CN101528309A - 包括给予维生素d化合物和另外的治疗剂的治疗癌症的方法 - Google Patents
包括给予维生素d化合物和另外的治疗剂的治疗癌症的方法 Download PDFInfo
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- CN101528309A CN101528309A CNA2007800385939A CN200780038593A CN101528309A CN 101528309 A CN101528309 A CN 101528309A CN A2007800385939 A CNA2007800385939 A CN A2007800385939A CN 200780038593 A CN200780038593 A CN 200780038593A CN 101528309 A CN101528309 A CN 101528309A
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- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US93492406P | 2006-08-25 | 2006-08-25 | |
| US60/934,924 | 2006-08-25 |
Publications (1)
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| CN101528309A true CN101528309A (zh) | 2009-09-09 |
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Family Applications (1)
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| EP (2) | EP2425874A3 (enExample) |
| JP (1) | JP2010501576A (enExample) |
| KR (1) | KR20090060306A (enExample) |
| CN (1) | CN101528309A (enExample) |
| AU (1) | AU2007287099A1 (enExample) |
| CA (2) | CA2661546A1 (enExample) |
| IL (1) | IL197212A0 (enExample) |
| NO (1) | NO20091191L (enExample) |
| WO (1) | WO2008024485A2 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110123812A (zh) * | 2013-01-15 | 2019-08-16 | 阿拉贡药品公司 | 雄激素受体调节剂及其用途 |
| US11491149B2 (en) | 2017-10-16 | 2022-11-08 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
| USRE49353E1 (en) | 2012-09-26 | 2023-01-03 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2981549A1 (en) * | 2009-01-27 | 2010-08-05 | Berg Llc | Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy |
| UA105794C2 (uk) | 2009-06-26 | 2014-06-25 | Новартіс Аг | 1,3-ДИЗАМІЩЕНІ ПОХІДНІ ІМІДАЗОЛІДИН-2-ОНУ ЯК ІНГІБІТОРИ Cyp17 |
| WO2011007208A1 (en) * | 2009-07-16 | 2011-01-20 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Compounds and methods for the treatment of cancer |
| JP2013537210A (ja) | 2010-09-16 | 2013-09-30 | ノバルティス アーゲー | １７α−ヒドロキシラーゼ／Ｃ１７，２０−リアーゼ阻害剤 |
| US20120116381A1 (en) | 2010-11-05 | 2012-05-10 | Houser Kevin L | Surgical instrument with charging station and wireless communication |
| EA023064B1 (ru) | 2011-04-28 | 2016-04-29 | Новартис Аг | ИНГИБИТОРЫ 17α-ГИДРОКСИЛАЗЫ/C-ЛИАЗЫ |
| US9801844B2 (en) * | 2012-05-24 | 2017-10-31 | The Research Foundation Of The City University Of New York | Methods and compositions for the treatment of cancer |
| WO2014058785A1 (en) | 2012-10-10 | 2014-04-17 | Novartis Ag | Combination therapy |
| EP2988752A4 (en) | 2013-04-24 | 2017-01-18 | Salk Institute for Biological Studies | Vitamin d receptor/smad genomic circuit gates fibrotic response |
| CN105451818A (zh) | 2013-06-05 | 2016-03-30 | 萨克生物研究学院 | 治疗涉及cxcl12活性的疾病的维生素d受体激动剂 |
| WO2019023149A1 (en) | 2017-07-24 | 2019-01-31 | Salk Institute For Biological Studies | USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5120722A (en) | 1984-02-08 | 1992-06-09 | Hoffmann-La Roche Inc. | Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia |
| US4857518A (en) | 1984-10-04 | 1989-08-15 | Wisconsin Alumni Research Foundation | Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same |
| US4717721A (en) | 1985-05-30 | 1988-01-05 | Howard W. Bremer | Sidechain homo-vitamin D compounds with preferential anti-cancer activity |
| WO1987000834A1 (en) | 1985-08-02 | 1987-02-12 | Leo Pharmaceutical Products Ltd. A/S | Novel vitamin d analogues |
| US5145846A (en) | 1988-01-20 | 1992-09-08 | Hoffmann-La Roche Inc. | Vitamin D3 analogs |
| US4851401A (en) | 1988-07-14 | 1989-07-25 | Wisconsin Alumni Research Foundation | Novel cyclopentano-vitamin D analogs |
| CA1333616C (en) | 1989-03-09 | 1994-12-20 | Hector F. Deluca | 19-nor-vitamin d compounds |
| GB8915770D0 (en) | 1989-07-10 | 1989-08-31 | Leo Pharm Prod Ltd | Chemical compounds |
| DE4101953A1 (de) | 1991-01-19 | 1992-07-23 | Schering Ag | 23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel |
| DE4141746A1 (de) | 1991-12-13 | 1993-06-17 | Schering Ag | 20-methyl-substituierte vitamin d-derivate |
| DE69327096T2 (de) * | 1992-03-31 | 2000-06-21 | Btg International Ltd., London | 17-substituierte steroide, verwendbar bei behandlung von krebs |
| US5604213A (en) | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
| US5547947A (en) | 1993-03-11 | 1996-08-20 | Hoffmann-La Roche Inc. | Methods of treatment |
| GB9622590D0 (en) | 1996-10-30 | 1997-01-08 | Leo Pharm Prod Ltd | Chemical compounds |
| EP2340840B1 (en) | 1998-03-27 | 2012-08-29 | Oregon Health Sciences University | Pulse dose Vitamin D drug for the treatment of hyperproliferative skin diseases |
| ES2300323T3 (es) * | 2000-03-02 | 2008-06-16 | Univ Pittsburgh | Quimioterapia combinada. |
| US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
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2007
- 2007-08-23 CA CA002661546A patent/CA2661546A1/en not_active Abandoned
- 2007-08-23 KR KR1020097005973A patent/KR20090060306A/ko not_active Withdrawn
- 2007-08-23 AU AU2007287099A patent/AU2007287099A1/en not_active Abandoned
- 2007-08-23 EP EP11175046.9A patent/EP2425874A3/en not_active Withdrawn
- 2007-08-23 CN CNA2007800385939A patent/CN101528309A/zh active Pending
- 2007-08-23 EP EP07837327A patent/EP2063963A2/en not_active Withdrawn
- 2007-08-23 CA CA2838089A patent/CA2838089A1/en not_active Abandoned
- 2007-08-23 JP JP2009525648A patent/JP2010501576A/ja active Pending
- 2007-08-23 WO PCT/US2007/018770 patent/WO2008024485A2/en not_active Ceased
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- 2009-02-24 IL IL197212A patent/IL197212A0/en unknown
- 2009-03-20 NO NO20091191A patent/NO20091191L/no not_active Application Discontinuation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE49353E1 (en) | 2012-09-26 | 2023-01-03 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| USRE50642E1 (en) | 2012-09-26 | 2025-10-21 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| CN110123812A (zh) * | 2013-01-15 | 2019-08-16 | 阿拉贡药品公司 | 雄激素受体调节剂及其用途 |
| US11491149B2 (en) | 2017-10-16 | 2022-11-08 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008024485A2 (en) | 2008-02-28 |
| EP2425874A3 (en) | 2013-05-15 |
| CA2838089A1 (en) | 2008-02-28 |
| JP2010501576A (ja) | 2010-01-21 |
| WO2008024485A3 (en) | 2009-03-05 |
| IL197212A0 (en) | 2009-12-24 |
| NO20091191L (no) | 2009-03-23 |
| KR20090060306A (ko) | 2009-06-11 |
| EP2425874A2 (en) | 2012-03-07 |
| CA2661546A1 (en) | 2008-02-28 |
| EP2063963A2 (en) | 2009-06-03 |
| AU2007287099A1 (en) | 2008-02-28 |
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Application publication date: 20090909 |