CN101637607A - Dragon and tiger rentan plant medicine composition, preparation method and application thereof - Google Patents

Dragon and tiger rentan plant medicine composition, preparation method and application thereof Download PDF

Info

Publication number
CN101637607A
CN101637607A CN200910194559A CN200910194559A CN101637607A CN 101637607 A CN101637607 A CN 101637607A CN 200910194559 A CN200910194559 A CN 200910194559A CN 200910194559 A CN200910194559 A CN 200910194559A CN 101637607 A CN101637607 A CN 101637607A
Authority
CN
China
Prior art keywords
preparation
powder
tiger
dragon
rentan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN200910194559A
Other languages
Chinese (zh)
Other versions
CN101637607B (en
Inventor
滕洪铭
李能贵
王毓
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Zhonghua Pharmaceutical CO Ltd
Original Assignee
Shanghai Zhonghua Pharmaceutical CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Zhonghua Pharmaceutical CO Ltd filed Critical Shanghai Zhonghua Pharmaceutical CO Ltd
Priority to CN2009101945591A priority Critical patent/CN101637607B/en
Publication of CN101637607A publication Critical patent/CN101637607A/en
Application granted granted Critical
Publication of CN101637607B publication Critical patent/CN101637607B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a dragon and tiger rentan plant medicine composition, a preparation method and application thereof. The dragon and tiger rentan plant medicine composition comprises the following active components by weight proportions: 32-48g of menthol, 24-36g of borneol, 20-30g of cloves, 20-30g of villous amomum, 12-18g of star aniseeds, 32-48g of cinnamon, 12-18g of pepper, 12-18g ofcostus roots, 20-30g of dried ginger, 160-240g of catechu, 291.28-436.92g of glycyrrhiza, and the like. The preparation method comprises the following steps: preparing catechu pulp; and adding the mixed powder to prepare pills. The invention has short preparation period, low cost and good quality; and the dragon and tiger rentan plant medicine composition is used for preventing or treating heat stroke dizziness, nausea and vomiting, diarrhea, train and ship sickness, and the like.

Description

A kind of dragon and tiger rentan plant medicine composition and preparation and application
Technical field
The invention belongs to plant amedica compositions and preparation thereof and application, particularly relate to a kind of dragon and tiger rentan plant medicine composition and preparation and application.
Background technology
The dragon and tiger RENDAN has refreshment, sunstroke prevention antidiarrheal, treat effects such as seasick carsickness, as far back as 1911, when Shanghai China drugmaker sets up, just research and development form according to ancient prescription " Zhuge's March Powder ", and its pill is mainly starched by glutinous rice flour by Mentholum, Borneolum Syntheticum, catechu, Radix Glycyrrhizae etc., and drying, polishing are made.
Put down in writing according to Compendium of Material Medica: " Mentholum " acrid in the mouth is cool in nature; Dispelling wind, heat clearing away, main air hotness are emitted, headache, conjunctival congestion, laryngopharynx swelling and pain, toothache, skin pruritus." Borneolum Syntheticum " is hot, bitter, is slightly cold; Have one's ideas straightened out refreshment, clearing away heat to alleviate pain; Be used for the calentura coma, convulsion is fainted, the apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated." Flos Caryophylli " suffering, temperature; Warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.Be used for Deficiency and coldness of spleen and stomach, singultus vomiting, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney." Fructus Amomi " acrid in the mouth, temperature; The removing dampness circulation of qi promoting, warming spleen and stopping diarrha, antiabortive.It is vexed to be used for breast gastral cavity painful abdominal mass, abdominal distention and little diet, and stomachache is had loose bowels, frequent fetal movement, pregnancy reactions." Fructus Anisi Stellati " suffering, temperature; Warming YANG to expel cold, regulating QI to relieve pain.Be used for colic of cold type stomachache, lumbago due to renal deficiency, gastrofrigid vomiting, coldness and pain in the epigastrium." Cortex Cinnamomi " is hot, sweet, big heat; It is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily, dizziness due to yang deficiency, the conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea." Fructus Piperis " suffering, heat; Warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.Be used for gastrofrigid vomiting, stomachache is had loose bowels, inappetence, epilepsy abundant expectoration." Radix Aucklandiae " is warm in nature, acrid in the mouth, hardship; Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for heavy behind breast gastral cavity distending pain, the dysentery, food stagnation does not disappear, anorexia." Rhizoma Zingiberis " suffering, heat; Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention." catechu " bitter in the mouth, puckery, cool; Invigorate blood circulation and cure the wound, hemostasia and promoting granulation is held back skin ulcer.Be used for the wound congestive edema, hemorrhage, eczema, cough due to lung-heat." Radix Glycyrrhizae " is sweet, and be flat; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Especially modern rhythm along with work and life is accelerated, and increasing people is nervous and tired, in office, the long-time nervous working and learning in classroom, very easily cause brain fag, have a strong impact on work, study and sleep, even tired contingency occurs.Therefore the market sales volume of dragon and tiger RENDAN enlarges day by day, presents ascendant trend year by year, is just producing very positive social benefit and economic benefit.Many description and documents about dragon and tiger RENDAN prescription were arranged in the past, but only relate to part plant amedica wherein, still unexposed up to now complete prescription, the preparation of dragon and tiger RENDAN is by the research and development of last 100 years simultaneously, operate to semi-hand by full manual operations, realize full mechanization production until in recent years, also do not see the pertinent literature report.
Summary of the invention
Technical problem to be solved by this invention provides a kind of dragon and tiger rentan plant medicine composition and preparation and application, and the present invention has refreshment, and sunstroke prevention antidiarrheal is treated effects such as seasick carsickness; And with short production cycle, cost is low, and quality is good.
A kind of dragon and tiger rentan plant medicine composition of the present invention comprises the active component of following mass parts:
Per 1000 grams include:
Mentholum 32~48g
Borneolum Syntheticum 24~36g
Flos Caryophylli 20~30g
Fructus Amomi 20~30g
Fructus Anisi Stellati 12~18g
Cortex Cinnamomi 32~48g
Fructus Piperis 12~18g
The Radix Aucklandiae 12~18g
Rhizoma Zingiberis 20~30g
Catechu 160~240g
Radix Glycyrrhizae 291.28~436.92g
Glutinous rice flour 144~216g
Sodium benzoate 4~6g
Red ferric oxide 11.6~17.4g
Simethicone 0.08~0.12ml
Graphite 0.16~0.24g
Pulvis Talci 0.16~0.24g
Dextrin 3.16~4.74g.
Described dragon and tiger rentan plant medicine compositions, be to be applied to the patient who needs this treatment by oral mode, consumption is according to the type and the order of severity adjustment of patient's age, body weight, the disease of being treated, and its, dosage was 0.48g-0.96g every day, and one or many is used.
Described dragon and tiger rentan plant medicine compositions preparation can be made into solid preparation such as tablet, powder, granule, pill, capsule, and tablet is slow releasing tablet or coated tablet.
The preparation method of a kind of dragon and tiger rentan plant medicine composition of the present invention comprises:
(1) preparation of soft material
A. the preparation of catechu slurry: according to above-mentioned mass parts catechu is mixed stirring with purified water by mass ratio at 1: 1, control steam pressure 0.25~0.5Mpa, 60~95 ℃ of temperature are heated to dissolving, filter catechu solution; With 5~18% of sodium benzoate, catechu solution and above-mentioned glutinous rice flour amount, stirred 3~5 minutes then in batches, pulled an oar discharging 10~30 minutes;
B. the preparation of mixed powder: get above-mentioned mass parts glutinous rice flour, amomum powder, Fructus Anisi Stellati powder, Cortex Cinnamomi powder, Fructus Piperis powder, Radix Aucklandiae powder, ginger powder, Flos Caryophylli powder and Radix Glycyrrhizae powder mixed material feeding, spray in advance through melting filtering volatility raw material, mix while spraying, after hydrojet finishes, discharging;
C. with above-mentioned mixed powder, catechu slurry, mix and stirred 15~30 minutes, discharging gets final product;
(2) preparation of pill
A. soft material is made rounding, wet hair ball of uniform size;
B. the wet hair ball is drawn light, add dextrin solution and stir evenly, blowing is sprinkled into red ferric oxide after being rolled into surface-brightening, splashes into simethicone again, and the coating time was at 0.5~2.5 hour;
C. dry sterilization is selected the pill of ball footpath between 4.0mm~4.5mm, adds graphite powder and Pulvis Talci polishing.
The glutinous rice flour among described step (1) a and the mass ratio of catechu solution are 1: 1~20: 1.
Volatility raw material in the described step (1) is Mentholum and Borneolum Syntheticum.
Dextrin solution in the described step (2) is the mixed liquor of 1: 1 dextrin of mass ratio and purified water.
Dry sterilization in the described step (2) carries out dry sterilization, several 1~50 of microwave tube, thickness 0.02~2.5mm, belt speed 0.5~3m/min for adopting microwave generator.
A kind of dragon and tiger rentan plant medicine composition of the present invention is dizzy in preparation prevention or treatment heatstroke, nausea and vomiting, the application in diarrhoea and the carsick seasick relevant medicine.
The present invention as adhesive and wetting agent, adopts wet ball coating to can further improve the roundness of pill with white dextrin, can reduce the adhesion of pill simultaneously, improves qualification rate, the yield rate of pill; Simultaneously, the adding of iron oxide red can with the hygroscopicity of minimizing pill in storage period, also can reduce the loss of volatile oil in storage period at the tight iron oxide layer of pill surface coverage one deck; Graphite powder, Pulvis Talci can make pill have special gloss, can increase the lubricity of pill simultaneously, are convenient to adopt mechanical packaging.Preparation method of the present invention adopts microwave drying sterilization to replace the far infrared sterilizing installation, time only needs 20min~30min, it is long to have shortened drying time greatly, adopts spiral horizontal propulsive pellet processing machine simultaneously, and shaping casement plate is bigger by 1/3 than traditional pellet processing machine template, on 8 holes are arranged, the pill surface ratio of producing is than rounding, and the speed of a motor vehicle is accelerated more obvious, does not see two grain, gong and drum shapes, little tail, many, the ball etc. of blooming are arranged, qualified yield rate is reached more than 90%, and output is about 40~47kg/ hour.
Effect of the present invention is remarkable, carry take very convenient.The production cycle of this pill only needs 4 days, and cost is low, has adopted microwave drying sterilization technology and spiral horizontal propelling pellet processing machine, has improved the content of effective of product, has guaranteed the quality of product.
The specific embodiment
Below in conjunction with specific embodiment, further set forth the present invention.Should be understood that these embodiment only to be used to the present invention is described and be not used in and limit the scope of the invention.Should be understood that in addition those skilled in the art can make various changes or modifications the present invention after the content of having read the present invention's instruction, these equivalent form of values fall within the application's appended claims institute restricted portion equally.
Embodiment 1
Prescription: per 1000 grams include,
Mentholum 32g
Borneolum Syntheticum 24g
Flos Caryophylli 20g
Fructus Amomi 20g
Fructus Anisi Stellati 12g
Cortex Cinnamomi 32g
Fructus Piperis 12g
Radix Aucklandiae 12g
Rhizoma Zingiberis 20g
Catechu 160g
Radix Glycyrrhizae 291.28g
Glutinous rice flour 144g
Sodium benzoate 4g
Red ferric oxide 11.6g
Simethicone 0.08ml
Graphite 0.16g
Pulvis Talci 0.16g
Dextrin 3.16g.
Embodiment 2
Prescription: per 1000 grams include,
Mentholum 40g
Borneolum Syntheticum 30g
Flos Caryophylli 25g
Fructus Amomi 25g
Fructus Anisi Stellati 15g
Cortex Cinnamomi 40g
Fructus Piperis 15g
Radix Aucklandiae 15g
Rhizoma Zingiberis 25g
Catechu 200g
Radix Glycyrrhizae 364.1g
Glutinous rice flour 180g
Sodium benzoate 5g
Red ferric oxide 14.5g
Simethicone 0.1ml
Graphite 0.2g
Pulvis Talci 0.2g
Dextrin 3.95g.
Embodiment 3
Prescription: per 1000 grams include,
Mentholum 48g
Borneolum Syntheticum 36g
Flos Caryophylli 30g
Fructus Amomi 30g
Fructus Anisi Stellati 18g
Cortex Cinnamomi 48g
Fructus Piperis 18g
Radix Aucklandiae 18g
Rhizoma Zingiberis 30g
Catechu 240g
Radix Glycyrrhizae 436.92g
Glutinous rice flour 216g
Sodium benzoate 6g
Red ferric oxide 17.4g
Simethicone 0.12ml
Graphite 0.24g
Pulvis Talci 0.24g
Dextrin 4.74g.
Embodiment 4
Preparation method:
(1) catechu dissolving: taking by weighing catechu, will be that 1: 1 purified water is put into dissolving pan with the catechu mass ratio, open and stir, and drop into catechu, open spacer steam, steam pressure 0.25Mpa, and 60 ℃ of temperature controls are heated to dissolving, filter;
(2) catechu slurry preparation: take by weighing glutinous rice flour (recipe quantity 5%) consumption, sodium benzoate and catechu solution, the mass ratio of glutinous rice flour and catechu solution 1: 1, dropping into blender respectively stirred 3~5 minutes, and then unlatching steam valve, steam pressure 0.25Mpa, pulled an oar steam off valve and blender, discharging 10 minutes;
(3) fusion of volatility raw material: take by weighing Mentholum, Borneolum Syntheticum, drop into respectively in the fusion pot, fusing is filtered;
(4) mix: take by weighing glutinous rice flour, amomum powder, Fructus Anisi Stellati powder, Cortex Cinnamomi powder, Fructus Piperis powder, Radix Aucklandiae powder, ginger powder, Flos Caryophylli powder, Radix Glycyrrhizae powder, drop into and mix the mixing of powder machine, spray into filtered volatility raw material, mix while spraying, after hydrojet finishes, discharging;
(5) system soft material: take by weighing mixed powder, catechu slurry, drop into respectively in the blender, open blender, stirred 15~30 minutes, close blender, discharging;
(6) pill: open pellet processing machine and cooling water, then with soft material, drop into pellet processing machine and carry out pill, the pill of molding falls within on the conveyer belt, the pill shall be rounded up of making, and size is evenly;
(7) preparation of dextrin solution: take by weighing dextrin, add in the dissolving tank, add a small amount of purified water, stir and make swelling, add boiling water again, the limit trimming stirs, and dextrin and water ratio are 1: 1;
(8) coating: take by weighing wet hair ball (about 35~70 kilograms every pot), pour in the operating coating pan, draw light, add dextrin solution and stir evenly in right amount, blowing is sprinkled into red ferric oxide after being rolled into surface-brightening, splash into simethicone, make coated pill glossy, single pan coating time was controlled at 0.5~2.5 hour;
(9) dry sterilization: open the microwave drying sterilization machine, with parameter setting be: belt speed: 0.5m/min, thickness: 0.02~1.0mm, the microwave tube number: 5, coated pill is sent into the microwave drying sterilization machine, after the pill drying, select and choose ball;
(10) ball is chosen in choosing: pill is by selecting the ball machine, big screen distance :=4.5mm, and little screen distance: φ=4.0mm rejects defective pill;
(11) polishing: take by weighing dried dried light ball, drop in the coating pan, add graphite powder and Pulvis Talci, polishing is finished product after the packing.
Embodiment 5
Preparation method:
(1) catechu dissolving: taking by weighing catechu, will be that 1: 1 purified water is put into dissolving pan with the catechu mass ratio, open and stir, and drop into catechu, open spacer steam, steam pressure 0.3Mpa, and 85 ℃ of temperature controls are heated to dissolving, filter;
(2) catechu slurry preparation: take by weighing glutinous rice flour (recipe quantity 10%) consumption, sodium benzoate and catechu solution, the mass ratio of glutinous rice flour and catechu solution 10: 1, dropping into blender respectively stirred 3~5 minutes, and then unlatching steam valve, steam pressure 0.3Mpa, pulled an oar steam off valve and blender, discharging 10~30 minutes;
(3) fusion of volatility raw material: take by weighing Mentholum, Borneolum Syntheticum, drop into respectively in the fusion pot, fusing is filtered;
(4) mix: take by weighing glutinous rice flour, amomum powder, Fructus Anisi Stellati powder, Cortex Cinnamomi powder, Fructus Piperis powder, Radix Aucklandiae powder, ginger powder, Flos Caryophylli powder, Radix Glycyrrhizae powder, drop into and mix the mixing of powder machine, spray into filtered volatility raw material, mix while spraying, after hydrojet finishes, discharging;
(5) system soft material: take by weighing mixed powder, catechu slurry, drop into respectively in the blender, open blender, stirred 15~30 minutes, close blender, discharging;
(6) pill: open pellet processing machine and cooling water, then with soft material, drop into pellet processing machine and carry out pill, the pill of molding falls within on the conveyer belt, the pill shall be rounded up of making, and size is evenly;
(7) preparation of dextrin solution: take by weighing dextrin, add in the dissolving tank, add a small amount of purified water, stir and make swelling, add boiling water again, the limit trimming stirs, and dextrin and water ratio are 1: 1;
(8) coating: take by weighing wet hair ball (about 35~70 kilograms every pot), pour in the operating coating pan, draw light, add dextrin solution and stir evenly in right amount, blowing is sprinkled into red ferric oxide after being rolled into surface-brightening, splash into simethicone, make coated pill glossy, single pan coating time was controlled in 2.5 hours;
(9) dry sterilization: open the microwave drying sterilization machine, with parameter setting be: belt speed: 0.8m/min, thickness: 1.0~1.5mm, the microwave tube number: 30, coated pill is sent into the microwave drying sterilization machine, after the pill drying, select and choose ball;
(10) ball is chosen in choosing: pill is by selecting the ball machine, big screen distance: φ=4.5mm, and little screen distance: φ=4.0mm rejects defective pill;
(11) polishing: take by weighing dried dried light ball, drop in the coating pan, add graphite powder and Pulvis Talci, polishing is finished product after the packing.
Embodiment 6
Preparation method:
(1) catechu dissolving: taking by weighing catechu, will be that 1: 1 purified water is put into dissolving pan with the catechu mass ratio, open and stir, and drop into catechu, open spacer steam, steam pressure 0.5Mpa, and 95 ℃ of temperature controls are heated to dissolving, filter;
(2) catechu slurry preparation: take by weighing glutinous rice flour (recipe quantity 18%) consumption, sodium benzoate and catechu solution, the mass ratio of glutinous rice flour and catechu solution 20: 1, dropping into blender respectively stirred 3~5 minutes, and then unlatching steam valve, steam pressure 0.5Mpa, pulled an oar steam off valve and blender, discharging 10~30 minutes;
(3) fusion of volatility raw material: take by weighing Mentholum, Borneolum Syntheticum, drop into respectively in the fusion pot, fusing is filtered;
(4) mix: take by weighing glutinous rice flour, amomum powder, Fructus Anisi Stellati powder, Cortex Cinnamomi powder, Fructus Piperis powder, Radix Aucklandiae powder, ginger powder, Flos Caryophylli powder, Radix Glycyrrhizae powder, drop into and mix the mixing of powder machine, spray into filtered volatility raw material, mix while spraying, after hydrojet finishes, discharging;
(5) system soft material: take by weighing mixed powder, catechu slurry, drop into respectively in the blender, open blender, stirred 15~30 minutes, close blender, discharging;
(6) pill: open pellet processing machine and cooling water, then with soft material, drop into pellet processing machine and carry out pill, the pill of molding falls within on the conveyer belt, the pill shall be rounded up of making, and size is evenly;
(7) preparation of dextrin solution: take by weighing dextrin, add in the dissolving tank, add a small amount of purified water, stir and make swelling, add boiling water again, the limit trimming stirs, and dextrin and water ratio are 1: 1;
(8) coating: take by weighing wet hair ball (about 35~70 kilograms every pot), pour in the operating coating pan, draw light, adding dextrin solution stirs evenly in right amount, blowing is sprinkled into red ferric oxide after being rolled into surface-brightening, splashes into simethicone, make coated pill glossy, single pan coating time was controlled in 0.5~2.5 hour;
(9) dry sterilization: open the microwave drying sterilization machine, with parameter setting be: belt speed: 3m/min, thickness: 1.5~2.5mm, the microwave tube number: 50, coated pill is sent into the microwave drying sterilization machine, after the pill drying, select and choose ball;
(10) ball is chosen in choosing: pill is by selecting the ball machine, big screen distance: φ=4.5mm, and little screen distance: φ=4.0mm rejects defective pill;
(11) polishing: take by weighing dried dried light ball, drop in the coating pan, add graphite powder and Pulvis Talci, polishing is finished product after the packing.

Claims (10)

1. dragon and tiger rentan plant medicine composition comprises the active component of following mass parts:
Per 1000 grams include:
Mentholum 32~48g
Borneolum Syntheticum 24~36g
Flos Caryophylli 20~30g
Fructus Amomi 20~30g
Fructus Anisi Stellati 12~18g
Cortex Cinnamomi 32~48g
Fructus Piperis 12~18g
The Radix Aucklandiae 12~18g
Rhizoma Zingiberis 20~30g
Catechu 160~240g
Radix Glycyrrhizae 291.28~436.92g
Glutinous rice flour 144~216g
Sodium benzoate 4~6g
Red ferric oxide 11.6~17.4g
Simethicone 0.08~0.12ml
Graphite 0.16~0.24g
Pulvis Talci 0.16~0.24g
Dextrin 3.16~4.74g.
2. a kind of dragon and tiger rentan plant medicine composition as claimed in claim 1, it is characterized in that being applied to the patient of this treatment of needs by oral mode, consumption is according to the type and the order of severity adjustment of patient's age, body weight, the disease of being treated, its, dosage was 0.48g-0.96g every day, and one or many is used.
3. a kind of dragon and tiger rentan plant medicine composition as claimed in claim 1 is characterized in that preparation can be made into solid preparation such as tablet, powder, granule, pill, capsule.
4. a kind of dragon and tiger rentan plant medicine composition as claimed in claim 3 is characterized in that tablet is slow releasing tablet or coated tablet.
5. the preparation method of a dragon and tiger rentan plant medicine composition comprises:
(1) preparation of soft material
A. the preparation of catechu slurry: according to above-mentioned mass parts catechu is mixed stirring with purified water by mass ratio at 1: 1, control steam pressure 0.25~0.5Mpa, 60~95 ℃ of temperature are heated to dissolving, filter catechu solution; With 5~18% of sodium benzoate, catechu solution and above-mentioned glutinous rice flour amount, stirred 3~5 minutes then in batches, pulled an oar discharging 10~30 minutes;
B. the preparation of mixed powder: get above-mentioned mass parts glutinous rice flour, amomum powder, Fructus Anisi Stellati powder, Cortex Cinnamomi powder, Fructus Piperis powder, Radix Aucklandiae powder, ginger powder, Flos Caryophylli powder and Radix Glycyrrhizae powder mixed material feeding, spray in advance through melting filtering volatility raw material, mix while spraying, after hydrojet finishes, discharging;
C. with above-mentioned mixed powder, catechu slurry, mix and stirred 15~30 minutes, discharging gets final product;
(2) preparation of pill
A. soft material is made rounding, wet hair ball of uniform size;
B. the wet hair ball is drawn light, add dextrin solution and stir evenly, blowing is sprinkled into red ferric oxide after being rolled into surface-brightening, splashes into simethicone again, and the coating time was at 0.5~2.5 hour;
C. dry sterilization is selected the pill of ball footpath between 4.0mm~4.5mm, adds graphite powder and Pulvis Talci polishing.
6. the preparation method of a kind of dragon and tiger rentan plant medicine composition as claimed in claim 5 is characterized in that: the glutinous rice flour among described step (1) a and the mass ratio of catechu solution are 1: 1~20: 1.
7. the preparation method of a kind of dragon and tiger rentan plant medicine composition as claimed in claim 5 is characterized in that: the volatility raw material in the described step (1) is Mentholum and Borneolum Syntheticum.
8. the preparation method of a kind of dragon and tiger rentan plant medicine composition as claimed in claim 5 is characterized in that: the dextrin solution in the described step (2) is the mixed liquor of 1: 1 dextrin of mass ratio and purified water.
9. the preparation method of a kind of dragon and tiger rentan plant medicine composition as claimed in claim 5, it is characterized in that: the dry sterilization in the described step (2) carries out dry sterilization for adopting microwave generator, several 1~50 of microwave tube, thickness 0.02~2.5mm, belt speed 0.5~3m/min.
10. a dragon and tiger rentan plant medicine composition is dizzy in preparation prevention or treatment heatstroke, nausea and vomiting, the application in diarrhoea and the carsick seasick relevant medicine.
CN2009101945591A 2009-08-25 2009-08-25 Dragon and tiger rentan plant medicine composition, preparation method and application thereof Active CN101637607B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009101945591A CN101637607B (en) 2009-08-25 2009-08-25 Dragon and tiger rentan plant medicine composition, preparation method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009101945591A CN101637607B (en) 2009-08-25 2009-08-25 Dragon and tiger rentan plant medicine composition, preparation method and application thereof

Publications (2)

Publication Number Publication Date
CN101637607A true CN101637607A (en) 2010-02-03
CN101637607B CN101637607B (en) 2012-02-15

Family

ID=41612909

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009101945591A Active CN101637607B (en) 2009-08-25 2009-08-25 Dragon and tiger rentan plant medicine composition, preparation method and application thereof

Country Status (1)

Country Link
CN (1) CN101637607B (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102309550A (en) * 2010-07-06 2012-01-11 中国人民解放军第三○二医院 Traditional Chinese medicinal aerosol for preventing and treating summer humidity disease and preparation method thereof
CN104623601A (en) * 2015-02-04 2015-05-20 北京全净通一科技有限公司 Pain relieving oil agent for external use and preparation method of pain relieving oil agent
CN104931592A (en) * 2014-03-19 2015-09-23 上海中华药业有限公司 Content detection method of 14 non-volatile components in dragon tiger Rendan mini-pill vegetable drug
CN104950045A (en) * 2014-03-27 2015-09-30 上海中华药业有限公司 Detection method for contents of six volatile components in vegetable drugs of Longhurendan
CN106692936A (en) * 2017-02-09 2017-05-24 东莞市辛济生物科技有限公司 Carsick patch
CN107233542A (en) * 2017-05-02 2017-10-10 上海中华药业有限公司 Application of the dragon and tiger jintan in prevention and/or treatment hepatic fibrosis medicines is prepared
CN107261079A (en) * 2017-05-02 2017-10-20 上海中华药业有限公司 Application of the dragon and tiger jintan in prevention and/or treatment diabetes medicament is prepared
CN108421017A (en) * 2018-05-09 2018-08-21 上海中华药业有限公司 Application of the dragon and tiger jintan in preparing reducing blood lipid and artery plaque drug
CN109512995A (en) * 2019-01-17 2019-03-26 上海中华药业有限公司 A kind of antitumor Chinese and its extractive of volatile oil
CN109529005A (en) * 2019-01-17 2019-03-29 上海中华药业有限公司 Jintan is used to treat the new application that ras proto-oncogene is overexpressed tumour
CN109620942A (en) * 2019-01-17 2019-04-16 上海中华药业有限公司 Application of the jintan in preparation prevention or treatment Huntington chorea disease drug
CN112316100A (en) * 2020-12-07 2021-02-05 上海中华药业有限公司 New use of HUDAN Chinese medicinal composition for preventing and relieving hangover or treating alcoholic liver injury

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102309550A (en) * 2010-07-06 2012-01-11 中国人民解放军第三○二医院 Traditional Chinese medicinal aerosol for preventing and treating summer humidity disease and preparation method thereof
CN104931592A (en) * 2014-03-19 2015-09-23 上海中华药业有限公司 Content detection method of 14 non-volatile components in dragon tiger Rendan mini-pill vegetable drug
CN104950045A (en) * 2014-03-27 2015-09-30 上海中华药业有限公司 Detection method for contents of six volatile components in vegetable drugs of Longhurendan
CN104623601B (en) * 2015-02-04 2018-02-13 北京全净通一科技有限公司 A kind of exterior-applied antalgic finish and preparation method
CN104623601A (en) * 2015-02-04 2015-05-20 北京全净通一科技有限公司 Pain relieving oil agent for external use and preparation method of pain relieving oil agent
CN106692936A (en) * 2017-02-09 2017-05-24 东莞市辛济生物科技有限公司 Carsick patch
CN107233542B (en) * 2017-05-02 2021-01-26 上海中华药业有限公司 Application of longhurendan in preparing medicine for preventing and/or treating hepatic fibrosis
CN107233542A (en) * 2017-05-02 2017-10-10 上海中华药业有限公司 Application of the dragon and tiger jintan in prevention and/or treatment hepatic fibrosis medicines is prepared
WO2018201920A1 (en) * 2017-05-02 2018-11-08 上海中华药业有限公司 Use of dragon tiger panacea in preparation of drug for preventing and/or treating hepatic fibrosis
CN107261079A (en) * 2017-05-02 2017-10-20 上海中华药业有限公司 Application of the dragon and tiger jintan in prevention and/or treatment diabetes medicament is prepared
US11793852B2 (en) * 2017-05-02 2023-10-24 Shanghai Zhonghua Pharmaceutical Co., Ltd Application of Longhu Rendan in preparing medicament for preventing and/or treating liver fibrosis
US20210038675A1 (en) * 2017-05-02 2021-02-11 Shanghai Zhonghua Pharmaceutical Co., Ltd Application of longhu rendan in preparing medicament for preventing and/or treating liver fibrosis
US20190275100A1 (en) * 2017-05-02 2019-09-12 Shanghai Zhonghua Pharmaceutical Co., Ltd Application of longhu rendan in preparing medicament for preventing and/or treating liver fibrosis
CN107261079B (en) * 2017-05-02 2021-01-26 上海中华药业有限公司 Application of longhurendan in preparation of medicine for preventing and/or treating diabetes
CN108421017A (en) * 2018-05-09 2018-08-21 上海中华药业有限公司 Application of the dragon and tiger jintan in preparing reducing blood lipid and artery plaque drug
CN109512995A (en) * 2019-01-17 2019-03-26 上海中华药业有限公司 A kind of antitumor Chinese and its extractive of volatile oil
CN109620942A (en) * 2019-01-17 2019-04-16 上海中华药业有限公司 Application of the jintan in preparation prevention or treatment Huntington chorea disease drug
CN109529005B (en) * 2019-01-17 2021-12-10 上海中华药业有限公司 New use of human pill for treating ras proto-oncogene overexpression tumor
CN109529005A (en) * 2019-01-17 2019-03-29 上海中华药业有限公司 Jintan is used to treat the new application that ras proto-oncogene is overexpressed tumour
CN112316100A (en) * 2020-12-07 2021-02-05 上海中华药业有限公司 New use of HUDAN Chinese medicinal composition for preventing and relieving hangover or treating alcoholic liver injury
CN112316100B (en) * 2020-12-07 2023-10-03 上海中华药业有限公司 New use of Rendan traditional Chinese medicine composition for preventing drunk and dispelling effects of alcohol or treating alcoholic liver injury

Also Published As

Publication number Publication date
CN101637607B (en) 2012-02-15

Similar Documents

Publication Publication Date Title
CN101637607B (en) Dragon and tiger rentan plant medicine composition, preparation method and application thereof
CN1095952A (en) A kind of production method of medicated tea
CN102106991A (en) Medicament for treating moderate/advanced liver cancer chemoembolization
CN103816428B (en) A kind of preparation of effective treatment diabetes
CN107349411A (en) Chinese medicine composition for treating irregular menstruation and preparation method thereof
CN100522222C (en) Plaster for treating cough in children
CN101461907B (en) Medicament for treating liver-yang hyperactivity, extinguishing liver-wind and nourishing kidney-yin as well as preparation method
CN102366527A (en) Traditional Chinese medicine formula for treating vitiligo
CN102258718A (en) Integrated alcoholic beverage and preparation method as well as application thereof
CN102961621A (en) Traditional Chinese medicine preparation for treating viral cardiac neurosis
CN107261043A (en) Chinese medicine composition for nursing one's health the human body deficiency of yang and preparation method thereof
CN108272958A (en) It is a kind of to have effects that improve the composition of male sexual
CN102335350A (en) Oral Chinese medicinal preparation for treating epilepsy
CN106665970A (en) Tomato and green tea herbal cuisine composite and preparation method thereof
CN108578554A (en) A kind of spraying agent for ulcer of oral cavity and preparation method thereof
CN110420309B (en) Anti-inflammatory analgesic Tibetan medicine pill for treating chronic appendicitis
CN108743771A (en) A kind of Fuke Tiaojing tablets and its preparation process
CN106616373A (en) Black soybean powder with effect of tonifying the kidney and spleen and preparation method of black soybean powder
CN1064532C (en) Pill for pelvic inflammation and cervical erosion
CN101229343B (en) Chinese traditional medicine for treating pulmonary tuberculosis
CN114949096A (en) Preparation method of tablet for relaxing muscles and tendons and promoting blood circulation
CN102335306A (en) Oral Chinese medicinal composition for treating epilepsia
CN103055269A (en) Chinese medicinal herb preparation for treating hysteria
CN104758731A (en) Traditional Chinese medicine compound for treating lip anabrosis
CN114288348A (en) Deer penis, deer blood and ginseng edible pill capable of regenerating cells and improving chronic functions of organism

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant