CN101606862A

CN101606862A - The simple low-temperature operation device of ultrasonic or peritoneoscope treating in-vivo tumour under aid

Info

Publication number: CN101606862A
Application number: CNA2009100317788A
Authority: CN
Inventors: 郁如煌
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-07-14
Filing date: 2009-07-14
Publication date: 2009-12-23
Anticipated expiration: 2029-07-14
Also published as: CN101606862B

Abstract

The invention discloses a kind of easy to be hand-held cryosurgery system of ultrasonic or peritoneoscope treating in-vivo tumour under aid, it is characterized in that this device with in the puncture body under the ultrasonic guidance with seriation cryoprobe and peritoneoscope with two kinds of extended type cryoprobes, be installed in by flexible pipe have intelligent temperature control, transfusion control system, low-temperature solenoid valve are infused (nitrogen) conditioning function straight, utilize coffee pot to make liquid reservoir with on the hand-held microminiature main body; Break the world today and implemented puncture treatment in-vivo tumour cryosurgery under the ultrasonic guidance, must be with spending huge sums from the ultralow temperature cutter of the U.S., Germany, Israel's import or deifying of argon helium knife, with this extremely easy cryosurgery system, assist down at ultrasonic or peritoneoscope, can implement to be in now cryosurgery frontline technology, the non-cryosurgery of opening abdomen percutaneous puncture treatment in-vivo tumour equally.

Description

The simple low-temperature operation device of ultrasonic or peritoneoscope treating in-vivo tumour under aid

Technical field

The present invention relates to a kind of cryosurgery operating theater instruments of physiotherapy, it makes cold-producing medium with liquid nitrogen, ultrasonic guidance is punctured down with seriation cryoprobe or peritoneoscope extended type cryoprobe, be installed in by flexible pipe have intelligent temperature control, the transfusion control system, low-temperature solenoid valve infuse straight (nitrogen) function, select for use coffee pot to do on storage liquid (nitrogen) device, in the ultrasonic or auxiliary a kind of cryosurgery operating theater instruments of percutaneous puncture in treating in-vivo tumour down of peritoneoscope

Along with technological progress, last century Mo U.S. Cryomedical Sciences, Inc. (CMSI/SACC) at first researches and develops successful CMS and explores 450 (liquid nitrogen) cryosurgery system and be used for clinical, realized under the ultrasonic guidance that the non-abdomen of opening carries out the vision that cryosurgery is treated to deep layer tumor in the human body.State-owned only a few hospital spends more than 300 ten thousand RMB in over past ten years, introduced the steel cylinder argon of two each heavy 72Kg of usefulness of the production of U.S. CMS Germany Ai Erbo electronic medical equipment company, ERBE CRY0 6 ultralow temperature cuttves and U.S. Endocare company and the production of Israel GALI subsidiary, the argon helium knife that helium is made the refrigeration source of the gas, be used to explore the cryosurgery new technique application of percutaneous puncture minimally-invasive treatment in-vivo tumour under ultrasonic or the guided by magnetic resonance with the cabinet type liquid nitrogen cryotherapy device of flexible pipe classical architecture.The advanced medical apparatus of these two kinds of costlinesses " mystery ", and do not meet China's actual conditions, be difficult in China's popularization and come.

Publication number CN101396299A " the mutual Contiuum type cryosurgery system of Du that closes with the peritoneoscope Rhizoma Nelumbinis " propose first a kind of with the extended type cryoprobe by peritoneoscope puncture sheath pipe to deep layer tumor in the bodies such as kidney, liver, uterus, gastrointestinal, carry out the Dewar integrated low-temperature operation device of cryoablation operative treatment: the brief technical pattern that adopts Dewar to combine, close with the abdominal cavity Rhizoma Nelumbinis from supercharging discharge opeing and the heat insulation liquid nitrogen two-phase transmission technology of air film, directly use from supercharging discharge opeing Dewar flask and do apparatus main body (machine), with-196 ℃ of liquid nitrogen of single lucite pipe two-phase transmission; For opening, peritoneoscope is used for the new application function of cryosurgery operation.

Publication number CN101390774A " the seriation cryoprobe that is used for puncture for treating in-vivo tumour under the ultrasonic guidance " has diameter 2.6mm, 3.0mm and 12 kinds of three kinds of specifications of 3.5mm, be primarily characterized in that: because the ultra-fine cryoprobe of this series has adopted and the different project organization of ERBE CRYO 6 ultralow temperature cutter cryoprobes, and reduced the liquid nitrogen discharge pressure significantly, also reduced specification requirement thus to matched host machine, ultra-fine cryoprobe for this series, the intention of the main frame of the easy structure that the developing research and development match with it will come true.

Summary of the invention

Goal of the invention the objective of the invention is: at tumor cryosurgery in the puncture for treating body under world today's enforcement ultrasonic guidance, must be with spending huge sums from the U.S., Germany, the ultralow temperature cutter of Israel's import or the present situation of argon helium knife, from China's actual conditions, how solution adopts a kind of extremely easy cryosurgery system to replace costs an arm and a leg, the cabinet type liquid nitrogen cryotherapy device of baroque flexible pipe classical architecture problem? the seriation cryoprobe and the publication number CN101396299A peritoneoscope that are used for puncture for treating in-vivo tumour under the ultrasonic guidance for publication number CN101390774A provide a kind of simple in structure with two kinds of extended type cryoprobes, function is more complete, the microminiature main body (machine) that economical and practical usefulness is hand-held; Pioneering and inventing out does not have, has now the simple low-temperature operation device of the ultrasonic of Chinese technical characteristic or peritoneoscope treating in-vivo tumour under aid both at home and abroad.

Technical scheme realizes that technical scheme of the present invention is: a kind of with publication number CN101390774A seriation cryoprobe and two kinds of extended type cryoprobes of publication number CN1013396299A, be installed in by flexible pipe have intelligent temperature control, the transfusion control system, low-temperature solenoid valve infuse straight (nitrogen) function, select for use coffee pot to make the simple low-temperature operation device of a kind of ultrasonic or peritoneoscope treating in-vivo tumour under aid on storage liquid (nitrogen) device: it by with hand-held microminiature main body, flexible pipe, cryoprobe, organize thermometric needle, temperature actuated case to form; Its feature one is: microminiature main body 1 comprises coffee pot la kettle mouth 6O type silica gel circle 7 pot lids 8; The low-temperature solenoid valve fluid-delivery valve 11 that pot lid 8 central authorities install reaches micro-pressure gauge 9, adjust blood pressure atmospheric valve 10 and two regulator valves 29 to install in the cross equispaced screw around; Insert in the low-temperature solenoid valve fluid-delivery valve 11 lower end eyelets and be welded with red copper liquid nitrogen center outlet tube 2; Its feature two is: the rustless steel flexible pipe 12 that has hard seal ball head 12-1 and the active nut 12a of hexagonal, 12b by two ends is twisted and is connect with seriation cryoprobe 15a or two kinds of extended type cryoprobe 15b tail end screw terminals, low-temperature solenoid valve fluid-delivery valve 11 screw terminals suitable for reading respectively; Its feature three is: intelligent temperature control system by slugging at cryoprobe 15a (15b) the most advanced and sophisticated and temperature detector node 17 of organizing thermometric needle 16a (16b) needle point and pass that lead-in wire connection-

peg

17a and 17b, the corresponding socket 18a of temperature actuated case 28 backboards and 18b be communicated with, cryoprobe is with intelligent temperature controller 23 and organize thermometric temperature controller 24 and freezing time-delay timer 25 time set buttons 26 compositions; Its feature four is: transfusion control system silica gel tube 22, the aerofluxus on temperature actuated case 28 backboards of being drawn by cold nitrogen exhaust pipe 13 of cryoprobe 15a (15b) afterbody and socket is spigot joint 19, the miniature electromagnetic valve 20 in the intelligent temperature controller 23; Be installed on the coffee pot la handgrip 3 and form with power line grafting headstock 4 eletric buttons, 5 grafting clip 5a that draw from intelligent temperature control control box 28 backboards and low-temperature solenoid valve fluid-delivery valve 11; Its feature five is: disposed two in the device and be respectively applied for when ultrasonic guidance or peritoneoscope are auxiliary implements cryosurgery down, detect cryoprobe freeze behind the 15a (15b) the substrate of tumor focus edge organize

thermometric needle

16a and 16b.

Beneficial effect

1, the present invention has proposed a kind of simple low-temperature operation device that is used for ultrasonic or peritoneoscope treating in-vivo tumour under aid first: with ultra-fine cryoprobe 15a or two kinds of extended type cryoprobe 15b of seriation, be installed on the microminiature main body 1 of utilizing coffee pot la to make storage liquid (nitrogen) device by flexible pipe 12; Down auxiliary at ultrasonic guidance or peritoneoscope, can carry out equally and be in cryosurgery frontline technology technology now, the non-cryosurgery of opening abdomen percutaneous puncture in treating in-vivo tumour focus: implement puncture for treating in-vivo tumour cryosurgery under the ultrasonic guidance thereby broken the world today, must be with spending huge sums from the ultralow temperature cutter of the U.S., Germany, Israel's import and deifying of argon helium knife.

2, the ultra-fine cryoprobe 15a of seriation or two kinds of extended type cryoprobe 15b be installed in utilize small size vacuum coffee pot la to make the extremely easy technical pattern of microminiature main body 1, be continue publication number CNIO1396299A " the mutual Contiuum type cryosurgery system of Du that closes with the peritoneoscope Rhizoma Nelumbinis " cast out cost an arm and a leg, the heat insulation liquid nitrogen delivery hose of metal vacuum of complex manufacturing technology; Break away from huge heaviness, baroque landing after the rack main frame, broken to the great reality of another example of the cabinet type liquid nitrogen cryotherapy device of current flexible pipe classical architecture.

3, select for use the low-temperature solenoid valve 11 that uses on the spacecraft to be installed on coffee pot 1 pot lid 8, by manual eletric button 5 or control low-temperature solenoid valve 11 automatically by intelligent temperature controller 23 and infuse in (nitrogen) straight, agile reliable; Thereby the traditional infusion structure of the hand-held liquid nitrogen cryotherapy device since having made new advances ad initio.

4, utilize to conduct heat good aluminium alloy kettle mouth 6 pot lids 8 and extend into the red copper matter center tube for transfusion 2 in the liquid nitrogen in the coffee pot la, accelerate to adopt the evaporation rate of liquid nitrogen in the coffee pot la that seals the pressure accumulation banking system to increase external heat transfer, make interior liquid (nitrogen) face of coffee pot la can reach the above transfusion operating pressure of 100KPa fast.

5, micro-pressure gauge 9 and two regulator valves 29 of installing on the coffee pot la pot lid 8, be used for regulating the safe pressure value of two regulator valves 29 according to the variation of Pressure gauge 9 pointers, in case two adjust blood pressure safety 29 of superpressure just can rarely automatically be put the nitrogen in the coffee pot, to keep steady operation pressure within normal range, also play safe dual fail-safe effect simultaneously.

6, the performer of temperature control and transfusion control system is: be installed in coffee pot la pot lid 8 central low-temperature solenoid valve fluid-delivery valves 11 and be communicated with, be located at the interior miniature electromagnetic valve 20 of temperature actuated case 28 with the cold nitrogen exhaust pipe 13 of cryoprobe 15a (15b) afterbody; Be subjected to intelligent temperature controller 23 unified instruction opening and closing synchronously in pairs, end liquid nitrogen with moment and carry and cut off the mode that cold nitrogen is discharged gas circuit (being in no pressure reduction state), accurately regulate and control cryoprobe 15a (15b) tip temperature, with success and the effect that has ensured cryosurgery.

7,12 transition of employing flexible pipe connect low-temperature solenoid valve fluid-delivery valve 11 and the cryoprobe 15a (15b) on the coffee pot la, overcome the microminiature main body 1 that coffee pot la makes to store liquid (nitrogen) device, can not transition tilt and the difficulty of rotation adjustment of treatment angle, the cryoprobe of being convenient to puncture in the clinical operation is to the accurate location of tumor focus targeting.

8, utilize the eletric button 5 be installed on the coffee pot la handgrip 3, can independent manual low-temperature solenoid valve fluid-delivery valve 11, make hand-held microminiature main body 1 more flexible.

9, the power supply of low-temperature solenoid valve fluid-delivery valve 11, employing leads to power line grafting headstock 4 eletric buttons 5 on the coffee pot la handgrip 3 and the two-stage transition connected mode of grafting clip 5a from temperature actuated case 28 backboards, the all removable separation of all at ordinary times connection leads is convenient to pot lid 8 and adnexa thereof and is thrown off from coffee pot la.

10, in order to alleviate the weight of hand-held microminiature main body 1, the small size coffee pot la of elite usefulness makes storage liquid (nitrogen) device, and the gross weight that comprises all valves on the pot lid 8 is about 1000ml liquid nitrogen that 1Kg stored, and is enough to satisfy the liquid nitrogen consumption of a cryosurgery; The mobile working chassis 30 of configuration comes support fixation microminiature main body 1 except that being used to put the temperature actuated case 28 with lifting tray 30-5; Both alleviate the fatigue of the hand-held microminiature main body 1 of long period people, and can before clinical operation, regulate the suitable high and low position of microminiature main body 1 again; On mobile working chassis 30 lower shelf, configuration has been laid one and has been aimed at the spherical Dewar flask 30-1 of 10 supporting liter rustless steels of simple low-temperature operation device, and the liquid nitrogen among the forward and backward coffee pot la of convenient operation charges and receives together.

11, the simple low-temperature operation device of ultrasonic or peritoneoscope treating in-vivo tumour under aid provided by the invention, the processing ease wide application, estimate to research and develop the price of this " dual-use " cryosurgery apparatus product successfully, can be lower more than 1/150 than the price of import ERBE CRYO 6 ultralow temperature cuttves, general middle and small hospital can both be acquired.

Description of drawings

Accompanying drawing 1 is a simple low-temperature operation device structural representation

Wherein 1 microminiature main body la coffee pot, 2 centers transfusions (nitrogen) pipe, 3 handgrips, 4 power line grafting headstocks, 5 eletric buttons, 6 band screw kettle mouth 7O type silica gel circles 8 are with female thread pot lids 9 micro-pressure gauges 10 adjust blood pressure atmospheric valves 11 low-temperature solenoid valve fluid-delivery valves 12 flexible pipe 12a, the active nut 13 cold nitrogen exhaust pipe 14 liquid nitrogen spray pipe fixed handle 15a seriation cryoprobes 15 extended type cryoprobe 16a of 12 hexagonals, 16b organizes thermometric needle 17

temperature detector node

17a, 17b passes terminal pin 18a, the 22 cold nitrogen aerofluxuss of spigot joint 20 miniature electromagnetic valves of 18b intelligent temperature controller temperature detector socket 19 cold nitrogen aerofluxuss 21 external power supply patch are drawn silica gel tube 23 cryoprobes and are organized thermometric needle intelligent temperature controller 25 freezing time-delays timer 26 time set buttons 27 two-way self-locking electric switches 28 temperature actuated casees 29 regulator valves with intelligent temperature controller 24.

Accompanying drawing 2 is the structural representation of flexible pipe 12

Wherein the special silica gel protected pipe 14 of rustless steel waveform pipe 12-4 of the flexible tube head shroud ring of the active nut 12-2 of screw terminal 12-1 hard seal ball head 12a, 12b hexagonal 12-3 ￠ 2/4mm of 11-1 low-temperature solenoid valve fluid-delivery valve band awl endoporus is with the cryoprobe liquid nitrogen spray pipe connection handle of hexahedrons.

Accompanying drawing 3 is for organizing the structural representation of thermometric needle

Wherein the 16a ultrasound guided puncture is organized the auxiliary puncture down of thermometric needle 16b peritoneoscope to organize

thermometric needle

17a, 17b thermocouple to pass terminal pin 16-1 handle 16-2 ultrasound guided puncture to organize the auxiliary puncture of thermometric needle shank 16-3 sheath 1 16-4 peritoneoscope to organize thermometric needle needle handle 16-5 sheath 216-6 syringe needle 17 temperature detector nodes.

Accompanying drawing 4 is the structural representation of mobile working chassis

The spherical Dewar flask 30-2 of the 30 chassis 30-110 liter rustless steels tight screw 30-5 of the drawer 30-3 chassis handle 30-4 system lifting tray 30-6 tight loop 28 temperature actuated casees 1 microminiature main body of placing various standby cryoprobes wherein.

Below in conjunction with above-mentioned drawings and Examples the present invention is described

The specific embodiment

By accompanying drawing 1 as seen: realize the simple low-temperature operation device of ultrasonic or peritoneoscope treating in-vivo tumour under aid provided by the invention, with the ultra-fine cryoprobe of the seriation of publication number CN101390774A diameter 2.6mm.3.0mm and 12 kinds of three kinds of specifications of 3.5mm; Two kinds of extended type cryoprobes of publication number CN101396299A diameter 5mm, 10mm; Be installed in by flexible pipe and utilize coffee pot la to do on storage liquid (nitrogen) device, have intelligent temperature control, a transfusion control system, infuse the straight simple low-temperature operation device of a kind of ultrasonic or peritoneoscope treating in-vivo tumour under aid of (nitrogen) function of low-temperature solenoid valve; Form by microminiature main body 1 flexible pipe 12 cryoprobe 15a (15b) tissue thermometric needle 16a (16b) temperature actuated casees 28; Microminiature main body 1 comprises coffee pot la kettle mouth 6O type silica gel circle 7 pot lids 8; The low-temperature solenoid valve fluid-delivery valve of installing in the pot lid 8 central screws 11 reaches micro-pressure gauge 9 adjust blood pressure atmospheric valves 10 and two regulator valves 29 to install in the cross equispaced screw around; Insert in the low-temperature solenoid valve fluid-delivery valve 11 lower end eyelets and be welded with red copper matter liquid nitrogen center outlet tube 2; It is 1000ml that coffee pot la chooses capacity, be of a size of the small size vacuum coffee pot repacking of rustless steel of ￠ 140 * 170mm; For subtracting through weight, coffee pot la upper end is fixed with threaded kettle mouth 6 and the pot lid of handling with aluminum alloy materials processing and electrification 8, between seal to twist with the O type silica gel circle 7 that is filled with and connect; Low-temperature solenoid valve fluid-delivery valve 11 is selected the small-sized tubular through type low-temperature solenoid valve that uses on the spacecraft for use, and the screw terminal that contains 60 degree awl endoporus is equipped with at two ends; It is the Pressure gauge of 0-200KPa that micro-pressure gauge 9 is selected diameter 25mm range for use, adjust blood pressure atmospheric valve 10 is close to side by band screw mesopore, the threaded head in bottom and is made up of the pointed valve rod of venthole valve seat and band handle screw, adjust blood pressure atmospheric valve 10 is opened when flat, tighten during work or be used to finely tune pressure, " promptly " or do not work and turn on venting; Two regulator valve 29 structures and domestic pressure cooker relief valve are identical, in case the superpressure valve rod can be by the rare gas of spring jack-up; Coffee pot la kettle mouth 6 is close to side a screw, is used to install on the handgrip 3 of plastics compacting be equipped with and power line grafting headstock 4 eletric buttons 5 of drawing from intelligent temperature control control box 28 backboards and the grafting clip 5a of 11 two power supply wire-entering heads of low-temperature solenoid valve fluid-delivery valve.

By accompanying drawing 1,2 as seen: cryoprobe among the present invention adopts is the ultra-fine cryoprobe 15a of the seriation that provides of publication number CN101390774A and two kinds of extended type cryoprobe 15b that publication number CN101396299A provides; For the ease of assembling or dismounting, special liquid nitrogen spray pipe connection handle 14 rear ends with former cryoprobe 15a (15b) afterbody change and are processed into the screw terminal that the band hexahedron contains 60 degree awl endoporus; Flexible pipe 12 usefulness are of a size of the special rustless steel waveform pipe 12-3 of ￠ 2/4mm and make, overcoat silica gel tube 12-4 protection, length 280mm; Flexible pipe 12 two ends are welded with hard seal ball head 12-11 and the active nut 12a of hexagonal, 12b and twist and connect with seriation cryoprobe 15a or extended type cryoprobe 15b tail end screw terminal, low-temperature solenoid valve fluid-delivery valve 11 screw terminals suitable for reading respectively; The long rustless steel flexible pipe 12 of 280mm had around property, can satisfy in the clinical operation adjustment of treatment angle and puncture cryoprobe 15a (15b) to the accurate location of tumor focus targeting.

By accompanying drawing 1 as seen: intelligent temperature control system is most advanced and sophisticated and organize the temperature detector node 17 of thermometric needle 16a (16b) needle point and pass lead-in wire connection-

peg

17a and 17b at cryoprobe 15a (15b) by slugging, with be communicated with from the corresponding socket 18a of temperature actuated case 28 backboards and 18b, cryoprobe is with intelligent temperature controller 23 and knit thermometric needle freezes time-delay with intelligent temperature controller 24, cooling timer 25 time set buttons 26 compositions; Timer 25 and time are set button 26 and adopt 4 LCD digital displays to preset the structure of countdowning, be provided with 1 second, 10 seconds, 1 minute, 10 minutes four by strong, can be provided with arbitrarily in the scope at 1 second to 99 minutes; Temperature detector is selected copper, the copper-constantan thermocouple of T calibration for use, intelligent temperature controller 23,24 preferred dimensions are 96 * 48 * 82mm (horizontal stroke) MT61X series intelligent PID temperature controller, have the output of No. two relays, can realize that two limits are reported to the police or three-position type is controlled, strong self-setting function adapts to controlled object automatically; Spigot joint 19 intelligent temperature controllers of aerofluxus 23 miniature electromagnetic valves 20 on silica gel tube 22 temperature actuated casees 28 backboards that the transfusion control system is drawn by cold nitrogen exhaust pipe 13 of cryoprobe 15a (15b) afterbody and socket; Be installed on the coffee pot la handgrip 3, form from power line grafting headstock 4 eletric buttons, 5 patch clip 5a and low-temperature solenoid valve fluid-delivery valve 11 that temperature actuated case 28 backboards are drawn; Miniature electromagnetic valve 2 selects for use the miniature electromagnetic valve on the sphygomanometer to convert.

By accompanying drawing 3 as seen: disposed in the device two be respectively applied under ultrasonic guidance or the auxiliary cryosurgery down of peritoneoscope in, that detects tumor focus edge substrate after cryoprobe 15a (15b) freezes organizes

thermometric needle

16a and 16b, passes

terminal pin

17a, 17b by thermocouple respectively; Handle 16-1 shank 16-2 sheath 116-3 needle handle 16-4 sheath 216-5 syringe needle 16-6 temperature detector node 17 is formed; Thermometric needle 16b needle handle 6-4 makes of the 5mm stainless steel tube, is used for being inserted into in-vivo tumour lesion tissue edge by the puncture of peritoneoscope 5mm sheath pipe when the auxiliary enforcement down of peritoneoscope cryosurgery; Organize thermometric needle 16a shank length consistent, organize thermometric needle 16b needle handle, syringe needle total length consistent with extended type cryoprobe 15b shank length with seriation cryoprobe 15a shank length.

By accompanying drawing 4 as seen: the mobile working chassis is deposited the tight screw 30-4 of drawer 30-2 chassis handle 30-3 system lifting tray 30-5 tight loop 30-6 by chassis 30 various standby cryoprobes and is formed; Two standpipes that lifting tray 30-5 installs by a side lower part are inserted into chassis 30 platens and protect and block in two column jeckets in the place ahead, be used for height up and down and fix with making tight screw 30-4; Temperature actuated case 28 is placed on the platen, and it is fixing that microminiature main body 1 is put into the intermediary tight loop 30-6 of lifting tray 30-5, and pallet 30-5 can extract the support that clubhauls out from protecting to block the column jecket at ordinary times; Perform the operation for convenience the charging and reclaiming of liquid nitrogen among the forward and backward coffee pot la, the spy has disposed one the 10 spherical Dewar flask 30-1 of liter high vacuum insulation rustless steel, is placed on mobile working chassis 30 lower shelf.

In tumor focus targeting cryosurgery process, two groups of the red greens of intelligent temperature controller 23,24 temperature shows the flicker that charactrons did not stop along with the time, show the freezing tip of cryoprobe 15a (15b) respectively and thrust tumor focus edge substrate tissue thermometric needle 16a (16b) needle point desired temperature and the temperature change value that reaches is fallen when freezing.When the freezing tip of cryoprobe 15a (15b) falls when reaching the treatment temperature value that presets, intelligent temperature controller 23 sends instruction and closes low-temperature solenoid valve 11 and 20 moments of miniature electromagnetic valve and end liquid nitrogen synchronously and carry and cut off cold nitrogen and discharge gas circuit and stop refrigeration; After freezing tip temperature rose, intelligent temperature controller 23 can send instruction again and open temperature control electromagnetic valve 11 and miniature electromagnetic valve 20 continuation transfusion refrigeration; When falling, tumor focus targeting edge substrate tissue temperature reaches when presetting the downright bad temperature of histiocyte (50 ℃), being contained in intelligent temperature controller 24 on the temperature actuated case 28 can send instruction and make buzzer call, just can close temperature actuated case 28 power supplys after a few minutes, open adjust blood pressure atmospheric valve 10 exhaust pressure reliefs; Treat freezing tip and freezing after the thawing of tumor focus target tissue nature throw off after, can and organize thermometric needle 16a (16b) to extract out with cryoprobe 15a (15b), the freezing procedures of end cryosurgery.

Claims

1. one kind with publication number CN101390774A seriation cryoprobe and two kinds of extended type cryoprobes of publication number CN101396299A, be installed in by flexible pipe have intelligent temperature control, the transfusion control system, low-temperature solenoid valve infuse straight (nitrogen) function, select for use coffee pot to make the simple low-temperature operation device of a kind of ultrasonic or peritoneoscope treating in-vivo tumour under aid on storage liquid (nitrogen) device: it by with hand-held microminiature main body, flexible pipe, cryoprobe, organize thermometric needle, temperature actuated case to form; It is characterized in that: microminiature main body (1) comprises coffee pot (1a) Hu Kou (6) O type silica gel circle (7) pot lid (8); The low-temperature solenoid valve fluid-delivery valve (11) that pot lid (8) central authorities install reaches micro-pressure gauge (9) adjust blood pressure atmospheric valve (10) and two regulator valves (29) to install in the cross equispaced screw around; Insert in the eyelet of low-temperature solenoid valve fluid-delivery valve (11) lower end and be welded with red copper matter liquid nitrogen center outlet tube (2); Have hard seal ball head (12-1) and the active nut of hexagonal (12a) rustless steel flexible pipe (12) (12b) by two ends, twist and connect with the ultra-fine cryoprobe (15a) of seriation or two kinds of extended type cryoprobes (15b) tail end screw terminal, low-temperature solenoid valve fluid-delivery valve (11) screw terminal suitable for reading respectively; Intelligent temperature control system by slugging cryoprobe (15a) (15b) most advanced and sophisticated and organize thermometric needle (16a) (16b) needle point temperature detector node (17) and pass lead-in wire connection-peg (17a) and (17b), the corresponding socket of temperature actuated case (28) backboard (18a) and (18b) being communicated with, cryoprobe is with intelligent temperature controller (23) and knit thermometric needle and form with intelligent temperature controller (24) and freezing time-delay usefulness timer (25) time set button (26); The transfusion control system is by (15b) miniature electromagnetic valve 20 in spigot joint 19, the intelligent temperature controller 23 of the cold nitrogen exhaust pipe of afterbody (13) and the socket silica gel tube (22) of drawing, aerofluxus on temperature actuated case 28 backboards of cryoprobe (15a); Being installed in coffee pot (1a) handgrip (3) goes up and power line grafting headstock (4) eletric button (5) grafting clip (5a) of drawing from intelligent temperature control control box (28) backboard and low-temperature solenoid valve fluid-delivery valve (11) composition; Disposed two in the device and be respectively applied in that ultrasonic guidance or peritoneoscope are auxiliary when implementing cryosurgery down, that detects tumor focus edge substrate after cryoprobe freezes organizes thermometric needle (16a) and (16b).

2, the simple low-temperature operation device of the described ultrasonic or peritoneoscope treating in-vivo tumour under aid of claim 1; It is characterized in that real classical architecture of having broken the cabinet type liquid nitrogen cryotherapy device of flexible pipe, adopted the ultra-fine cryoprobe 15a of seriation and two kinds of extended type cryoprobe 15b, be installed in by flexible pipe 13 have intelligent temperature control, the transfusion control system, adopt low-temperature solenoid valve 11 directly infuse (nitrogen) function, utilize small size vacuum coffee pot to make extremely simply technical pattern on the microminiature main body of liquid reservoir.

3, the simple low-temperature operation device of claim 1,2 described ultrasonic or peritoneoscope treating in-vivo tumour under aid; Adopt low-temperature solenoid valve fluid-delivery valve 11 and cryoprobe 15a (15b) on the flexible pipe 13 transition connection coffee pot 1a, overcome the hand-held microminiature main body 1 of usefulness that coffee pot 1a makes to store liquid (nitrogen) device, can not transition tilt and the difficulty of rotation adjustment of treatment angle, be convenient in the clinical operation puncture cryoprobe the accurate location of tumor focus targeting.

4, the simple low-temperature operation device of the described ultrasonic or peritoneoscope treating in-vivo tumour under aid of claim 1; It is characterized in that utilizing good aluminium alloy kettle mouth 5 of conduction of heat and pot lid 7 and coffee pot 1a to extend into the red copper matter center tube for transfusion 2 among the liquid nitrogen in the coffee pot 1a, accelerate to adopt liquid nitrogen vaporization speed in the coffee pot 1a that seals the pressure accumulation banking system to increase external heat transfer, make the interior liquid nitrogen surface of coffee pot can reach the above operating pressure of 100KPa fast.

5, the simple low-temperature operation device of the described ultrasonic or peritoneoscope treating in-vivo tumour under aid of claim 1; The performer of intelligent temperature control and transfusion control system is: be installed in coffee pot 1a pot lid 8 central low-temperature solenoid valve fluid-delivery valves 11 and be communicated with, be located at the interior miniature electromagnetic valve 20 of temperature actuated case 28 with the cold nitrogen exhaust pipe 13 of cryoprobe 15a (15b) afterbody; Be subjected to intelligent temperature controller 23 unified instruction opening and closing synchronously in pairs, end liquid nitrogen with moment and carry and cut off the mode that cold nitrogen is discharged gas circuit (being in no pressure reduction state), accurately regulate and control cryoprobe 15a (15b) tip temperature, ensured the success and the effect of cryosurgery.