CN101537144A - Chinese material medical preparation for treating esophagus cancer and gastric cancer of digestive system - Google Patents

Chinese material medical preparation for treating esophagus cancer and gastric cancer of digestive system Download PDF

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CN101537144A
CN101537144A CN200910022220A CN200910022220A CN101537144A CN 101537144 A CN101537144 A CN 101537144A CN 200910022220 A CN200910022220 A CN 200910022220A CN 200910022220 A CN200910022220 A CN 200910022220A CN 101537144 A CN101537144 A CN 101537144A
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gastric cancer
chinese medicine
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CN101537144B (en
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李玉萍
张岚
张翠香
田军政
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Abstract

The invention relates to a Chinese material medical preparation for treating esophagus cancer and gastric cancer of the digestive system, raw materials of which are made by the following components according to the weight account: 10-30 portions of night shade, 15-30 portions of woody nightshade, 15-120 portions of Chinese actinidia root, 10-60 portions of marsdenia tenacissima, 3-15 portions of airpotato yam, 15-60 portions of sticktight, 3-9 portions of trifoliate orange, 3-9 portions of endothelium corneum gigeriae galli, 10-30 portions of malt, 10-30 portions of rhizoma imperatae and 15-30 portions of Chinese Lobelia. The Chinese material medical preparation is taken by hundreds of patients for more than ten years so as to prove that the treatment effect is better without toxic side effect, and the effects of improving immunizing power, promoting digestive absorption and preventing canceration from dispersing are obtained by the patients suffered from the esophagus cancer and the gastric cancer, and has remarkable getting-well effect to especially cancer postoperative patients.

Description

The Chinese medicine preparation of treatment digestive system esophageal carcinoma and gastric cancer
Technical field
The invention belongs to the pharmaceutical product technical field, particularly a kind of Chinese medicine preparation for the treatment of cancer in digestive system.
Background technology
Esophageal carcinoma (carcinomaofe sophagus) is the malignant tumor of esophagus squamous epithelial cancer, and carrying out property acataposis is its most typical clinical symptoms.This disease is one of human common malignancy.China is the country occurred frequently of esophageal carcinoma, also is this highest country of disease mortality rate.The annual esophageal carcinoma new cases in the whole world are about 31.04 ten thousand, and China accounts for 16.72 ten thousand.The definite etiology unknown of esophageal carcinoma.Obviously, environment and some carcinogen are important paathogenic factors.Mainly comprise: 1. nitrosamine compound and mycotoxin.Existing known have nearly 30 kinds of nitrosamine can bring out animal tumor.China's investigation finds that in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, and are proportionate these materials the easy syncarcinogen nitrosamine of gastric with ground esophageal carcinoma and the outgrowth prevalence of epithelium of esophagus severe.2. esophageal injury, esophagel disease and The food stimulation effect.Esophageal injury and some esophagel disease can inspire esophageal carcinoma.In corrosive burn of esophagus and narrow, achalasia of cardia and esophagus, diverticulum of esophagus or reflux esophagitis patient, the general crowd of the sickness rate of esophageal carcinoma be a height.Be to cause secular chronic inflammatory disease, ulcer by inference owing to being detained in the esophagus, or chronic stimulation, and then esophageal epithelial proliferation, canceration caused at last.3. malnutrition and trace element deficiency.Taking in animal proteinum deficiency and vitamin A, B2, C shortage, is the common feature of esophageal carcinoma high district resident diet.4. inherited genetic factors.The morbidity of esophageal carcinoma often shows the family clustering phenomena.
Gastric cancer is the former a kind of common malignancy that betides stomach.This disease mainly be edible contain the carcinogenic food of inferior ammonium nitrate as smoke food, sauerkraut, due to the food that goes mouldy etc.Chronic atrophic gastritis and gastric cancer substantial connection arranged, intestinal epithelial metaplasia and intestinal-type gastric cancer in addition, digestive tract ulcer is relevant with the cercinoma prophase pathologic change of gastric cancer.
Belong to the esophageal carcinoma and the stomach cancer metastasis relapse rate height of digestive system, western medical treatment is relatively poor to this curative effect, so the survival rate of its canceration is lower.Esophageal carcinoma middle and advanced stage local symptom is very outstanding, even the dysphagia that local stenosis causes after the operation, radiotherapy is still more.Among quite a few patient of esophageal carcinoma and gastric cancer nutritious bad, become thin, have a delicate constitution, Chinese medicine has suitable advantage aspect having additional nutrients improving body constitution; Treatment by Chinese herbs has attenuation, potentiation, sensitization during the operation chemicotherapy; Many late internal organs shift among the patient, because radiotherapy can't be used, chemotherapeutic efficacy is not good enough again, and the toxicity patient can't bear again, Chinese medicine can play mitigate the disease, improves quality of life, prolong life cycle this moment, even can suppress tumor growth, reached the purpose of band tumor existence.Nearly recent decades, because Chinese medicine has significantly reduced the transfer and relapse rate of esophageal carcinoma and gastric cancer, and made most of patients with terminal prolong life in the extensive use of tumor area, part can return to one's perfect health.
Therefore, utilize Chinese medicine preparation at present, reduce one of its research emphasis painful and effectively its life tcm field of prolongation cancer patient's rehabilitation.
Summary of the invention
The object of the invention provides a kind of Chinese medicine preparation for the treatment of digestive system esophageal carcinoma and gastric cancer.
The etiology and pathology of esophageal carcinoma is mainly reflected in gas, the stasis of blood, expectorant, poison, empty five words, clinical symptoms show as choke, tell, bitterly, stalk, void.Face card and should note determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, select medicine flexibly.Esophageal carcinoma is the card of deficiency in origin and excess in superficiality, and the method for treatment emphasis is a body resistance strengthening and constitution consolidating, is earlier especially with the strengthening spleen, tonifying kidney, and is real at mark, focuses on blood circulation promoting and blood stasis dispelling, resolving phlegm and softening hard masses.The esophageal carcinoma patient has the syndrome of failure of stomach-QI to descend more, so clinical treatment needs the product that logical lung sending down the abnormal ascending QI peace is dashed of noting using more.Primary disease is real to take stopgap measures in early days, focuses on dispersing the stagnated live-QI to relieve the stagnation of QI, dissipating phlegm and resolving masses, and sending down the abnormal ascending QI is main, notices that assistant is to moisturize; Mid-term, simulataneous insufficiency and excessive was answered reinforcement and elimination in combination.Late period, healthy energy was lost void, controlled and should set upright by tonify deficiency, the suitable strengthening spleen, tonifying kidney of method, supplementing QI and nourishing YIN, nourishing blood to promote the production of body fluid, the eliminating evil method of holding concurrently.
The precancerous lesion of gastric cancer has gastric ulcer, polyp of stomach, chronic atrophic gastritis etc., and early symptom is also not obvious, is therefore easily ignored by people, and progressive stage and middle and advanced stage gastric cancer symptom be the typical case, often is the reason that the patient removes hospital admission.In view of the difference of different patient's etiology and pathogenesis and individual instances, and the characteristics of gastric cancer clinical symptoms in each different in period, should select targetedly different therapies when treatment.The probability of middle and advanced stage patient operation is little, and effect is also bad, even if can perform the operation also is local excision, from clinical observation, the middle and advanced stage patient adopts combination of Chinese and Western medicine effect better, for the patient of middle and advanced stage, doctor trained in Western medicine adopts radiotherapy more, chemotherapy, the two all has comparatively directly inhibitory action to cancerous cell, but also can cause damage to the human immune system, most of patients leukopenia can occur, bone marrow depression after the radiotherapy of carrying out one period or chemotherapy, alopecia, a series of symptoms such as weak, physical function seriously descends, to treatment carry out smoothly unfavorable.Therefore, the middle and advanced stage patients with gastric cancer should be treated in conjunction with Chinese medicine, can reduce the toxic and side effects of chemicotherapy, human body immunity improving power, effectively suppress cancer pain, and chemicotherapy had potentiation, so the combination of Chinese and Western medicine can significantly improve life quality for the middle and advanced stage patient, reach curative effect preferably.As fully visible, the curing gastric cancer different times is selected distinct methods, have great importance for the healing of disease, and determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, treatment just can reach the effect that As the medicine took effect, the symptoms lessened targetedly.Comprise that the body resistance strengthening and constitution consolidating and blood circulation promoting and blood stasis dispelling are main thought.The body resistance strengthening and constitution consolidating " be the fundamentum of Chinese traditional treatment gastric cancer, also be modern Application method the most widely.Modern study thinks that the main effect of the body resistance strengthening and constitution consolidating method is to keep the stability of organismic internal environment, improves immunologic function.Use Fu Zheng Pei Ben drug and can improve the T lymphocyte activity; activating macrophage promotes interferon to produce, protection bone marrow, adrenal cortex and liver function; with interleukin-2 synergism is arranged, some set upright the effect that Chinese medicine also has antioxidation and knows free radical.Gastric cancer is treated in the body resistance strengthening and constitution consolidating ruling by law abundant intension.At first, use the body resistance strengthening and constitution consolidating method and not only want " tonifying for the exhaustion ", more need " transferring its bias ".Gu person's what is called " using warming therapy and it, is transferred it, is supported it.All mend also " this implication just.Chinese medicine emphasizes that always " organic conception " is particularly in oncotherapy, by coordinating YIN and YANG QI and blood balance, make body recovery arrive the state of " YIN and YANG in a relative equilibrium ", usually can obtain the modern medicine satisfactory effect that is beyond one's reach, really embody the treatment advantage of Chinese medicine.Secondly, " set upright do not forget eliminating evil " is the marrow that gastric cancer is treated in the body resistance strengthening and constitution consolidating ruling by law.Because gastric cancer is the disease of a kind of " whole for empty, the part is real ", the treatment of any single machinery all can deviate from the state of an illness, therefore imposes " it is main setting upright, and holds concurrently with eliminating evil ", can not lose its method for the body resistance strengthening and constitution consolidating rule, and can change flexibly.Gastric cancer is treated in the ruling by law of utilization the body resistance strengthening and constitution consolidating, and clinical how starting with from function of spleen and stomach regulating specifically is divided into invigorating the spleen and benefiting QI, reinforcing stomach reg fluid two methods again.In a word, the body resistance strengthening and constitution consolidating method is under traditional Chinese medical science organic conception instructs, and the thought of following the harmony between man and nature, equilibrium between yin and yang produces and the development of enriching constantly.It not only requires to help human righteousness's deficiency, has also emphasized assistance yang blood and qi balance, makes it to reach the purpose of " YIN and YANG in a relative equilibrium ".Along with the development of modern medicine, the significance of the anti-cancer ability of recognizing body in curing gastric cancer that more and more scholars is also deep, these have just reflected the thought of traditional Chinese medical science reinforcing body resistance.Simultaneously, the traditional Chinese medical science thinks that also the generation of gastric cancer and the congestion relation that stagnates is very close.Congestion is the pathological product in the multiple disease progression process, but congestion forms afterwards its disease of secondary again simultaneously.Blood circulation promoting and blood stasis dispelling is the important rule of Chinese traditional treatment difficult diseases.The hemorheology index of patients with gastric cancer is often unusual clinically, and the traditional Chinese medical science thinks that this is relevant with congestion.Modern study also proves directly cancer inhibitting and killing cell of activating blood and removing stasis drug, improves hemorheology and coagulability, and blood viscosity lowering suppresses biologically active pdgf; Fibrinolysis enhancing, antithrombotic is eliminated microcirculation disturbance, thus the effect of performance metastasis has potentiation to chemicotherapy, also has effects such as immune opsonic action and paroxysmal pain, antiinflammatory, infection.Utilization stasis gastric cancer should be according to clinical syndrome differentiation, the legislation medication.Though activating blood and removing stasis Method is the important rule of treatment gastric cancer, can set upright class drug matching with resistance and supplementing qi medicine, yin-nourishing drug etc. clinically uses, and many Chinese medicines have the ability of two-ways regulation, might realize making tumor cell not only to be difficult for the effect that comes off but also be difficult for adhering at a distance by the reasonable compatibility medication.This also points out us experimentation and clinical close the combination just should to be helped treating problem comprehensively simultaneously, and the patient is obtained the effective treatment.
Specifically, the Chinese medicine preparation of treatment digestive system esophageal carcinoma and gastric cancer, it is to make with the raw material of Chinese medicine of following weight parts:
Herba Solani Nigri 10-30, Herba Solani Lyrati 15-30, Radix Actinidiae Chinensis 15-120, Caulis Marsdeniae Tenacissimae 10-60, Rhizoma Dioscoreae Bulbiferae 3-15, Herba Bidentis Bipinnatae 15-60, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 3-9, Endothelium Corneum Gigeriae Galli 3-9, Fructus Hordei Germinatus 10-30, Rhizoma Imperatae 10-30, Herba Lobeliae Chinensis 15-30.
The prescription that the present invention recommends is:
Herba Solani Nigri 15-30, Herba Solani Lyrati 15-30, Radix Actinidiae Chinensis 30-60, Caulis Marsdeniae Tenacissimae 15-30, Rhizoma Dioscoreae Bulbiferae 3-15, Herba Bidentis Bipinnatae 15-60, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 3-9, Endothelium Corneum Gigeriae Galli 3-9, Fructus Hordei Germinatus 15-30, Rhizoma Imperatae 10-30, Herba Lobeliae Chinensis 15-30.
The prescription that the present invention further recommends is:
Herba Solani Nigri 20, Herba Solani Lyrati 20, Radix Actinidiae Chinensis 60, Caulis Marsdeniae Tenacissimae 30, Rhizoma Dioscoreae Bulbiferae 10, Herba Bidentis Bipinnatae 40, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 5, Endothelium Corneum Gigeriae Galli 5, Fructus Hordei Germinatus 15, Rhizoma Imperatae 20, Herba Lobeliae Chinensis 20.
Tcm components thing effect of the present invention is:
Herba Solani Nigri-heat clearing away toxin expelling, the blood detumescence of loosing, inducing diuresis for treating stranguria syndrome.
Herba Solani Lyrati-heat clearing away toxin expelling, dampness removing jaundice eliminating, expelling wind and removing dampness.
Radix Actinidiae Chinensis-heat clearing away toxin expelling, promoting blood circulation and detumescence.
Caulis Marsdeniae Tenacissimae-anticancer dispersing, relieving cough and asthma.
Rhizoma Dioscoreae Bulbiferae-toxin expelling softening the hard mass, cooling blood for hemostasis, relieving cough and asthma.
Herba Bidentis Bipinnatae-heat clearing away toxin expelling, promoting blood circulation to remove blood stasis, bowel relieving antidiarrheal.
Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus)-promoting the circulation of QI to relieve pain, the heat clearing away toxin expelling.
Endothelium Corneum Gigeriae Galli-invigorating the stomach and promoting digestion, the astringency inducing reducing urination, calculus disappears.
Fructus Hordei Germinatus-invigorating the stomach and promoting digestion, soothing the liver galactopoiesis.
Rhizoma Imperatae-clearing away heat and promoting production of body fluid, clearing away heat and cooling blood, inducing diuresis to remove edema.
Herba Lobeliae Chinensis-heat clearing away toxin expelling, inducing diuresis to remove edema.
The present invention is directed to the present situation of cancer in digestive system pilosity, the characteristics of having something in common in conjunction with the reason of curing the disease of esophageal carcinoma, gastric cancer in conjunction with clinical practice, through groping for many years, sum up the pure Chinese medicinal preparation that the treatment cancer in digestive system comprises esophageal carcinoma, gastric cancer again.Through clinical the taking of more than ten years hundreds of patients, prove to have no side effect that therapeutic effect is good, have the immunity of raising, facilitating digestion absorption for esophageal carcinoma, patients with gastric cancer, prevent the effect of canceration diffusion.Special rehabilitation for patient behind the cancer operation has effect clearly.
The specific embodiment
Embodiment 1: take by weighing the following medicine (unit: restrain, down together) through cleaning-drying:
Herba Solani Nigri 10, Herba Solani Lyrati 30, Radix Actinidiae Chinensis 15, Caulis Marsdeniae Tenacissimae 60, Rhizoma Dioscoreae Bulbiferae 3, Herba Bidentis Bipinnatae 60, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 3, Endothelium Corneum Gigeriae Galli 9, Fructus Hordei Germinatus 10, Rhizoma Imperatae 30, Herba Lobeliae Chinensis 15.All components is mixed and made into the watered pill and gets final product.
Embodiment 2:
Herba Solani Nigri 30, Herba Solani Lyrati 15, Radix Actinidiae Chinensis 60, Caulis Marsdeniae Tenacissimae 15, Rhizoma Dioscoreae Bulbiferae 15, Herba Bidentis Bipinnatae 15, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 9, Endothelium Corneum Gigeriae Galli 3, Fructus Hordei Germinatus 30, Rhizoma Imperatae 10, Herba Lobeliae Chinensis 30.All components is mixed and made into capsule and gets final product.
Embodiment 3:
Herba Solani Nigri 20, Herba Solani Lyrati 20, Radix Actinidiae Chinensis 60, Caulis Marsdeniae Tenacissimae 30, Rhizoma Dioscoreae Bulbiferae 10, Herba Bidentis Bipinnatae 40, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 5, Endothelium Corneum Gigeriae Galli 5, Fructus Hordei Germinatus 15, Rhizoma Imperatae 20, Herba Lobeliae Chinensis 20.All components is mixed and made into powder and directly takes and get final product.
Through clinical use for many years, proving has good effect to digestive system cancer patient postoperative rehabilitation with medicine of the present invention.Be respectively that esophageal carcinoma patient and patients with gastric cancer are used data of the present invention below.
The foregoing description is as follows to the treatment clinical report of esophageal carcinoma and gastric cancer:
One, the present invention gets involved radiotherapy in the treatment esophageal carcinoma 45 routine clinical reports
L, data and method
1.1 physical data
45 routine patient ages 45~68 years old, average 57.5 years old.Be divided at random matched group f radiation alone) 22 examples and treatment group (radiotherapy+Chinese medicine) 23 examples.Two groups of clinical data there was no significant differences have comparability.
The capable conventional radiotheraphy of 1-2 Therapeutic Method matched group.The treatment group is taken preparation of the present invention on the basis of conventional radiotheraphy, each 10 grams, finish until radiotherapy every day three times.
2, therapeutic effect efficacy assessment standard:
The I level: the pathological changes complete obiteration, esophageal wall is soft and smooth, and the wriggling expansion is good, and the mucosa clean mark is as seen;
The II level: pathological changes disappears substantially, and esophageal wall is smooth, and the barium agent can be passed through smoothly, but tube wall is still stiff or narrow, and peristalsis does not recover, and the mucosa texture increases slightly;
The III level: pathological changes is clearly better, and the esophagus focus is shunk back over half. and do not have obviously distortion, become the ulcer outside angle and the outstanding chamber.Thick barium agent can be passed through.
IV level: the residual or deterioration of pathological changes. pathological changes disappears less than half or becomes the angle, twists the ulcer outside the obvious or outstanding chamber, and extreme difference is passed through in the barium agent.
Treatment organizes that effect reaches I level person 11 examples in 23 examples, II level person 9 examples, III level person 2 examples, IV level person 1 example.
Reach I level person 5 examples in matched group 22 examples, II level person 9 examples, III level person 6 examples, IV level person 2 examples.The I level remission rate of treatment group is higher than matched group, and its side reaction is lighter, and the untoward reaction that is occurred is based on slight gastrointestinal reaction.
Two groups relatively have statistical significance (rank test P<0.05).
3, sum up: radiotherapy is one of main treatment means of esophageal carcinoma, although radiotherapy technology is brought in constant renewal in, local unsteered cause makes that middle and advanced stage esophageal carcinoma radiotherapy cure rate is low, and 5 years total survival rates are low, easily recurrence.Easily the main former act of violence of recurrence may be that immunologic function more becomes low after the tumor patient radiotherapy, the disorder of cytokine secretion network regulation: radiotherapy simultaneously makes body be in hypercoagulability, and increase the weight of with tumor development, be easy to cancerous cell and platelet etc. and form cancer embolus, escape immune surveillance, radiotherapy stress back body hypercoagulability increase the weight of, and is beneficial to residual cell growth recurrence, forms vicious cycle.The traditional Chinese medical science thinks that various radioactive sources all belong to pyretic toxicity, and its property is biased, is applied to the clinical implied meaning treating the poisonous disease with poisonous drugs of the esophageal carcinoma, is intended to eliminating evil.Right its sharp bias. usually cause the loss of the damage, particularly cloudy Tianjin of body healthy energy inevitably.But doctor trained in Western medicine can not finely be controlled the side reaction of radiotherapy.So the Comprehensive Treatment of the esophageal carcinoma more and more comes into one's own.A certain proportion of anoxic cell has the radiation negation in the malignant cell, thereby reduced the curative effect of radiotherapy, because the local blood supply of esophagus is poor, the hypoxic tumor cells that contains higher proportion, use energy microcirculation improvement and blood stickinesses such as drug for invigorating blood circulation and eliminating stasis Radix Salviae Miltiorrhizae, thereby make tumor blood for increasing, weary oxygen zone dwindles, and plays synergic effect.SHENMAI ZHUSHEYE QI invigorating, yin nourishing, promote the production of body fluid, alleviate the radiotherapy toxic and side effects.Modern pharmacological research shows that this medical instrument has the effect that reduces the mitochondrion oxygen consumption, can promote immunomodulating, and lymphocytic propagation and division effect are had obvious facilitation, improves the immunologic function of bone-marrow-derived lymphocyte, the effect of activating macrophage.Macrophage is strengthened the tumor-killing effect, improve the interferon output of virus induction, can improve total white blood cells in the tip blood, improve the content of CAMP in patient's blood plasma.
In sum, radiotherapy merges uses treatment by Chinese herbs middle and advanced stage esophageal carcinoma of the present invention to show good short term effect, and can alleviate the toxic and side effects of radiotherapy to the patient, and its late result waits further follow-up observation.
Two, Chinese Medicine and Clavicular gets involved chemotherapeutic treatment late gastric cancer 40 examples
The inventor treats late gastric cancer 40 examples, and compares with simple intervention chemotherapy 30 examples with Chinese Medicine and Clavicular selectivity coeliac artery artery intubation chemotherapy (hereinafter to be referred as getting involved chemotherapy), and short term effect is satisfied.Be reported as follows.
1 object and method
1.1 object is divided into 70 routine late gastric cancer patients at random: get involved chemotherapy in conjunction with treatment by Chinese herbs group (hereinafter to be referred as the treatment group) 40 examples, male 31 examples, women 9 examples; Age 34-72 year, average 58 years old. pathological diagnosis is: adenocarcinoma 34 examples, mucinous adenocarcinoma 4 examples, carcinoid 2 examples. artery intubation chemotherapy is 60 times altogether. get involved chemotherapy group (hereinafter to be referred as matched group) 30 examples merely, male 19 examples, women 11 examples; Age 35-74 year, average 59 years old. pathological diagnosis: adenocarcinoma 26 examples, mucinous adenocarcinoma 3 examples, signet-ring cell carcinoma 1 example. artery intubation chemotherapy is 45 times altogether.
1.2 method treatment group 40 examples adopt and are used Chinese medicine when getting involved chemotherapy.Chinese medicine preparation is a preparation of the present invention, takes 30 grams every day, divides the morning, noon and afternoon to take for three times.This group gets involved chemotherapy simultaneously, the same matched group of chemotherapy regimen.The simple application of matched group 30 examples got involved chemotherapy, adopts the Seldinger method, percutaneous femoral artery puncture intubate, after being inserted to coeliac artery, insert left gastric artery or common hepatic artery according to the lesion locations selectivity, or gastroduodenal artery, behind the radiography confirm, with chemotherapeutics ametycin (MMC) 6-18mg, fluorouracil (5-FU) 0.5-1.0g, cisplatin (CDDP) 40-60mg slowly injects after the dilution, and 5min has pushed away, extract conduit, local compression 15min waits not have hemorrhage, and wrapping finishes operation.
2 results
2.1 curative effect was according to national antitumor drug curative effect universal standard evaluation in 1978.
Treatment is organized in 40 examples, CR 1 example, and PR 27 examples, SR 8 examples, NR 4 examples, in total effective rate 90%. matched groups 30 examples, CR 1 example, PR 11 examples, SR 8 examples, NR 10 examples, total effective rate 66.7%. compares P<0.05 for two groups.
2.2 survival rate adopts life table method: it is that 87.6%, 1 year survival rate is that 6 months survival rates of 56.8%. matched group 30 routine patient treatments are that 75.5%, 1 year survival rate is 42.3%. that 6 months survival rates of 40 routine patient treatments are organized in treatment
3 discuss
From two groups of late gastric cancer patient treatment results, Chinese Medicine and Clavicular arterial cannulation chemotherapy, short term effect is satisfied, effective percentage is apparently higher than not using Chinese drug-treated group (P<0.05). and prompting Chinese medicine has potentiation preferably to getting involved chemotherapy, simultaneously can weaken chemical therapy toxic side effect, make the patient reduce misery, improve life quality.

Claims (3)

1, treatment cancer in digestive system Chinese medicine preparation is characterized in that making with the raw material of Chinese medicine of following weight parts:
Herba Solani Nigri 10-30, Herba Solani Lyrati 15-30, Radix Actinidiae Chinensis 15-120, Caulis Marsdeniae Tenacissimae 10-60, Rhizoma Dioscoreae Bulbiferae 3-15, Herba Bidentis Bipinnatae 15-60, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 3-9, Endothelium Corneum Gigeriae Galli 3-9, Fructus Hordei Germinatus 10-30, Rhizoma Imperatae 10-30, Herba Lobeliae Chinensis 15-30.
2, treatment cancer in digestive system Chinese medicine preparation according to claim 1 is characterized in that making with the raw material of Chinese medicine of following weight parts:
Herba Solani Nigri 15-30, Herba Solani Lyrati 15-30, Radix Actinidiae Chinensis 30-60, Caulis Marsdeniae Tenacissimae 15-30, Rhizoma Dioscoreae Bulbiferae 3-15, Herba Bidentis Bipinnatae 15-60, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 3-9, Endothelium Corneum Gigeriae Galli 3-9, Fructus Hordei Germinatus 15-30, Rhizoma Imperatae 10-30, Herba Lobeliae Chinensis 15-30.
3, treatment cancer in digestive system Chinese medicine preparation according to claim 1 and 2 is characterized in that making with the raw material of Chinese medicine of following weight parts:
Herba Solani Nigri 20, Herba Solani Lyrati 20, Radix Actinidiae Chinensis 60, Caulis Marsdeniae Tenacissimae 30, Rhizoma Dioscoreae Bulbiferae 10, Herba Bidentis Bipinnatae 40, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus) 5, Endothelium Corneum Gigeriae Galli 5, Fructus Hordei Germinatus 15, Rhizoma Imperatae 20, Herba Lobeliae Chinensis 20.
CN2009100222203A 2009-04-28 2009-04-28 Chinese material medical preparation for treating esophagus cancer and gastric cancer of digestive system Expired - Fee Related CN101537144B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104162034A (en) * 2014-08-22 2014-11-26 许俊斋 Medicine for treating gastric cancer and preparation method thereof
WO2016094587A1 (en) * 2014-12-12 2016-06-16 Academia Sinica Use of polyacetylenic glycosides for suppression of granulocytic myeloid-derived suppressor cell activities and tumor metastasis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857557A (en) * 2006-03-13 2006-11-08 李万湖 Preparing process of Chinese medicine for treating stomach cancer and esophagus carcinoma

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104162034A (en) * 2014-08-22 2014-11-26 许俊斋 Medicine for treating gastric cancer and preparation method thereof
WO2016094587A1 (en) * 2014-12-12 2016-06-16 Academia Sinica Use of polyacetylenic glycosides for suppression of granulocytic myeloid-derived suppressor cell activities and tumor metastasis

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