CN1015872B - Method of preparing injection for whole prolapse haemorrhoids - Google Patents
Method of preparing injection for whole prolapse haemorrhoidsInfo
- Publication number
- CN1015872B CN1015872B CN 87104056 CN87104056A CN1015872B CN 1015872 B CN1015872 B CN 1015872B CN 87104056 CN87104056 CN 87104056 CN 87104056 A CN87104056 A CN 87104056A CN 1015872 B CN1015872 B CN 1015872B
- Authority
- CN
- China
- Prior art keywords
- injection
- haemorrhoids
- hemorrhoid
- prolapse
- whole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention discloses a preparation method of an injection for totally curing hemorrhoids. The injection contains high-concentration quinine dihydrochloride, quinine hydrochloride, methylene blue and haemostatic aromatic acid components. The injection is a novel agent for completely removing local necrotic tissues, and has strong functions of persistent analgesia, haemostasia and antiphlogosis. The injection is not only suitable for treating internal haemorrhoids in various stages, but also suitable for treating external haemorrhoids, mixed haemorrhoids anal fissures, rectal polyps and papillary fibroma. The injection has the advantages of high therapeutic efficiency, painlessness, short periodicity, unnecessary hospitalization and low relapse rate.
Description
The present invention relates to a kind of manufacture method of injection for whole prolapse haemorrhoids, this injection is used for the treatment of the internal hemorrhoid of each phase, external hemorrhoid, mixed hemorrhoid, anal fissure, herpes-ness rectum polyp, mamillary fibrous tissue tumor.
The sickness rate of hemorrhoid is considerably high, and treatment of hemorrhoid is also proposed various different therapy, and injection treatment is exactly wherein a kind of.1973, Jishan County, Shanxi Province hemorrhoid complicated by anal fistula hospital appoints all risk insurance at first to propose (to see barefoot doctor's magazine with the U.S. blue length of making than the method for analgesic, 15 pages of 1977 6 phases), thereby alleviate long-time pain problem in the hemorrhoid patients therapeutic process, but this injection can produce severe pain in 3～4 hours after injection, must usage degree suddenly or other pain killer injection.And list local pain occurs with quinin hydrochloride (for example compound quinine, 5～10% quinin hydrochloride carbamide) the local injection later stage.
Task of the present invention provides a kind of manufacture method for the treatment of hemorrhoid injection, and this injection makes affected part tissue or blood stasis total necrosis come off wound repair, myotube is level and smooth, it is normal that function is recovered rapidly, and relapse rate is extremely low, and has powerful long-acting analgesic and hemostatic function.
The method that the present invention proposes to make a kind of like this injection for whole prolapse haemorrhoids is as follows: get quinine dihydrochloride 15～17 grams, quinin hydrochloride 3～4.5 grams, U.S. blue 0.2～0.3 gram, Aminomethylbenzoic Acid 0.2～0.4 gram, caffeine 0.68～1.1 gram, urethane 0.56～0.8 gram, after the said medicine mixing, adding distil water to 100 milliliter has passed through filtration again, promptly makes desired injection for whole prolapse haemorrhoids after packing, the autoclaving operation.Whether this injection is blueness, odorless, bitter in the mouth, and its pH value is 6.7～7.1, when local injection is sign with black-and-blue, can clear view even to drug distribution, and medicine reach when injecting.
This injection for whole prolapse haemorrhoids has increased the content of quinine dihydrochloride, and this is a kind of local tissue necrosis agents for defoliating, and it makes the local organization dysbolismus, thrombosis in the blood vessel, the blood supply of remote organization stops, and promotes that tissue necrosis comes off, and therefore this injection is injection for whole prolapse haemorrhoids.U.S. orchid is a kind of long-acting topical pain relief agent, and the long-acting analgesic effect is arranged, and makes in treatment long-time to reach painless effect.Because the quinine dihydrochloride of high concentration, quinin hydrochloride and U.S. orchid are share, the sort of severe pain phenomenon of injection long-acting analgesic is eliminated, and injection also plays powerful long-acting analgesic effect, can be maintained to more than 8～12 days, therefore this injection not only is used for the treatment of internal hemorrhoid, and can expand the treatment external hemorrhoid to, mixed hemorrhoid, anal fissure, mamillary fibrous tissue tumor.Because the powerful long-acting analgesic effect of medicine, make the patient after sensation is day by day recovered, and cause that the time of pain is over and done with after the operation, this nonpain treatment significantly reduces partial stimulation, can not make the patient that the reflexive urine retention takes place, not have the reflexive exothermic reaction yet.
The quinine dihydrochloride of high concentration and quinin hydrochloride share and make the interior thrombosis of local vascular stronger than other sclerosing agent, and this helps hemostasis.In order to strengthen haemostatic effect, add the Aminomethylbenzoic Acid medicine in the present invention, Aminomethylbenzoic Acid has the effect of antiplasmin protein dissolution, and the mixing of these several compositions reaches synergism, makes injection back difficult local hemorrhage, even also be difficult for hemorrhage in the phase of coming off.Urethane can increase quinine dissolubility and reduce quinine part toxicity in water, and caffeine has the rehabilitation effect to nervus centralis.
The using method of injection for whole prolapse haemorrhoids:
1. each phase internal hemorrhoid, external hemorrhoid, mixed hemorrhoid.
After wanting earlier anus sterilization on every side, with 2～4 milliliters of local anesthesia of 2% procaine hydrochloride, vise 3/4ths parts (the I phase is interior without mosquito forceps) of blood stasis with curved hemostat, thereby the blood access that stops blood stasis, the injection injection for whole prolapse haemorrhoids is 0.2～1 milliliter in each blood stasis, to blood stasis become black-and-blue till, decontrol mosquito forceps after spending 2 minutes, internal hemorrhoid then should send in four anuses, the lighter's injection once, heavy person divides three injections, and injection for the second time should be after a week, injection back available 1: 3000 greatly after an action of the bowels potassium permanganate water demibain patient's every day.
2. anal fissure
Local anesthesia under breach, 0.2 centimeters is injected 0.2～0.3 milliliter of injection for whole prolapse haemorrhoids under breach, and breach is come off, and wound surface is repaired again.
3. rectal polyp
In the base of a fruit's injection, total amount is no more than 0.4 milliliter.
4. mamillary fibrous tissue tumor.
Its injecting method is with the external hemorrhoid Therapeutic Method.
The observation of curative effect of injection for whole prolapse haemorrhoids, the result is as follows, recovery from illness account for the overwhelming majority, sb.'s illness took a favorable turn to have only about 1% performances, the patient is after injection for whole prolapse haemorrhoids treatment, and downright bad tissue can come off wound healing after 6～9 days within 3～6 days, anal canal is level and smooth, and function is normal, the anal fissure transference cure.The relapse rate check result is also relatively good, and to the internal hemorrhoid of each phase, mixed hemorrhoid is followed the tracks of and traced, and does not see recurrence within 8 years as yet, and its relapse rate is 2% within 10 years.The long-acting analgesic of medicine is respond well, treats painless to account for 96%, and what the oral administration analgesic of hypodynia was alleviated accounts for 4%, and the severe pain situation did not also take place one time so far.Injection for whole prolapse haemorrhoids is because only for the injection of local affected part, most of medicinal liquid is in the local organization fast Absorption and have an effect, whole body absorbs less, non-toxic reaction, the liver function of carrying out to 11 example treatment internal hemorrhoid, routine urinalysis, blood routine examination remove 2 examples the momentary rising of leukocyte take place, and all the other are no change all.
Injection for whole prolapse haemorrhoids has the curative effect height, the characteristics that treatment cycle is short need not to be in hospital, and cure more thorough, no pain during the treatment, the areflexia urine retention, hemorrhage or heating side effect has solved the external hemorrhoid in pectinate line following (the sharp district of the pain sensation), the external hemorrhoid part of mixed hemorrhoid, anal fissure is exempted external hemorrhoid and is operated on the misery of operation once more, solves for a long time external hemorrhoid is forbidden the technical problem of injecting.
Claims (1)
1, a kind of manufacture method of the injection for whole prolapse haemorrhoids of forming by quinine dihydrochloride, quinin hydrochloride, U.S. orchid, Aminomethylbenzoic Acid, caffeine and urethane, it is characterized in that: the formula proportion of this injection for whole prolapse haemorrhoids is quinine dihydrochloride 15～17 grams, quinin hydrochloride 3～4.5 grams, U.S. blue 0.2～0.3 gram, Aminomethylbenzoic Acid 0.2～0.4 gram, caffeine 0.68～1.1 gram, urethane 0.56～0.8 gram, after the medicament mixed of prescription, adding distil water to 100 milliliter again, and through filtering packing and autoclaving operation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 87104056 CN1015872B (en) | 1987-06-02 | 1987-06-02 | Method of preparing injection for whole prolapse haemorrhoids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 87104056 CN1015872B (en) | 1987-06-02 | 1987-06-02 | Method of preparing injection for whole prolapse haemorrhoids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN87104056A CN87104056A (en) | 1988-05-18 |
| CN1015872B true CN1015872B (en) | 1992-03-18 |
Family
ID=4814700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 87104056 Expired CN1015872B (en) | 1987-06-02 | 1987-06-02 | Method of preparing injection for whole prolapse haemorrhoids |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1015872B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106860457A (en) * | 2015-12-11 | 2017-06-20 | 四川诺邦医疗科技有限公司 | A kind of pharmaceutical composition, preparation method and applications for treating secretion gland disease |
| KR101698003B1 (en) * | 2016-06-20 | 2017-01-19 | 여오영 | Injectable composition for topical administration for cancer treatment that comprising a quinine salt suspension |
-
1987
- 1987-06-02 CN CN 87104056 patent/CN1015872B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CN87104056A (en) | 1988-05-18 |
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