CN101664533B - Chinese medicament for treating acute and chronic mammary hyperplasia and preparation method - Google Patents
Chinese medicament for treating acute and chronic mammary hyperplasia and preparation method Download PDFInfo
- Publication number
- CN101664533B CN101664533B CN 200810051138 CN200810051138A CN101664533B CN 101664533 B CN101664533 B CN 101664533B CN 200810051138 CN200810051138 CN 200810051138 CN 200810051138 A CN200810051138 A CN 200810051138A CN 101664533 B CN101664533 B CN 101664533B
- Authority
- CN
- China
- Prior art keywords
- parts
- portions
- radix
- chinese
- chronic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 39
- 206010020718 hyperplasia Diseases 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 230000001684 chronic effect Effects 0.000 title claims abstract description 12
- 230000001154 acute effect Effects 0.000 title claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 238000001035 drying Methods 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 5
- 238000005453 pelletization Methods 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 229920002472 Starch Polymers 0.000 claims abstract description 3
- 239000000314 lubricant Substances 0.000 claims abstract description 3
- 239000008107 starch Substances 0.000 claims abstract description 3
- 235000019698 starch Nutrition 0.000 claims abstract description 3
- 229940079593 drug Drugs 0.000 claims description 15
- 238000010298 pulverizing process Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 241000407170 Curcuma Species 0.000 claims description 5
- 235000014375 Curcuma Nutrition 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 3
- 230000002829 reductive effect Effects 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 239000012567 medical material Substances 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 20
- 230000000694 effects Effects 0.000 abstract description 9
- 239000000203 mixture Substances 0.000 abstract description 8
- 239000000284 extract Substances 0.000 abstract description 6
- 230000002124 endocrine Effects 0.000 abstract description 3
- 230000009467 reduction Effects 0.000 abstract description 3
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 2
- 229940011871 estrogen Drugs 0.000 abstract description 2
- 239000000262 estrogen Substances 0.000 abstract description 2
- 241000675108 Citrus tangerina Species 0.000 abstract 3
- 241000213006 Angelica dahurica Species 0.000 abstract 2
- 244000163122 Curcuma domestica Species 0.000 abstract 2
- 235000003392 Curcuma domestica Nutrition 0.000 abstract 2
- 244000150195 Cyperus longus Species 0.000 abstract 2
- 235000018109 Cyperus longus Nutrition 0.000 abstract 2
- 244000075634 Cyperus rotundus Species 0.000 abstract 2
- 241000935235 Fritillaria meleagris Species 0.000 abstract 2
- 235000005010 Scirpus paludosus Nutrition 0.000 abstract 2
- 240000001949 Taraxacum officinale Species 0.000 abstract 2
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 2
- 235000008326 Trichosanthes anguina Nutrition 0.000 abstract 2
- 244000078912 Trichosanthes cucumerina Species 0.000 abstract 2
- 235000003373 curcuma longa Nutrition 0.000 abstract 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 235000013976 turmeric Nutrition 0.000 abstract 2
- 244000236521 Bupleurum rotundifolium Species 0.000 abstract 1
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 239000000469 ethanolic extract Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 206010012335 Dependence Diseases 0.000 description 29
- 241000700159 Rattus Species 0.000 description 29
- 210000004369 blood Anatomy 0.000 description 16
- 239000008280 blood Substances 0.000 description 16
- 241000699670 Mus sp. Species 0.000 description 11
- 230000002401 inhibitory effect Effects 0.000 description 10
- 210000004185 liver Anatomy 0.000 description 10
- 210000005075 mammary gland Anatomy 0.000 description 10
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 9
- 201000010099 disease Diseases 0.000 description 9
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 8
- 210000000481 breast Anatomy 0.000 description 7
- 240000001624 Espostoa lanata Species 0.000 description 6
- 235000009161 Espostoa lanata Nutrition 0.000 description 6
- 206010020880 Hypertrophy Diseases 0.000 description 6
- 208000035475 disorder Diseases 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 210000002445 nipple Anatomy 0.000 description 6
- -1 Dichlorodiphenyl Acetate Chemical compound 0.000 description 5
- 241000699666 Mus <mouse, genus> Species 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000003203 everyday effect Effects 0.000 description 5
- 230000001575 pathological effect Effects 0.000 description 5
- 210000004291 uterus Anatomy 0.000 description 5
- 206010063560 Excessive granulation tissue Diseases 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 230000002496 gastric effect Effects 0.000 description 4
- 210000001126 granulation tissue Anatomy 0.000 description 4
- 238000001802 infusion Methods 0.000 description 4
- 239000013641 positive control Substances 0.000 description 4
- 208000037920 primary disease Diseases 0.000 description 4
- 239000000186 progesterone Substances 0.000 description 4
- 229960003387 progesterone Drugs 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 238000004080 punching Methods 0.000 description 4
- 230000028327 secretion Effects 0.000 description 4
- 239000003826 tablet Substances 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 3
- UYIFTLBWAOGQBI-BZDYCCQFSA-N Benzhormovarine Chemical compound C([C@@H]1[C@@H](C2=CC=3)CC[C@]4([C@H]1CC[C@@H]4O)C)CC2=CC=3OC(=O)C1=CC=CC=C1 UYIFTLBWAOGQBI-BZDYCCQFSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 239000002671 adjuvant Substances 0.000 description 3
- 208000030270 breast disease Diseases 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 230000008508 epithelial proliferation Effects 0.000 description 3
- 229950002007 estradiol benzoate Drugs 0.000 description 3
- 239000003172 expectorant agent Substances 0.000 description 3
- 230000003419 expectorant effect Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 230000036407 pain Effects 0.000 description 3
- 230000008506 pathogenesis Effects 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- 241000721047 Danaus plexippus Species 0.000 description 2
- 239000009636 Huang Qi Substances 0.000 description 2
- 241000700157 Rattus norvegicus Species 0.000 description 2
- 230000002146 bilateral effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000023555 blood coagulation Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 210000005069 ears Anatomy 0.000 description 2
- 238000002481 ethanol extraction Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000010255 intramuscular injection Methods 0.000 description 2
- 239000007927 intramuscular injection Substances 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- 240000006409 Acacia auriculiformis Species 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010006298 Breast pain Diseases 0.000 description 1
- 241000459479 Capsula Species 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 206010013183 Dislocation of vertebra Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010018691 Granuloma Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- 102000009151 Luteinizing Hormone Human genes 0.000 description 1
- 108010073521 Luteinizing Hormone Proteins 0.000 description 1
- 208000006662 Mastodynia Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 208000031816 Pathologic Dilatation Diseases 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- 241000238370 Sepia Species 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 241000053227 Themus Species 0.000 description 1
- 238000008050 Total Bilirubin Reagent Methods 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- 208000038016 acute inflammation Diseases 0.000 description 1
- 230000006022 acute inflammation Effects 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
- 229960000723 ampicillin Drugs 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 239000008840 bushen tiaochong Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000004320 controlled atmosphere Methods 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 229960005309 estradiol Drugs 0.000 description 1
- 229930182833 estradiol Natural products 0.000 description 1
- 206010016629 fibroma Diseases 0.000 description 1
- 239000007941 film coated tablet Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000007952 growth promoter Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000002390 hyperplastic effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000000854 inhibitional effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 231100001252 long-term toxicity Toxicity 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000003305 oral gavage Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000000505 pernicious effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200810051138 CN101664533B (en) | 2008-09-04 | 2008-09-04 | Chinese medicament for treating acute and chronic mammary hyperplasia and preparation method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200810051138 CN101664533B (en) | 2008-09-04 | 2008-09-04 | Chinese medicament for treating acute and chronic mammary hyperplasia and preparation method |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101664533A CN101664533A (en) | 2010-03-10 |
CN101664533B true CN101664533B (en) | 2013-04-03 |
Family
ID=41801415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200810051138 Active CN101664533B (en) | 2008-09-04 | 2008-09-04 | Chinese medicament for treating acute and chronic mammary hyperplasia and preparation method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101664533B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102908603B (en) * | 2012-10-30 | 2014-06-18 | 王凤 | Chinese medicament for treating hyperplasia of mammary glands |
CN107007772A (en) * | 2017-05-15 | 2017-08-04 | 铜仁市凯盛水产养殖有限公司 | A kind of cold water fish forage Chinese medicine additive and preparation method thereof |
CN107569651A (en) * | 2017-09-13 | 2018-01-12 | 李晓艳 | A kind of emplastrum for treating proliferation of mammary gland mastitis |
CN115887565A (en) * | 2023-01-06 | 2023-04-04 | 河南比福制药股份有限公司 | Radix linderae decoction for liver depression and qi stagnation and preparation method and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1857670A (en) * | 2006-03-21 | 2006-11-08 | 吉林省中医中药研究院 | Medicine for treating hyperplasia of mammary glands and its preparing method |
-
2008
- 2008-09-04 CN CN 200810051138 patent/CN101664533B/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1857670A (en) * | 2006-03-21 | 2006-11-08 | 吉林省中医中药研究院 | Medicine for treating hyperplasia of mammary glands and its preparing method |
Non-Patent Citations (2)
Title |
---|
张凤仙等.中西医结合治疗乳腺增生病的研究进展.《云南中医中药杂志》.2007,第28卷(第1期),第43-45页. * |
秦元刚等.乳腺增生病的中医药治疗研究.《中原医刊》.2005,第32卷(第24期),第43、44页. * |
Also Published As
Publication number | Publication date |
---|---|
CN101664533A (en) | 2010-03-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2009062338A1 (en) | A lactogenic chinese medicine for treatment and prevention of gynecopathy, methods of preparation and uses thereof | |
CN104162094B (en) | A kind of Chinese medicine composition and its pharmaceutical preparation for treating Obesity-type Polycystic Ovary Syndrome | |
CN103830577B (en) | A kind of medical composition and its use treating hepatobiliary calculus and urinary stone disease | |
CN101664533B (en) | Chinese medicament for treating acute and chronic mammary hyperplasia and preparation method | |
CN101007151A (en) | Traditional Chinese medicine and its preparation for treating chronic nephritis | |
CN101129971B (en) | Traditional Chinese medicine composition for treating women's menorrhalgia and menoxenia, and method of preparing the same | |
CN102526342B (en) | Traditional Chinese medicine preparation for treating chronic cervicitis | |
CN101664541B (en) | Medicament for treating dysmenorrhoea and preparation method thereof | |
CN101342249B (en) | Chinese medicine formulations for treating hepatitis B and preparation method thereof | |
CN103212054A (en) | Chinese medicine composition for treating infertility of women and preparation method thereof | |
CN110368445A (en) | A kind of Chinese medicine composition and its preparation method and application for treating psoriasis | |
CN113599475B (en) | Middle-warming and kidney-tonifying composition for treating polycystic ovarian syndrome and preparation method and application thereof | |
CN106390035A (en) | Traditional Chinese medicine preparation for treating mammary gland hyperplasia | |
CN101564483B (en) | Liver smoothing for treating hyperplasia of mammary glands | |
CN104547789A (en) | Traditional Chinese medicine for treating qi and blood deficiency type postpartum hypogalactia and preparation method thereof | |
CN104587316B (en) | Anti-gout composition and its preparation method and application | |
CN104147268B (en) | Traditional Chinese medicine composition and preparation thereof for treating hepatic and gallbladder calculus | |
CN107213426A (en) | Treat Chinese patent drug of mammary gland disease and preparation method thereof | |
CN105853796A (en) | Medicine composition for treating habitual abortion | |
CN106540168B (en) | Traditional Chinese medicine composition for treating kidney deficiency type irregular menstruation, amenorrhea and infertility as well as preparation method and application thereof | |
CN104645245B (en) | A kind of preparation method for Menopause depression pharmaceutical preparation | |
CN101670067A (en) | Medicament for treating endometriosis and preparation process thereof | |
CN102038771B (en) | Application of discolor cinquefoil herb in preparation of medicines for treating hysteromyoma | |
CN112494560A (en) | Preparation process of Chinese patent medicine for treating prostate disease | |
CN102309683B (en) | Application of traditional Chinese medicinal composition in preparing medicines for treating hysteromyoma |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: JILIN MODERN CHINESE MEDICINE ENGINEERING RESEARCH Free format text: FORMER OWNER: LI YANHUA Effective date: 20131010 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20131010 Address after: 130012 No. 2426 Qianjin Street, Changchun hi tech Development Zone, Jilin, China Patentee after: Jilin Modern Chinese Medicine Engineering Research Center Co., Ltd. Address before: 130012 No. 2426 Qianjin Street, Changchun hi tech Development Zone, Jilin, China Patentee before: Li Yanhua |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20181119 Address after: No. 39, Modified Road, Tonghua City, Jilin Province, 134000 Patentee after: Tongyao Pharmaceutical Group Corporation Address before: 130012 No. 2426 Qianjin Street, Changchun hi tech Development Zone, Jilin, China Patentee before: Jilin Modern Chinese Medicine Engineering Research Center Co., Ltd. |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A traditional Chinese medicine for treating acute and chronic hyperplasia of mammary glands and its preparation method Effective date of registration: 20201126 Granted publication date: 20130403 Pledgee: Tonghua Branch of China Everbright Bank Co.,Ltd. Pledgor: Tongyao Pharmaceutical Group Corp. Registration number: Y2020220000086 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20211221 Granted publication date: 20130403 Pledgee: Tonghua Branch of China Everbright Bank Co.,Ltd. Pledgor: Tongyao Pharmaceutical Group Corp. Registration number: Y2020220000086 |