CN101617673B - Sterilizing composition containing tetraconazole - Google Patents

Sterilizing composition containing tetraconazole Download PDF

Info

Publication number
CN101617673B
CN101617673B CN2009101659068A CN200910165906A CN101617673B CN 101617673 B CN101617673 B CN 101617673B CN 2009101659068 A CN2009101659068 A CN 2009101659068A CN 200910165906 A CN200910165906 A CN 200910165906A CN 101617673 B CN101617673 B CN 101617673B
Authority
CN
China
Prior art keywords
tetraconazole
composition
phonetic phenol
active component
bactericidal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN2009101659068A
Other languages
Chinese (zh)
Other versions
CN101617673A (en
Inventor
郭东岳
张承来
曹明章
毕湘黔
巩自勇
孔建
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Novozon Crop Science Co ltd
Original Assignee
Shenzhen Noposion Agrochemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Noposion Agrochemicals Co Ltd filed Critical Shenzhen Noposion Agrochemicals Co Ltd
Priority to CN2009101659068A priority Critical patent/CN101617673B/en
Publication of CN101617673A publication Critical patent/CN101617673A/en
Application granted granted Critical
Publication of CN101617673B publication Critical patent/CN101617673B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a sterilizing composition which contains tetraconazole and ethirimol, wherein the weight ratio of the tetraconazole and the ethirimol is 80:1-1:80, the content of the total weight of active components accounts for 1-80 percent, and the balance of balance of auxiliary components which is allowed to be used and is acceptable in pesticide. The sterilizing composition can be used for preventing and killing diseases of gramineous grain crops, melons and fruits as well as vegetables, which are caused by ascomycetes, basidiomycetes, adelomycetes. The sterilizing composition has the important functions of synergism, drug resistance delay, cost reduction and prevention and killing scoped expansion, and the like.

Description

A kind of bactericidal composition that contains tetraconazole
Technical field
The present invention relates to a kind of bactericidal composition, especially a kind of binary built bactericidal composition that contains tetraconazole.
Background technology
Tetraconazole (tetraconazole) has another name called fluorine ether azoles, is triazole bactericidal agent, is sterol demethylation inhibitor, inhales conduction in having, and good protection and therapeutic activity are arranged.This medicament all has application on cereal crop, fruit tree, vegetables and ornamental plants, can prevent and treat wheat powdery mildew, loose smut of wheat, wheat rust, the bunt of wheat, wheat glume blight, barley leaf blotch, loose smut of barley, barley banded sclerotial blight, maize head smut, head smut of sorghum, melon and fruit powdery mildew, sigatoka, alternaria leaf spot of apple, pear scab and grape powdery mildew etc.
In the real process of agricultural production, preventing and treating the most incidental problem of disease is the drug-fast generation of germ.The agent of chronic administration agricultural chemicals list lures that easily disease produces serious resistance into.Carrying out compositely through tetraconazole and other active ingredient, is to avoid one of effective way that the resistance germ produces.Composite between the different active ingredients, according to the effect of practical application, judge that composite is synergy or antagonism.The prescription that compound synergic is good can significantly improve actual control efficiency, reduces the usage amount and the access times of agricultural chemicals, thereby delays the generation speed of germ resistance.
In view of this, develop the synergistic composition that contains tetraconazole and have important application value.
Summary of the invention
The bactericidal composition that the purpose of this invention is to provide a kind of efficient, safety, environmental protection is to satisfy the needs of agricultural production, and composition has synergistic effect, can improve preventive effect and is of value to and delays the drug-fast generation of germ.
In order to address the above problem; The inventor has carried out a large amount of tests; It is unexpected that tetraconazole and the phonetic phenol of second found be mixed in the certain proportion scope, has obvious synergistic effect, and the control efficiency that can obviously improve corps diseases also can delay the drug-fast generation of germ.
The phonetic phenol of said second is a kind of miazines bactericide, can absorb through blade and root.Because its action site is different fully with other series bactericidal agents, thus for to the germ of benzimidazole and triazole bactericidal agent generation resistance, prevention and result of treatment that the phonetic phenol of second is all done well.Be mainly used in the control crop powdery mildew at present.
Technical scheme of the present invention is following:
A kind of bactericidal composition that contains tetraconazole; The active component that it is characterized in that composition is tetraconazole and the phonetic phenol of second; The weight ratio of tetraconazole and the phonetic phenol of second is 80: 1~1: 80; Two kinds of active component gross weight percentage compositions are 1~80% in the composition, and all the other are to allow in the agricultural chemicals to use and the acceptable auxiliary element.
As a kind of improvement of the present invention, in the composition the phonetic phenol of active component tetraconazole and second preferably weight ratio be 20: 1~1: 20, two kinds of active component gross weight percentage compositions are 1~50% in the composition.
Composition pesticide of the present invention can be prepared into known method and be fit to any one formulation that agricultural is used, and reasonable formulation is wetting powder, suspending agent, water dispersible granules, missible oil.
The auxiliary agent that uses in the composition of the present invention comprises that solvent, dispersant, emulsifier, stabilizing agent, antifreezing agent, thickener etc. and other are of value to the known substance that active component is stablized and drug effect is brought into play in preparation; All be the various compositions of using or allow use in the pesticidal preparations always; Do not have special qualification, concrete composition and consumption require to confirm through simple experiment according to prescription.
Bactericidal composition of the present invention can be prevented and treated the plurality of plant diseases that is caused by disease funguses such as sac fungi, basidiomycetes, imperfect funguss; Be applicable to control cereal class, various melon and fruit and vegetable disease; Particularly prevent and treat crop pests such as paddy rice, wheat, capsicum, apple, banana, mango, cucumber, tomato, embroider disease, cladosporium leaf and fruit mould of tomato, mango anthracnose, powdery mildew of cucumber, banana freckle, citrus scab, leaf spot of peanut etc. like wheat powdery mildew, apple.
Compared with prior art, beneficial effect of the present invention is:
1, synergistic effect is remarkable.Composition is compared bactericidal effect with single agent and is obviously improved owing to increased the action site to the target fungi,
2, after drug effect improved, the amount of application of active ingredient and the minimizing of medication number of times had reduced drug cost, had reduced residue of pesticide and to the pollution of environment.
3, help resistance management.The mechanism of action of two active ingredients is different fully in the composition, has reduced the single selection pressure to germ, does not have mutual pesticide resistance, therefore can avoid and delay the drug-fast generation of germ.
Embodiment
In order to make the object of the invention, technical scheme and advantage clearer, the present invention describes with following specific embodiment, but the present invention is limited to these examples absolutely not.The following stated is merely the present invention embodiment preferably, only in order to explain the present invention, can not therefore be interpreted as the restriction to claim of the present invention.Should be pointed out that all any modifications of within spirit of the present invention and principle, being made, be equal to replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with accompanying claims.
1, wetting powder embodiment
Pesticide activity component tetraconazole and the phonetic phenol of second, auxiliary agent, filler are mixed the mixed again wetting powder that gets behind comminution by gas stream in proportion.Capital equipment: mixer, airslide disintegrating mill.
The phonetic phenol wetting powder of embodiment 1:21% tetraconazole second
94% tetraconazole (active component) 21.28g
The phonetic phenol of 95% second (active component) 1.05g
Sodium lignin sulfonate (dispersant) 5g
Lauryl sodium sulfate (wetting agent) 5g
Bentonite (filler) 5g
Diatomite 62.67g
The phonetic phenol wetting powder of embodiment 2:80% tetraconazole second
94% tetraconazole (active component) 31.91g
The phonetic phenol of 95% second (active component) 52.63g
Sodium lignin sulfonate (dispersant) 5g
The withered powder of tea (dispersant) 5g
Draw back powder (wetting agent) 1g
White carbon (filler) 1g
Attapulgite 3.46g
2, suspending agent embodiment
Press formula rate; With pesticide activity component tetraconazole with after the phonetic phenol of second, surfactant, thickener, film forming agent, carrier or filler and part water mix, through high speed shear, the wet method sand milling; Process semi-finished product, moisturizing mixes filtration and promptly obtains finished product after analyzing.
The phonetic phenol suspending agent of embodiment 3:40.5% tetraconazole second
94% tetraconazole (active component) 0.53g
The phonetic phenol of 95% second (active component) 42.11g
Methyl naphthalene sulfonate formaldehyde condensate (wetting agent) 10g
Xanthans (thickener) 2g
Bentonite (filler) 1g
Glycerine (antifreeze) 5g
Water 39.36g
The phonetic phenol suspending agent of embodiment 4:11% tetraconazole second
94% tetraconazole (active component) 10.64g
The phonetic phenol of 95% second (active component) 1.05g
Sodium lignin sulfonate (dispersant) 1g
Magnesiumaluminumsilicate (auxiliary material) 1g
Ethylene glycol (antifreezing agent) 5g
White carbon (filler) 2g
Bentonite (filler) 2g
Water 77.31g
3, water-dispersible granules embodiment
Pesticide activity component tetraconazole is mixed with the phonetic phenol of second, auxiliary agent and filler in proportion,, add the water of 15-20% then, make the water dispersible granules product through kneading, granulation, drying, screening through comminution by gas stream.Capital equipment: mixer, airslide disintegrating mill, kneader, Squeezinggranulator, drying equipment (drying room or fluid bed).
Embodiment 5:50% tetraconazole ethirimol water dispersible granules
94% tetraconazole (active component) 10.64g
The phonetic phenol of 95% second (active component) 42.11g
Sodium lignin sulfonate (dispersant) 5g
The withered powder of tea (dispersant) 2g
Lauryl sodium sulfate (wetting agent) 2g
Bentonite 38.25g
Embodiment 6:10.5% tetraconazole ethirimol water dispersible granules
94% tetraconazole (active component) 0.53g
The phonetic phenol of 95% second (active component) 10.75g
Sodium lignin sulfonate (dispersant) 5g
Methyl naphthalene sulfonate formaldehyde condensate (dispersant) 15g
Lauryl sodium sulfate (wetting agent) 5g
Sodium alginate (filler) 5g
Potter's clay 58.72g
4, missible oil embodiment
Pesticide activity component tetraconazole is mixed with the phonetic phenol of second, emulsifier, partial solvent in proportion, in modulation kettle, mix and stir, after treating to dissolve fully, add remaining solvent lentamente again, obtain uniform oil phase after fully stirring, process the missible oil product.
The phonetic phenol missible oil of embodiment 7:40.5% tetraconazole second
94% tetraconazole (active component) 42.55g
The phonetic phenol of 95% second (active component) 0.53g
Farming newborn 600# (emulsifier) 10g
Xylol (solvent) 46.92g
The phonetic phenol missible oil of embodiment 8:1% tetraconazole second
94% tetraconazole (active component) 0.53g
The phonetic phenol of 95% second (active component) 0.53g
Farming newborn 600# (emulsifier) 10g
Xylol (solvent) 88.94g
Indoor biometrics application implementation example:
The phonetic phenol of tetraconazole and second is composite to the powdery mildew of cucumber Toxicity Determination
Subjects: the powdery mildew of cucumber bacterium (Sphaerotheca fuligenea) of picking up from the field
Test method: with reference to " the agricultural industry criteria NY/T 1156.11-2008 of the People's Republic of China (PRC) " pot-culture method.2 leaf period cucumber seedlings choosing the growing way basically identical are as experiment material, and 5 basin cucumber seedlings are selected in each processing for use, and numbering supplies examination.Get the sick leaf of the powdery mildew of cucumber of picking up from the field, above cucumber seedling, evenly shake off conidium and inoculate, carry out chemicals treatment behind the inoculation 24h, test medicine is referring to table 1.Under 50PSI pressure, spray every basin 5mL with the Potter spray tower.To spray the blank that is treated to of equivalent clear water.After the spraying cucumber seedling being put into the greenhouse cultivates.Investigate whole blades and record, calculate disease index and control efficiency according to the morbidity grade scale of powdery mildew of cucumber behind the 7d.
Figure G2009101659068D00072
Control efficiency is converted into probability value (y), and liquor strength (mg/L) converts logarithm value (x) to, concentration EC in calculating the virulence equation and suppress with method of least squares 50, according to the toxicity index and the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun medicament.
Actual measurement toxicity index (ATI)=(standard medicament EC 50/ confession reagent agent EC 50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
CTC≤80, the composition performance is antagonism, 80<CTC<120, the composition performance is summation action, CTC>=120, the composition performance is synergistic effect.
Table 1 is measured the result and is shown that tetraconazole and Fluoxastrobin have synergistic effect to the powdery mildew of cucumber bacterium between proportioning 80: 1~1: 80, and especially between 20: 1~1: 20, synergistic effect is more obvious, and co-toxicity coefficient is more than 200.
The phonetic phenol of table 1 tetraconazole and second is composite to powdery mildew of cucumber bacterium Toxicity Determination result
Handle EC 50 ATI TTI Co-toxicity coefficient
(mg/L) CTC
Tetraconazole 9.43 100.0 - -
The phonetic phenol of second 10.16 92.81 - -
Tetraconazole 1: the phonetic phenol 80 of second 7.81 120.74 92.90 129.97
Tetraconazole 1: the phonetic phenol 40 of second 7.10 132.82 92.99 142.83
Tetraconazole 1: the phonetic phenol 20 of second 5.01 188.22 93.16 202.05
Tetraconazole 1: the phonetic phenol 5 of second 4.68 201.50 94.01 214.33
Tetraconazole 1: the phonetic phenol 1 of second 4.29 219.81 96.41 228.00
Tetraconazole 5: the phonetic phenol 1 of second 4.03 234.00 98.80 236.83
Tetraconazole 20: the phonetic phenol 1 of second 3.98 236.93 99.66 237.75
Tetraconazole 40: the phonetic phenol 1 of second 5.82 162.03 99.82 162.31
Tetraconazole 80: the phonetic phenol 1 of second 7.25 130.07 99.61 130.18
Field efficacy application implementation example:
The phonetic phenol of tetraconazole and second is composite to preventing and treating the field trial of powdery mildew of cucumber.
(1) test is handled: this test medicine is handled and consumption is seen table 2, and the contrast medicament is respectively commercially available agricultural chemicals 4% tetraconazole aqueous emulsion and the phonetic phenol suspending agent of 25% second, and other establishes the clear water contrast.
(2) test method: test and Selection is carried out the condition basically identicals such as cucumber growing way, other agricultural chemicals and rich water quality management that each is handled in the more serious green cucumber plot of powdery mildew over the years.Carry out the dispenser first time in the powdery mildew of cucumber initial stage of origination, whenever sprayed once later, spray altogether 3 times at a distance from 7 days.10 days investigation powdery mildew incidences before medicine and after the 3rd dispenser, repeat four sub-districts of every processing, and 2 strains are investigated in every sub-district, and whole blades are investigated in every strain, the classification record.Calculate disease index and preventive effect.
Figure G2009101659068D00081
Figure G2009101659068D00091
(3) result of the test is following:
Can be found out by field control effectiveness test result (table 2): the agent of the phonetic phenol list of tetraconazole or second is respectively 81.10%, 80.31% to the preventive effect of powdery mildew of cucumber; And embodiment of the invention bactericidal composition is equal to or less than in the unit are effective ingredient consumption under the situation of corresponding single agent consumption, and preventive effect but is significantly increased, and minimum preventive effect is 86.46%; Be up to 95.26%; When particularly the phonetic phenol weight ratio of tetraconazole and second was 20: 1~1: 20 (embodiment 1,2,4,5,6,8), preventive effect promoted particularly evident, and the powdery mildew of cucumber preventive effect has been reached more than 93%; Therefore; From field control effectiveness test, the phonetic phenol of tetraconazole and second is composite good to the powdery mildew of cucumber control efficiency, has synergistic function.
The composite field test results of the phonetic phenol of table 2 tetraconazole and second to powdery mildew of cucumber
Supply the reagent agent Dosage (ga.i./ha) Disease index before the medicine Disease index behind the medicine Preventive effect (%)
4% tetraconazole EW 50 1.2 6.7 81.10
The phonetic phenol SC of 25% second 250 1.1 6.4 80.31
Embodiment 1 66 1.3 2.5 93.49
Embodiment 2 104 0.8 1.4 94.08
Embodiment 3 230 0.9 3.6 86.46
Embodiment 4 60 1.3 2.2 94.27
Embodiment 5 150 1 1.4 95.26
Embodiment 6 200 1.3 2.3 94.01
Embodiment 7 45 1.1 4.1 87.38
Embodiment 8 76 1.2 1.7 95.21
CK - 1.1 30.6 -

Claims (6)

1. bactericidal composition, it is characterized in that: active component is tetraconazole and the phonetic phenol of second, and the weight ratio of tetraconazole and the phonetic phenol of second is 80: 1-1: 80.
2. bactericidal composition according to claim 1 is characterized in that: the weight ratio of active component tetraconazole and the phonetic phenol of second is 20: 1-1: 20.
3. according to claim 1 or 2 each described bactericidal compositions, it is characterized in that: two kinds of active component gross weight percentage compositions are 1~80% in the composition.
4. bactericidal composition according to claim 3 is characterized in that: two kinds of active component gross weight percentage compositions are 1~50% in the composition.
5. according to claim 1 or 2 each described bactericidal compositions, it is characterized in that: the formulation of composition is wetting powder, suspending agent, water dispersible granules or missible oil.
6. according to claim 1 or 2 each described bactericidal compositions, it is characterized in that: composition is applied to prevent and treat cereal class, fruit tree and vegetable disease.
CN2009101659068A 2009-08-12 2009-08-12 Sterilizing composition containing tetraconazole Active CN101617673B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009101659068A CN101617673B (en) 2009-08-12 2009-08-12 Sterilizing composition containing tetraconazole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009101659068A CN101617673B (en) 2009-08-12 2009-08-12 Sterilizing composition containing tetraconazole

Publications (2)

Publication Number Publication Date
CN101617673A CN101617673A (en) 2010-01-06
CN101617673B true CN101617673B (en) 2012-06-06

Family

ID=41511224

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009101659068A Active CN101617673B (en) 2009-08-12 2009-08-12 Sterilizing composition containing tetraconazole

Country Status (1)

Country Link
CN (1) CN101617673B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101779674B (en) * 2009-12-16 2012-07-04 福建新农大正生物工程有限公司 Sterilization composition containing tetraconazole

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006015865A1 (en) * 2004-08-12 2006-02-16 Syngenta Participations Ag Fungicidal compositions
CN101106903A (en) * 2005-02-04 2008-01-16 三井化学株式会社 Plant pathogen control composition and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006015865A1 (en) * 2004-08-12 2006-02-16 Syngenta Participations Ag Fungicidal compositions
CN101106903A (en) * 2005-02-04 2008-01-16 三井化学株式会社 Plant pathogen control composition and method

Also Published As

Publication number Publication date
CN101617673A (en) 2010-01-06

Similar Documents

Publication Publication Date Title
CN101690483B (en) Bactericidal composition containing triazole class compounds
CN101690480B (en) Pesticide composition containing methoxy acrylic bactericide and application thereof
CN101595887A (en) A kind of bactericidal composition that contains Prochloraz
CN101647441B (en) Sterilization combination containing azoxystrobin and application thereof
CN101647454A (en) Sterilizing composition containing cyprodinil
CN101816308A (en) Bactericidal composition
CN101653139A (en) Compound bactericidal composition containing boscalid
CN101669524B (en) Bactericide composition with tetraconazole
CN101653131B (en) Bactericidal composition containing azoxystrobin
CN101658173A (en) Sterilization composition containing tetraconazole
CN101669474A (en) Bactericidal composition containing kresoxim-methyl phenylate
CN101779645A (en) Azoxystrobin composite and application thereof
CN101617671B (en) Combination sterilization composition
CN101690489A (en) Bactericidal composition
CN101524069B (en) Sterilizing composition containing Hexaconazole
CN101779636B (en) Bactericidal composite containing tetraconazole
CN103563910A (en) Bactericidal composition containing prothioconazole and validamycin and application thereof
CN104054712B (en) Sterilization composition containing boscalid
CN101617673B (en) Sterilizing composition containing tetraconazole
CN101647442B (en) Mixed sterilization combination
CN101632375B (en) Pyricularia amide compound sterilization composition
CN101849546A (en) Pesticide composition
CN106577680A (en) Bactericide and application thereof
CN101536690A (en) Epoxiconazole and kresoxim-methyl sterilizing composite
CN105831132A (en) Sterilization composition containing benzothiostrobin and fluoride ether bacteria amide

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CP03 Change of name, title or address

Address after: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang

Patentee after: Shenzhen Novozon Crop Science Co.,Ltd.

Country or region after: China

Address before: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang

Patentee before: SHENZHEN NOPOSION AGROCHEMICALS Co.,Ltd.

Country or region before: China

CP03 Change of name, title or address