CN101559178B - Medicated thread for curing acute nephritis, chronic nephritis and chronic renal failure and application thereof - Google Patents
Medicated thread for curing acute nephritis, chronic nephritis and chronic renal failure and application thereof Download PDFInfo
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- CN101559178B CN101559178B CN200810050613.0A CN200810050613A CN101559178B CN 101559178 B CN101559178 B CN 101559178B CN 200810050613 A CN200810050613 A CN 200810050613A CN 101559178 B CN101559178 B CN 101559178B
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Abstract
The invention relates to a medicated thread for curing acute nephritis, chronic nephritis and chronic renal failure. The medicated thread adopts the technical scheme that a surgical catgut used for suturing a wound or a surgical incision is adopted; home-made Chinese herbal liquid medicine is utilized; then the surgical catgut is prepared into the medicated thread with medicine; and then the medicated thread possesses a new function. The medicated thread mainly used for curing various nephropathies is a new technology and a new therapy different from the traditional treatment method. The medicated thread has a therapeutic method that Chinese herbal medicines are combined with the acupuncture-moxibustion theory, and the medicated thread which is specially made is implanted into acupuncture points having unique therapeutic actions to a kidney by a special manner according to the mechanism of kidney troubles in the traditional Chinese medicines, thereby playing a role of immune regulatoryand curing the nephropathies. According to the clinical observation, the medicated thread has the advantages of good and fast curative effect for curing the acute nephritis, the chronic nephritis and the chronic renal failure, unavailable side effect, and the like.
Description
Technical field
The present invention relates to a kind of medicated line for the treatment of acute and chronic nephritis, chronic renal failure disease, meanwhile, the invention still further relates to the application of this medicated line aspect treatment acute and chronic nephritis, chronic renal failure disease and relevant disease.
Background technology
Acute and chronic nephritis belongs to the categories such as the traditional Chinese medical science " edema " (YIN edema), " asthenia ", " lumbago ", mostly be lung spleen kidney three dirty functional disorders, the metabolism of water liquid is not normal and stop gathering, wherein asthenia of pulmonosplenic qi, kidney yang deficiency for morbidity this, and accumulate in phlegm-damp, blood stasis, evil poison, be the mark causing a disease.Renal failure belongs to " drown poison ", " obstruction and rejection " category in the traditional Chinese medical science, and etiology and pathogenesis is the exopathogen three warmers that are jammed, stagnation of blood stasis channels, so that clear sun rises, turbid YIN failing to descend and turbid pathogen Yu Huawei pyretic toxicity, excessive poison enters blood, can violate stomach, invades lung, makes a psychological attack, upper brain, wind symptom and occur all syndromes.At present, international and domesticly there is no specific short and medicine, although there is the Chinese patent medicine of some treatment primary disease, because effect is not fairly obvious, patient still relies on hormone and other Western medicine mostly, but the development of the state of an illness is lost control of in temporarily onset, cures the symptoms, not the disease.
Summary of the invention
The object of the invention is to provide that a kind of cost is low, instant effect, effect is lasting, clinic control rate is high, without the medicated line of the treatment disease of the side effect of drug-induced.
Another object of the present invention is to provide a kind of preparation method of medicated line of this treatment disease.
Another object of the present invention is also to provide the application of a kind of this medicated line aspect treatment acute and chronic nephritis, renal failure and relevant disease.
The object of the present invention is achieved like this:
This medicated line is to adopt catgut to be prepared from by decoction and the process of preparing Chinese medicine of traditional Chinese medicine liquid, and described traditional Chinese medicine liquid refers to decoction liquor and alcohol extract.
Preparation method is:
A, by the ratio of weight and number of raw material, choose Radix Astragali 10-20 part, Rhizoma Dioscoreae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Imperatae 10-20 part, Polyporus 9-15 part, Rhizoma Alismatis 9-15 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Poria 9-15 part, Ramulus Cinnamomi 9-15 part, above-mentioned Ten Herbs adds water 1000ml and decocts to 300ml, is prepared from decoction liquor standby after filtration.
B, by the ratio of weight and number of raw material, choose Radix Astragali 10-20 part, Rhizoma Dioscoreae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Imperatae 10-20 part, Polyporus 9-15 part, Rhizoma Alismatis 9-15 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Poria 9-15 part, Ramulus Cinnamomi 9-15 part, above-mentioned Ten Herbs packs in wide mouthed bottle, add medical alcohol to cover bottle cap, soak 15 days, filter, get alcohol extract and insert in another wide mouthed bottle standby.
C, adopt above-mentioned decoction liquor and 20 water vinegar half and half of catgut to boil altogether 30 minutes, put into the 250ml wide mouthed bottle with alcohol extract after cooling, soak 15 days, make this medicated line.
Described catgut is 2-5 catgut.
The invention provides a kind of medicated line in the acute and chronic nephritis of preparation treatment, the application in chronic renal failure disease medicament.
The present invention also provide a kind of medicated line treatment other diseases point immunity regulate therapy.
Advantage of the present invention is:
1, we know catgut aspect medical for wound or postoperative stitching use, we adopt homemade traditional Chinese medicine liquid by the preparation technology of science, and catgut is prepared into the medicated line with medicine, make it have a kind of new purposes.
2, this medicated line is mainly used to nephritis, and the treatment of renal failure and relevant disease is different with traditional Therapeutic Method, is a kind of new technique, new therapy.Its Therapeutic Method mainly adopts Chinese medicine to combine with acupuncture and meridian theory, traditional Chinese medical science mechanism for nephropathy, special Chinese medicine medicated line is implanted to focus by special maneuver local, reach the acute and chronic nephritis for the treatment of, the object of chronic renal failure and relevant disease.
3, the acupuncture point medicated line implantation that the present invention adopts, take a broad view of whole operating process, in fact comprised the rear action effect that acupuncture point block, acupuncture, thorn blood, body tissue damage, let the acupuncture needle remain at a certain point, bury the multiple stimulating effects such as medicine and histotherapy, is that a kind of multiple therapy, multiple effect of melting is in the plyability Therapeutic Method of one.This art has proved that through the clinical practice of more than ten years chronic renal failure and relevant disease have reliable curative effect to treating acute and chronic nephritis.Its acupoint selection is few, easy and simple to handle, and the course for the treatment of, interval was long, saved time, expense is cheap, and instant effect, and clinic control rate is high, without the side effect of drug-induced, be deeply subject to nephropathy and relevant disease patient's welcome and acceptance, therefore will receive obvious Social benefit and economic benefit after applying.
the specific embodiment
Embodiment:
1, get in proportion the Radix Astragali, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, the Radix Rehmanniae, Rhizoma Imperatae, Polyporus, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Poria, Ramulus Cinnamomi Ten Herbs and add water 1000ml and decoct to 300ml, after filtration, be prepared from the red decocting liquid of xanthate standby.
2, in identical ratio, getting the Radix Astragali, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, the Radix Rehmanniae, Rhizoma Imperatae, Polyporus, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Poria, Ramulus Cinnamomi Ten Herbs packs in the wide mouthed bottle of 500ml, add 70% medical alcohol 300ml to cover bottle cap immersion 15 days, filter, get alcohol extract--xanthate deanol extract, insert in another 250ml wide mouthed bottle standby.
3, adopt from intending the red decocting liquid of xanthate and No. 2-5 20 water vinegar half and half of catgut and boil altogether 30 minutes, after cooling, put into the 250ml wide mouthed bottle of certainly intending xanthate deanol extract, soak 15 days, make this medicated line, face while using and irradiate with operating lamp, medicated line is dried and penetrated needle body.
Application Example:
This invention therapy is observed in the acute and chronic nephritis for the treatment of by 289 routine clinical cases by the court, and it is low that chronic renal failure aspect has cost, and curative effect is high, instant effect, and effect is lasting, and curative effect is safe and reliable, without the advantages such as side effect of drug-induced.
One, case selection
12-30 year 48 examples in 167 routine patients with chronic glomerulonephritis; 31-45 year 45 examples; 46-60 year 39 examples; 61-75 year 35 examples.
12-30 year 34 examples in 122 routine chronic renal failures; 31-45 year 38 examples; 46-60 year 27 examples; 61-73 year 23 examples.
Two, diagnostic criteria
According to Weng Weiliang chief editor's in 2002 < < Chinese medicine clinical pharmacology > > diagnostic criteria
Chronic nephritis diagnostic criteria
(1) onset is slow, protracted inflammation, clinical manifestation can gently can weigh, or time heavy when light.Along with PD, can there be the situations such as renal hypofunction, anemia, electrolyte disturbance to occur.
(2) can there be edema, hypertension, albuminuria, hematuria and cylinderuria etc. a kind of (as hematuria or albuminuria) in occurring or several.Clinical manifestation is varied, sometimes can be with nephrotic syndrome or severe hypertension.
(3) in the course of disease, can there is nephritis acute attack, often because infecting (as respiratory tract infection), bring out the performance of similar acute nephritis sometimes during outbreak.Some case can be alleviated automatically, and aggravation appears in some case.
Chronic renal failure diagnostic criteria
(1) endogenous creatinine clearance rate (Ccr) < 80ml/min;
(2) serum creatinine (Scr) > 133 μ mol/L;
(3) the systemic disease medical history that has chronic renal disease or involve kidney.
Three, criterion of therapeutical effect
According to Weng Weiliang chief editor's in 2002 < < Chinese medicine clinical pharmacology > > curative effect determinate standard
Chronic nephritis curative effect determinate standard
Clinic control: routine urianlysis albumen turns negative, or twenty-four-hour urine protein quantification is normal; Routine urianlysis RBC number is normal, or Urine sediments analyzer red blood cell count(RBC) is normal; Normal renal function.
Effective: routine urianlysis albumen reduces by 2 "+", or twenty-four-hour urine protein quantification reduces 40%; RBC reduces >=3/HP or 2 "+", or Urine sediments analyzer RBC count check reduces >=40%; Normal renal function or normal (differ and be no more than 15% with normal value).
Effective: routine urianlysis albumen reduces by 1 "+", or twenty-four-hour urine protein quantification reduces < 40%; RBC reduces 3/HP of < or 1 "+", or Urine sediments analyzer RBC count check reduces < 40%; Normal renal function or be improved.
Invalid: clinical manifestation and above-mentioned lab testing are all without improving or adding severe one.
Chronic renal failure curative effect determinate standard
Effective:
(1) clinical symptoms integration reduces >=60%;
(2) endogenous creatinine clearance rate increases >=20%;
(3) serum creatinine reduces >=20%.
(1) item is indispensable above, and (2), (3) possess 1, can judge.
Effective:
(1) clinical symptoms integration reduces >=30%;
(2) endogenous creatinine clearance rate increases >=10%;
(3) serum creatinine reduces >=10%;
(4) before and after treatment with logarithm or the inverse of serum creatinine, use linear regression equation analysis, its slope has clear meaning person.
(1) item is indispensable above, and other possess 1, can judge.
Stable:
(1) clinical symptoms makes moderate progress, and integration reduces < 30%;
(2) endogenous creatinine clearance rate is without reduction, or increases < 10%;
(3) serum creatinine is without increase, or reduces < 10%.
(1) item is indispensable above, and (2), (3) possess 1, can judge.
Invalid:
(1) clinical symptoms is without improving or increasing the weight of;
(2) endogenous creatinine clearance rate reduces;
(3) serum creatinine increases.
(1) item is indispensable above, and (2), (3) possess 1, can judge.
Four, Therapeutic Method
Acupoint selection: shen shu, pang kuang shu, Taixi, sp 6, Guan Yuan, the middle utmost point.
Operation: after skin routine disinfection, by 2% lignocaine local anaesthesia (1-2 centimeters is made local anaesthesia in both sides, acupuncture point), with left hand, two local anaesthesia skins have been pinched, with needle forceps, clamp the skin suture needle with medicated line, from local anaesthesia, thrust, subcutaneous tissue or flesh layer through below, acupuncture point, now notice that back and forth tractive medicated line produces after pin sense, from offside local anaesthesia, go out pin, then be close to skin and cut off two rear line heads, loosen skin, the end of a thread must not expose, and gently rubs part, medicated line is imbedded in subcutaneous tissue completely, mulching gauze one week.
Every 30-40 days sunkens cord once, can even bury 2-3 time, depending on the concrete patient's condition.
Points for attention: (1) strictly grasps sterile working, protect from infection, and while planting line with cutting needle, operation should be light, accurate, prevents broken needle.At trunk, plant line, prevent from puncturing inner membrance, damage internal organs.(2) medicated line should be embedded between subcutaneous tissue and muscle, and the implantable flesh layer in the position of fleshiness, should not plant in fatty tissue, in case liquefaction of fat flows out sepage.Medicated line head can not be exposed to skin outside, postoperative protecting from infection.As part suppuration flowing water or expose the end of a thread, can extract medicated line out, emit pus, enclosing cover dressing is also made infection and is processed.(3) according to different parts, grasp the degree of depth sunken cord, do not injure internal organs, trunk and nerve trunk, more can not directly be embedded in nerve trunk and trunk, in order to avoid cause adverse consequences (governor vessel position plant line take only spinal cord dura mater be degree).(4) position that should depart from previous treatment while repeatedly treating at a position.(5) local skin has and infects or medicated line should not be planted by ulcer place, and fever, flu, pulmonary tuberculosis active stage, bone tuberculosis, acute cardiovascular and cerebrovascular disease, unconsciousness, health extremely feeble etc. all should not be used this law; Woman gestationperiod, menstrual phase and have bleeding tendency disease patient to use cautiously.(6) after controlling by the patient's symptom of sunkening cord, preferably sunken cord 1-2 time, to consolidate curative effect, after some patients sunken cord, not obvious, the patient that just starts to take effect for the 2nd time of curative effect should arbitrarily not stop treating for the first time again.
Five, Analysis of conclusion
Table 1, point immunity regulate therapy for treating chronic nephritis 167 examples to observe, and see the following form
| Age | Case load | Clinic control | Effective | Effectively | Invalid |
| 12-30 31-45 46-60 61-75 adds up to | 48 45 39 35 167 | 30(62.5％) 27(60％) 25(64.1％) 20(57.14％) 102(61.08％) | 8(16.67％) 5(11.11％) 6(15.38％) 6(17.14％) 25(14.97％) | 5(10.42％) 7(15.56％) 4(10.26％) 5(14.28％) 26(15.57％) | 5(10.42％) 6(13.33％) 4(10.26％) 4(11.43％) 19(11.38％) |
As can be seen from Table 1, this therapy is to treatment chronic nephritis clinic control 102 examples, clinic control rate 61.08%; Effective 25 examples, obvious effective rate 14.97%; Effective 26 examples, effective percentage 15.57%; Invalid 19 examples, inefficiency 11.38%.
Table 2, point immunity regulate therapy for treating chronic renal failure 122 examples to observe, and see the following form
| Age | Case load | Effective | Effectively | Stable | Invalid |
| 12-30 31-45 46-60 61-73 adds up to | 34 38 27 23 122 | 19(55.88％) 20(52.63％) 14(51.85％) 12(52.17％) 65(53.28％) | 6(17.65％) 7(18.42％) 4(14.81％) 3(13.04％) 20(16.39％) | 4(11.76％) 5(13.16％) 5(18.52％) 4(17.39％) 18(14.75％) | 5(14.71％) 6(15.79％) 4(14.81％) 4(17.39％) 19(15.57％) |
As can be seen from Table 2, this therapy is to effective 65 examples for the treatment of chronic renal failure, obvious effective rate 53.28%; Effective 20 examples, effective percentage 16.39%; Stablize 18 examples, coefficient of stabilization 14.75%; Invalid 19 examples, inefficiency 15.57%.
Claims (3)
1. a medicated line for the treatment of acute and chronic nephritis, chronic renal failure disease, is characterized in that: this medicated line is to adopt catgut to be prepared from by decoction and the process of preparing Chinese medicine of traditional Chinese medicine liquid, and described traditional Chinese medicine liquid refers to decoction liquor and alcohol extract;
Preparation method is:
A, by the ratio of weight and number of raw material, choose Radix Astragali 10-20 part, Rhizoma Dioscoreae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Imperatae 10-20 part, Polyporus 9-15 part, Rhizoma Alismatis 9-15 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Poria 9-15 part, Ramulus Cinnamomi 9-15 part, above-mentioned Ten Herbs adds water 1000ml and decocts to 300ml, is prepared from decoction liquor standby after filtration;
B, by the ratio of weight and number of raw material, choose Radix Astragali 10-20 part, Rhizoma Dioscoreae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Imperatae 10-20 part, Polyporus 9-15 part, Rhizoma Alismatis 9-15 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Poria 9-15 part, Ramulus Cinnamomi 9-15 part, above-mentioned Ten Herbs packs in wide mouthed bottle, add medical alcohol to cover bottle cap, soak 15 days, filter, get alcohol extract and insert in another wide mouthed bottle standby;
C, adopt above-mentioned decoction liquor and 20 water vinegar half and half of catgut to boil altogether 30 minutes, put into the 250ml wide mouthed bottle with alcohol extract after cooling, soak 15 days, make this medicated line.
2. a kind of medicated line for the treatment of acute and chronic nephritis, chronic renal failure disease according to claim 1, is characterized in that: described catgut is 2-5 catgut.
3. medicated line claimed in claim 1 is in the acute and chronic nephritis of preparation treatment, the application in chronic renal failure disease medicament.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810050613.0A CN101559178B (en) | 2008-04-17 | 2008-04-17 | Medicated thread for curing acute nephritis, chronic nephritis and chronic renal failure and application thereof |
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| CN200810050613.0A CN101559178B (en) | 2008-04-17 | 2008-04-17 | Medicated thread for curing acute nephritis, chronic nephritis and chronic renal failure and application thereof |
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| CN101559178B true CN101559178B (en) | 2014-03-12 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102188758A (en) * | 2011-05-10 | 2011-09-21 | 袁明省 | Preparation method for solid implantation catgut for treating spinal diseases |
| CN103142917A (en) * | 2013-02-07 | 2013-06-12 | 安耀苍 | Medicine for treatment of chronic renal failure and its preparation method |
| KR101418093B1 (en) * | 2013-12-31 | 2014-07-10 | 조상완 | Medical thread for korean medical treatment and making method thereof |
| CN107029191B (en) * | 2017-03-07 | 2021-04-06 | 大连耀灸生物科技有限公司 | Medicinal incense for improving kidney function and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634368A (en) * | 2004-10-13 | 2005-07-06 | 杨高宗 | Chinese herbal medicine composition for treating nephritis |
| CN101015636A (en) * | 2005-12-13 | 2007-08-15 | 丽珠医药集团股份有限公司 | Novel use of Chinese-medicinal composition |
| CN1331506C (en) * | 2005-04-26 | 2007-08-15 | 王念夫 | Antitoxic medicated thread for treating hepatitis B |
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- 2008-04-17 CN CN200810050613.0A patent/CN101559178B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634368A (en) * | 2004-10-13 | 2005-07-06 | 杨高宗 | Chinese herbal medicine composition for treating nephritis |
| CN1331506C (en) * | 2005-04-26 | 2007-08-15 | 王念夫 | Antitoxic medicated thread for treating hepatitis B |
| CN101015636A (en) * | 2005-12-13 | 2007-08-15 | 丽珠医药集团股份有限公司 | Novel use of Chinese-medicinal composition |
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