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 9
By tea-seed oil: coenzyme Q10 82.56%: phylloxanthin 9.29%: alpha-lipoic acid 4.88%: vitamin A 3.21%: 0.06% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 10
By tea-seed oil: coenzyme Q10 78.15%: phylloxanthin 10.50%: alpha-lipoic acid 5.85%: vitamin A 5.43%: 0.07% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 11
By tea-seed oil: coenzyme Q10 75.60%: phylloxanthin 11.20%: alpha-lipoic acid 6.71%: vitamin A 6.42%: 0.07% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 12
By tea-seed oil: coenzyme Q10 73.00%: phylloxanthin 11.70%: alpha-lipoic acid 7.30%: vitamin A 7.92%: 0.08% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 13
By tea-seed oil: coenzyme Q10 70.30%: phylloxanthin 12.20%: alpha-lipoic acid 8.62%: vitamin A 8.80%: 0.08% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 14
By tea-seed oil: coenzyme Q10 67.00%: phylloxanthin 13.60%: alpha-lipoic acid 9.31%: vitamin A 10.00%: 0.09% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.
Embodiment 15
By tea-seed oil: coenzyme Q10 65.00%: phylloxanthin 15.00%: alpha-lipoic acid 10.00%: vitamin A 9.90%: 0.10% takes by weighing raw material respectively, with the tea-seed oil separated into two parts, wherein a part is mixed with coenzyme Q10 under the condition of lucifuge, another part mixes one by one with all the other raw materials respectively, allow its dissolving, then under the condition of lucifuge with the two mix homogeneously, cross homogenizer, be loaded in the stainless steel cask, be processed into capsule or drop pill by technological process of the prior art.

Claims (3)

1. compound formulation with radioprotective and vision protection function, by weight, its prescription is:
Tea-seed oil: 65~98%;
Coenzyme Q10: 0. 15~15.0%;
Phylloxanthin: 0. 05~10.0%;
Alpha-lipoic acid: 0. 10~10.0%;
Vitamin A: 0. 01~0.10%.
2. compound formulation according to claim 1 is characterized in that, described tea-seed oil is to shell after the mature seed of Folium Camelliae sinensis tree is plucked, and, pulverizes, by the oils and fats of supercritical carbon dioxide extraction gained to constant weight in 100~110 ℃ of following hot air dryings.
3. compound formulation according to claim 1 and 2 is characterized in that described compound formulation can be made into soft capsule or drop pill.
CN2008102120178A 2008-09-11 2008-09-11 Complex preparation having radiation-resisting and eyesight-protecting functions Expired - Fee Related CN101670019B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102511800B (en) * 2011-12-15 2013-08-14 厦门鹰君药业有限公司 Health-care food capsule and preparation method thereof
CN104824644A (en) * 2015-05-13 2015-08-12 宁波北仑戌鸿农业科技有限公司 Food suitable for vision protection
WO2021107106A1 (en) * 2019-11-29 2021-06-03 ロート製薬株式会社 Oral composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1524448A (en) * 2003-02-27 2004-09-01 郑春山 Nutritious health-care food for protecting eyes and producing method therefor
CN101173205A (en) * 2007-12-03 2008-05-07 黄宝生 Skin-protection soap of tea seed oil
CN101229287A (en) * 2007-11-02 2008-07-30 郭富凤 Polynary lycopene preventing and treating eye disease capsule and preparing method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1524448A (en) * 2003-02-27 2004-09-01 郑春山 Nutritious health-care food for protecting eyes and producing method therefor
CN101229287A (en) * 2007-11-02 2008-07-30 郭富凤 Polynary lycopene preventing and treating eye disease capsule and preparing method thereof
CN101173205A (en) * 2007-12-03 2008-05-07 黄宝生 Skin-protection soap of tea seed oil

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
曾益坤.茶叶籽制油及综合开发利用.《中国油脂》.2006,第31卷(第1期),第69-71页. *

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