CN101612033B - A device for determining anterior chamber depth of an eye - Google Patents
A device for determining anterior chamber depth of an eye Download PDFInfo
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- CN101612033B CN101612033B CN200910140945.2A CN200910140945A CN101612033B CN 101612033 B CN101612033 B CN 101612033B CN 200910140945 A CN200910140945 A CN 200910140945A CN 101612033 B CN101612033 B CN 101612033B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
- A61B3/15—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
- A61B3/156—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for blocking
- A61B3/158—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for blocking of corneal reflection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/1005—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/10—Eye inspection
Abstract
Without any contact combination apparatus determines an eye's length of axis (AL), the cornea's curvature (HHR) and the main chamber depth (VKT). This assists the selection of intra-ocular lenses to be implanted in the eye.
Description
Technical field
The present invention relates to heed contacted measure eyes axial length and/or corneal curvature and/or anterior chamber depth, especially iol
The apparatus and method of measurement.
Background technology
Schematically show in Fig. 1 by human eye longitudinal cross-section.Generally by ultrasound wave, people is measured with contact method
Axial length al of eye.
Illustrate other measuring method in de 3201801 and us 5673096, de4446183 a1.By known
Cornea instrument (keratormeter)/ophthalmology instrument (ophthalmometer) determine the curvature-corneal radii hhr (dd of cornea
251497, us 4572628, us 4660946, us 5212507,5325134).By ultrasound wave or by belonging to gap lamp
Auxiliary unit (anterior chamber depth measuring instrument, the regulation of through the slit lamp image) carries out the measurement of anterior chamber depth vkt.
Especially before cataract operation, but when the process inspection in school myopia and aniseikonia determine,
Also must determine that these are also important measured value for the selection of the intra-ocular lens iol that should implant.Lead in clinical practice
Often at least measure these values by two kinds of instruments (the such as scanning of ultrasound wave a type and automatic cornea instrument).In the optics calculating iol
These measured values are adopted in the formula of effect.Instrument type difference by being adopted may lead to affect the various each of iol selection
The error of sample.
Content of the invention
The task of the present invention is for these measurement error depending on instrument to be reduced to minimum.
By the present invention, this task is solved by a kind of device of the anterior chamber depth for determining eyes.Described device has
A) via imaging microscope group, towards the incident slot-shaped photograph of eyes (14) on the downside of for an angle observing axle
It is bright,
B) there is concatenation signal processing, collection is derived from the receiver apparatus of the dispersion image of eyes (14), and
C) controller after described receiver apparatus.
According to a kind of advantageous embodiment according to assembly of the invention, described slot-shaped illumination includes light source and to shine
The gap that bright direction is arranged below in light source.
According to a kind of advantageous embodiment according to assembly of the invention, described light source is led.
According to a kind of advantageous embodiment according to assembly of the invention, described slot-shaped illumination includes image opticss device
Part and described image forming optics are the image forming optics of shifting ground construction.
According to a kind of advantageous embodiment according to assembly of the invention, described slot-shaped illumination includes a series of white lights
led.
According to a kind of advantageous embodiment according to assembly of the invention, the receiver apparatus of this device are ccd shootings
Machine.
Advantageously determine all necessary at that time of eyes by the present invention by a kind of apparatus and corresponding measuring method
Parameter.
Similarly realize the necessary regulation making instrument that the correction of patient is possibly realized in this device.
The same calculating carrying out iol by this apparatus.Therefore transmitting difference to the computer carrying out iol calculating
Also cancel data degradation or data distortion during the measured value of instrument.
Brief description
Fig. 1 is the longitudinal cross-section by human eye；
Fig. 2 is the schematic structure for carrying out heed contacted measure in human eye；
Fig. 3 is the front view of the instrument in direction of observation figure 2 above；
Fig. 4 is the several light paths between eyes and ccd video camera；
Fig. 5 is the control block diagram of the device for Fig. 2；
Fig. 6 a, Fig. 6 b is the distinctive transmissivity curve of two beam splitters of the device of Fig. 2；
Fig. 7 is the image of the eyes of shooting machine testing of Fig. 2, is used for illustrating the determination of another anterior chamber depth (vkt)；With
Fig. 8 a, Fig. 8 b is the device schematically shown for obtaining vkt.
Specific embodiment
Below by schematic diagram in detail the present invention and its advantage are described in detail.
The schematic configuration of instrument is illustrated in Fig. 2.In order to measure axial length by the light of laser diode 1 through Michael
Inferior interferometer 3-5, dichroic cube 8 and diffraction optical element doe9 are imaged onto in patient's eyes 14, Michelson's interferometer
3-5 by having illuminator 4, here for a kind of fixed reference arm r1 of three conjunction prisms, with by by other illuminators 5 (three
Close prism) a kind of scalable reference arm r2 represented by diverse location, and be used for overlapping institute's reflected beam in r1 and r2
A kind of partial beam-dividing cube 3 forms.Diode 7 monitors the luminous power of laser diode 1.Cornea and view by eyes 14
The part beam that film is reflected overlaps each other, and by doe9, the light splitting with the λ/4 plate p1 for rotatory polarization plane is stood
Cube 8, the dichroic cube 15 with λ/2 plate p2 by these part beam line focus elements, here for achromat 16
It is imaged onto on avalanche photodide apd 17.Here carries out axial length by illustrated known method for example in us5673096
Measurement.
In order to observe eyes and the reflection being formed, by achromat 22 by reflection light (light coming from eyes)
A part be imaged onto on ccd video camera 23 through minute surface 20.Achromat 18,19 heres are outwards shown.Aperture 21 exists
This is located on the position withdrawn from.
In order to measure corneal curvature hhk, outstanding by 6 under the angle to about 18 ° of optical axis a1 similar in appearance to dd 251497
It is infrared led 10 to illuminate eyes 14, is located at drawing when exemplarily illustrating in FIG in these infrared led 10
In plane two.Eyelet aperture 10a has been disposed to be used for generating point-like illumination image after led.
Collimation for diode light arranges six lens 11 on illumination direction after led.By this light source
The image that (as the reflection of cornea) is formed in eyes is through dichroic cube 8 and 15 and achromat 18 and 19 imaging
To on ccd video camera.Doe9 advantageously outwards shows here, but can also keep in the light path.Achromat
22 outwards show.
For determining vtk, by led diode 12 under about 33 ° of angle, gap aperture 12a and cylindrical lenss 13
Illuminate each eye slot-shapedly.By the produced dispersion image of cornea and crystalline body front surface through dichroic cube 8 and 15
And achromat 18 and 19 is imaged onto on the ccd video camera 23 in the doe especially outwards showing.Achromat 22
Outwards show.
Fig. 3 is front view on direction of observation for the instrument, and here has omitted the known gap lamp cross adjusting for x/y/z
The diagram of workbench.
It is seen that: doe 9 (position of optical axis in instrument be marked on its central point a1), with positioned at this it
Sightless led 10 afterwards determining the lens 11 of corneal curvature, cylindrical lenss 13 He that the gap for measuring vkt is imaged
Illumination for eyes 14 and the six ir diodes 24 correcting.
The measuring task by the light path a-d leading to ccd video camera 23 from eyes 14 should more accurately be illustrated by Fig. 4.
The correction to eyes for light path c: the instrument
Eyes are located on the focal length of achromat 18, towards infinite distance imaging, and are imaged onto ccd through achromat 22 and take the photograph
In the plane of camera.Achromat 19 is outwards shown here.
There is provided positioning light by laser diode (ld) or led 1 to patient, so as he by eye pupil towards optical axis
Direction orients.It is necessary the larger fragment (such as 15mm) of eyes 14 is imaged onto on ccd video camera.Doe is small due to it
Efficiency (in focusing block about 5%) is poorly suited for iris structure imaging so that have solid imaging scale by disappearing
The optical system of aberration lens 18 and 22 composition is implemented as picture.Doe here is preferentially outwards shown.In order to not produce to patient
Raw additional positioning is stimulated, by the ir diode 24 (Fig. 2) being especially characterized with broad reflection characteristic (big half-value angle)
(such as 880nm) carries out the illumination of eyes 14.Carry out instrument through known in the adjustable gap in x/y/z direction lamp cross table
The correction to patient for the device.The vcm3405 of Philip for example can be adopted as ccd video camera.The illumination of eyes is necessary, with
Just patient can be adjusted to instrument even in dark room.Region for 15mm should diffusely be illuminated as far as possible,
Light source be can be by the imaging of cornea and cannot be avoided (because effect of cornea blistering minute surface).
Basic idea is here, and the device being used for illuminating advantageously is used in the correction of patient's eyes simultaneously.
Have the six of larger half-value angle in the upper arrangement of circumference (sometimes: identical circumference as when cornea instrument measures)
Individual infrared led 24.These led 24 are imaged onto 6 points on ccd video camera on cornea.In lc display or prison
Patient's eyes are shown on visual organ lively；Lcd/ monitor additionally showing, a kind of circle/cross hairs are used for centre mark.For
The positioning of eyes must adjust 6 points-realize this point by mobile cross table with one heart for shown circle；If
These point be centering and high-visible if, patient is correctly adjusted in height/side/depth.Patient oneself court
Instrument looks-therefrom projection patient must navigate to calibration of laser diode 1 thereon or led1a.Permissible at the center of pupil
See laser-bounce.
A kind of additional regulation auxiliary should be shown on lc display or monitor.Interference signal for axial length measuring instrument
Detection be scheduled that a kind of avalanche photodide apd.When patient's eyes are on the optical axis of measuring instrument, before cornea
Surface reflection correction laser diode 1 or led 1a；By the image formation by rays of reflection on apd.Therefore its (phase is generated by apd
Right) height represent patient's eyes centering a yardstick d. c. voltage signal.By this d. c. voltage signal through a/d transducer
It is conveyed to the computer of inside, and (such as bar/circle) is shown on lcd therefrom in an appropriate form.Therefore pass through bar/circle
Different size the other information of the correcting state for patient's eyes is sent to operator.
Light path d:alm
Through the doe as parallel light path and through achromat 22 by the catoptric imaging of laser diode 1 (such as 780nm)
To on ccd video camera 23, here shows in the case that the microscope group 18,19 for observation and Reflective regulation is outwards shown and is about
The eyes fragment of 5mm.In order to maximum energy is transferred on apd 17, will be total on dichroic cube 15 shown in fig. 2
Most of about 80-95% of being advantageously more than of energy exports on apd；The light of therefore only about 20-5% is fallen ccd and is taken the photograph
On camera.
Light path b: cornea instrument
Preferentially it is illuminated similar in appearance to dd251497 by six ir diodes 10 (such as 880nm), so that without prejudice to will
Patient's eyes 14 are fixed on the positioning light of ld 1 or led 1a.
The resolution requirement that ccd video camera 23 gives is not more than the imaging in the region of about 6mm on eyes 14, to reach
The certainty of measurement of 0.05mm.Preferentially again through the effect outwards showing elimination doe, and achromat 18 and 19 is realized
The imaging of 6 corneal reflex images.
Make to improve that certainty of measurement unrelated to the distance of instrument with patient's eyes to a great extent is used has:
- telecentricity the aperture 21 that the aperture of measurement is restricted on particular less than 0.05, and
- be located between led and patient's eyes, independently maintain the constant standard of angle of incidence with the axial location of patient's eyes
Straight collimator 11.
The eyelet aperture 10a that precise calibration through making cornea instrument measurement point is possibly realized advantageously carries out led light
Imaging.Collimating light pipe focal length should be greater than 50 times of efficient light sources size, independently to reach being wished of radius measurement with position
The certainty of measurement hoped.
Light path a:vkt
Because when observing the optical cross-section in eye, light scattering plays conclusive effect it is necessary to select shortwave as far as possible
The light source of (such as 400-600nm) is used for the illumination of eyes 14.
Even determine in vkt to reach the certainty of measurement of required 0.1mm it is necessary to by being not more than on eyes 14
The regional imaging of about 6mm is on ccd video camera 23.
Pass through achromat 18 and 19 real under conditions of avoiding doe effect or in the case of the doe outwards showing
Existing this point.Achromat 22 is outwards shown.
Telecentricity aperture 21 that inwardly swing in here or regulation must have (preferential be more than 0.07-such as 13mm
Aperture) larger diameter, only minimally to reduce the light intensity of the weak dispersion image of formed light when vkt measures.
Aperture 21 is adjustable therefore at least two positions, or tradable with second aperture.
Laterally under fixing angle, this is illuminated by bright light gap and test eye.With optical system 18,19,
21 optical cross-sections forming the here on eyes are imaged onto on ccd video camera.Illumination and observation here form preferential about 33 °
Fixing angle.
Fig. 8 a, b schematically show the device for obtaining vkt, display lighting direction in Fig. 8 a, and show in figure 8b
Detection direction.
Predetermined distance is had to fixed width gap 12a by a line, the strong led of light 12 is forming light gap.
The gap illuminating in this way 12a is imaged onto on test eye as slot image s by cylindrical lenss 13.It is contemplated that adopting
Led typically has the life-span of at least 10000 hours.(as comparing: Halogen light 100-200 hour).Do not exist due to
The wear phenomenon of high-temperature load as on Halogen light.
Imaging microscope group 18,19 realization through schematically showing will have tester's eye imaging of important image segments to especially
On its ccd sensor.Telecentrically carry out being imaged-telecentricity aperture 21, to reduce the impact of tester's correction.In monitor or lc
Video signal is shown so that operator can carry out tester's correction and measurement under not being subject to compulsory posture on display.Survey
Amount method is not based on measurable displacement of parts of images；Therefore pupil divides and can cancel.By frame grabber fg, ccd is taken the photograph
The signal of camera 23 is received in the memorizer of computer c.By suitable image processing software obtain in cross-sectional image from
Wherein calculate the distance of vkt (precision 0.1mm).(for example passing through to exclude ambient light) reaches the improvement of important picture material, adopts
Method be synchronized with an appropriate form video half image ground beat switch on and off illumination led.
The achromat of one regulation focal length is satisfied with eye imaging to ccd video camera.Answer depending on eyes
The desired image segments of imaging carry out the determination of focal length.The aperture 21 meeting telecentric condition is arranged in the figure of achromat
On the focal length of image side.This simple structure of imaging system ensures the probability being integrated in other system uncomplicatedly.
Enter to be about to positioning light 1 through the beam splitter 8 in Fig. 8 b, 1a (led) combines in focus.Light source is integrated in observing
(such as tester navigates to led1a or laser diode 1 thereon) in system.Monitor or lc display show and takes the photograph
The video signal of camera.Tester adjustment and measurement during operator it is believed that tester be properly positioned-and
Therefore measurement result is undeformed.By cylindrical lenss, the gap illuminating in this way is imaged onto on test eye 14.
There is 0.1 big small-bore, the imaging being slightly offset from 1:1 imaging in 0.3mm width gap, and proved using white light led
Particularly advantageous.
Imaged microscope group 18,19 is realized sensing tester's eye imaging with important image segments to especially ccd
On device.Telecentrically it is imaged, to reduce the impact of tester's correction.Monitor or lc display showing, video is believed
Number so that operator can carry out tester's correction and measurement under not being subject to compulsory posture.
For example by frame grabber, the signal of ccd video camera is received in the memorizer of computer.Scheme by suitable
As process software obtain in cross-sectional image from the distance wherein calculating vkt (precision 0.1mm).(for example passing through to exclude ambient light)
Reach the improvement of important picture material, the method for employing be synchronized with an appropriate form video half image ground beat connect and
Disconnect illumination led.
Below by Fig. 7 narration, how to obtain vkt by the image on ccd matrix.With calibration of laser or positioning led
Reflected image fi illustrate by ccd camera acquisition eye image and connect illumination 1 when cornea and lens sl dissipate
Penetrate light sh.
The distance of the leading edge of cornea and lenticular dispersion image is determined in digital video recording
The starting point of image procossing is (n takes advantage of) one secondary image directly in succession recorded: has the figure of the slit illumination of connection
(" bright image "), has the image (" dark image ") not having slit illumination of positioning lamp image.To be entered with following key step
Row is processed:
● test pupil in dark image: under considering boundary condition based on tape figure select for binarization threshold
Value.Determine the ellipse of external pupil by analyzing and processing the covariance matrix of binary picture.
● the anchor point in detection pupil in dark image: determine that its gray value is located at grey value profile in dark image
All regions connecting each other on 0.9 quantile.Determine depend on area, shape and to pupil center's point distance each
The probability scale in region.The center of gravity selecting most probable region is as fixing point.
● calculating difference image (bright image deducts dark image) and in error image by the noise suppression of medium filtering.
● determine the boundary curve of the dispersion image of slit illumination in error image: based on band under considering boundary condition
Select the threshold value for binarization bar figure.In the given range around anchor point, rough detection surmounts place as threshold value
Edge.It is expert in scattergram and finely detect as grey value profile, from the nearest turning point place of rough test position
Edge.(remove farthest from average edge curve in point by eliminating reflective edges in the non-feature point detection in boundary curve
Given part).
● determine cornea and crystalline lenses dispersion image sh, sl (in units of pixel) leading edge apart from x: by ellipse
Approach boundary curve (reduce square error and) constrainedly.Calculate these oval with by the horizontal intersection point of anchor point away from
From.
Calculating anterior chamber depth from above-mentioned distance:
To there is (imaging scale of substitution microscope group and the ccd square being scaled in units of mm apart from x in units of pixel
The pixel size of battle array)
R=corneal radii,
The refractive index of n=room liquid
The angle of ω=between illumination and observation
When the image of positioning lamp is located on the leading edge of crystalline lenses dispersion image, as represented in Fig. 7, this
Formula is suitable for exactly；Positioning lamp image otherwise can be obtained with a distance from the leading edge of crystalline lenses dispersion image, and from this
The correction value of anterior chamber depth can be obtained by known imaging formula in the absolute value of " eccentric ".Particular by above-mentioned cornea instrument dress
Put to measure corneal radii.
Summarized below combine 3 necessary measured values and during trimming process it should be noted that the overview that adjusts of characteristic:
As would know that from this summary, different wavelength period are adopted on different measuring task.Dichroic cube
8 and 15 heres are significant, because in these local illumination light paths separated from each other, observe light path and measurement light path.
Under the conditions of the linear polarization considering laser diode 1, special beam splitter layer realizes these tasks.
Dichroic cube 8:
Farthest reflection should carry out the laser of interferometer on the direction of eyes 14；Laser from eyes 14 should be gathered around
There is the transmittance of maximum.
The ir that beam splitter layer in dichroic cube (square glass prism) 8 must additionally measure for the measurement of cornea instrument and vkt
There is the transmittance of maximum with vis light portion.
Due to being related to linearly polarized photon on ld 1 (such as lt023 Sharp), the dielectric multiple layer with polarization can
Preferentially to be adopted.Distinctive transmissivity curve is illustrated in Fig. 6 a.(about 98%) reflection is from ld1's as much as possible
Vertical polarized light (s- pole, 780nm).
Circular polarization light is generated by λ/4 plate.Therefore after the plate of λ/4 again linear polarization reflected by eyes 14
Light；Polarization direction but have rotated 90 ° (parallel polarization, p- poles).Beam splitter layer on 780nm is for this vibration side
To the transmittance with approximate 100%.Ir and vis light emitting diode sends non-polarizable light.
As would know that from Fig. 6 a, 6b, in 420 to 580nm wavelength period and in 870 to 1000nm wave band
In the transmittance of beam splitter layer be greater than the 90% of not polarized light.
The construction of layer: dichroic cube 8:
This pole dichroic cube except its general function-the pole beam splitter effect in provision wavelengths section-in addition to, full
The additional of highly transmissive that foot neutralizes in visible wavelength section (420...560nm) near infrared band (870...1000nm) will
Ask.
Layer design meets the these requirements of about 46 ° of narrow ranges of incidence angles.The material being adopted is from refractive index of substrate, glue
The refractive index aspect of mixture refractive index and coated substance matches each other.Following material has been selected for this special purposes
Material:
Substrate: sf2 n=1.64
Adhesive n=1.64
H n=1.93
L n=1.48
Design is made up of 17 alternating layer hl.Hf02 is h, and sio2 is l.Can be by suitable for comparable beam splitter
The refractive index of substrate and coated substance and angle of incidence is selected to make suitable beam splitter.
Parameter: highly transmissive is from 420...560nm, non-polarizable
Highly transmissive is from 870...1000nm, non-polarizable
Pole span (polteilung) 780 ± 20nm
Example:
Dichroic cube 15:
The laser about 80-95% from dichroic cube 8 should be reflected in about 20-5% transmittance.Beam splitter layer should
Ir and vis light portion is had to the transmittance of maximum.
This layer to be realized by pole beam splitter again by the beam splitter layer being similar in 8 in its performance.It is arranged in light splitting
λ/2 plate on cube 15 rotates 90 ° the polarization direction reaching light so that s-pol component falls dichroic cube again
On 15.
Adjust above-mentioned light splitting ratio by changing layer 8.Transmittance is for the non-polarizable light in ir and vis wave band
It is more than 90%.
The construction of layer: dichroic cube 15:
In addition to the requirement in the reflection s- pole of the 80-95% on 780nm ± 20nm wavelength, this dichroic cube
Meeting the additional of highly transmissive neutralizing near infrared band (870...1000nm) in visible wavelength section (420...560nm) will
Ask (Fig. 6 b).
Layer design meets about 46 ° of the narrow these requirements injecting angle range.The material being adopted is from refractive index of substrate, glue
The refractive index aspect of mixture refractive index and coated substance matches each other. following material has been selected for this special purposes
Material:
Substrate: bk7 n=1.52
Adhesive n=1.52
H n=1.93
L n=1.48
Design is made up of 13 alternating layer hl.
For comparable beam splitter can by the refractive index of appropriately selected substrate and coated substance and angle of incidence Lai
Make suitable beam splitter.
Parameter: highly transmissive is from 420...560nm, non-polarizable
Highly transmissive is from 870...1000nm, non-polarizable
Reflection s- pole about 80-95%780 ± 20nm
Example:
In order to adjust and control such as microscope group 18,19,22, as aperture 21 etc., all adjustable unit and optics are first
Part, is scheduled that central control by Fig. 5.
Different imaging scale under conditions of considering doe effect make the transformation process in instrument necessitate.Especially
It flexibly realizes these transformation processs with program control.
Have been carried out a kind of compact instrument that primary electron module is integrated into.Core members are a kind of embedded Pentium
Controller c, by display d (display of checked eyes 14 and the menu-guided of operator), keyboard, Genius mouse, foot switch
It is connected on this Pentium controller c with the printer as ancillary equipment.
alm
Via controller c carries out laser diode 1 and interferometer slide plate is's (the mobile prism 5 being connected with measuring system)
Control.Impact in order to reduce eye activity must realize short time of measuring (being shorter than 0.5 second).The letter being generated by apd 17
In number arriving signal processing unit se, it is amplified depending on signal magnitude, subsequent frequency is selectively amplified, and uses phase
When the rate of scanning in about 4 times of useful signal frequencies obtains analog-to-digital conversion.Numeral is received by the high-speed port hs of Pentium platform
Formula scan values.There by Fourier Tranform, carry out digital signal process with there is no the outside reference frequency being generated.?
Display upper table shows signal；Stroke measurment system provides and is subordinated to this axial length number.
Cornea instrument
Controller c is control with ccd video camera 23 and is connected with diode 10.In the tune for keratometry
Especially diode 10 is run in lasting light mode during section, so that the flicker of the corneal reflex image preventing from being shown on lcd.
Switch on and off these diodes by image in measurement process；It is synchronized with ccd video camera 23 for this controller c
Pattern pulse ground control diode 10, that is, diode be to turn in an image and be to disconnect in next image
's.
After the subtracting each other of two successive images (difference is formed) people become the secondary ground of image only also obtain cornea by led
The reflection of 10 generations, and exclude interfering reflection of ambient light.
The reflected image being formed on ccd video camera 23 by frame grabber fg digitized, and in Pentium platform (controller
The reflected image being formed is left in internal memory c) on ccd video camera 23.It is then act through image procossing and carry out diode reflective figure
The determination of the position of centre of gravity of picture, and carry out the calculating of corneal radii by illustrated approximate formula in dd251497.For
Improve the reproducibility of measurement result, each measurement process is recorded with about 5 image sequence (by with and without by synchronization
Each two and half image compositions of the illumination of the led of beat).
vkt
This outer controller c is to be connected with diode 12.Similar in appearance to cornea instrument preferentially to hold in the process of regulation (correction)
Continuous light mode runs diode 12.
In measurement process selectively through controller make the light emitting diodes of left and right eyes are sent beat (similar in appearance to
Cornea instrument).To the left or move right instrument by the regulation of operator, and by ... by instrumental correction to eye center point.
Obtain the marginal position of dispersion image by image procossing.As already described, from cornea dispersion image and
Vkt is calculated in the distance of crystalline lenses dispersion image.About 5 image sequence are equally recorded to each measurement process.
Illumination
Controller c is to be connected with diode 12.At any time can be with via controller (in program inside or by operation
Member controls ground) access ir diode 24 for eye illumination.This outer controller be (not shown) with for inwardly or outwardly putting
Dynamic/adjust doe 9, lens 18,19,22 and controlling of aperture 21 connect.
Through land used storage adjustable in Instrument memory, common computing formula is from calculated measured value in the world
Carry out the calculating of iol in al, hhr, vkt, and print through printer.
Claims (6)
1. one kind is used for determining the device of the anterior chamber depth of eyes (14), has
A) via imaging microscope group, towards the incident slot-shaped illumination of eyes (14) on the downside of for an angle observing axle,
B) there is concatenation signal processing, collection is derived from the receiver apparatus of the dispersion image of eyes (14), and
C) controller (c) after described receiver apparatus.
2. device according to claim 1, wherein said slot-shaped illumination include light source and with illumination direction after light source cloth
The gap put.
3. device according to claim 2, wherein said light source is led.
4. device according to claim 1, wherein said slot-shaped illumination includes image forming optics and described image opticss
Device is the image forming optics of shifting ground construction.
5. device according to claim 1, wherein said slot-shaped illumination includes a series of white light led.
6. the device according to any one of claim 1 to 5, the receiver apparatus of this device are ccd video camera (23).
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19857001.5 | 1998-12-10 | ||
| DE19857000.7 | 1998-12-10 | ||
| DE1998157001 DE19857001A1 (en) | 1998-12-10 | 1998-12-10 | Non-contact method and device for measuring eye's length of axis, cornea's curvature and eye's main chamber depth assists selection of intra-ocular lenses to be implanted in eye |
| DE1998157000 DE19857000A1 (en) | 1998-12-10 | 1998-12-10 | Method and set-up for measuring and surveying partial eye sections, especially main chamber depth, includes split light beamed onto eye and CCD camera to record scatter images coming from eye through achromatic lens |
| CNB998143537A CN100502762C (en) | 1998-12-10 | 1999-12-10 | Combined instruments for non-contacting measurement of the axis length and cornea curvature of eye |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB998143537A Division CN100502762C (en) | 1998-12-10 | 1999-12-10 | Combined instruments for non-contacting measurement of the axis length and cornea curvature of eye |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101612033A CN101612033A (en) | 2009-12-30 |
| CN101612033B true CN101612033B (en) | 2017-01-18 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910140945.2A Expired - Lifetime CN101612033B (en) | 1998-12-10 | 1999-12-10 | A device for determining anterior chamber depth of an eye |
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| Country | Link |
|---|---|
| CN (1) | CN101612033B (en) |
| DE (1) | DE19857001A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10323920A1 (en) * | 2003-05-22 | 2004-12-16 | Carl Zeiss Meditec Ag | Method and arrangement for measuring the anterior segment of the eye |
| DE10349230A1 (en) * | 2003-10-23 | 2005-07-07 | Carl Zeiss Meditec Ag | Apparatus for interferometric eye length measurement with increased sensitivity |
| WO2005077256A1 (en) * | 2004-02-06 | 2005-08-25 | Optovue, Inc. | Optical apparatus and methods for performing eye examinations |
| CA2553761A1 (en) | 2004-02-10 | 2005-08-25 | Optovue, Inc. | High efficiency low coherence interferometry |
| ES2665536T3 (en) | 2004-04-20 | 2018-04-26 | Alcon Research, Ltd. | Integrated surgical microscope and wavefront sensor |
| DE102005026371B4 (en) | 2005-06-07 | 2024-02-08 | Oculus Optikgeräte GmbH | Method for operating an ophthalmological analysis system |
| DE102006054774A1 (en) | 2006-11-17 | 2008-05-21 | Carl Zeiss Meditec Ag | Ophthalmological examination device |
| DE102007017599A1 (en) | 2007-04-13 | 2008-10-16 | Carl Zeiss Meditec Ag | Apparatus and method for axial length measurement with extended measurement function in the anterior segment of the eye |
| US7594729B2 (en) | 2007-10-31 | 2009-09-29 | Wf Systems, Llc | Wavefront sensor |
| EP2364105B1 (en) | 2008-11-04 | 2018-03-14 | Carl Zeiss Meditec AG | Ophthalmological measuring system and method for calibrating and/or adjusting the same |
| DE102008055755A1 (en) | 2008-11-04 | 2010-05-06 | Carl Zeiss Meditec Ag | Ophthalmologic measurement system i.e. optical biometer, for obtaining biometric data of eyes of patient, has test unit i.e. test eye, with test eye receiving device for varying position of test unit with respect to evaluating unit |
| DE102009030467A1 (en) * | 2009-06-23 | 2011-01-05 | Carl Zeiss Meditec Ag | Device for recording high-dynamic fundus- and slit images of human eyes during e.g. examining cataract operations, has sensor-arrays comprising connections to evaluation unit, and beam splitter distributing light from eyes to sensor-arrays |
| CN104367299B (en) * | 2009-07-14 | 2017-09-15 | 波技术视觉系统公司 | Ophthalmic surgery measurement system |
| DE102009041996A1 (en) | 2009-09-18 | 2011-03-24 | Carl Zeiss Meditec Ag | Ophthalmic biometry or imaging system and method for acquiring and evaluating measurement data |
| DE102010047053A1 (en) * | 2010-09-29 | 2012-03-29 | Carl Zeiss Meditec Ag | Method and device for the interferometric determination of different biometric parameters of an eye |
| DE102010055350A1 (en) | 2010-12-20 | 2012-06-21 | Carl Zeiss Meditec Ag | Apparatus for the interferometric measurement of the eye length and the anterior eye portion |
| DE102011106898A1 (en) * | 2011-07-07 | 2013-01-10 | Jenoptik Optical Systems Gmbh | Ophthalmic procedure and associated ophthalmic device |
| DE102011082500A1 (en) * | 2011-08-26 | 2013-02-28 | Oculus Optikgeräte GmbH | Ophthalmological analyzer and method |
| CN103040436B (en) * | 2011-10-14 | 2016-01-06 | 上海美沃精密仪器有限公司 | One moves axle tomography eye scanning system |
| DE102012011880A1 (en) | 2012-01-18 | 2013-07-18 | Carl Zeiss Meditec Ag | Contactless measuring device for ophthalmic calculation and selection of intraocular lenses, has keratometer arrangement that is provided for determining corneal curvature of eye |
| US9072462B2 (en) | 2012-09-27 | 2015-07-07 | Wavetec Vision Systems, Inc. | Geometric optical power measurement device |
| DE102014207058A1 (en) | 2014-04-11 | 2015-10-15 | Carl Zeiss Meditec Ag | Method for measuring and reconstructing curved, reflecting surfaces |
| CN109222887A (en) * | 2018-08-30 | 2019-01-18 | 上海理工大学 | A kind of portable hand-held cornea curvimeter based on object space telecentric beam path |
| WO2022136192A1 (en) * | 2020-12-23 | 2022-06-30 | Essilor International | Method of evaluating the efficiency of a myopia control solution |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2047174U (en) * | 1989-02-18 | 1989-11-08 | 王凤民 | Measuring instrument for examining cornea thickness and atrial depth |
| US5563667A (en) * | 1993-10-29 | 1996-10-08 | Nidek Co., Ltd. | Opthalmic apparatus having lowered consumption of electric power |
| EP0776628A2 (en) * | 1995-10-31 | 1997-06-04 | Akitoshi Yoshida | Intraocular substance measuring apparatus |
| US5673096A (en) * | 1994-12-23 | 1997-09-30 | Carl Zeiss Jena Gmbh | Interferometric arrangement with diffractive optical element for measuring intraocular distances |
| US5784146A (en) * | 1995-12-28 | 1998-07-21 | Nidek Co., Ltd | Ophthalmic measurement apparatus |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4019813A (en) * | 1976-01-19 | 1977-04-26 | Baylor College Of Medicine | Optical apparatus for obtaining measurements of portions of the eye |
| US4572628A (en) * | 1981-05-29 | 1986-02-25 | Nippon Kogaku K.K. | Method of and apparatus for measuring radius |
| DE3201801A1 (en) * | 1982-01-21 | 1983-09-08 | Adolf Friedrich Prof. Dr.-Phys. 4300 Essen Fercher | Method and device for measuring the component sections of the living eye |
| JPS6057328A (en) * | 1983-09-07 | 1985-04-03 | Seiko Koki Kk | Automatic setting device of film sensitivity of camera |
| DD251491A1 (en) * | 1986-07-29 | 1987-11-18 | Fettchemie Abt Foe Sr Veb | EMULSIONS FOR FEEDING PURPOSES |
| US5042938A (en) * | 1989-05-09 | 1991-08-27 | Kabushiki Kaisha Topcon | Apparatus for measuring length of visual line length, depth of anterior chamber, thickness of crystal lens, etc. |
| JPH0779797B2 (en) * | 1989-07-28 | 1995-08-30 | キヤノン株式会社 | Keratometer |
| JP3042851B2 (en) * | 1990-01-29 | 2000-05-22 | 株式会社ニデック | Corneal shape measuring device |
| DE4210384A1 (en) * | 1992-03-30 | 1993-10-07 | Stiller Henning | Device and method for examining the eye |
| US5282852A (en) * | 1992-09-02 | 1994-02-01 | Alcon Surgical, Inc. | Method of calculating the required power of an intraocular lens |
| US5493109A (en) * | 1994-08-18 | 1996-02-20 | Carl Zeiss, Inc. | Optical coherence tomography assisted ophthalmologic surgical microscope |
-
1998
- 1998-12-10 DE DE1998157001 patent/DE19857001A1/en not_active Withdrawn
-
1999
- 1999-12-10 CN CN200910140945.2A patent/CN101612033B/en not_active Expired - Lifetime
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2047174U (en) * | 1989-02-18 | 1989-11-08 | 王凤民 | Measuring instrument for examining cornea thickness and atrial depth |
| US5563667A (en) * | 1993-10-29 | 1996-10-08 | Nidek Co., Ltd. | Opthalmic apparatus having lowered consumption of electric power |
| US5673096A (en) * | 1994-12-23 | 1997-09-30 | Carl Zeiss Jena Gmbh | Interferometric arrangement with diffractive optical element for measuring intraocular distances |
| EP0776628A2 (en) * | 1995-10-31 | 1997-06-04 | Akitoshi Yoshida | Intraocular substance measuring apparatus |
| US5784146A (en) * | 1995-12-28 | 1998-07-21 | Nidek Co., Ltd | Ophthalmic measurement apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101612033A (en) | 2009-12-30 |
| DE19857001A1 (en) | 2000-06-15 |
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