CN107184936A - Treat pharmaceutical composition of the cancer of the brain and preparation method thereof - Google Patents
Treat pharmaceutical composition of the cancer of the brain and preparation method thereof Download PDFInfo
- Publication number
- CN107184936A CN107184936A CN201710416246.0A CN201710416246A CN107184936A CN 107184936 A CN107184936 A CN 107184936A CN 201710416246 A CN201710416246 A CN 201710416246A CN 107184936 A CN107184936 A CN 107184936A
- Authority
- CN
- China
- Prior art keywords
- parts
- grams
- radix
- cancer
- brain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 30
- 208000003174 Brain Neoplasms Diseases 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 67
- 239000000203 mixture Substances 0.000 claims abstract description 25
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 13
- 244000061520 Angelica archangelica Species 0.000 claims abstract description 12
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 12
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 12
- 235000014375 Curcuma Nutrition 0.000 claims abstract description 12
- 244000164480 Curcuma aromatica Species 0.000 claims abstract description 12
- 240000009138 Curcuma zedoaria Species 0.000 claims abstract description 12
- 235000003405 Curcuma zedoaria Nutrition 0.000 claims abstract description 12
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 12
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 12
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 12
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 12
- 235000001287 Guettarda speciosa Nutrition 0.000 claims abstract description 12
- 239000009636 Huang Qi Substances 0.000 claims abstract description 12
- 241000112528 Ligusticum striatum Species 0.000 claims abstract description 12
- 244000197580 Poria cocos Species 0.000 claims abstract description 12
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 12
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 12
- 240000007164 Salvia officinalis Species 0.000 claims abstract description 12
- 239000001812 curcuma zedoaria berg. rosc. Substances 0.000 claims abstract description 12
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims abstract description 12
- 235000005412 red sage Nutrition 0.000 claims abstract description 12
- 235000019509 white turmeric Nutrition 0.000 claims abstract description 12
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 11
- 241000132012 Atractylodes Species 0.000 claims abstract description 11
- 241000756943 Codonopsis Species 0.000 claims abstract description 11
- 241000218176 Corydalis Species 0.000 claims abstract description 11
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 11
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 11
- 235000003805 Musa ABB Group Nutrition 0.000 claims abstract description 11
- 240000008790 Musa x paradisiaca Species 0.000 claims abstract description 11
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 11
- 235000015266 Plantago major Nutrition 0.000 claims abstract description 11
- 240000008488 Thlaspi arvense Species 0.000 claims abstract description 10
- 235000008214 Thlaspi arvense Nutrition 0.000 claims abstract description 10
- 239000007788 liquid Substances 0.000 claims description 18
- 210000003734 kidney Anatomy 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 12
- 239000003826 tablet Substances 0.000 claims description 7
- 239000002775 capsule Substances 0.000 claims description 6
- 239000008187 granular material Substances 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 5
- 230000003014 reinforcing effect Effects 0.000 claims description 5
- 241000411851 herbal medicine Species 0.000 claims description 4
- 230000001737 promoting effect Effects 0.000 claims description 4
- 210000000952 spleen Anatomy 0.000 claims description 4
- 210000002784 stomach Anatomy 0.000 claims description 4
- 244000170916 Paeonia officinalis Species 0.000 claims description 3
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 3
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000007938 effervescent tablet Substances 0.000 claims description 3
- 244000025254 Cannabis sativa Species 0.000 claims description 2
- 230000017531 blood circulation Effects 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 235000015067 sauces Nutrition 0.000 claims description 2
- 241000196324 Embryophyta Species 0.000 claims 1
- 239000002398 materia medica Substances 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract description 39
- 229940079593 drug Drugs 0.000 abstract description 29
- 208000002193 Pain Diseases 0.000 abstract description 25
- 230000036407 pain Effects 0.000 abstract description 25
- 230000000694 effects Effects 0.000 abstract description 18
- 201000010099 disease Diseases 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 11
- 231100000331 toxic Toxicity 0.000 abstract description 8
- 230000002588 toxic effect Effects 0.000 abstract description 8
- 208000024891 symptom Diseases 0.000 abstract description 3
- 238000007917 intracranial administration Methods 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 21
- 238000007654 immersion Methods 0.000 description 10
- 230000036541 health Effects 0.000 description 8
- 235000012054 meals Nutrition 0.000 description 8
- 231100000614 poison Toxicity 0.000 description 8
- 230000035939 shock Effects 0.000 description 8
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 238000002512 chemotherapy Methods 0.000 description 7
- 239000002574 poison Substances 0.000 description 7
- 238000002560 therapeutic procedure Methods 0.000 description 7
- 230000036592 analgesia Effects 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 206010007247 Carbuncle Diseases 0.000 description 5
- 239000000284 extract Substances 0.000 description 5
- 241000255925 Diptera Species 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 201000009030 Carcinoma Diseases 0.000 description 3
- 206010010356 Congenital anomaly Diseases 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 206010052804 Drug tolerance Diseases 0.000 description 3
- 241000256856 Vespidae Species 0.000 description 3
- 230000002567 autonomic effect Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 208000001780 epistaxis Diseases 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 230000026781 habituation Effects 0.000 description 3
- 201000007227 lymph node tuberculosis Diseases 0.000 description 3
- 230000008520 organization Effects 0.000 description 3
- 210000001835 viscera Anatomy 0.000 description 3
- PPKXEPBICJTCRU-XMZRARIVSA-N (R,R)-tramadol hydrochloride Chemical compound Cl.COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 PPKXEPBICJTCRU-XMZRARIVSA-N 0.000 description 2
- 206010058019 Cancer Pain Diseases 0.000 description 2
- 244000301850 Cupressus sempervirens Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 description 2
- 206010061306 Nasopharyngeal cancer Diseases 0.000 description 2
- 206010053159 Organ failure Diseases 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 241000405414 Rehmannia Species 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 230000001079 digestive effect Effects 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 230000036449 good health Effects 0.000 description 2
- 230000011132 hemopoiesis Effects 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 201000011216 nasopharynx carcinoma Diseases 0.000 description 2
- 210000001154 skull base Anatomy 0.000 description 2
- 201000009032 substance abuse Diseases 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 229960003107 tramadol hydrochloride Drugs 0.000 description 2
- 201000008827 tuberculosis Diseases 0.000 description 2
- 235000020985 whole grains Nutrition 0.000 description 2
- 235000000832 Ayote Nutrition 0.000 description 1
- 244000036905 Benincasa cerifera Species 0.000 description 1
- 235000011274 Benincasa cerifera Nutrition 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 235000009854 Cucurbita moschata Nutrition 0.000 description 1
- 240000001980 Cucurbita pepo Species 0.000 description 1
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010019194 Head discomfort Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 235000002710 Ilex cornuta Nutrition 0.000 description 1
- 241001310146 Ilex cornuta Species 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 235000010326 Osmanthus heterophyllus Nutrition 0.000 description 1
- 241000013557 Plantaginaceae Species 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000001815 biotherapy Methods 0.000 description 1
- 230000001612 cachectic effect Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 239000000571 coke Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003958 fumigation Methods 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 239000000077 insect repellent Substances 0.000 description 1
- 210000001699 lower leg Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 235000015136 pumpkin Nutrition 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 231100000155 toxicity by organ Toxicity 0.000 description 1
- 230000007675 toxicity by organ Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 229940126673 western medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention is a kind of to treat pharmaceutical composition of the cancer of the brain and preparation method thereof, the pharmaceutical composition decoction that oral medicament composition is made up of Radix Codonopsis, Radix Angelicae Sinensis, the Radix Astragali, cultivated land, Chinese yam, matrimony vine, the bighead atractylodes rhizome, Poria cocos, radix scrophulariae, Divine Comedy, rhizoma zingiberis, Ligusticum wallichii, Rhizoma Sparganii, curcuma zedoary, safflower, peach kernel, pseudo-ginseng, field pennycress, marine alga, the red sage root, plantain seed, corydalis tuber, the root of Dahurain angelica treats the cancer of the brain, it can reach one left and right pain relief for oral administration, three doses or so pain of medication disappear, continuous use three months or so, can reduce intracranial tumors.The through focus of medicine can eliminate patient's focus pain and reduce intracranial tumors, reach the purpose of the treatment cancer of the brain, no obvious toxic-side effects.Overcome treatment cancer of the brain medicine at present cure the symptoms, not the disease, the not thorough, shortcoming of toxic side effect of ease pain.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for treating the cancer of the brain and preparation method thereof.
Background technology
Cancer is to endanger one of principal disease of human health most serious, is referred to as incurable disease.The maximum defect of radiotherapy be
Focus formation coke button, leaves the seed of trouble of recurrence.And the damage of normal structure is easily caused, limit that to give tumor tissues larger
Dosage, it is helpless to the case that has the transfer of potential amphi position.Chemotherapy good and evil are all damaged, and have whole body toxic side effect.Although interventional therapy
It is the progress of chemotherapy, the ratio that good and evil are all damaged, which has, significantly to be adjusted, it may be said that be local chemotherapy, although do not injure complete
Body, but the infringement to local internal organs organ is bigger, it is easy to cause organ toxicity's exhaustion.The greatest drawback of operative treatment has two:
One is the organic whole balance that human body is also destroyed when cutting carcinoma.Two be that the operation of cutting carcinoma is not unclean thorough, can be left
The seed of trouble of diffusion transfer at full speed, local diffusion and the transfer of potential amphi position to tumour are entirely possible to cause " to press cucurbit
The consequence of wooden dipper ".The greatest drawback of gene therapy is rather expensive.Biotherapy is invalid to immune fastness oncotherapy.
Current treatment by Chinese herbs overcomes the most of defect of the above, focuses on organic conception, diagnosis and treatment based on an overall analysis of the illness and the patient's condition.Existed however, combatting poison with poison
Toxic side effect, low dose of Chinese Herbs are slow, treat phase length and effect is unstable.So far there are no a kind of eliminate cancer pain and control
Treating autonomic drug, pharmaceutical composition of cancer and preparation method thereof is used for treating cancer.
Radix scrophulariae is the root of Scrophulariaceae herbaceos perennial radix scrophulariae, alias radix scrophulariae, black ginseng.Nature,taste and action:It is sweet, bitter, salty, micro-
Tremble with fear, enter lung, stomach, kidney channel.Nourishing Yin and falling fire, clearing heat and detoxicating, dissipating bind disappear carbuncle, control pyreticosis polydipsia, hair spot, hectic fever due to yin labor heat, night sleep it is not peaceful,
Spontaneous sweating, Tianjin hinder constipation, hematemesis and epistaxis, abscess of throat, carbuncle swells, scrofula.
The present invention focuses on reinforcing life power, strengthens the viable organism energy, and adjustment life organic whole balance is nourished congenital
Kidney water, the health care taste day after tomorrow.On the one hand function of human body work is coordinated, on the one hand through focus is assaulted fortified position;On the one hand take away the firewood under the cauldron, it is excellent
Change rehabilitation environment, on the one hand cancer cell is suffered a shock.Zhang Yuansu said, " radix scrophulariae is the agent of important department, and pipe is led above and below all gas, eliminate and
It is not turbid ".《Detailed outline》:" kidney water is injured, kidney-Yang fall, lonely sun unrooted, sends out as fiery disease, and method preferably strengthens water with fire processed, therefore radix scrophulariae and glutinous rehmannia
Same work(.Its scrofula that disappears also is to dissipate fire, and it is fiery disease that Liu, which keeps the truth tuberculosis,.”《Medicineization justice》:" the dirty empty then heat of kidney and it is dry, it is preferably cool to mend
It, this only cool profit nourshing kidney victory is known, cypress, specially for kidney monarch drug in a prescription.”《Herbal justice》:" radix scrophulariae is reported to the property of the moon, special main pyreticosis, bitter
Then drop-down is descending, therefore can control the diseases such as internal organs thermojunction.Taste is again pungent and micro- salty, therefore straight hematopoiesis point and logical blood stasis, also can layman in through tunnel,
And the carbuncle swells for the knot heat that dissipates.It is cold without high, profit and oiliness --- --- is more eased up, abuses difference is light.”《Records of Tradition Chinese and Western Medicine in Combination》:
" reused into Ziyingqingweitang also must with return in Siwu Tang Chinese herbaceous peony it is auxiliary it, this is so-called careful not to be mutually exclusive boldly and with confidence." radix scrophulariae energy is clearly
Fire removing toxic substances, softening and resolving hard mass.Softening hard masses of relieving inflammation or internal heat are gone directly focus, are taken away the firewood under the cauldron, cancer cell is suffered a shock, and deteriorate the living environment of cancer cell;
Detoxicating and resolving a mass goes directly focus, the cancer cell of shock is excluded external.The operative treatment destruction for overcoming current treating cancer is organic
Shortcoming that is overall and being easily caused amphi position transfer, overcomes the toxic side effect that chemicotherapy, interventional therapy and Chinese herbal medicine combat poison with poison and lacks
Point, overcome the steps analgesia methods of World Health Organization WHO tri- cure the symptoms, not the disease, not thorough, easy habituation of easing pain, toxic side effect
Shortcoming.
Usage and dosage:It is for oral administration:The money of decoct soup 3-5, or enter ball, dissipate.External application:Smash to apply or grind and dress.
This autonomic drug have the advantages that to exploit natural resources abundant, convenient sources, cost is relatively low, easy to spread.
Pharmaceutical composition of the present invention and my patented certificate in 2010 of application in 2005 " one kind eliminates pain caused by cancer and controlled
Treat autonomic drug of advanced cancer and preparation method thereof(ZL200510031917.9)" different, promoting blood circulationization is enhanced in original basis
The stasis of blood, Repercusion analgesia, tonifying kidney and promoting digestion spleen, the effect of softening and resolving hard mass, compensate for the deficiency of primary bright patent drug composition.
The content of the invention
It is an object of the invention to provide a kind of pharmaceutical composition for treating the cancer of the brain and preparation method thereof, overcome operation, put
Chemotherapy, interventional therapy and current Chinese herbal medicine deficiency for cancer, overcome the steps analgesia methods of World Health Organization WHO tri- and take stopgap measures and do not control
Originally, not thorough, the easy habituation of analgesia, the shortcoming of toxic side effect..
The purpose of the present invention is achieved through the following technical solutions:
A kind of therapy for treating the pharmaceutical composition of the cancer of the brain and preparation method thereof is mainly by the treatment side of oral medicament composition
Method.
The pharmaceutical composition parts by weight of raw materials component of the treatment cancer of the brain is 5-1000 parts of radix scrophulariae, 5-400 parts of Ligusticum wallichii, party
Ginseng 5-150 parts, 5-150 parts of Radix Angelicae Sinensis, 5-400 parts of the Radix Astragali, 5-200 parts of cultivated land, 5-300 parts of Chinese yam, 5-150 parts of matrimony vine,
5-200 parts of the bighead atractylodes rhizome, 5-150 parts of Poria cocos, 5-150 parts of Divine Comedy, 5-150 parts of rhizoma zingiberis, 5-300 parts of plantain seed, Rhizoma Sparganii 5-100
Part, 5-100 parts of curcuma zedoary, 5-100 parts of safflower, 5-100 parts of peach kernel, 5-100 parts of pseudo-ginseng, 5-500 parts of field pennycress, marine alga 5-
500 parts, 5-100 parts of the red sage root, 5-100 parts of corydalis tuber, 5-100 parts of the root of Dahurain angelica.
Preferably 50-800 parts of radix scrophulariae, 10-100 parts of Ligusticum wallichii, 10-50 parts of Radix Codonopsis, 5-50 parts of Radix Angelicae Sinensis, the Radix Astragali 5-100
Part, 10-100 parts of cultivated land, 10-150 parts of Chinese yam, 5-100 parts of matrimony vine, 10-100 parts of the bighead atractylodes rhizome, 5-50 parts of Poria cocos, Divine Comedy 5-
50 parts, 5-50 parts of rhizoma zingiberis, 5-100 parts of plantain seed, 10-50 parts of Rhizoma Sparganii, 10-50 parts of curcuma zedoary, 10-50 parts of safflower, peach kernel
10-50 parts, 10-50 parts of pseudo-ginseng, 10-100 parts of field pennycress, 10-100 parts of marine alga, 10-50 parts of the red sage root, corydalis tuber 10-50
Part, 10-50 parts of the root of Dahurain angelica.
Preferably 300 parts of radix scrophulariae, 50 parts of Ligusticum wallichii, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 60 parts of the Radix Astragali, 60 parts of cultivated land, Chinese yam 60
Part, 20 parts of matrimony vine, 60 parts of the bighead atractylodes rhizome, 20 parts of Poria cocos, 20 parts of rhizoma zingiberis, 30 parts of plantain seed, 20 parts of Rhizoma Sparganii, 20 parts of curcuma zedoary, 20 parts of safflower,
20 parts of peach kernel, 20 parts of pseudo-ginseng, 50 parts of field pennycress, 20 parts of marine alga, 20 parts of the red sage root, 10 parts of Divine Comedy, 20 parts of corydalis tuber, 20 parts of the root of Dahurain angelica.
The present invention is a kind of to treat pharmaceutical composition of the cancer of the brain and preparation method thereof, oral medicament composition by Radix Codonopsis, Radix Angelicae Sinensis,
The Radix Astragali, cultivated land, Chinese yam, matrimony vine, the bighead atractylodes rhizome, Poria cocos, radix scrophulariae, Divine Comedy, rhizoma zingiberis, Ligusticum wallichii, Rhizoma Sparganii, curcuma zedoary, safflower, peach kernel, pseudo-ginseng, lose
Sauce grass, marine alga, the red sage root, plantain seed, corydalis tuber, root of Dahurain angelica composition.
The preparation method of described pharmaceutical composition comprises the following steps:Take the component first to use cold water soak 30 minutes, use
Water is that water did not had medicine, and then decocting is mixed twice, and decocting time first time is 45 minutes after boiling, pours out first time decocting medicine
After liquid, add water not medicine.Second of decocting time is 30 minutes after boiling, and decoction mixing concentration is extracted in decocting twice is
400 milliliters, or prepared by medicament common method.
After the preparation method, in addition to the concentration of composition extract or medicinal extract, the method system for routinely preparing oral medicine
Standby oral medicine, wherein water decoction directly can take or be made oral liquid, can also add pharmaceutically available auxiliary material.
The medicament refers in any pharmacy described oral administered dosage form, refer in particular to granule, capsule,
Tablet(Containing effervescent tablet)And oral liquid, most preferably decoction.
A kind of specific implementation operating process for treating the pharmaceutical composition of the cancer of the brain and preparation method thereof of the present invention:Endo-medicine
Composition prescription water decoction or other oral administered dosage forms:Granule, capsule, tablet(Containing effervescent tablet)And oral liquid.
The pharmacology of pharmaceutical composition prescription of the present invention is:The component radix scrophulariae nourishing Yin and falling fire, clearing heat and detoxicating, cool blood are promoted the production of body fluid,
Softening and resolving hard mass disappears carbuncle, righting eliminating evil again, and eliminating evil is not hindered just, using it as monarch drug in a prescription;Radix Codonopsis, Radix Angelicae Sinensis, the Radix Astragali, cultivated land, Chinese yam, Chinese holly
Qi, the bighead atractylodes rhizome, Poria cocos, Divine Comedy invigorating the blood, tonifying kidney and promoting digestion spleen, strengthen the body resistance to consolidate the constitution, using it as ministerial drug;Ligusticum wallichii, Rhizoma Sparganii, curcuma zedoary, safflower,
Peach kernel, pseudo-ginseng, field pennycress, marine alga, the red sage root, plantain seed, corydalis tuber, the root of Dahurain angelica, activate blood circulation and disperse blood clots eliminating evil, using it as adjutant;Rhizoma zingiberis temperature
In by cold, Back to Yang Tongmai, using it to make medicine.
The present invention has the following effects and advantage:
1st, the pharmaceutical composition that the present invention is provided, its main component is radix scrophulariae.Its decocting, the steamed medicament for extracting preparation are taken, can
Treat the cancer of the brain.The present invention focuses on reinforcing life power, strengthens the organism energy, and adjustment life organic whole balance is nourished congenital
Kidney water, the health care taste day after tomorrow give full play to the eliminating evil strength of human body organism in itself.On the one hand function of human body work, one are coordinated
The through focus of aspect is assaulted fortified position;On the one hand take away the firewood under the cauldron, optimize rehabilitation environment, on the one hand cancer cell is suffered a shock.Radix scrophulariae Qinghuo Jiedu,
Softening and resolving hard mass.Softening hard masses of relieving inflammation or internal heat are gone directly focus, are taken away the firewood under the cauldron, cancer cell is suffered a shock, and deteriorate the living environment of cancer cell;Detoxicating and resolving a mass
Through focus, excludes the cancer cell of shock external.
2nd, the operative treatment destruction organic whole for overcoming current treating cancer and the shortcoming for being easily caused amphi position transfer, overcome and put
The toxic side effect shortcoming that chemotherapy, interventional therapy and Chinese herbal medicine are combatted poison with poison, overcomes the steps analgesia methods of World Health Organization WHO tri-
Cure the symptoms, not the disease, ease pain not thorough, easy habituation, the shortcoming of toxic side effect.
3rd, curative effect spy is good, no obvious toxic-side effects.
4th, case report
The direct oral medication cancer of the brain patient of pharmaceutical composition decoction 5, PRELIMINARY RESULTS brief summary is as follows:
1st, general information
1.1 case selection
In 5, nasopharyngeal carcinoma invades basis cranii, 2, slope, primary brain cancer 3.
1.2 sexes and age:
Man 1, female 4,50-60 years old 3,60-70 years old 2.
1.3 malignant tumour situations
Most typical patient is imperial XX, female, 52 years old, the villager of Hengyang, Hunan Province, and left eye is protruded, and face deformation, pain takes salt love song
Easing pain horse more.Drink medicine one one and take pain relief, drink the one rear pain of medicine and disappear, energy takes a turn for the better, and does not have during continuous medication
Pain.Continuous use CT checks in three months, tumor disappearance, patient is still living and in good health so far.
Oldest patient is 67 years old, and female, the villager of Hunan Hengnan County, pain is felt bad, oral medicament composition decoction
One rear pain disappears, after 20 doses of medication, and patient is because pain disappears, diet and energy take a turn for the better and accepted as unavoidable preferably, refusal
Drink medicine.There is head discomfort again in Second Year, and right hand right crus of diaphragm is numb, is unwilling to continue to drink medicine again after ten doses of medication.Like this, often
Year medication 20 days or so, 10 years so far, most serious is once 2016, is just ready to drink medicine to almost hemiplegia.
Nasopharyngeal carcinoma invades basis cranii, the patient on slope, male, 61 years old, and nosebleed epistaxis, headache, nostril is blocked, and takes tramadol hydrochloride town
Bitterly.The one rear pain of oral medicament composition decoction disappears, continuous medication compositions decoction 30 days, stool pull out yellow and
White bar is sprayed in green purulence group, nostril, diet and energy take a turn for the better.Compositions decoction continuously take medicine after 60 days,
Patient admission is discontinued, and finds not only not bitterly, and Everything is fine, is just again unwilling to drink medicine, also not checking is
It is no to cure, because heart infarction is dead after 3 years.
2nd, treatment method:
Medication compositions water decoction, one day one two clothes or three clothes, take orally, auf nuechternen Magen einnehmen injuring spleen-stomach after the meal first.
3rd, treatment results:
3.1st, after medication compositions water decoction, the one clothes of traditional Chinese medicine for oral administration, pain relief, after traditional Chinese medicine for oral administration one two takes, pain
Pain is completely eliminated, and energy takes a turn for the better.In addition to toxin expelling of suffering from diarrhoea, non-evident effect, effective percentage 100% after all patient's medications.
3.2nd, 5 clinical efficacies of pharmaceutical composition decoction are as follows:
Treat number of cases and alleviate pain caused by cancer(One clothes)Eliminate pain caused by cancer(One two clothes)Energy improvement recovery, which is taken care of oneself, to be carried
High quality of life band knurl, which is survived, cures
5 100% 100% 100% 100% 80% 20%
4th, discuss:
The present invention is a kind of to treat pharmaceutical composition of the cancer of the brain and preparation method thereof, mainly focuses on reinforcing life power, reinforcing life
The body energy is ordered, adjustment life organic whole balance nourishes congenital kidney water, the health care taste day after tomorrow.On the one hand function of human body is coordinated
Work, focus of on the one hand going directly is assaulted fortified position;On the one hand take away the firewood under the cauldron, optimize rehabilitation environment, on the one hand cancer cell is suffered a shock.Zhang Yuansu
Said, " radix scrophulariae is the agent of important department, and pipe is led above and below all gas, is eliminated without turbid ".《Detailed outline》:" kidney water is injured, kidney-Yang fall, lonely sun
Unrooted, sends out as fiery disease, and method preferably strengthen water with fire processed, therefore radix scrophulariae and the same work(of glutinous rehmannia.Its scrofula that disappears also is to dissipate fire, and Liu, which keeps the truth tuberculosis, is
Fiery disease.”《Medicineization justice》:" the dirty empty then heat of kidney and it is dry, suitable cool benefits, solely this cool profit nourshing kidney win know, cypress, specially for kidney monarch
Medicine.”《Herbal justice》:" radix scrophulariae is reported to the property of the moon, special main pyreticosis, and then drop-down is descending for bitter, therefore can control the diseases such as internal organs thermojunction.Taste
It is again pungent and micro- salty, therefore straight hematopoiesis point and logical blood stasis, also can layman in through tunnel, and carbuncle swells for the knot heat that dissipates.It is cold without high, profit without
Greasy --- --- is more eased up, and abuses difference is light.”《Records of Tradition Chinese and Western Medicine in Combination》:" being reused into Ziyingqingweitang also must be with Siwu Tang
Return Chinese herbaceous peony it is auxiliary it, this is so-called careful not to be mutually exclusive boldly and with confidence.”
Radix scrophulariae energy cool blood is promoted the production of body fluid, kidney is supported in enriching yin, the system that expels the heat-evil fire, detoxication and toxicant eliminating function, be the reason for cancer pain accumulate in fiery poison, deficiency of Yin fire
Prosperous, blood-head body fluid deficiency, the radix scrophulariae efficacy of a drug once works, and effect is just as fire-fighting fire extinguishing, quickly not bitterly, here it is " strong water with
The contribution of system fire ".Why can softening hard masses disappear carcinoma, its main cause can neutralize focus cancer cell and depend on for existence and active
Sour environment, makes the living environment alkalization of cancer cell.The living environment of cancer cell is namely degrading, is conducive to normal health
Cells survival develops.Acid helps fire, cancer cell acidophilus, once living environment alkalization, cancer cell is just gone into a coma shock.
Radix scrophulariae is cold and cool medicine, and amount is small not to work, and measures big patient and does not bear.So, pharmaceutical composition can just rise
Act on.It is the neutralization of the cold property of medicine of temperature first, neutralizes cold and cool.
Our curing cancers Jiang Ai roads doctrines!Not killing cancer cell!We are compared to tumour ant bag and hornet in mountain forest
Nest, we do not touch it, and ant, a hornet all do not see, once touching, ant, hornet will run fast everywhere, Take me as I am
Curing cancers must first righting the reason for.Also we are compared to cancer cell the mosquito of summer and autumn, and we kill without mosquito-repellent incense
Mosquito less sprays mosquito with agricultural chemicals, and our method is:First open door and window and use straw tangerine bar sootiness again, when mosquito all goes out
Go just to extinguish fumigation torch, even if shutting screen window and door is settled!
5th, conclusion
The present invention is a kind of to treat pharmaceutical composition of the cancer of the brain and preparation method thereof, effective percentage 100%, and curative effect is rapidly, short treating period,
Non-evident effect, is the choice drug for quite preferably treating the cancer of the brain.However, the present invention is to taste after chemotherapy and interventional therapy
The patient of the cold of insufficiency type and organ failure, digestive function exhaustion person are invalid.
6th, points for attention
The patient of constitution preference can the explanation of book as directed normally take medicine compositions, must suffer from diarrhoea toxin expelling, abdomen during medication
Rush down not wound body.
7th, avoid
The present invention is disabled to cachectic patients caused by chemotherapy and interventional therapy and organ failure, digestive function exhaustion person, to spleen
The suitable cold of insufficiency type of stomach, big loose stool and lets out, stomach Qi disables exhausted patient before medication, avoid during traditional Chinese medicine for oral administration pan-fried, the fried, cooked food of clothes and
Wax gourd, pumpkin etc. are sent out rotten and help Collapse ulcer foods, avoid eating sour food.
A kind of pharmaceutical composition for treating the cancer of the brain of the present invention can not be with other Chinese and Western medicines while using.
Model case 1
Imperial XX, female, 52 years old, the villager of Hengyang, Hunan Province, left eye was protruded, face deformation, and pain takes tramadol hydrochloride analgesia.Drink medicine
One one takes pain relief, drinks the one rear pain of medicine and disappears, energy takes a turn for the better, and does not have pain during continuous medication.Continuous use
CT checks in three months, tumor disappearance, patient is still living and in good health so far.
Model case 2
Liu XX, 67 years old, female, the villager of Hunan Hengnan County, pain was felt bad, and the one rear pain of oral medicament composition decoction disappears,
Take medicine after 20 doses, patient is because pain disappears, diet and energy take a turn for the better and accepted as unavoidable preferably, and refusal drinks medicine.Second Year goes out again
Existing head is uncomfortable, and right hand right crus of diaphragm is numb, is unwilling to continue to drink medicine again after ten doses of medication.Like this, 20 days left sides of annual medication
The right side, 10 years so far, most serious is once 2016, is just ready to drink medicine to almost hemiplegia.
Model case 3
Cao's ××, male, 63 years old, the villager of Hunan Yongxing County was looked into and invades basis cranii, slope for nasopharyngeal carcinoma, and ala magna ossis sphenoidalis sclerotin is broken
Bad, headache, bleeding from five sense organs or subcutaneous tissue are quite serious.Lymthoma is multiple on neck, two nostrils have been blocked, and dry larynx is dry, vexed and hot-tempered, and salt is leaned on before medication
Sour C16H25NO2 analgesia, hospital notifies to prepare funeral affairs.One less than one hour pain of a clothes of taking medicine is eliminated, after ten doses of medication, from two
Nostril comes out strip slough, and double nasal respirations are unobstructed, during medication, does not occur nosebleed epistaxis, and lymthoma reduces.
Model case 4
Lee XX, man, 61 years old, nasopharyngeal carcinoma invaded basis cranii, the patient on slope, and nosebleed epistaxis, headache, nostril is blocked, and takes tramadol hydrochloride town
Bitterly.The one rear pain of oral medicament composition decoction disappears, continuous medication compositions decoction 30 days, stool pull out yellow and
White bar is sprayed in green purulence group, nostril, diet and energy take a turn for the better.Compositions decoction continuously take medicine after 60 days,
Patient admission is discontinued, and finds not only not bitterly, and Everything is fine, is just again unwilling to drink medicine, also not checking is
It is no to cure, because heart infarction is dead after 3 years.
5th, embodiment
Embodiment 1
Pharmaceutical composition decoction of the present invention
Get it filled and collect immersion liquid after compositions, plus constant decocting, add water and be repeated once pan-fried, immersion liquid mixing bottling, cancer patient
Take in two times after meal daily.
Embodiment 2
Drug composition oral liquid of the present invention
Get it filled and collect immersion liquid after compositions, plus constant decocting, add water and be repeated once pan-fried, immersion liquid mixing concentration, routinely make
Into oral liquid bottling, cancer patient takes in two times after meal daily.
Embodiment 3
Medicament composition capsule agent of the present invention
Get it filled and collect immersion liquid after compositions, plus constant decocting, add water and be repeated once pan-fried, immersion liquid mixing is condensed into medicinal extract, makes
20 mesh of grain, it is encapsulated, capsule is made, every 0.4 gram of capsule is 10 grams of crude drug.Cancer patient takes in three times after meal daily, often
Secondary 10, take in two times after meal daily, 15 every time.
Embodiment 4
Medicinal composition tablets of the present invention
Get it filled and collect immersion liquid after compositions, plus the decocting of constant, add water and be repeated once pan-fried, immersion liquid mixing is condensed into medicinal extract,
The mesh of whole grain 20, tabletting is made tablet, and every 0.4 gram is containing 10 grams of crude drug.Cancer patient takes in two times after meal daily, and every time 15
Piece, takes in three times after meal daily, and 10 tablets once.
Embodiment 5
Medicament composition granule agent of the present invention
Get it filled and collect immersion liquid after compositions, plus the decocting of constant, add water and be repeated once pan-fried, immersion liquid mixing is condensed into medicinal extract,
The mesh of whole grain 20, into granule.It is containing 100 grams of crude drug often to wrap 10 grams.Cancer patient takes in two times after meal daily, every time 1.5 bag, often
It takes in three times, every time 1 bag.
Drug composition oral liquid of the present invention, granule, tablet implementation mode of operation ibid.
Claims (8)
1. a kind of pharmaceutical composition for treating the cancer of the brain, mainly by radix scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Radix Astragali, cultivated land, Chinese yam, matrimony vine, white
Art, Poria cocos, Divine Comedy, rhizoma zingiberis, Ligusticum wallichii, Rhizoma Sparganii, curcuma zedoary, safflower, peach kernel, pseudo-ginseng, field pennycress, marine alga, the red sage root, plantain seed, prolong recklessly
Rope, the root of Dahurain angelica or the preparation that can be pharmaceutically prepared from auxiliary material.
2. according to a kind of pharmaceutical composition for treating the cancer of the brain of the requirement 1 of right, the medicine is following raw material component:
5-1000 grams of radix scrophulariae, 5-400 grams of Ligusticum wallichii, 5-150 grams of Radix Codonopsis, 5-150 grams of Radix Angelicae Sinensis, 5-400 grams of the Radix Astragali, cultivated land 5-200
Gram, 5-300 grams of Chinese yam, 5-150 grams of matrimony vine, 5-200 grams of the bighead atractylodes rhizome, 5-150 grams of Poria cocos, 5-150 grams of Divine Comedy, rhizoma zingiberis 5-
150 grams, 5-300 grams of plantain seed, 5-100 grams of Rhizoma Sparganii, 5-100 grams of curcuma zedoary, 5-100 grams of safflower, 5-100 grams of peach kernel, pseudo-ginseng
5-100 grams, 5-500 grams of field pennycress, 5-500 grams of marine alga, 5-100 grams of the red sage root, 5-100 grams of corydalis tuber, the root of Dahurain angelica 5-100
Gram.
3. according to a kind of pharmaceutical composition radix scrophulariae for treating the cancer of the brain of claim 1,2, Radix Codonopsis, Radix Angelicae Sinensis, the Radix Astragali, cultivated land, Chinese yam,
Matrimony vine, the bighead atractylodes rhizome, Poria cocos, Divine Comedy, rhizoma zingiberis, Ligusticum wallichii, Rhizoma Sparganii, curcuma zedoary, safflower, peach kernel, pseudo-ginseng, field pennycress, marine alga, the red sage root, Chinese herbaceous peony
Son, corydalis tuber, the root of Dahurain angelica are Market of Chinese Materia Medica through processing or wild and plantation Chinese medicine.
4. a kind of pharmaceutical composition for treating the cancer of the brain, mainly there is the preparation that following raw material is prepared into:Radix scrophulariae 50-800
Part, 10-100 parts of Ligusticum wallichii, 10-50 parts of Radix Codonopsis, 5-50 parts of Radix Angelicae Sinensis, 5-100 parts of the Radix Astragali, 10-100 parts of cultivated land, Chinese yam 10-
150 parts, 5-100 parts of matrimony vine, 10-100 parts of the bighead atractylodes rhizome, 5-50 parts of Poria cocos, 5-50 parts of Divine Comedy, 5-50 parts of rhizoma zingiberis, plantain seed
5-100 parts, 10-50 parts of Rhizoma Sparganii, 10-50 parts of curcuma zedoary, 10-50 parts of safflower, 10-50 parts of peach kernel, 10-50 parts of pseudo-ginseng, lose
10-100 parts of sauce grass, 10-100 parts of marine alga, 10-50 parts of the red sage root, 10-50 parts of corydalis tuber, 10-50 parts of the root of Dahurain angelica.
5. a kind of pharmaceutical composition for treating the cancer of the brain according to claim 4, the most preferably following parts by weight group of the raw material components
Point:300 parts of radix scrophulariae, 50 parts of Ligusticum wallichii, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 60 parts of the Radix Astragali, 60 parts of cultivated land, 60 parts of Chinese yam, 20 parts of matrimony vine,
60 parts of the bighead atractylodes rhizome, 20 parts of Poria cocos, 20 parts of rhizoma zingiberis, 30 parts of plantain seed, 20 parts of Rhizoma Sparganii, 20 parts of curcuma zedoary, 20 parts of safflower, 20 parts of peach kernel, three
7 20 parts, 50 parts of field pennycress, 20 parts of marine alga, 20 parts of the red sage root, 10 parts of Divine Comedy, 20 parts of corydalis tuber, 20 parts of the root of Dahurain angelica.
6. according to claim 4,5 it is a kind of treat the pharmaceutical composition of the cancer of the brain described in raw material components can be it is dialectical treat, by
Radix scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Radix Astragali, cultivated land, Chinese yam, matrimony vine, the bighead atractylodes rhizome, Poria cocos, Divine Comedy, rhizoma zingiberis, Ligusticum wallichii, Rhizoma Sparganii, curcuma zedoary, safflower, peach
Benevolence, pseudo-ginseng, field pennycress, marine alga, the red sage root, plantain seed, corydalis tuber, the root of Dahurain angelica and other blood circulation promoting and enrichings, tonifying middle-Jiao and Qi, kidney and spleen invigorating
Stomach, the reinforcing life power such as softening hardness and resolving stasis strengthens the viable organism energy, the prescription Chinese herbal medicine group of adjustment life organic whole balance
Into.
7. according to a kind of preparation method of pharmaceutical composition for treating the cancer of the brain of claim 1,2,3,4,5,6, including following step
Suddenly:Get it filled compositions decocting, then prepared by medicament common method.
8. according to a kind of pharmaceutical composition for treating the cancer of the brain of claim 1,2,3,4,5,6,7, the medicine refers to any one
Plant oral administered dosage form described in pharmacy:Oral liquid, granule, capsule, tablet, effervescent tablet etc..
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710416246.0A CN107184936A (en) | 2017-06-06 | 2017-06-06 | Treat pharmaceutical composition of the cancer of the brain and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710416246.0A CN107184936A (en) | 2017-06-06 | 2017-06-06 | Treat pharmaceutical composition of the cancer of the brain and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107184936A true CN107184936A (en) | 2017-09-22 |
Family
ID=59877761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710416246.0A Pending CN107184936A (en) | 2017-06-06 | 2017-06-06 | Treat pharmaceutical composition of the cancer of the brain and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107184936A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107137517A (en) * | 2017-07-03 | 2017-09-08 | 曹国荣 | Eliminate autonomic drug and pharmaceutical composition of Pain Treatment cancer and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101745063A (en) * | 2008-12-15 | 2010-06-23 | 张峻峰 | Chinese patent medicine for resisting cancer |
-
2017
- 2017-06-06 CN CN201710416246.0A patent/CN107184936A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101745063A (en) * | 2008-12-15 | 2010-06-23 | 张峻峰 | Chinese patent medicine for resisting cancer |
Non-Patent Citations (2)
| Title |
|---|
| 李旭庄: "李旭蕃运用补阳还五汤治疗脑瘤3例", 《江苏中医药》 * |
| 贺国柱等: "通软散调法治疗脑瘤1例", 《陕西中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107137517A (en) * | 2017-07-03 | 2017-09-08 | 曹国荣 | Eliminate autonomic drug and pharmaceutical composition of Pain Treatment cancer and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104288644A (en) | A kind of pharmaceutical composition for treating spleen deficiency and its preparation method | |
| CN101926882A (en) | Medicinal composition for treating cancer and preparation methods thereof | |
| CN107137517A (en) | Eliminate autonomic drug and pharmaceutical composition of Pain Treatment cancer and preparation method thereof | |
| CN107296935A (en) | A kind of Chinese medicine composition and Chinese medicine preparation for treating peripheral facial paralysis | |
| CN107184936A (en) | Treat pharmaceutical composition of the cancer of the brain and preparation method thereof | |
| CN108057107A (en) | A kind of pharmaceutical composition of rapid drop and elimination malignant tumour and preparation method thereof | |
| CN103798472B (en) | A kind of health protection tea and health care's preparation | |
| CN104306558B (en) | Constipation moistening dryness for relaxing bowels preparation and preparation method caused by stomach fire is contained | |
| CN102366579B (en) | Preparation method of traditional Chinese medicine lotion for treating clothes lack-type bedsore | |
| CN107184869A (en) | A kind of pharmaceutical composition for treating gout anti-trioxypurine and preparation method thereof | |
| CN104888132A (en) | Traditional Chinese medicine composition for treatment of chronic gastritis | |
| CN104998074A (en) | Traditional Chinese medicine for treating gastropathy and preparation method thereof | |
| CN105343688A (en) | A kind of pharmaceutical composition for treating myocardial infarction and its application | |
| CN104721753A (en) | Medicine for treating liver-wind stirring type brain tumor and preparation method of medicine | |
| CN104758528A (en) | Traditional Chinese medicine composition for treating headache | |
| CN107823343A (en) | A kind of pharmaceutical composition for treating rheumathritis and medicinal liquor and preparation method thereof | |
| CN108853292A (en) | A kind of Chinese medicine and preparation method thereof for treating allergic rhinitis | |
| CN101537090A (en) | Pharmaceutical composition for treating lumbar intervertebral disc protrusion, preparation method and use thereof | |
| CN103191336B (en) | Method for preparing drug for treating esophageal achalasia | |
| CN105920139A (en) | Traditional Chinese medicine tea capable of resisting and preventing cancers | |
| CN107789583A (en) | A kind of pharmaceutical composition for eliminating metastatic carcinoma of bone cell and preparation method thereof | |
| CN107362232A (en) | Treat autonomic drug and pharmaceutical composition of leukemia and preparation method thereof | |
| CN105521335A (en) | Traditional Chinese medicine for treating paroxysmal supraventricular tachycardia and preparation method of traditional Chinese medicine | |
| CN105616559A (en) | Composition for treating acute bacillary dysentery | |
| CN104758675A (en) | Traditional Chinese medicine composition for treating migraine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170922 |
|
| RJ01 | Rejection of invention patent application after publication |