CN101549108B - 改善记忆的天麻远志胶囊及其制备方法 - Google Patents
改善记忆的天麻远志胶囊及其制备方法 Download PDFInfo
- Publication number
- CN101549108B CN101549108B CN2009100944572A CN200910094457A CN101549108B CN 101549108 B CN101549108 B CN 101549108B CN 2009100944572 A CN2009100944572 A CN 2009100944572A CN 200910094457 A CN200910094457 A CN 200910094457A CN 101549108 B CN101549108 B CN 101549108B
- Authority
- CN
- China
- Prior art keywords
- rhizoma gastrodiae
- polygala
- health
- juice
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 33
- 239000002775 capsule Substances 0.000 title claims abstract description 29
- 230000015654 memory Effects 0.000 title claims abstract description 23
- 241000305492 Gastrodia Species 0.000 title claims abstract description 19
- 241000208966 Polygala Species 0.000 title claims abstract description 19
- 239000000284 extract Substances 0.000 claims abstract description 34
- 239000000843 powder Substances 0.000 claims abstract description 23
- 230000008569 process Effects 0.000 claims abstract description 12
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 241000305491 Gastrodia elata Species 0.000 claims description 27
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 21
- 238000001914 filtration Methods 0.000 claims description 6
- 238000012545 processing Methods 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 238000001694 spray drying Methods 0.000 claims description 5
- 238000013467 fragmentation Methods 0.000 claims description 4
- 238000006062 fragmentation reaction Methods 0.000 claims description 4
- 238000003825 pressing Methods 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 3
- 238000004140 cleaning Methods 0.000 claims description 2
- 230000012010 growth Effects 0.000 claims description 2
- JEIPFZHSYJVQDO-UHFFFAOYSA-N ferric oxide Chemical compound O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 13
- 230000036541 health Effects 0.000 abstract description 8
- 235000013305 food Nutrition 0.000 abstract description 6
- 239000000463 material Substances 0.000 abstract description 5
- 235000013376 functional food Nutrition 0.000 abstract description 4
- 238000002156 mixing Methods 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 238000003860 storage Methods 0.000 abstract description 2
- 230000007087 memory ability Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 70
- 241000699670 Mus sp. Species 0.000 description 65
- 241001465754 Metazoa Species 0.000 description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
- 210000002784 stomach Anatomy 0.000 description 15
- 230000002262 irrigation Effects 0.000 description 12
- 238000003973 irrigation Methods 0.000 description 12
- 238000011534 incubation Methods 0.000 description 9
- 239000003814 drug Substances 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 230000009189 diving Effects 0.000 description 6
- 238000012549 training Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 210000004556 brain Anatomy 0.000 description 4
- 230000036449 good health Effects 0.000 description 4
- 235000013402 health food Nutrition 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000006993 memory improvement Effects 0.000 description 4
- 230000001914 calming effect Effects 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 206010003694 Atrophy Diseases 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 206010039966 Senile dementia Diseases 0.000 description 2
- 230000037444 atrophy Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000009191 jumping Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 206010006100 Bradykinesia Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000146384 Glaux Species 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000006083 Hypokinesia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 241001636762 Polygala sibirica Species 0.000 description 1
- 241001080798 Polygala tenuifolia Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000003920 cognitive function Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 235000018927 edible plant Nutrition 0.000 description 1
- -1 electuary Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000036732 histological change Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000007787 long-term memory Effects 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 230000006386 memory function Effects 0.000 description 1
- 206010027175 memory impairment Diseases 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000006403 short-term memory Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000000225 synapse Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
剂量组(mg/kgBW) | 动物数(只) | 到达终点时间(±s,秒) | P值 |
0 | 10 | 402.0±64.2 | ---- |
200 | 10 | 372.3±75.1 | 0.731 |
400 | 10 | 315.5±61.7 | 0.042 |
800 | 10 | 280.8±83.7 | 0.003 |
剂量组(mg/kgBW) | 动物数(只) | 到达终点前错误次数(±s,次) | P值 |
0 | 10 | 38.80±6.43 | ---- |
200 | 10 | 35.40±7.74 | 0.748 |
400 | 10 | 31.70±6.26 | 0.037 |
800 | 10 | 24.40±8.14 | 0.000 |
剂量组(mg/kgBW) | 动物数(只) | 试验次数 | 2min内到达终点的动物数 | P值 |
0 | 10 | 5 | 37/50 | ---- |
200 | 10 | 5 | 41/50 | 0.335 |
400 | 10 | 5 | 44/50 | 0.072 |
800 | 10 | 5 | 45/50 | 0.035 |
剂量组(mg/kgBW) | 动物数(只) | 错误动物数/受试动物数 | P值 |
0 | 10 | 5/10 | ---- |
200 | 10 | 4/10 | 1.000 |
400 | 10 | 2/10 | 0.340 |
800 | 10 | 1/10 | 0.144 |
剂量组(mg/kgBW) | 动物数(只) | 测验错误动物数/受试动物数 | P值 |
0 | 10 | 7/10 | ---- |
200 | 10 | 6/10 | 1.000 |
400 | 10 | 5/10 | 0.644 |
800 | 10 | 2/10 | 0.070 |
剂量组(mg/kgBW) | 动物数(只) | 到达终点时间(±s,秒) | P值 |
0 | 10 | 391.4±70.9 | ---- |
200 | 10 | 364.6±60.7 | 0.716 |
400 | 10 | 330.7±67.8 | 0.163 |
800 | 10 | 296.4±90.9 | 0.017 |
剂量组(mg/kgBW) | 动物数(只) | 到达终点前错误次数(±s,次) | P值 |
0 | 10 | 41.80±7.74 | ---- |
200 | 10 | 39.20±4.31 | 0.714 |
400 | 10 | 34.10±4.84 | 0.031 |
800 | 10 | 30.40±8.74 | 0.001 |
剂量组(mg/kgBW) | 动物数(只) | 试验次数 | 2min内到达终点的动物数 | P值 |
0 | 10 | 5 | 36/50 | ---- |
200 | 10 | 5 | 40/50 | 0.359 |
400 | 10 | 5 | 44/50 | 0.045 |
800 | 10 | 5 | 44/50 | 0.045 |
剂量组(mg/kgBW) | 动物数(只) | 测验错误动物数/受试动物数 | P值 |
0 | 10 | 5/10 | ---- |
200 | 10 | 5/10 | 1.000 |
400 | 10 | 3/10 | 0.630 |
800 | 10 | 2/10 | 0.342 |
剂量组(mg/kgBW) | 动物数(只) | 测验错误只数/受试动物数 | P值 |
0 | 10 | 6/10 | ---- |
200 | 10 | 3/10 | 0.382 |
400 | 10 | 2/10 | 0.178 |
800 | 10 | 0/10 | 0.012 |
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009100944572A CN101549108B (zh) | 2009-05-13 | 2009-05-13 | 改善记忆的天麻远志胶囊及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009100944572A CN101549108B (zh) | 2009-05-13 | 2009-05-13 | 改善记忆的天麻远志胶囊及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101549108A CN101549108A (zh) | 2009-10-07 |
CN101549108B true CN101549108B (zh) | 2012-04-18 |
Family
ID=41153751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009100944572A Expired - Fee Related CN101549108B (zh) | 2009-05-13 | 2009-05-13 | 改善记忆的天麻远志胶囊及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101549108B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102293945A (zh) * | 2011-09-21 | 2011-12-28 | 大连海晏堂生物有限公司 | 一种复方海参胶囊及其制备方法 |
CN104338017B (zh) * | 2013-07-29 | 2017-05-17 | 贵州益佰制药股份有限公司 | 具有改善睡眠作用的药物组合物及制法和应用 |
CN116898929A (zh) * | 2023-07-21 | 2023-10-20 | 大彭世纪科技有限公司 | 一种安神补脑保健汤 |
-
2009
- 2009-05-13 CN CN2009100944572A patent/CN101549108B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101549108A (zh) | 2009-10-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103719498B (zh) | 一种提高免疫力的黄精保健茶及其制备方法 | |
CN103007146B (zh) | 一种增强记忆力的保健营养粉 | |
CN105524822B (zh) | 一种刺梨蜂蜜晒醋制备工艺 | |
CN102038048A (zh) | 一种治疗哮喘咳嗽的保健茶及其制备方法 | |
CN103602551B (zh) | 一种有助于消食健胃复方中草药发酵保健酒及其生产方法 | |
CN104388265A (zh) | 一种益肾养生滋补酒及其制备方法 | |
CN103690753A (zh) | 药酒制备过程中药材处理方法、保健药酒及其制备方法、用途 | |
CN103719497A (zh) | 一种绞股蓝降脂减肥保健茶及其制备方法 | |
CN107156828A (zh) | 一种适用于炎性肠病患者的全营养配方食品 | |
CN105558147A (zh) | 一种姜茶及其制备方法 | |
CN103689152B (zh) | 一种补肾清肝凉茶及其制备方法 | |
CN103444928A (zh) | 一种春季养身早茶袋泡茶 | |
CN101549108B (zh) | 改善记忆的天麻远志胶囊及其制备方法 | |
KR20020048212A (ko) | 숙취해소용 음료 및 그 제조방법 | |
CN108042683A (zh) | 一种抗霾清肺的药食同源产品 | |
CN104474472A (zh) | 具有降三高作用的苦丁茶含片及其生产方法 | |
CN107836619A (zh) | 一种具有增强免疫力和抗疲劳作用的牛大力固体饮料及其制备方法 | |
CN104206595A (zh) | 一种降脂降糖的地骨皮保健茶及其制备方法 | |
CN103283893B (zh) | 一种罗城毛葡萄籽富贵茶及其制备方法 | |
CN106860814B (zh) | 一种改善女性尿频、尿失禁的保健食品组合物及其制备方法和应用 | |
CN106978309A (zh) | 一种参蚁酒及制备方法和用途 | |
CN103798435A (zh) | 佛手桑叶枸杞茶及其制备方法 | |
CN103417886A (zh) | 一种治疗支气管哮喘的中药组合物及其制备方法 | |
CN103689602B (zh) | 一种高丽红参口服液的制备方法 | |
CN104721248B (zh) | 具有抗抑郁作用的组合物及其用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: WANG JING Free format text: FORMER OWNER: TAO GUOWEN Effective date: 20141119 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C53 | Correction of patent of invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Wang Jing Inventor before: Tao Guowen |
|
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 650106 KUNMING, YUNNAN PROVINCE TO: 650000 KUNMING, YUNNAN PROVINCE Free format text: CORRECT: INVENTOR; FROM: TAO GUOWEN TO: WANG JING |
|
TR01 | Transfer of patent right |
Effective date of registration: 20141119 Address after: 650000 No. 7, Donghua 30, Donghua District, Guandu District, Yunnan, Kunming Patentee after: Wang Jing Address before: 650106 Yunnan province Haiyuan Kunming high tech Development Zone No. 6 North Road, building nine floor high tech investment Patentee before: Tao Guowen |
|
TR01 | Transfer of patent right |
Effective date of registration: 20211020 Address after: 629000 No. 17, group 9, Hongmiao village, Yufeng Town, Anju District, Suining City, Sichuan Province Patentee after: Shi Guangji Address before: 650000 No. 30, courtyard 7, Donghuali, Donghua community, Guandu District, Kunming, Yunnan Province Patentee before: Wang Jing |
|
TR01 | Transfer of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120418 |
|
CF01 | Termination of patent right due to non-payment of annual fee |