CN101537090A - Pharmaceutical composition for treating lumbar intervertebral disc protrusion, preparation method and use thereof - Google Patents
Pharmaceutical composition for treating lumbar intervertebral disc protrusion, preparation method and use thereof Download PDFInfo
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- CN101537090A CN101537090A CN200910083093A CN200910083093A CN101537090A CN 101537090 A CN101537090 A CN 101537090A CN 200910083093 A CN200910083093 A CN 200910083093A CN 200910083093 A CN200910083093 A CN 200910083093A CN 101537090 A CN101537090 A CN 101537090A
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Abstract
The invention discloses a pharmaceutical composition which is effective in treating lumbar intervertebral disc protrusion. The pharmaceutical composition mainly comprises traditional Chinese herbal medicines, mainly including homalomena rhizome, harlequin glorybower leaf and twig, Chinese star jasmine, cynanchum paniculatum, erythrina indica lam, futokadsura stem, acanthopanax bark, wooly datchmanspipe herb, elecampane, aspongopus, tambac, fumitory and the like; the traditional Chinese herbal medicines are prepared by a regular method. The pharmaceutical composition has obvious healing effect for patients with various lumbar intervertebral disc protrusions; moreover, the pharmaceutical composition has short treatment course, small toxic-and-side effect, low price and low relapse rate after curing.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly a kind of pharmaceutical composition and its production and use with the effect of treatment prolapse of lumbar intervertebral disc.
Background technology
Prolapse of lumbar intervertebral disc is by the degeneration of lumbar intervertebral disc, vertebral pulp degeneration, so that prominent compressing rearward or stimulation spinal nerve root, or pass through a series of symptoms that the reflection of hole nervi vertebralis occurs.This disease is mainly in person between twenty and fifty, has waist to injure the chronic strain history outward more, and clinical the outbreak repeatedly with lumbago is cardinal symptom, shows as a side lumbago and to lower limb radiation more, the sick side limb obstacle of feeling.Doctor trained in Western medicine does not still have specificity to intervertebral disc prolapse treatment, intervertebral disc prolapse is mainly used treatments such as corticosteroid hormone and analgesic at present both at home and abroad, though can reach the effect of controlling symptoms, treatment cycle is long, and side effect greatly and uncertain therapeutic efficacy is cut.Operation is as a kind of method that solves such disease, and effect is also not satisfactory.
Prolapse of lumbar intervertebral disc should belong to the category of " pain along the spinal column " in motherland's traditional medicine, " lumbago and skelalgia ", and because of wound strain and insufficiency of kidney-YANG, vital essence is on the decline, and the muscle arteries and veins loses supports, wind-cold damp pathogen multiple abscess grain, and grain is stranded resistance, coagulation of QI-blood and falling ill.In " element is asked ", just mention: " belt vessel makes us lumbago, cannot pitching, face upward then and probably fall forward, weight lifting hinder waist ".Analyze the cause of disease of prolapse of lumbar intervertebral disc, mostly be the outer trauma that is subjected to, in have and lose empty or the damp etc. that is affected by the cold, be divided into types such as qi depression to blood stasis, wind chill blockage, the resistance of damp and hot numbness, caused by liver and kidney deficiency so distinguish its clinical syndrome.It is various to treat at present prolapse of lumbar intervertebral disc medicament categories commonly used clinically, but all effect is not quite fully up to expectations, and what have costs an arm and a leg, and the also toxic side effect that has brings very big inconvenience and misery to extensive patients.Therefore, the Chinese medicine of seeking a kind of effective treatment prolapse of lumbar intervertebral disc is one of important topic of current medical circle.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition with the effect of treatment prolapse of lumbar intervertebral disc; Another object of the present invention is to provide this preparation of drug combination method; The present invention also aims to provide the purposes of this pharmaceutical composition.
The present invention seeks to be achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
Rhizoma Homalomenae 10-40 weight portion Folium et Ramulus Clerodendri Trichotomi 10-30 weight portion
Caulis Trachelospermi 10-30 weight portion Radix Cynanchi Paniculati 10-30 weight portion
Cortex erythrinae 10-30 weight portion Caulis Piperis Kadsurae 10-30 weight portion
Cortex Acanthopancis 10-30 weight portion Herba Aristolochiae Mollissimae 10-30 weight portion
Radix Aucklandiae 6-20 weight portion Aspongopus 10-30 weight portion
Lignum Aquilariae Resinatum 6-30 weight portion Rhizoma Corydalis 10-40 weight portion
Squama Manis 6-30 weight portion Herba Artemisiae Anomalae 10-30 weight portion
Semen Persicae 10-30 weight portion Cornu Cervi Pantotrichum 3-20 weight portion
Herba Epimedii 6-30 weight portion Radix Zanthoxyli 6-20 weight portion
Radix Glycyrrhizae 6-20 weight portion.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Rhizoma Homalomenae 12 weight portion Folium et Ramulus Clerodendri Trichotomis 28 weight portions
Caulis Trachelospermi 12 weight portion Radix Cynanchi Paniculatis 28 weight portions
Cortex erythrinae 12 weight portion Caulis Piperis Kadsuraes 28 weight portions
Cortex Acanthopancis 12 weight portion Herba Aristolochiae Mollissimaes 28 weight portions
The Radix Aucklandiae 12 weight portion Aspongopuss 28 weight portions
Lignum Aquilariae Resinatum 8 weight portion Rhizoma Corydalis 38 weight portions
Squama Manis 8 weight portion Herba Artemisiae Anomalaes 28 weight portions
Semen Persicae 12 weight portion Cornu Cervi Pantotrichums 18 weight portions
Herba Epimedii 8 weight portion Radix Zanthoxylis 18 weight portions
Radix Glycyrrhizae 8 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Rhizoma Homalomenae 38 weight portion Folium et Ramulus Clerodendri Trichotomis 12 weight portions
Caulis Trachelospermi 12 weight portion Radix Cynanchi Paniculatis 28 weight portions
Cortex erythrinae 12 weight portion Caulis Piperis Kadsuraes 28 weight portions
Cortex Acanthopancis 12 weight portion Herba Aristolochiae Mollissimaes 28 weight portions
The Radix Aucklandiae 8 weight portion Aspongopuss 28 weight portions
Lignum Aquilariae Resinatum 8 weight portion Rhizoma Corydalis 38 weight portions
Squama Manis 8 weight portion Herba Artemisiae Anomalaes 28 weight portions
Semen Persicae 8 weight portion Cornu Cervi Pantotrichums 18 weight portions
Herba Epimedii 8 weight portion Radix Zanthoxylis 18 weight portions
Radix Glycyrrhizae 8 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Rhizoma Homalomenae 25 weight portion Folium et Ramulus Clerodendri Trichotomis 20 weight portions
Caulis Trachelospermi 20 weight portion Radix Cynanchi Paniculatis 20 weight portions
Cortex erythrinae 20 weight portion Caulis Piperis Kadsuraes 20 weight portions
Cortex Acanthopancis 20 weight portion Herba Aristolochiae Mollissimaes 20 weight portions
The Radix Aucklandiae 13 weight portion Aspongopuss 20 weight portions
Lignum Aquilariae Resinatum 18 weight portion Rhizoma Corydalis 25 weight portions
Squama Manis 18 weight portion Herba Artemisiae Anomalaes 20 weight portions
Semen Persicae 20 weight portion Cornu Cervi Pantotrichums 12 weight portions
Herba Epimedii 18 weight portion Radix Zanthoxylis 13 weight portions
Radix Glycyrrhizae 13 weight portions.
Get above-mentioned raw materials medicine pulverize separately and be ground into fine powder, add conventional adjuvant, according to common process, make acceptable forms clinically, comprise pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent etc.
Preparation of drug combination method of the present invention is:
Getting above-mentioned raw materials medicine pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 5-30 minute with clear water 400-800 parts by volume, fry in shallow oil with high heat to boiling, reuse 10-30 at a simmer minute, decoct 2-4 time, filter, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent etc. according to common process.
Preparation of drug combination method of the present invention is preferably:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 25 minutes with clear water 500 parts by volume, fry in shallow oil with high heat to boiling, 15 minutes at a simmer of reuse decocts 4 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent etc. according to common process.
Preparation of drug combination method of the present invention is preferably:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 10 minutes with clear water 700 parts by volume, fry in shallow oil with high heat to boiling, 25 minutes at a simmer of reuse decocts 2 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent etc. according to common process.
Preparation of drug combination method of the present invention is preferably:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 15 minutes with clear water 600 parts by volume, fry in shallow oil with high heat to boiling, with 20 minutes at a simmer, decoct 3 times, filter, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent etc. according to common process.
The ratio of weight portion of the present invention and parts by volume is g/ml;
Think that according to theory of Chinese medical science prolapse of lumbar intervertebral disc is marked with the pass with long-term strain, wet the staying of affection of exogenous wind-cold, kidney governing bones, liver governing tendons, the attached bone of muscle, after the middle age, the Liver and kidney degradation, the no muscle hair bone of suffering from a deficiency of the kidney, deficiency of the liver is difficult nourishing muscle and tendon, caused by liver and kidney deficiency.Execute the principle of controlling according to differential diagnosis in tcm, the present invention is directed to a large amount of cases of the comprehensive clinical practice of the various causes of disease of prolapse of lumbar intervertebral disc, developed the Chinese medicine pharmaceutical composition of treatment prolapse of lumbar intervertebral disc, its short treating period, evident in efficacy, toxic and side effects is little, cheap, relapse rate is low after curing.
Following experimental example is used to further specify but is not limited to the present invention.
The clinical observation of experimental example medicine composite for curing prolapse of lumbar intervertebral disc of the present invention
The present invention is through applicant's clinical practice embodiment 1 treatment patients with lumbar disc herniation 150 people.Take through 150 routine patients and to show that this pharmaceutical composition pushes away disc herniation to the treatment waist good curative effect.129 people that wherein fully recover, 15 people that take a turn for the better, invalid 6 people, total effective rate is 96%, and cure rate is 86%, and invalid is 4%.The criterion of therapeutical effect of observing is carried out according to the criterion of therapeutical effect of Ministry of Public Health promulgation.
Before the treatment, each case all pushes away scanning and X-ray pushes away positive profile according to waist through the CT waist, confirms that waist pushes away the outstanding and waist of intercalated disc and pushes away intercalated disc and give prominence to the position.
The criterion of curative effect:
Recovery from illness: functional rehabilitation is normal, and symptom all disappears.
Effectively: function is recovered normally substantially, and symptom is complete obiteration not.
Invalid: symptom does not change.
Model case:
Case one:
Name: Wu Xiangming, sex: man, age: 38 years old
Native place: Jingning County Wei Rong town Wei Rong people from village, name family: the Chinese, occupation: peasant
Consultation time: June nineteen ninety-five
The main suit: be diagnosed as prolapse of lumbar intervertebral disc in County Hospital, behind the medicines such as oral ibuprofen, unsatisfactory curative effect shows as lumbago, and the right lower extremity numbness increases the weight of during the cough sneeze.Basic disability.
Diagnosis: the Jingning County hospital diagnosis is a prolapse of lumbar intervertebral disc.
Medication: take the pharmaceutical composition one month that our embodiment 1 prepares.
Therapeutic effect: lumbago obviously alleviates, and the numbness of lower limbs transference cure can bend over to do light work, obey January again after, clinical symptoms all disappears, what work of private prosecution can both have been done, and again need not worry, and follows up a case by regular visits to so far recurrence yet, CT examination is normal.
Case two:
Name: Ma Xiaoning, sex: man, age: 30 years old
The native place: the Longde County connection is the village people, name family: the Chinese, occupation: driver
Consultation time: in October, 2002
Diagnosis: x-ray is a prolapse of lumbar intervertebral disc,
The main suit: the symptom of sleeping behind the hardboard bed first quarter moon of being in is alleviated a little, but can not be engaged in one's work, and the diagnosis and treatment of coming upon somebody's introduction, private prosecution once had the waist wound to make, and showed as lumbago, the right lower extremity numbness, and following waist tenderness is obvious, and radiates to the Ipsilateral lower limb.
Medication: take the pharmaceutical composition three months that embodiment 2 prepares.
Therapeutic effect: all clinical symptoms all disappear, and private prosecution can be run also and can have been jumped, and saying nothing of is to have driven, and follow up a case by regular visits to so far not recurrence, now fully recover, and CT examination is normal.
Case three:
Name: Zhang Guowen, sex: man, age: 40 years old
Native place: Jingning County Wei Rong town Wei Rong people from village, name family: the Chinese, occupation: certain local police station's supervisor
Consultation time: in March, 2007
Diagnosis: CT is diagnosed as prolapse of lumbar intervertebral disc
The main suit: undergo various treatments, curative effect is not all achieved one's goal, and causes to ask for leave often and delay one's work, and worries to the utmost point.
Medication: the medicine composite for curing for preparing with embodiment 3 two months.
Therapeutic effect: clinical symptoms is basic all to disappear, and continues to take the normal working of fully recover after January of embodiment one described medicine, and any task and skills training that can participant, recovers normal function, recurs yet so far, now fully recovers.
Following embodiment all can realize the effect of above-mentioned experimental example.
The specific embodiment
Embodiment 1: the preparation of pill
Rhizoma Homalomenae 15g Folium et Ramulus Clerodendri Trichotomi 25g Caulis Trachelospermi 15g Radix Cynanchi Paniculati 25g
Cortex erythrinae 15g Caulis Piperis Kadsurae 25g Cortex Acanthopancis 15g Herba Aristolochiae Mollissimae 25g
Radix Aucklandiae 8g Aspongopus 25g Lignum Aquilariae Resinatum 8g Rhizoma Corydalis 35g
Squama Manis 8g Herba Artemisiae Anomalae 25g Semen Persicae 15g Cornu Cervi Pantotrichum 15g
Herba Epimedii 8g Radix Zanthoxyli 15g Radix Glycyrrhizae 8g
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 10 minutes with clear water 750ml, fry in shallow oil with high heat to boiling, 25 minutes at a simmer of reuse decocts 2 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill according to common process.
Embodiment 2: the preparation of capsule
Rhizoma Homalomenae 12g Folium et Ramulus Clerodendri Trichotomi 28g Caulis Trachelospermi 12g Radix Cynanchi Paniculati 28g
Cortex erythrinae 12g Caulis Piperis Kadsurae 28g Cortex Acanthopancis 12g Herba Aristolochiae Mollissimae 28g
Radix Aucklandiae 12g Aspongopus 28g Lignum Aquilariae Resinatum 8g Rhizoma Corydalis 38g
Squama Manis 8g Herba Artemisiae Anomalae 28g Semen Persicae 12g Cornu Cervi Pantotrichum 18g
Herba Epimedii 8g Radix Zanthoxyli 18g Radix Glycyrrhizae 8g
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 10 minutes with clear water 600ml, fry in shallow oil with high heat to boiling, 30 minutes at a simmer of reuse decocts 2 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable capsule according to common process.
Embodiment 3: the preparation of tablet
Rhizoma Homalomenae 25g Folium et Ramulus Clerodendri Trichotomi 20g Caulis Trachelospermi 20g Radix Cynanchi Paniculati 20g
Cortex erythrinae 20g Caulis Piperis Kadsurae 20g Cortex Acanthopancis 20g Herba Aristolochiae Mollissimae 20g
Radix Aucklandiae 13g Aspongopus 20g Lignum Aquilariae Resinatum 18g Rhizoma Corydalis 25g
Squama Manis 18g Herba Artemisiae Anomalae 20g Semen Persicae 20g Cornu Cervi Pantotrichum 12g
Herba Epimedii 18g Radix Zanthoxyli 13g Radix Glycyrrhizae 13g
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 18 minutes with clear water 600ml, fry in shallow oil with high heat to boiling, 20 minutes at a simmer of reuse decocts 3 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable tablet according to common process.
Embodiment 4: the preparation of oral liquid
Rhizoma Homalomenae 20g Folium et Ramulus Clerodendri Trichotomi 25g Caulis Trachelospermi 15g Radix Cynanchi Paniculati 25g
Cortex erythrinae 15g Caulis Piperis Kadsurae 25g Cortex Acanthopancis 15g Herba Aristolochiae Mollissimae 25g
Radix Aucklandiae 12g Aspongopus 15g Lignum Aquilariae Resinatum 15g Rhizoma Corydalis 28g
Squama Manis 15g Herba Artemisiae Anomalae 25g Semen Persicae 15g Cornu Cervi Pantotrichum 15g
Herba Epimedii 15g Radix Zanthoxyli 15g Radix Glycyrrhizae 12g
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 20 minutes with clear water 500ml, fry in shallow oil with high heat to boiling, 20 minutes at a simmer of reuse decocts 3 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable oral liquid according to common process.
Embodiment 5: the preparation of unguentum
Rhizoma Homalomenae 12g Folium et Ramulus Clerodendri Trichotomi 28g Caulis Trachelospermi 12g Radix Cynanchi Paniculati 28g
Cortex erythrinae 12g Caulis Piperis Kadsurae 28g Cortex Acanthopancis 12g Herba Aristolochiae Mollissimae 28g
Radix Aucklandiae 10g Aspongopus 28g Lignum Aquilariae Resinatum 10g Rhizoma Corydalis 38g
Squama Manis 10g Herba Artemisiae Anomalae 28g Semen Persicae 12g Cornu Cervi Pantotrichum 18g
Herba Epimedii 10g Radix Zanthoxyli 18g Radix Glycyrrhizae 10g
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 6 minutes with clear water 700ml, fry in shallow oil with high heat to boiling, 30 minutes at a simmer of reuse decocts 2 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable unguentum according to common process.
Embodiment 6: the preparation of granule
Rhizoma Homalomenae 12g Folium et Ramulus Clerodendri Trichotomi 28g Caulis Trachelospermi 12g Radix Cynanchi Paniculati 28g
Cortex erythrinae 12g Caulis Piperis Kadsurae 28g Cortex Acanthopancis 12g Herba Aristolochiae Mollissimae 28g
Radix Aucklandiae 10g Aspongopus 28g Lignum Aquilariae Resinatum 10g Rhizoma Corydalis 38g
Squama Manis 10g Herba Artemisiae Anomalae 28g Semen Persicae 12g Cornu Cervi Pantotrichum 18g
Herba Epimedii 10g Radix Zanthoxyli 18g Radix Glycyrrhizae 10g
Get the above-mentioned raw materials medicine, add conventional adjuvant,, make granule according to common process.
Embodiment 7: the preparation of slow releasing agent
Rhizoma Homalomenae 10g Folium et Ramulus Clerodendri Trichotomi 30g Caulis Trachelospermi 10g Radix Cynanchi Paniculati 30g
Cortex erythrinae 10g Caulis Piperis Kadsurae 30g Cortex Acanthopancis 10g Herba Aristolochiae Mollissimae 30g
Radix Aucklandiae 10g Aspongopus 30g Lignum Aquilariae Resinatum 10g Rhizoma Corydalis 38g
Squama Manis 10g Herba Artemisiae Anomalae 28g Semen Persicae 10g Cornu Cervi Pantotrichum 20g
Herba Epimedii 10g Radix Zanthoxyli 20g Radix Glycyrrhizae 10g
Get the above-mentioned raw materials medicine, add conventional adjuvant,, make slow releasing agent according to common process.
Embodiment 8: the preparation of drop pill
Rhizoma Homalomenae 16g Folium et Ramulus Clerodendri Trichotomi 26g Caulis Trachelospermi 16g Radix Cynanchi Paniculati 26g
Cortex erythrinae 16g Caulis Piperis Kadsurae 26g Cortex Acanthopancis 16g Herba Aristolochiae Mollissimae 26g
Radix Aucklandiae 10g Aspongopus 26g Lignum Aquilariae Resinatum 10g Rhizoma Corydalis 36g
Squama Manis 10g Herba Artemisiae Anomalae 26g Semen Persicae 10g Cornu Cervi Pantotrichum 16g
Herba Epimedii 10g Radix Zanthoxyli 16g Radix Glycyrrhizae 10g
Get the above-mentioned raw materials medicine, add conventional adjuvant,, make drop pill according to common process.
Claims (10)
1, a kind of pharmaceutical composition with treatment prolapse of lumbar intervertebral disc is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Homalomenae 10-40 weight portion Folium et Ramulus Clerodendri Trichotomi 10-30 weight portion
Caulis Trachelospermi 10-30 weight portion Radix Cynanchi Paniculati 10-30 weight portion
Cortex erythrinae 10-30 weight portion Caulis Piperis Kadsurae 10-30 weight portion
Cortex Acanthopancis 10-30 weight portion Herba Aristolochiae Mollissimae 10-30 weight portion
Radix Aucklandiae 6-20 weight portion Aspongopus 10-30 weight portion
Lignum Aquilariae Resinatum 6-30 weight portion Rhizoma Corydalis 10-40 weight portion
Squama Manis 6-30 weight portion Herba Artemisiae Anomalae 10-30 weight portion
Semen Persicae 10-30 weight portion Cornu Cervi Pantotrichum 3-20 weight portion
Herba Epimedii 6-30 weight portion Radix Zanthoxyli 6-20 weight portion
Radix Glycyrrhizae 6-20 weight portion.
2, pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Homalomenae 12 weight portion Folium et Ramulus Clerodendri Trichotomis 28 weight portions
Caulis Trachelospermi 12 weight portion Radix Cynanchi Paniculatis 28 weight portions
Cortex erythrinae 12 weight portion Caulis Piperis Kadsuraes 28 weight portions
Cortex Acanthopancis 12 weight portion Herba Aristolochiae Mollissimaes 28 weight portions
The Radix Aucklandiae 12 weight portion Aspongopuss 28 weight portions
Lignum Aquilariae Resinatum 8 weight portion Rhizoma Corydalis 38 weight portions
Squama Manis 8 weight portion Herba Artemisiae Anomalaes 28 weight portions
Semen Persicae 12 weight portion Cornu Cervi Pantotrichums 18 weight portions
Herba Epimedii 8 weight portion Radix Zanthoxylis 18 weight portions
Radix Glycyrrhizae 8 weight portions.
3, pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Homalomenae 38 weight portion Folium et Ramulus Clerodendri Trichotomis 12 weight portions
Caulis Trachelospermi 12 weight portion Radix Cynanchi Paniculatis 28 weight portions
Cortex erythrinae 12 weight portion Caulis Piperis Kadsuraes 28 weight portions
Cortex Acanthopancis 12 weight portion Herba Aristolochiae Mollissimaes 28 weight portions
The Radix Aucklandiae 8 weight portion Aspongopuss 28 weight portions
Lignum Aquilariae Resinatum 8 weight portion Rhizoma Corydalis 38 weight portions
Squama Manis 8 weight portion Herba Artemisiae Anomalaes 28 weight portions
Semen Persicae 8 weight portion Cornu Cervi Pantotrichums 18 weight portions
Herba Epimedii 8 weight portion Radix Zanthoxylis 18 weight portions
Radix Glycyrrhizae 8 weight portions.
4, pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Rhizoma Homalomenae 25 weight portion Folium et Ramulus Clerodendri Trichotomis 20 weight portions
Caulis Trachelospermi 20 weight portion Radix Cynanchi Paniculatis 20 weight portions
Cortex erythrinae 20 weight portion Caulis Piperis Kadsuraes 20 weight portions
Cortex Acanthopancis 20 weight portion Herba Aristolochiae Mollissimaes 20 weight portions
The Radix Aucklandiae 13 weight portion Aspongopuss 20 weight portions
Lignum Aquilariae Resinatum 18 weight portion Rhizoma Corydalis 25 weight portions
Squama Manis 18 weight portion Herba Artemisiae Anomalaes 20 weight portions
Semen Persicae 20 weight portion Cornu Cervi Pantotrichums 12 weight portions
Herba Epimedii 18 weight portion Radix Zanthoxylis 13 weight portions
Radix Glycyrrhizae 13 weight portions.
5, as the arbitrary described pharmaceutical composition of claim 1-4, it is characterized in that getting this pharmaceutical composition crude drug, add conventional adjuvant, according to common process, make acceptable forms clinically: pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent.
6, as the arbitrary described preparation of drug combination method of claim 1-4, it is characterized in that this method is:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 5-30 minute with clear water 400-800 parts by volume, fry in shallow oil with high heat to boiling, reuse 10-30 at a simmer minute, decoct 2-4 time, filter, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent according to common process.
7, preparation of drug combination method as claimed in claim 6 is characterized in that this method is:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 25 minutes with clear water 500 parts by volume, fry in shallow oil with high heat to boiling, 15 minutes at a simmer of reuse decocts 4 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent according to common process.
8, preparation of drug combination method as claimed in claim 6 is characterized in that this method is:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 10 minutes with clear water 700 parts by volume, fry in shallow oil with high heat to boiling, 25 minutes at a simmer of reuse decocts 2 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent according to common process.
9, preparation of drug combination method as claimed in claim 6 is characterized in that this method is:
Getting the crude drug pulverize separately is ground into fine powder and sieves, mix by proportioning, in the gauze bag of packing into, soaked 15 minutes with clear water 600 parts by volume, fry in shallow oil with high heat to boiling, 20 minutes at a simmer of reuse decocts 3 times, filters, medicinal liquid merges, add conventional adjuvant,, make clinical or pharmaceutically acceptable pill, capsule, drop pill, tablet, granule, soft capsule, slow releasing agent, oral liquid, freeze-dried powder preparation or external plaster agent according to common process.
10, as the application of the arbitrary described pharmaceutical composition of claim 1-4 in preparation treatment prolapse of lumbar intervertebral disc medicine.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100830938A CN101537090B (en) | 2009-04-30 | 2009-04-30 | Pharmaceutical composition for treating lumbar intervertebral disc protrusion, preparation method and use thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100830938A CN101537090B (en) | 2009-04-30 | 2009-04-30 | Pharmaceutical composition for treating lumbar intervertebral disc protrusion, preparation method and use thereof |
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| CN101537090A true CN101537090A (en) | 2009-09-23 |
| CN101537090B CN101537090B (en) | 2012-05-23 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266512A (en) * | 2010-06-02 | 2011-12-07 | 张文录 | Medicine for treating bone diseases |
| CN103191343A (en) * | 2013-03-31 | 2013-07-10 | 董光宇 | Pharmaceutical composition for treating diaphyseal aclasis |
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2009
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102266512A (en) * | 2010-06-02 | 2011-12-07 | 张文录 | Medicine for treating bone diseases |
| CN102266512B (en) * | 2010-06-02 | 2014-07-16 | 张文录 | Medicine for treating bone diseases |
| CN103191343A (en) * | 2013-03-31 | 2013-07-10 | 董光宇 | Pharmaceutical composition for treating diaphyseal aclasis |
| CN103191343B (en) * | 2013-03-31 | 2015-04-08 | 董光宇 | Pharmaceutical composition for treating diaphyseal aclasis |
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| Publication number | Publication date |
|---|---|
| CN101537090B (en) | 2012-05-23 |
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