CN101559147A - Prescription of novel pure traditional Chinese medicine preparation for curing hysteromyoma - Google Patents

Abstract

The invention relates to a prescription of a novel pure traditional Chinese medicine preparation for curing hysteromyoma, belonging to a pure traditional Chinese medicine preparation, in particular to a pure traditional Chinese medicine preparation for curing hysteromyoma. The novel pure traditional Chinese medicine preparation prescription comprises the following components according to the parts by weight: 25-30 of cassia twig, 29-32 of bittersweet herb, 28-34 of Japanese milkwort herb, 27-33 of tuckahoe, 26-31 of honeysuckle, 13-16 of carpet bugle, 15-20 of alisma orientale, 5-10 of baked pangolin scale and 10-15 of angelica, and then the components are prepared into oral preparation, and the prescription medicine can be also made into pills, capsules, dripping pills, suspension liquid and other forms. The invention has low cost and can effectively cure various hysteromyomas without any sequela.

Description

A kind of pure Chinese medicinal preparation prescription of novel therapeutic hysteromyoma

Technical field:

What the present invention relates to is pure Chinese medicinal preparation, and what be specifically related to is a kind of pure Chinese medicinal preparation of novel therapeutic hysteromyoma

Background technology:

Hysteromyoma is that modal basic side is benign tumor in the female sex organ, also is one of tumor common in the human body.It causes very the grieved evil of bodice numerous women except itself, also very easily concurrent oophoropathy, and exist simultaneously with adenocarcinoma of corpus uteri and cervical cancer.

Up to now, the cause of disease of hysteromyoma is still very not clear.Prove according to a large amount of clinical observations and experimental result: muscular tumor is a kind of estrogen growing tumors that depends on.Be common in the women of child-bearing age as clinical, see 30～50 years old more, especially in the high estrogen environment, as growth under the situations such as gestation, exogenous high estrogen obviously, and muscular tumor is dwindled gradually after the menopause.Muscular tumor patient often accompanies ovary hyperemia again, swells, endometrial hyperplasia is long, points out this to stimulate relevant with too much estrogen.In fact, the muscular tumor estrogen-dependent also comprises receptor.Along with hysteromyoma and the endocrine correlational study, experiment confirm muscular tumor tissue has estrogen receptor (ER) and progesterone receptor (PR) from recent years, normal muscular tissue around its density surpasses.ER, PR change with menstrual cycle.Report is arranged, and hysteromyoma increases behind application exogenous hormones and the clomiphene, suppresses or reduce sex hormone level to prevent the muscular tumor growth, dwindles muscular tumor and improves clinical symptoms, and pointing out muscular tumor is the sex hormone dependent tumor.Use antagonism gonadal hormone curable substance muscular tumor, but clinical assays muscular tumor patient and no muscular tumor women gonadal hormone, no significant difference between the two in the blood on every side.Illustrate that Yu Qishuo the generation of muscular tumor is relevant with muscular tumor patient hormone environment, not equal to be relevant with the local endocrine environmental abnormality of muscular tumor itself.As the height of estrogen concentrations in the muscular tumor than uterus muscle; The endometrial hyperplasia degree is high near the muscular tumor.The receptor situation is as the same, and estradiol receptor and PR content are all than uterus muscle height in the muscular tumor.Take place from tissue, have the hysteromyoma cell to come from the smooth muscle cell such as the immature sarcoplast of uterus muscle, blood vessel wall for a long time, but the latter's not clear and definite as yet notion on the histology.Histological research finds the small hysteromyoma that growth time is long, and the ripe smooth muscle cell that is rich in myofilament is not only arranged, and finds the immaturity smooth muscle cell seen in the fetus uterus.The generation that shows human uterus's muscular tumor may be from the atomization of undifferentiated mesenchymal cells to smooth muscle cell.Multiple myomata may be because cells of origin many kitchen ranges in myometrium are hidden.The mesenchymal cell of this not lease making is the muscular tumor germinal cell, also is the cell that the tire phase has many differentiation functions.It has medium biology, relies on estrogen propagation, by progesterone differentiation, hypertrophy.Entering remains in the undifferentiated mesenchymal cells and the immature smooth muscle cell of flesh layer after the period of maturation, occurs self seriality propagation, differentiation and loose process under female, progestogen period effects, carries out repeatedly in long-time, until forming muscular tumor.

At present, the western medical treatment hysteromyoma adopts modus operandi more, as the less invasive techniques treatment etc., but cost an arm and a leg, and very easily cause relevant sequela, as maiden, young married woman conceived difficult or at all can not be conceived, very easily cause hyposexuality to bringing orthobiosis such as negative effect etc.In China, many patients tend to Chinese traditional treatment, and the main method of Chinese traditional treatment hysteromyoma is the oral Chinese medicine preparation.Current, the pure Chinese medicine of large quantities of treatment hysteromyoma that also appeared on the market, but the subject matter that exists is: treatment cycle is long, effect is slow, Costco Wholesale is high.

Summary of the invention:

The pure Chinese medicinal preparation prescription that the purpose of this invention is to provide a kind of novel therapeutic hysteromyoma, this prescription can improve at present the various medicines of integrative therapy hysteromyoma and a series of sequela problems that various operation is brought both at home and abroad effectively.

In order to improve the existing a series of problems of above-mentioned background technology, patent drug of the present invention is achieved by the following technical programs: get Ramulus Cinnamomi 25-30 part, Herba Solani Lyrati 29-32 part, Herba Polygalae Japonicae 28-34 part, Poria 27-33 part, Flos Lonicerae 26-31 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 13-16 part, Rhizoma Alismatis 15-20 part, Squama Manis 5-10 part, Radix Angelicae Sinensis 10-15 part composition, make corresponding dosage formulation by relevant technology then.Patent drug cost cost of the present invention is low, can treat each curing hysteromyoma fast and effectively, and will not have any sequela.

The specific embodiment one:

This specific embodiment is: get Ramulus Cinnamomi 25-30 part, Herba Solani Lyrati 29-32 part, Herba Polygalae Japonicae 28-34 part, Poria 27-33 part, Flos Lonicerae 26-31 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 13-16 part, Rhizoma Alismatis 15-20 part, Squama Manis 5-10 part, Radix Angelicae Sinensis 10-15 part composition, make corresponding dosage formulation by relevant technology then.

The specific embodiment two:

This specific embodiment is above-mentioned pharmaceutical formulation is made pill, capsule, injection with the difference of the specific embodiment one.Be made into the more convenient patient of pill and capsule and take, being made into injection will be quicker than the drug effect of oral formulations to patient's curative effect.

The specific embodiment three:

This specific embodiment is affiliated pharmaceutical formulation is made into drop pill, mixes suspension, oral liquid formulations with the difference of the specific embodiment one.Be made into drop pill, mix suspension, oral solutions also increased different medications, also made things convenient for different patients' treatment requirement simultaneously.

The clinical demonstration of patent drug of the present invention has following function and effect;

Activating blood circulation to dissipate blood stasis, hard masses softening and resolving, eliminating blood stasis to promote regeneration of blood, regulating the flow of vital energy relieves the pain, and has the antiphlogistic and bactericidal that modern medicine states clearly, the effect that improves immunity.

The criterion of therapeutical effect of the clinical execution of patent drug of the present invention be in the health ministry " traditional Chinese medical science Clinical Researches of New Drugs guideline " formulated about the criterion of therapeutical effect of hysteromyoma, that is: recovery from illness, menstrual blood volume is reduced to normally, hysteromyoma disappearance or uterus obviously dwindle; Produce effects, menses reduce, and hysteromyoma dwindles, and the uterus dwindles; Invalid, menstrual blood volume does not subtract, and the hysteromyoma size does not have change, and uterus size nothing changes.

According to this standard, the inventor with regard to patent drug of the present invention in set period inner tissue's clinical treatment 100 examples.Clinical effectiveness: 89 examples of fully recovering; Produce effects 18 examples; Invalid 3 examples, total effective rate 97%.

Model case is exemplified below:

Qingdao patient Liu Nvshi, 45 years old (N2006.8-2006.10) finds that abdominal part has the cumulative lump of volume, and with stomachache, menoxenia, leucorrhea is waited disease more.Back lump more day by day increases, and 9cm * 8cm * 10cm size is arranged approximately, and ultrasound diagnosis once is diagnosed as hysteromyoma, the suggestion operative treatment, and because of financial difficulties, the patient disagrees with operation, so temporarily earlier with treatment by Chinese herbs, above prescription was taken medicine 1 month.During the B ultrasonic check, lump narrows down to 3cm * 4cm * 5cm, has not had the necessity of performing an operation, continues according to the place ahead again and obeys January, and with the disease plus-minus, lump disappears, all disease recoveries from illness.

Linyi, Shandong Mrs Wang, 38 years old (N2005.4-2005.6), patient's multiple myomata, ultrasound diagnosis: anteversion of uterus, the palace body increases, and sees that the Uterus wall size is respectively 5.5cm * 5.3cm and the low echo agglomerate of 2.8cm * 2.6cm, the internal echo inequality is diagnosed as hysteromyoma.Taking this prescription medicine checked after 15 days: anteversion of uterus, and the palace body increases, and anterior uterine wall sees that former 5.5cm * 5.3cm becomes the low echo agglomerate of 4.5cm * 4.3cm, and former 2.8cm * 2.6cm muscular tumor disappears.Took medicine again 30 days, through ultrasound diagnosis, the uterus size and form is normal, no abnormality seen.

Beijing Mrs Hua, 41 years old (N2006.11-2007.1).First visit is in November, 2006, and symptom: menstruation is leading, and amount is few, and menstrual period are long, the both sides of the chest discomfort, and the breast of breathing hard is strongly fragrant, tinnitus, headache, bitter taste, insomnia, mammary swelling is painful, and brothers' heart self-induction is hot.B ultrasonic is examined and is hysteromyoma, takes this medicine after 1 month, and breast no longer expands painful, and it is normal that menstrual blood volume begins to recover, and the ultrasound diagnosis muscular tumor disappears, and other symptom also is greatly improved, after adhered to again taking medicine that existing (in January, 2008) followed up a case by regular visits to 2 months, in 1 year not repeatedly.

Yantai, Shandong Mrs Li, 48 years old (N2006.7-2006.8), in July, 2006, B ultrasonic was diagnosed as hysteromyoma, and size is 5.4cm * 5.1cm, and the patient does not have other manifest symptom substantially before this.Took this prescription medicine 35 days, and checked through B ultrasonic; The uterus shape size is normal, uterus and bilateral adnexa no abnormality seen, and hysteromyoma disappears.

Claims (3)

1, a kind of pure Chinese medicinal preparation prescription of novel therapeutic hysteromyoma, it is characterized in that it is made up of Ramulus Cinnamomi 25-30 part, Herba Solani Lyrati 29-32 part, Herba Polygalae Japonicae 28-34 part, Poria 27-33 part, Flos Lonicerae 26-31 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 13-16 part, Rhizoma Alismatis 15-20 part, Squama Manis (processed) 5-10 part, Radix Angelicae Sinensis 10-15 part, make oral formulations then.

2,, it is characterized in that described pharmaceutical formulation is made into pill, capsule, injection according to the pure Chinese medicinal preparation prescription of right 1 described a kind of novel therapeutic hysteromyoma.

3, the pure Chinese medicinal preparation prescription of a kind of novel therapeutic hysteromyoma according to claim 1 is characterized in that described pharmaceutical formulation is made into drop pill, mixes suspension, oral liquid formulations.