CN101622013A - 包含丁丙诺啡和纳洛酮的改善的药用组合物 - Google Patents

包含丁丙诺啡和纳洛酮的改善的药用组合物 Download PDF

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Publication number
CN101622013A
CN101622013A CN200880006847A CN200880006847A CN101622013A CN 101622013 A CN101622013 A CN 101622013A CN 200880006847 A CN200880006847 A CN 200880006847A CN 200880006847 A CN200880006847 A CN 200880006847A CN 101622013 A CN101622013 A CN 101622013A
Authority
CN
China
Prior art keywords
buprenorphine
naloxone
composition
administration
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880006847A
Other languages
English (en)
Chinese (zh)
Inventor
克利斯托弗·波恩·夏普利奥
尼尔·海德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Reckitt Benckiser Healthcare UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt Benckiser Healthcare UK Ltd filed Critical Reckitt Benckiser Healthcare UK Ltd
Publication of CN101622013A publication Critical patent/CN101622013A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200880006847A 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物 Pending CN101622013A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0703967.0 2007-03-01
GB0703967A GB2447015A (en) 2007-03-01 2007-03-01 Analgesic composition comprising a specific ratio of buprenorphine and naltrexone

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2012101207560A Division CN102670610A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物

Publications (1)

Publication Number Publication Date
CN101622013A true CN101622013A (zh) 2010-01-06

Family

ID=37965734

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880006847A Pending CN101622013A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物
CN2012101207560A Pending CN102670610A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2012101207560A Pending CN102670610A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物

Country Status (16)

Country Link
US (1) US20100168147A1 (enExample)
EP (1) EP2114453A1 (enExample)
JP (1) JP2010520185A (enExample)
KR (1) KR20090115863A (enExample)
CN (2) CN101622013A (enExample)
AR (1) AR065581A1 (enExample)
AU (1) AU2008220573A1 (enExample)
BR (1) BRPI0807905A2 (enExample)
CA (1) CA2678675A1 (enExample)
CL (1) CL2008000610A1 (enExample)
GB (1) GB2447015A (enExample)
MX (1) MX2009009133A (enExample)
PE (1) PE20081874A1 (enExample)
TW (1) TW200836738A (enExample)
WO (1) WO2008104737A1 (enExample)
ZA (1) ZA200905691B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS54764B1 (sr) 2006-07-21 2016-10-31 Biodelivery Sciences Int Inc Sredstvo za transmukozalnu isporuku sa povećanim nakupljanjem
WO2010008863A1 (en) * 2008-06-23 2010-01-21 Biodelivery Sciences International, Inc. Multidirectional mucosal delivery devices and methods of use
US8475832B2 (en) * 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
JP6158810B2 (ja) 2011-08-18 2017-07-05 バイオデリバリー サイエンシズ インターナショナル，インコーポレーテッド ブプレノルフィンの乱用抵抗性粘膜付着性送達デバイス
PT2706986E (pt) 2011-09-19 2015-07-07 Orexo Ab Nova composição farmacêutica resistente ao abuso para o tratamento da dependência de opiáceos
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US20140275148A1 (en) * 2013-03-15 2014-09-18 Novus Pharma LLC Orally administrable, self-supporting dissolving film dosage forms
CA2875384A1 (en) 2013-12-20 2015-06-20 AntiOP, Inc. Intranasal naloxone compositions and methods of making and using same
RU2016136714A (ru) 2014-03-14 2018-04-19 ОПИАНТ ФАРМАСЮТИКАЛС, Инк. Назальные готовые лекарственные формы и способы их применения
US9480644B2 (en) 2014-03-14 2016-11-01 Opiant Pharmaceuticals, Inc. Nasal drug products and methods of their use
US10085937B2 (en) 2014-03-14 2018-10-02 Adapt Pharma Limited Nasal drug products and methods of their use
US9561177B2 (en) 2014-03-14 2017-02-07 Adapt Pharma Limited Nasal drug products and methods of their use
EP4548911A1 (en) 2023-11-06 2025-05-07 Extrovis AG Pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457933A (en) * 1980-01-24 1984-07-03 Bristol-Myers Company Prevention of analgesic abuse
GB8332556D0 (en) * 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions
CN1204890C (zh) * 1997-12-22 2005-06-08 欧罗赛铁克股份有限公司 防止阿片样物质滥用的方法
AR031682A1 (es) * 1999-11-19 2003-10-01 Reckitt Benckiser Helthcare Uk Composiciones farmaceuticas
US20050191340A1 (en) * 2002-08-09 2005-09-01 Gruenenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
ES2290512T3 (es) * 2002-08-09 2008-02-16 Grunenthal Gmbh Antagonistas del receptor opioide en sistemas transdermicos que contienen buprenorfina.
EP1584335A3 (en) * 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Active substance combination comprising a carbinol composition and an opioid
US8236751B2 (en) * 2007-03-07 2012-08-07 The Johns Hopkins University Methods of increasing muscle mass using follistatin-like related gene (FLRG)

Also Published As

Publication number Publication date
GB2447015A (en) 2008-09-03
TW200836738A (en) 2008-09-16
WO2008104737A1 (en) 2008-09-04
US20100168147A1 (en) 2010-07-01
CA2678675A1 (en) 2008-09-04
JP2010520185A (ja) 2010-06-10
AU2008220573A1 (en) 2008-09-04
MX2009009133A (es) 2009-09-03
CL2008000610A1 (es) 2008-09-05
GB0703967D0 (en) 2007-04-11
KR20090115863A (ko) 2009-11-09
CN102670610A (zh) 2012-09-19
PE20081874A1 (es) 2009-01-26
EP2114453A1 (en) 2009-11-11
BRPI0807905A2 (pt) 2014-06-17
ZA200905691B (en) 2010-10-27
AR065581A1 (es) 2009-06-17

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