CN101596334A - A kind of spliced prefilled injector and using method thereof - Google Patents
A kind of spliced prefilled injector and using method thereof Download PDFInfo
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- CN101596334A CN101596334A CNA2009100533363A CN200910053336A CN101596334A CN 101596334 A CN101596334 A CN 101596334A CN A2009100533363 A CNA2009100533363 A CN A2009100533363A CN 200910053336 A CN200910053336 A CN 200910053336A CN 101596334 A CN101596334 A CN 101596334A
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- syringe
- syringe needle
- ampoule
- sealing member
- spliced
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Abstract
The invention discloses a kind of spliced prefilled injector and using method thereof, comprise syringe, push the interior push rod of syringe, be connected in the syringe needle of syringe head and be placed in the outer pin medicated cap of syringe needle, also comprise one be arranged in the syringe, the ampoule that is filled with medicinal liquid in advance between syringe needle and push rod, the two ends of this ampoule are respectively by sealing member sealing, and the sealing member that wherein has an end at least is a plug that can move along the ampoule inwall; Method comprises: at first, and with the dismountable syringe head that is connected in of syringe needle; Then, syringe is put into by the ampoule of sealing member sealing respectively in that be filled with medicinal liquid in advance and two ends with one; At last push rod being promoted sealing member injects.The present invention adopts split-type structural, overcome integral type Pre-filled syringe in the prior art owing to the syringe needle long period of soaking in the needle tubing produces the contamination of heavy of heavy metal ion in medicinal liquid, it has various medicines convenient to use, safe, suitable, pharmaceutical quantities advantage accurately.
Description
Technical field
The present invention relates to a kind of syringe, relate in particular to a kind of spliced prefilled injector and using method thereof.
Technical background
In the prior art, injector for medical purpose is divided into the three generations haply from form:
First generation syringe is full glass manufacturing, repeatedly uses in hospital, and steaming and decocting is repeatedly used not only dangerous but also inconvenient, but with low cost;
Second filial generation syringe is exactly the plastic injector for temporary use that generally uses at present, and its shortcoming is to be easy to generate cross infection, and the costly medicine residual quantity is big;
Third generation syringe, be disposable Pre-filled glass or plastic injector and injection pen, this third generation syringe is an integral type Pre-filled syringe, it be with the direct fill of injectable drug in syringe, direct injection during use, the price of packaging material is higher, at present can provide the manufacturer of Pre-filled syringe filling apparatus few to the pharmaceutical factory in the world, and because manufactured materials and fill efficiency, the production cost of integral type Pre-filled syringe is high always, and the mortality defective of this integral type Pre-filled syringe is to have the contamination of heavy that produces heavy metal ion owing to the syringe needle long period of soaking in the needle tubing in medicinal liquid.
The method of traditional medicine injection has been continued to use many decades in China, and traditional in brief injectable drug mainly is divided into two kinds of forms:
1, aqueous injection: the packing of aqueous injection almost all with ampoule bottle packing, need be cut the glass ampule cervical region during use, in asepsis injector of resorb, gives patient injection or adds in the infusion bottle quiet, intramuscular injection etc.
2, injectable powder or lyophilized injectable powder: the manner of packing of injectable powder or lyophilized injectable powder all is separated into two parts basically: solvent with ampoule bottle or cillin bottle packing, solute with mold-formed bottle or glass tube vial packing.
Must be through five road programs during use: the solvent bottle of getting the ampoule packing earlier, cut (or breaking into pieces) its cervical region, again medicinal liquid sucked asepsis injector, a syringe needle and puncture the solute bottle plug, solvent is injected wherein, water and powder in the mixing solute bottle, once more mixing liquid sucked asepsis injector in the solute bottle, puncture infusion bottle and add medicinal liquid for quiet or intramuscular injection, quiet notes.
The drawback of tradition injecting method is apparent, and complex operation is hindered hands easily, and solvent repeatedly uses the probability that causes secondary pollution to increase, and valuable medicine remains in the medicine bottle etc. easily.
Summary of the invention
The objective of the invention is to overcome the defective of prior art, and provide a kind of spliced prefilled injector and using method thereof, it is a kind of syringe of injection medicament Pre-filled, adopt split-type structural, overcome integral type Pre-filled syringe in the prior art owing to the syringe needle long period of soaking in the needle tubing produces the contamination of heavy of heavy metal ion in medicinal liquid, it has various medicines convenient to use, safe, suitable, pharmaceutical quantities advantage accurately.
The technical scheme that realizes above-mentioned purpose is:
A kind of spliced prefilled injector of one of the present invention, comprise syringe, push the interior push rod of syringe, be connected in the syringe needle of syringe head and be placed in the outer pin medicated cap of syringe needle, wherein, also comprise one be arranged in the described syringe, the ampoule that is filled with medicinal liquid in advance between syringe needle and described push rod, the two ends of this ampoule are respectively by sealing member sealing, and the sealing member that wherein has an end at least is a plug that can move along the ampoule inwall.
Above-mentioned spliced prefilled injector, wherein, described ampoule adopts cyclic polyolefin to make.
Above-mentioned spliced prefilled injector, wherein, described plug adopts the medical grade butyl rubber to make.
Above-mentioned spliced prefilled injector, wherein, described syringe needle is detachable syringe needle.
Above-mentioned spliced prefilled injector, wherein, described syringe needle is connected with described syringe head by a syringe needle holder, the middle part of described syringe needle is passed this syringe needle holder and is fixed with it, have screw thread or draw-in groove on the described syringe needle holder, its dismountable head that is connected in described syringe.
The using method of a kind of spliced prefilled injector of two of the present invention, syringe comprise syringe, push push rod in the syringe, be connected in the syringe needle of syringe head and be placed in the outer pin medicated cap of syringe needle, and wherein, using method may further comprise the steps:
At first, with syringe needle by a dismountable syringe head that is connected in of syringe needle holder with screw thread or draw-in groove;
Then, syringe is put into by the ampoule of sealing member sealing respectively in that be filled with medicinal liquid in advance and two ends, the sealing member that has an end in the sealing member at these two ends at least is a plug that can move along the ampoule inwall;
At last, push rod is promoted described ampoule one end sealing member so that the medicinal liquid in the ampoule inject via syringe needle.
The invention has the beneficial effects as follows: spliced prefilled injector of the present invention and using method thereof have following advantage:
Because it is split type that structure changes into, the syringe needle that has therefore solved long-term puzzlement integral type Pre-filled syringe soaks the free nuclear reaction problem of the heavy metal ion that causes in medicinal liquid, so reliability of the present invention rising, and application further expands;
Adopt the high grade of transparency of new generation, and the plastic material to water, oxygen and carbon dioxide high barrier is the container of raw material as injection medicament, this high-tech material appearance is near glass material, but can not produce the easy protein that produces of glass material sticks, overcome the discoloration problem of simple glass material under the gamma ray sterilization method simultaneously, make sterilization process quick, efficiently, low-cost, therefore the hold capacity of product of the present invention and sterilization security performance further rise, and the suitable application area of packing at injectable drug further enlarges;
Because it is split type that structure changes into, the ampoule more former integral type syringe volume and the weight that hold liquid medicine injection are dwindled greatly, have therefore reduced the use of plastic material, greatly reduce cost.
Because it is split type that structure changes into, the ampoule that holds liquid medicine injection can be designed to the cylindrical of rule, and the canning line structure of the medicament of therefore annotating is simplified, and fill efficient is improved, and has reduced the cost of final products thus.
Because all parts adopt the raw materials for plastics production manufacturing, therefore use the back to adopt burning disposal easily convenient, the grammes per square metre of product is lighter simultaneously, cracky not, be convenient for carrying and transport, overcome that to adopt glass be that the syringe of raw material is easy to explosion when burning, there have surplus materials need after the burning to be buried, increases the shortcoming of the risk and cost that uses and handle;
Compare injection pen, the present invention is simple in structure easy-to-use, and cost is low, economic environmental protection;
Drugmaker is after adopting ampoule packing of the present invention, as long as simply mix syringe needle with injection, sleeve and push rod, medical worker or sufferer need not other instrument used for injection and just can inject, and the innovative value of medicinal industry chain Chinese medicine packing and medical apparatus and instruments that realized merges;
Because more common disposable syringe injection measurement is more accurate, therefore for the pharmaceutical factory, can reduce the fill amount of medicament, for sufferer, reduced when injection waste for expensive medication.
Following table has been done a horizontal comparison to product advantage of the present invention.
| The tradition disposable syringe | The integral type Pre-filled | Disposable/type injection pen repeatedly | Spliced prefilled | |
| Degree easy to use | Difference | Good | Good | Good |
| Secondary pollution | Have | Do not have | Do not have | Do not have |
| Heavy metal pollution | Do not have | Have | Have/do not have | Do not have |
| The saving of valuable medicinal liquid | Difference | Good | Good | Good |
| Application | Limitation | More extensive | Extensively | Extensively |
| The suitability for industrialized production degree | Good | Difference | Good | Good |
| Environmental economy | Good | Good | Difference | Good |
| Production cost and price | Minimum | High | The highest | Lower |
Description of drawings
Fig. 1 is the exploded view of one of the present invention's spliced prefilled injector;
Fig. 2 is one of the present invention's the preceding structural representation of spliced prefilled injector injection;
Fig. 3 is the structural representation after one of the present invention's spliced prefilled injector is injected.
The specific embodiment
The invention will be further described below in conjunction with accompanying drawing.
See also Fig. 1 to Fig. 3, there is shown a kind of spliced prefilled injector of one of the present invention, comprise syringe 1, push push rod 2 in the syringe 1, be connected in the syringe needle 3 of syringe 1 head and be placed in the outer pin medicated cap 4 of syringe needle 3, comprise that also one is arranged at syringe 1 interior, the ampoule that is filled with medicinal liquid in advance 5 between syringe needle 3 and push rod 2, the two ends of this ampoule 5 are respectively by a sealing member 51 sealing, and the sealing member 51 that wherein has an end at least is a plug that can move along ampoule 5 inwalls.
Among the present invention, ampoule 5 adopts cyclic polyolefin to make, cyclic polyolefin TOPAS is the trade name of the rare hydrocarbon copolymerized macromolecule of ring-type (COC) that develops of Ticona company, it is the transparent copolymerized macromolecule of amorphism with the rare hydrocarbon structure of ring-type, be that the cycloolefin analog copolymer (COC) that combined polymerization obtains is taken place under the metalloscene catalyst effect for double-heptene (norborene) monomer and vinyl monomer, it has and PMMA (polymethyl methacrylate, acrylic resin) optical property that is equal to mutually and have the thermostability that is higher than PC (Merlon), also have dimensional stability better etc. than PMMA and PC, also has the water vapour of improvement air-tightness, increase rigidity, thermostability, easily give advantages such as cutting performance, it has following advantage:
Good optical property: have the optical property that can be equal to mutually with PMMA and equal or surpass its thermostability with PC, also absorb water hardly owing to it, thereby the resin of the good performance of the dimensional stability etc. that still has height, it has obtained very high evaluation in the optics market segment;
Water vapour air-tightness: have very high water vapour air-tightness;
Safety: safety is good.
One end of the employing plug of sealing member 51, wherein plug adopts the medical grade butyl rubber to make.
The using method of a kind of spliced prefilled injector of two of the present invention, syringe comprise syringe 1, push push rod 2 in the syringe 1, be connected in the syringe needle 3 of syringe 1 head and be placed in the outer pin medicated cap 4 of syringe needle 3, and using method may further comprise the steps:
At first, with syringe needle 3 by syringe needle holder 31 dismountable syringe 1 heads that are connected in screw thread or draw-in groove;
Then, syringe is put into by the ampoule 5 of a sealing member 51 sealings respectively in that be filled with medicinal liquid in advance and two ends, the sealing member 51 that has an end in the sealing member 51 at these two ends at least is a plug that can move along ampoule 5 inwalls;
At last, push rod 2 is promoted ampoulies 5 one ends sealing member 51 so that the medicinal liquids in the ampoule 5 inject via syringe needle 3.
Illustrate: at present, China chronic renal failure patient sum surpasses 5,000,000, and what wherein need regularly to accept kidney dialysis treatment has 700,000～800,000 approximately.As press the kidney dialysis patient and used 1 EPO in per 3 days, calculate in theory that then China hospital needs to consume seven or eight thousand ten thousand EPO injections every year at least.If after the spliced prefilled injector of mentioning among the employing the present invention packing, not only patient's injection of can being in voluntarily, save the hardship of long drive back and forth, and will rise to the utilization ratio of the medicinal liquid of costliness, improve the efficient of treatment, manufacturer also will save cost because avoiding excessive topping up simultaneously, and improves the sales volume of product.
Need to prove: above only unrestricted technical scheme of the present invention in order to explanation, although the present invention is had been described in detail with reference to the foregoing description, those of ordinary skill in the art is to be understood that: still can make amendment or be equal to replacement the present invention, and not breaking away from any modification or partial replacement of the spirit and scope of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (6)
1. spliced prefilled injector, comprise syringe, push the interior push rod of syringe, be connected in the syringe needle of syringe head and be placed in the outer pin medicated cap of syringe needle, it is characterized in that, also comprise one be arranged in the described syringe, the ampoule that is filled with medicinal liquid in advance between syringe needle and described push rod, the two ends of this ampoule are respectively by sealing member sealing, and the sealing member that wherein has an end at least is a plug that can move along the ampoule inwall.
2. spliced prefilled injector according to claim 1 is characterized in that, described ampoule adopts cyclic polyolefin to make.
3. spliced prefilled injector according to claim 1 is characterized in that, described plug adopts the medical grade butyl rubber to make.
4. spliced prefilled injector according to claim 1 is characterized in that, described syringe needle is detachable syringe needle.
5. spliced prefilled injector according to claim 4, it is characterized in that, described syringe needle is connected with described syringe head by a syringe needle holder, the middle part of described syringe needle is passed this syringe needle holder and is fixed with it, have screw thread or draw-in groove on the described syringe needle holder, its dismountable head that is connected in described syringe.
6. the using method of a spliced prefilled injector, syringe comprise syringe, push push rod in the syringe, be connected in the syringe needle of syringe head and be placed in the outer pin medicated cap of syringe needle, it is characterized in that using method may further comprise the steps:
At first, with syringe needle by a dismountable syringe head that is connected in of syringe needle holder with screw thread or draw-in groove;
Then, syringe is put into by the ampoule of sealing member sealing respectively in that be filled with medicinal liquid in advance and two ends, the sealing member that has an end in the sealing member at these two ends at least is a plug that can move along the ampoule inwall;
At last, push rod is promoted described ampoule one end sealing member so that the medicinal liquid in the ampoule inject via syringe needle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100533363A CN101596334A (en) | 2009-06-18 | 2009-06-18 | A kind of spliced prefilled injector and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100533363A CN101596334A (en) | 2009-06-18 | 2009-06-18 | A kind of spliced prefilled injector and using method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101596334A true CN101596334A (en) | 2009-12-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2009100533363A Pending CN101596334A (en) | 2009-06-18 | 2009-06-18 | A kind of spliced prefilled injector and using method thereof |
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| CN (1) | CN101596334A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101942059A (en) * | 2010-08-13 | 2011-01-12 | 四川平康科技有限公司 | Application of cyclo olefin copolymer in preparing biological and chemical container |
| CN102858393A (en) * | 2010-03-31 | 2013-01-02 | 泰尔茂株式会社 | Prefilled Syringe |
| CN103961767A (en) * | 2013-01-31 | 2014-08-06 | 许沛新 | Pre-filled disposable syringe |
| CN104043165A (en) * | 2013-03-14 | 2014-09-17 | 张微 | Injector |
| CN112604067A (en) * | 2020-12-07 | 2021-04-06 | 湖南慧泽生物医药科技有限公司 | Cassette bottle injection box and methotrexate injection packaged by same |
-
2009
- 2009-06-18 CN CNA2009100533363A patent/CN101596334A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102858393A (en) * | 2010-03-31 | 2013-01-02 | 泰尔茂株式会社 | Prefilled Syringe |
| CN101942059A (en) * | 2010-08-13 | 2011-01-12 | 四川平康科技有限公司 | Application of cyclo olefin copolymer in preparing biological and chemical container |
| CN103961767A (en) * | 2013-01-31 | 2014-08-06 | 许沛新 | Pre-filled disposable syringe |
| CN104043165A (en) * | 2013-03-14 | 2014-09-17 | 张微 | Injector |
| CN112604067A (en) * | 2020-12-07 | 2021-04-06 | 湖南慧泽生物医药科技有限公司 | Cassette bottle injection box and methotrexate injection packaged by same |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20091209 |