CN101611014B - 用作fgfr抑制剂的酰氨基吡唑类化合物 - Google Patents

用作fgfr抑制剂的酰氨基吡唑类化合物 Download PDF

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Publication number
CN101611014B
CN101611014B CN2007800516051A CN200780051605A CN101611014B CN 101611014 B CN101611014 B CN 101611014B CN 2007800516051 A CN2007800516051 A CN 2007800516051A CN 200780051605 A CN200780051605 A CN 200780051605A CN 101611014 B CN101611014 B CN 101611014B
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China
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pyrazole
dimethoxyphenyl
group
ethyl
alkyl
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Chinese (zh)
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CN101611014A (zh
Inventor
K·M·富特
M·-E·西奥克利托
A·P·汤玛斯
D·巴塔
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AstraZeneca AB
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AstraZeneca AB
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Priority claimed from PCT/GB2007/004917 external-priority patent/WO2008075068A2/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN2007800516051A 2006-12-21 2007-12-20 用作fgfr抑制剂的酰氨基吡唑类化合物 Active CN101611014B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US87119006P 2006-12-21 2006-12-21
US60/871,190 2006-12-21
US98554207P 2007-11-05 2007-11-05
US60/985,542 2007-11-05
PCT/GB2007/004917 WO2008075068A2 (en) 2006-12-21 2007-12-20 Acylaminopyrazoles as fgfr inhibitors

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CN101611014A CN101611014A (zh) 2009-12-23
CN101611014B true CN101611014B (zh) 2012-05-30

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CN (1) CN101611014B (xx)
AR (1) AR110227A2 (xx)
ES (1) ES2364864T3 (xx)
UA (1) UA96969C2 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102032007B1 (ko) 2012-02-28 2019-10-14 아스텔라스세이야쿠 가부시키가이샤 질소 함유 방향족 헤테로환 화합물
CN105601617B (zh) * 2016-03-24 2019-02-22 山东省科学院生物研究所 一种邻二氮杂环化合物及其制备方法与应用
CN107459519A (zh) * 2016-06-06 2017-12-12 上海艾力斯医药科技有限公司 稠合嘧啶哌啶环衍生物及其制备方法和应用
CN107840842A (zh) * 2016-09-19 2018-03-27 北京天诚医药科技有限公司 炔代杂环化合物、其制备方法及其在医药学上的应用
US11078194B2 (en) * 2017-12-07 2021-08-03 Harbin Zhenbao Pharmaceutical Co., Ltd. Salt form and crystal form serving as FGFR and VEGFR inhibitor compounds, and preparation method therefor
CN110317173B (zh) * 2018-03-30 2022-10-11 上海奕拓医药科技有限责任公司 用作fgfr不可逆抑制剂的酰胺基吡唑类化合物
CN114728910B (zh) * 2019-08-31 2024-05-14 上海奕拓医药科技有限责任公司 用于fgfr抑制剂的吡唑类衍生物及其制备方法
CN111072638B (zh) * 2019-12-13 2021-03-16 上海工程技术大学 一种制备azd4547的方法、中间体及中间体的制备方法
CN111253314B (zh) * 2020-03-16 2023-04-07 创沐医药科技(上海)有限公司 乙烯基磺酰胺基取代的吡唑基苯甲酰胺类化合物

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Publication number Publication date
CN101611014A (zh) 2009-12-23
UA96969C2 (xx) 2011-12-26
ES2364864T3 (es) 2011-09-15
AR110227A2 (es) 2019-03-06

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