CN101601770A - A kind of Chinese medicine for the treatment of arthralgia, lumbago and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of Chinese medicine for the treatment of arthralgia, lumbago and preparation method thereof.Its constitutive material comprises Radix Rehmanniae, the Radix Angelicae Dahuricae, Rhizoma Atractylodis Macrocephalae (parched), Herba speranskiae tuberculatae, Radix Cyathulae, Herba Taxilli, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Drynariae, Fructus Corni, Radix Angelicae Pubescentis, Herba Asari totally ten two flavor Chinese crude drugs, the effect that its full side plays liver-kidney tonifying, expelling wind and cold, numbness relieving and pain relieving altogether has special efficacy for treatment arthralgia, lumbago.

Description

A kind of Chinese medicine for the treatment of arthralgia, lumbago and preparation method thereof

Technical field

The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of Chinese medicine for the treatment of arthralgia, lumbago and preparation method thereof.

Technical background

Lumbago is to be a kind of disease of cardinal symptom with waist one or both sides pain.The kidney disease of doctor trained in Western medicine, rheumatism, lumbar muscle strain, vertebra and diseases of spinal cord etc. are lumbago caused, and lumbago is one of total clinical manifestation of tens kinds of diseases.The weight of the head of human body, neck, two upper limb and trunk is all born by waist, and the attitude that daily life, worker mediate, heavy burden, motion all are the center with the waist.Waist is again the maincenter area that connects thoracic cavity, abdominal cavity, pelvic cavity.Therefore, lumbago can be the tissue in these structures, the performance of organ pathological change.In addition, disease of spinal column, waist muscle, ligament, neural disease and abdominal visceral browser etc. also all can show lumbago.

Prescriptions Worth Thousand Gold for Emergencies is rolled up 59 " lumbagos the 7th ": " all lumbagos have and say few the moon at five: one, and few cloudy kidney also.October, all things on earth yang-energy all declined, and was with lumbago.Two say the wind spleen, and wind and cold waist, are with lumbago.Three say and suffer from a deficiency of the kidney, and labour is with lumbago with being impairment of the kidney.Four say and waist, and the trauma due to falling down waist is with lumbago.Five say with getting cold dormancy, hindered by ground vapour, and be with lumbago.Pain is ended down, draws and leads spinal column, all pain ".Lumbago can be because of experiencing cold-damp, damp and hot, or the tumbling down wound, qi depression to blood stasis, or due to the deficiency of the kidney body void.It is basis that its pathological change often shows to suffer from a deficiency of the kidney, being invaded by exogenous pathogen, and the tumbling down sprain and contusion are the target characteristics.Face card and at first should differentiate the exterior and the interior deficiency and excess cold and heat.On the whole person due to the being invaded by exogenous pathogen, its card tables, true that belong to more, morbidity is rapid anxious, controls suitable eliminating evil collateral dredging, according to cold-damp, damp and hot difference, executes respectively and controls.By person due to the deficiency of the kidney, its card belong in, belong to empty, common chronic outbreak repeatedly, controlling to tonify Qi of the kidney is main.

The reason that causes lumbago diseases is a lot, have tens of kinds approximately, more common have waist hyperosteogeny, bony spur, intervertebral disc prolapse, hyperosteogeny, spinal canal stenosis, waist fracture, tumor in vertebral canal, waist acute and chronic wound or strain, lumbar muscle strain, an ankylosing spondylitis etc.In traditional view, the chronic back pain after disease factor is got rid of in general inspection is often regarded " lumbar muscle strain ", and in fact, what 4 one-tenth lumbago persons' trouble were arranged is chronic OFCS, but perplexed by lumbago owing to can not get symptomatic treatment.Many patients have the lumbago of long period, and people even pain have been arranged, and what also not to be known in 50 years sick.The trend that becomes younger of lumbago also clearly, the somebody just suffered from this disease in 18 years old.Lower back is human body maximum position of exerting oneself; for human body provides support and protects spinal column; to the people who lacks exercise in office's sitting for a long time; or because the people that job demand is stood for a long time; it is too of a specified duration to keep a position or posture for a long time; just cause the pain of lower back easily and cause the chronic OFCS of lumbosacral region, also have plenty of accumulation morbidity after repeated injury.A lot of chronic back pain patients are relevant with chronic OFCS, and may to be that iliacus is intermembranous cause every intrinsic pressure rising that the gap disappears under the fascia thoracolumbalis to reason, and the muscle blood flow descends, the fatty tissue degeneration of loosening.Because this infringement, caused no matter the patient is to walk more, sit more or drowsiness, all can pain in the lumbar region, promptly keep a kind of posture to be easy to generate pain in the lumbar region for a long time.This is the important clinical feature of chronic OFCS.

" disease " of the traditional Chinese medical science is meant that under the effect of the cause of disease the evil quadrature of body is striven, imbalance of YIN and YANG, and the evolution process that occurs with certain law of development, and concrete manifestation goes out the some specific symptoms and the corresponding syndrome in each stage.Every disease all has essence and rule separately, has promptly that certain cause of disease can be looked into, pathogenesis can be studied carefully, rule can be followed, method of treatment can survey according to, prognosis.Traditional Chinese medical science differential diagnosis of diseases is exactly kind and a name of disease of determining disease, promptly according to the collected clinical data of methods such as the four diagnostic methods, under instruction of Chinese Medicine theory, carry out analysis-by-synthesis, definition according to the traditional Chinese medical science " disease ", determine the disease kind of disease, and, be called " diagnosing a disease " again to the diagnosis thinking process that the characteristics and the rule of this disease kind are carried out globality.Lumbago is not a kind of disease, but one group of syndrome can be caused by multiple reason.Lumbago is a frequently-occurring disease, and normal and skelalgia exists simultaneously, and incidence rate is higher in physical labourer.Mention repeatedly in the argumentation of lumbago that in traditional Chinese medical science books clinical Chinese traditional medical diagnose lumbago has a lot of methods.Make lumbago sx or alleviation easier, but thoroughly cure difficulty, custom is sayed and is claimed " patient's lumbago, doctor's headache ".So the understanding of lumbago is known clearly in dialectical,, even, make name of disease ambiguous with card generation disease slightly in differential diagnosis of diseases, can not its overall situation of fine assurance.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicine for the treatment of arthralgia, lumbago and preparation method thereof.

Be achieved through the following technical solutions order of the present invention:

1, the present invention is the Chinese medicine of being made by the following weight proportion raw material:

Radix Rehmanniae 31-59 part Radix Angelicae Dahuricae 55-95 part Rhizoma Atractylodis Macrocephalae (parched) 40-80 part

Herba speranskiae tuberculatae 55-95 part Radix Cyathulae 31-59 part Herba Taxilli 55-95 part

Flos Carthami 40-80 part Rhizoma Chuanxiong 31-59 part Rhizoma Drynariae 40-80 part

Fructus Corni 31-59 part Radix Angelicae Pubescentis 40-80 part Herba Asari 40-80 part

2, best each the raw material weight proportioning of prescription of the present invention is:

70 parts of 81 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 49 parts of Radixs Angelicae Dahuricae of Radix Rehmanniae

81 parts of 49 parts of Herba Taxilli of 81 portions of Radix Cyathulaes of Herba speranskiae tuberculatae

70 parts of 49 parts of Rhizoma Drynariae of 70 parts of Rhizoma Chuanxiongs of Flos Carthami

70 parts of 70 parts of Herba Asaris of 49 parts of Radix Angelicae Pubescentiss of Fructus Corni

3, preparation method:

(1) gets all medicines and mix, add the water of 6～10 times of medical material amounts, decoct four times, decocted 1 hour at every turn;

(2) merge above-mentioned four decocting liquid, gradation filters, and the filtrate transpiring moisture is to an amount of;

(3) concentrated solution is put coldly, adds ethanol and fully stirs to make and contain alcohol amount and reach 50%, leaves standstill 24 hours;

(4) get supernatant, decompression recycling ethanol, and being condensed into 75 ℃ of heat, to survey relative densities be 1.38～1.46 thick paste, drying is ground into fine powder, adds appropriate amount of starch and cane sugar powder mixing, makes granule with suitable wetting agent, makes tablet, granule and capsule.

The invention discloses a kind of Chinese medicine for the treatment of arthralgia, lumbago and preparation method thereof.Its constitutive material comprises Radix Rehmanniae, the Radix Angelicae Dahuricae, Rhizoma Atractylodis Macrocephalae (parched), Herba speranskiae tuberculatae, Radix Cyathulae, Herba Taxilli, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Drynariae, Fructus Corni, Radix Angelicae Pubescentis, Herba Asari totally ten two flavor Chinese crude drugs, the effect that its full side plays liver-kidney tonifying, expelling wind and cold, numbness relieving and pain relieving altogether has special efficacy for treatment arthralgia, lumbago.

The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.

The specific embodiment

Embodiment 1: tablet

[prescription]

Radix Rehmanniae 49g Radix Angelicae Dahuricae 81g Rhizoma Atractylodis Macrocephalae (parched) 70g

Herba speranskiae tuberculatae 81g Radix Cyathulae 49g Herba Taxilli 81g

Flos Carthami 70g Rhizoma Chuanxiong 49g Rhizoma Drynariae 70g

Fructus Corni 49g Radix Angelicae Pubescentis 70g Herba Asari 70g

[preparation method]

(1) gets all medicines and mix, add the water of 8 times of medical material amounts, decoct four times, decocted 1 hour at every turn;

(2) merge above-mentioned four decocting liquid, gradation filters, and the filtrate transpiring moisture is to 300ml;

(3) concentrated solution is put coldly, adds ethanol and fully stirs to make and contain alcohol amount and reach 50%, leaves standstill 24 hours;

(4) get supernatant, decompression recycling ethanol, and being condensed into 75 ℃ of heat, to survey relative densities be 1.42 thick paste, and drying is ground into fine powder, adds the about 136g of starch, the about 15g of magnesium stearate, and mixing is used 60% alcohol granulation, drying, tabletting, promptly.

Embodiment 2: granule

[prescription]

Radix Rehmanniae 59g Radix Angelicae Dahuricae 95g Rhizoma Atractylodis Macrocephalae (parched) 80g

Herba speranskiae tuberculatae 95g Radix Cyathulae 59g Herba Taxilli 95g

Flos Carthami 80g Rhizoma Chuanxiong 59g Rhizoma Drynariae 80g

Fructus Corni 59g Radix Angelicae Pubescentis 80g Herba Asari 80g

[preparation method]

(1) gets all medicines and mix, add the water of 10 times of medical material amounts, decoct four times, decocted 1 hour at every turn;

(2) merge above-mentioned four decocting liquid, gradation filters, and the filtrate transpiring moisture is to 500ml;

(3) concentrated solution is put coldly, adds ethanol and fully stirs to make and contain alcohol amount and reach 50%, leaves standstill 24 hours;

(4) get supernatant, decompression recycling ethanol, and being condensed into 75 ℃ of heat, to survey relative densities be 1.39 thick paste, and drying is ground into fine powder, adds the about 75g of cane sugar powder, and mixing is used 80% alcohol granulation, and drying is sieved, and promptly gets granule.

Embodiment 3: capsule

[prescription]

Radix Rehmanniae 31g Radix Angelicae Dahuricae 55g Rhizoma Atractylodis Macrocephalae (parched) 40g

Herba speranskiae tuberculatae 55g Radix Cyathulae 31g Herba Taxilli 55g

Flos Carthami 40g Rhizoma Chuanxiong 31g Rhizoma Drynariae 40g

Fructus Corni 31g Radix Angelicae Pubescentis 40g Herba Asari 40g

[preparation method]

(1) gets all medicines and mix, add the water of 6 times of medical material amounts, decoct four times, decocted 1 hour at every turn;

(2) merge above-mentioned four decocting liquid, gradation filters, and the filtrate transpiring moisture is to 200ml;

(3) concentrated solution is put coldly, adds ethanol and fully stirs to make and contain alcohol amount and reach 50%, leaves standstill 24 hours;

(4) get supernatant, decompression recycling ethanol, and being condensed into 75 ℃ of heat, to survey relative densities be 1.44 thick paste, and drying is ground into fine powder, adds the about 88g of appropriate amount of starch, the about 14g of Pulvis Talci, and mix homogeneously, encapsulated, promptly get capsule.

Claims (3)

1, a kind of Chinese medicine for the treatment of arthralgia, lumbago is characterized in that it comprises what unit of weight was made by the following raw material of part:

Radix Rehmanniae 31-59 part Radix Angelicae Dahuricae 55-95 part Rhizoma Atractylodis Macrocephalae (parched) 40-80 part

Herba speranskiae tuberculatae 55-95 part Radix Cyathulae 31-59 part Herba Taxilli 55-95 part

Flos Carthami 40-80 part Rhizoma Chuanxiong 31-59 part Rhizoma Drynariae 40-80 part

Fructus Corni 31-59 part Radix Angelicae Pubescentis 40-80 part Herba Asari 40-80 part

2, a kind of Chinese medicine for the treatment of arthralgia, lumbago as claimed in claim 1 is characterized in that the weight proportion of each component is:

70 parts of 81 parts of Rhizoma Atractylodis Macrocephalae (parched)s of 49 parts of Radixs Angelicae Dahuricae of Radix Rehmanniae

81 parts of 49 parts of Herba Taxilli of 81 portions of Radix Cyathulaes of Herba speranskiae tuberculatae

70 parts of 49 parts of Rhizoma Drynariae of 70 parts of Rhizoma Chuanxiongs of Flos Carthami

70 parts of 70 parts of Herba Asaris of 49 parts of Radix Angelicae Pubescentiss of Fructus Corni

3, as the described a kind of Chinese medicine for the treatment of arthralgia, lumbago of claim 1-2, it is characterized in that this preparation method of Chinese medicine is:

(1) gets all medicines and mix, add the water of 6～10 times of medical material amounts, decoct four times, decocted 1 hour at every turn;

(2) merge above-mentioned four decocting liquid, gradation filters, and the filtrate transpiring moisture is to an amount of;

(3) concentrated solution is put coldly, adds ethanol and fully stirs to make and contain alcohol amount and reach 50%, leaves standstill 24 hours;

(4) get supernatant, decompression recycling ethanol, and being condensed into 75 ℃ of heat, to survey relative densities be 1.38～1.46 thick paste, drying is ground into fine powder, adds appropriate amount of starch and cane sugar powder mixing, makes granule with suitable wetting agent, makes tablet, granule and capsule.