CN101524463A - Chinese medicinal composition for treating pulmonitis and preparation method thereof - Google Patents
Chinese medicinal composition for treating pulmonitis and preparation method thereof Download PDFInfo
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- CN101524463A CN101524463A CN200810101488A CN200810101488A CN101524463A CN 101524463 A CN101524463 A CN 101524463A CN 200810101488 A CN200810101488 A CN 200810101488A CN 200810101488 A CN200810101488 A CN 200810101488A CN 101524463 A CN101524463 A CN 101524463A
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Abstract
The invention relates to a Chinese medicinal composition for treating pulmonitis, which is prepared from radix bupleuri, white mustard seed, honeysuckle flower, pinellia tuber, rhizoma atractylodis macrocephalae, raw rhubarb, tangerine peel, almond, indigowoad root, unibract fritillary bulb, dandelion, farsythio, raw licorice root, poria, heartleaf houttuynia herb, burdock, earthworm, bombyx batryticatus, bulbus fritillariae thunbergii, and/or a pharmaceutically acceptable carrier. The invention also relates to a preparation method for the Chinese medicinal composition. The Chinese medicinal composition has the efficacies of ventilating and clearing the lung, relieving cough and asthma, and clearing heat and transforming phlegm, and is used for treating symptoms of fever, cough, profuse sputum, chest pain, and the like which are caused by the pulmonitis resulting from phlegm-heat syndrome and lung loss of clearing and depurating.
Description
Technical field:
The present invention relates to a kind of Chinese medicine composition, specifically, relate to a kind of Chinese medicine composition for the treatment of pneumonia and preparation method thereof.
Background technology
Lung is " tender dirty ", communicates with atmosphere, and the systemic blood lungs of flowing through, the invasion and attack that subject to pathogenic microorganism cause pneumonia, are commonly referred to pneumonia.Invade the inflammation that lungs cause because pneumonia is pathogenic microorganism such as antibacterial, virus, therefore, pneumonia of a great variety can be divided into lobar pneumonia, bronchiolitis and interstitial pneumonia by the region of anatomy.Can be divided into bacillary, viral, mycoplasma, rickettsia and fungoid etc. by pathogenic microorganism.
The pathogen that causes pneumonia comprises various biological virulence factors from virus to the parasite, and is wherein common with antibacterial, secondly is virus.General between twenty and fifty bacillary lobar pneumonia, easy ill toxicity lobule of old germling weak person or the interstitial pneumonias suffered from more.
Also each is variant for the pneumonia that pathogen is different, its disease symptom:
1. bacterial pneumonia: before the morbidity upper respiratory tract infection symptoms is often arranged, onset is hurried, and hyperpyrexia is arranged usually, and body temperature can rise to 39 ground Celsius～40 degrees centigrade in a few hours.Stabbing pain over the chest is with breathing and the cough aggravation.Cough rust or a small amount of purulent sputum during cough.Often with feeling sick, vomitting, the whole body does not accommodate muscular soreness.Its sings and symptoms can be because of the difference of bacteria infection difference to some extent.
2. viral pneumonia: onset is slow, headache, weak, muscular soreness, heating, cough, dry cough or sticking on a small quantity expectorant.The influenza virus pneumonia begins to be typical flu-like symptom, in 12～36 hours, and tachypnea, respiratory failure and shock can take place, two lung audibles and moist rale or wheezing sound in carrying out property dyspnea, cyanosis.
3. mycoplasma pneumonia: initial symptom is similar to influenza, has the whole body uncomfortable, has sore throat and dry cough, and along with progression of disease, the paroxysmal cough can appear in sx, and mucus purulence or bloodshot sputum are arranged during cough.The primary disease slower development.Acute symptom generally continued for 1～2 week, recovered gradually immediately.But cause adult respiratory distress syndrome when a few patients is serious.
4. fungal pneumonia: the similar acute pneumonia of symptom, the heating fear of cold is coughed white sputum crudum, and the yeast stink is arranged, and also can be gelatin, occurs symptoms such as spitting of blood, tachypnea sometimes.
Pneumonia all can take place throughout the year, sees but big in temperature Change, rapid cold rapid warm winter-spring season especially more.The generation of pneumonia is untimely because of flu (upper respiratory tract infection) treatment mostly, infect and down to spread due to the pulmonary, minority can by haematogenous infect or the organ infection of adjacent tissue due to.So the prevention pneumonia can be started with from the following aspects:
1, reaches the early treatment flu
Flu is the infection of above (comprising pharynx, larynx, palatine tonsil and nose) of larynx cricoid cartilage.Great majority are viral infection.As treat in time properly, then great majority can be fully recovered in several days.As treat untimelyly or improper, and then infect and spread downwards to lung, cause pneumonia.
2, infect in anti-hemostasis source
Minority pneumonia patient is arranged, and its reason that causes pneumonia is not a flu, but the infection beyond the lung, as skin soft-tissue infection, septicemia etc.Its pathogeny is that the pathogen (almost being antibacterial entirely) of local infection or systemic infection arrives lung by blood circulation, causes pulmonary infection, so claim the haematogenous pneumonia.
3, prevent contiguous the infection
The contiguous infection near the histoorgan (as visceral pericardium, pleura, liver, gallbladder, spleen etc.) the pulmonary infects, its pathogen direct extension be to lung, causes that lung tissue is inflamed, due to the hyperemia, edema etc.
4, inoculation pneumovax
Healthy people for no above-mentioned pneumonia inducement can not sleep without any anxiety.Lungs communicate with the external world by respiratory tract, all might be invaded by pathogen at any time, are inflamed.For this reason, the preferably annual inoculation pneumovax of healthy people (especially infant and old people) is with enhancing immunity.Though this method can not avoid taking place pneumonia fully, in case morbidity, but mitigation symptoms shortens the course of disease, and the generation that reduces complication (as respiratory failure, heart failure and pulmonary encephalopathy etc.).
The traditional Chinese medical science thinks that pneumonia belongs to pathogenic wind-warm, cough, the syndrome of dyspnea category.Lung has intrinsic heat, and table Wei Bugu is subjected to pathogenic warmth outward, attacking the lung first, and expectorant heat is handed over resistance, impairment of purifying function of the lung.The etiology and pathology of pneumonia is, the exopathogenic factor duty in the ailment said due to cold or exposure diseases caused by exogenous pathogenic factor, endogenous cause of ill duty tender and lovely in lungs, the resistance against diseases deficiency, spleen is often involved mainly at lung in sick position, also can influence conscience.Expectorant heat is main pathological product, and the lung qi obturation is the final result that pathology develops, and is heavy then can cause blood stasis.Lung closes with blood stasis can form the pathology circulation, reciprocal causation, and it is weak to be critically ill, deficient vital QI leading to lingering of pathogen, often causing a disease, feelings are touching not to heal.
The primary disease initial stage is similar with flu, but the exterior syndrome time is of short duration, and in very fast heat-transformation was gone into, main feature was heating, cough and asthma, and flaring of nares, tears all do not have, and this is the common characteristic of primary disease.Sick just for experiencing ailment said due to cold or exposure, distinguish wind and cold or wind heat.Cold reheating gently, it is bad-looking then to cough sound, and expectorant is rare clearly in vain, and tongue is not red, and tongue is thick in vain, floating and tense pulse; Thermogravimetric is cold light, and it is sticking or yellow then to cough fullness of tone expectorant, tongue tip side of red, and tongue approaches white or BOHUANG, floating and rapid pulse more.The heap soil or fertilizer over and around the roots of expectorant heat is contained when lung, and differentiate the expectorant escheat is thermogravimetric.Expectorant weight person coughs acutely, the tachypnea flaring of nares, and gurgling with sputum, even expectorant sound is filtered chest expansion with rough respiration etc., red tongue thick and greasy fur or yellow greasy, slippery and rapid pulse; Thermogravimetric person's hyperpyrexia is delaied and is not moved back, flushed face and red lips, and the excessive thirst taking fluids profusely, restlessness, dry cough without phlegm, constipation, red tongue plays thorn, and yellow fur is rough, full and large pulse.Distinguish light disease, serious symptom, change disease.Common pneumonia is based on cough, flaring of nares, heating, doublely sees the tears impatency, as dyspnea occurs, and face is livid purple, is the time of serious symptom; If the meeting color is pale, extremity are not warm, obnubilation, and lethargy or breathing are whole, and bleeding tendency etc. is arranged, and all are that danger is waited.
The western medical treatment common antibiotics, as penicillin, cephalosporin etc., many easily generation allergic symptoms, and side effect is big.Transfer outer mode of supporting in the traditional Chinese medical science then adopts, make its treating both the principal and secondary aspects of a disease.The traditional Chinese medical science adopts that lung qi dispersing is respectful to fall antiasthmatic-antitussive, this disease of the decoction for the treatment of removing heat-phlegm.From the beginning of closing lung, control to declare and loose for earlier for ailment said due to cold or exposure; Then phlegm-heat obstructing in the lung, the lung qi impatency is controlled with clearing away phlegm and is opened lung, and the heat clearing away Dingchuan is a method.Disease is the then cloudy consume of gas for a long time, based on boosting qi and nourishing yin.Various deteriorated cases as the gas deficiency of YIN person of declining, are answered supplementing QI to prevent collapse, recuperating depleted YANG and rescuing the patient from collapse; Evil sunken conscience person should be with removing heat from the heart to restore the consciousness, measures such as suppressing the hyperactive liver to relieve the wind syndrome.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of pneumonia.
The present invention also aims to provide a kind of preparation method of this Chinese medicine composition.
In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of pneumonia, be to make by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is made by weight by following raw materials according:
Radix Bupleuri 10-30 part Semen Sinapis Albae 5-15 part Flos Lonicerae 20-40 part
Rhizoma Pinelliae 5-10 part Bulbus Fritillariae Thunbergii 10-30 part Rhizoma Atractylodis Macrocephalae 10-20 part
Radix Et Rhizoma Rhei 5-20 part Pericarpium Citri Reticulatae 20-40 part Semen Armeniacae Amarum 15-30 part
Radix Isatidis 5-15 part Bulbus Fritillariae Cirrhosae 4-10 part Herba Taraxaci 20-30 part
Fructus Forsythiae 15-25 part Radix Glycyrrhizae 10-20 part Poria 5-20 part
The other sub-5-20 part Pheretima 20-40 part of Herba Houttuyniae 25-35 part cattle
Bombyx Batryticatus 15-30 part
Effective ingredient is preferably made by weight by following raw materials according:
33 parts of 12 portions of Flos Loniceraes of 23 parts of Semen Sinapis Albaes of Radix Bupleuri
16 parts of 23 parts of Rhizoma Atractylodis Macrocephalaes of 8 parts of Bulbus Fritillariae Thunbergii of the Rhizoma Pinelliae
24 parts in 33 parts of Semen Armeniacae Amarums of 14 parts of Pericarpium Citri Reticulataes of Radix Et Rhizoma Rhei
26 parts of 8 parts of Herba Taraxacis of 12 parts of Bulbus Fritillariae Cirrhosaes of Radix Isatidis
14 parts of 16 parts of Poria of 22 parts of Radix Glycyrrhizae of Fructus Forsythiae
33 parts of 14 parts of Pheretimas of the other son of 32 portions of cattle of Herba Houttuyniae
24 parts of Bombyx Batryticatus
The present invention also provides a kind of preparation method of this Chinese medicine composition, comprises the steps:
(1) Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Isatidis, Radix Glycyrrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Semen Sinapis Albae, Flos Lonicerae, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Herba Taraxaci, Fructus Forsythiae, Poria, Herba Houttuyniae, the other son of cattle, Pheretima, Bombyx Batryticatus, Bulbus Fritillariae Thunbergii decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds clear paste and dextrin, drying, be ground into fine powder, make granule, capsule, tablet and pill with pharmaceutically acceptable carrier.
Pharmaceutical composition of the present invention can with receivable carrier pharmaceutically, for example: filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Mode by granule, capsule, tablet and pill oral administration is used.
Chinese medicine composition of the present invention has that lung qi dispersing is respectful to fall, antiasthmatic-antitussive, and the effect of removing heat-phlegm is used for expectorant heat and hands over diseases such as pneumonia causes due to resistance, the impairment of purifying function of the lung fever, cough, excessive phlegm, chest pain.
The specific embodiment:
Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.
Embodiment 1 Chinese medicinal composition granules of the present invention
(1) Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Isatidis, Radix Glycyrrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Semen Sinapis Albae, Flos Lonicerae, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Herba Taraxaci, Fructus Forsythiae, Poria, Herba Houttuyniae, the other son of cattle, Pheretima, Bombyx Batryticatus, Bulbus Fritillariae Thunbergii decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned clear paste and dextrin 800g, drying is ground into fine powder, adds dextrin 200g, lactose 400g, mixing, with 80% ethanol wet granulation promptly.
Embodiment 2 Chinese medicinal composition capsules agent of the present invention
(1) Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Isatidis, Radix Glycyrrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Semen Sinapis Albae, Flos Lonicerae, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Herba Taraxaci, Fructus Forsythiae, Poria, Herba Houttuyniae, the other son of cattle, Pheretima, Bombyx Batryticatus, Bulbus Fritillariae Thunbergii decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned clear paste and dextrin 400g, drying is ground into fine powder, dry, be ground into fine powder, mixing, in the capsulae vacuus of packing into promptly.
Embodiment 3 Chinese medicine composition tablets of the present invention
(1) Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Isatidis, Radix Glycyrrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Semen Sinapis Albae, Flos Lonicerae, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Herba Taraxaci, Fructus Forsythiae, Poria, Herba Houttuyniae, the other son of cattle, Pheretima, Bombyx Batryticatus, Bulbus Fritillariae Thunbergii decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned clear paste and dextrin 400g, drying is ground into fine powder, dry, be ground into fine powder, add starch 300g, carboxymethylstach sodium 100g, mixing, with 70% ethanol wet granulation, tabletting, coating are promptly.
Embodiment 4 Chinese medicine composition pills of the present invention
(1) Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Isatidis, Radix Glycyrrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Semen Sinapis Albae, Flos Lonicerae, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Herba Taraxaci, Fructus Forsythiae, Poria, Herba Houttuyniae, the other son of cattle, Pheretima, Bombyx Batryticatus, Bulbus Fritillariae Thunbergii decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned clear paste and dextrin 800 1, dry, be ground into fine powder, sieve, mixing, every 100g medicated powder adds refined honey 40g and suitable quantity of water, general ball, drying is made small honey pill.
Claims (4)
1, a kind of Chinese medicine composition for the treatment of pneumonia is to be made by effective ingredient and/or pharmaceutically acceptable carrier, it is characterized in that described effective ingredient is made by weight by following raw materials according:
Radix Bupleuri 10-30 part Semen Sinapis Albae 5-15 part Flos Lonicerae 20-40 part
Rhizoma Pinelliae 5-10 part Bulbus Fritillariae Thunbergii 10-30 part Rhizoma Atractylodis Macrocephalae 10-20 part
Radix Et Rhizoma Rhei 5-20 part Pericarpium Citri Reticulatae 20-40 part Semen Armeniacae Amarum 15-30 part
Radix Isatidis 5-15 part Bulbus Fritillariae Cirrhosae 4-10 part Herba Taraxaci 20-30 part
Fructus Forsythiae 15-25 part Radix Glycyrrhizae 10-20 part Poria 5-20 part
The other sub-5-20 part Pheretima 20-40 part of Herba Houttuyniae 25-35 part cattle
Bombyx Batryticatus 15-30 part
2, Chinese medicine composition as claimed in claim 1 is characterized in that described effective ingredient made by weight by following raw materials according:
33 parts of 12 portions of Flos Loniceraes of 23 parts of Semen Sinapis Albaes of Radix Bupleuri
16 parts of 23 parts of Rhizoma Atractylodis Macrocephalaes of 8 parts of Bulbus Fritillariae Thunbergii of the Rhizoma Pinelliae
24 parts in 33 parts of Semen Armeniacae Amarums of 14 parts of Pericarpium Citri Reticulataes of Radix Et Rhizoma Rhei
26 parts of 8 parts of Herba Taraxacis of 12 parts of Bulbus Fritillariae Cirrhosaes of Radix Isatidis
14 parts of 16 parts of Poria of 22 parts of Radix Glycyrrhizae of Fructus Forsythiae
33 parts of 14 parts of Pheretimas of the other son of 32 portions of cattle of Herba Houttuyniae
24 parts of Bombyx Batryticatus
3,, it is characterized in that described Chinese medicine composition can be made into granule, capsule, tablet, pill as the arbitrary described Chinese medicine composition of claim 1-2.
4, a kind of preparation method as the arbitrary described Chinese medicine composition of claim 1-3 comprises the steps:
(1) Radix Bupleuri, Radix Et Rhizoma Rhei, Radix Isatidis, Radix Glycyrrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(2) Semen Sinapis Albae, Flos Lonicerae, the Rhizoma Pinelliae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Bulbus Fritillariae Cirrhosae, Herba Taraxaci, Fructus Forsythiae, Poria, Herba Houttuyniae, the other son of cattle, Pheretima, Bombyx Batryticatus, Bulbus Fritillariae Thunbergii decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned clear paste and dextrin, drying, be ground into fine powder, make granule, capsule, tablet, pill with pharmaceutically acceptable carrier.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810101488A CN101524463A (en) | 2008-03-07 | 2008-03-07 | Chinese medicinal composition for treating pulmonitis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810101488A CN101524463A (en) | 2008-03-07 | 2008-03-07 | Chinese medicinal composition for treating pulmonitis and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611024A (en) * | 2013-12-06 | 2014-03-05 | 杨云 | Traditional Chinese medicine for treating pneumonia |
| CN103656537A (en) * | 2013-12-30 | 2014-03-26 | 魏本松 | Traditional Chinese medicine for treating pneumonia |
| CN104013861A (en) * | 2014-06-30 | 2014-09-03 | 吴翠霞 | Traditional Chinese medicine composition for treating infantile pneumonia |
| CN104352955A (en) * | 2014-10-17 | 2015-02-18 | 王洪强 | Traditional Chinese medicine for treating pneumonia |
| CN104721507A (en) * | 2015-02-27 | 2015-06-24 | 李晓枫 | Traditional Chinese medicine composition for treating pneumonia |
| CN107115454A (en) * | 2017-05-31 | 2017-09-01 | 成都风靡生物科技有限公司 | It is a kind of effectively to treat Chinese medicine composition of pneumonia and preparation method thereof |
| CN108478655A (en) * | 2018-05-17 | 2018-09-04 | 福建省安溪县苷芝宝食品科技有限公司 | The moisture cream for the treatment of pneumonia prolongs slurry and its preparation process |
-
2008
- 2008-03-07 CN CN200810101488A patent/CN101524463A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611024A (en) * | 2013-12-06 | 2014-03-05 | 杨云 | Traditional Chinese medicine for treating pneumonia |
| CN103656537A (en) * | 2013-12-30 | 2014-03-26 | 魏本松 | Traditional Chinese medicine for treating pneumonia |
| CN103656537B (en) * | 2013-12-30 | 2015-09-02 | 魏本松 | A kind of Chinese medicine for the treatment of pneumonia |
| CN104013861A (en) * | 2014-06-30 | 2014-09-03 | 吴翠霞 | Traditional Chinese medicine composition for treating infantile pneumonia |
| CN104352955A (en) * | 2014-10-17 | 2015-02-18 | 王洪强 | Traditional Chinese medicine for treating pneumonia |
| CN104721507A (en) * | 2015-02-27 | 2015-06-24 | 李晓枫 | Traditional Chinese medicine composition for treating pneumonia |
| CN107115454A (en) * | 2017-05-31 | 2017-09-01 | 成都风靡生物科技有限公司 | It is a kind of effectively to treat Chinese medicine composition of pneumonia and preparation method thereof |
| CN108478655A (en) * | 2018-05-17 | 2018-09-04 | 福建省安溪县苷芝宝食品科技有限公司 | The moisture cream for the treatment of pneumonia prolongs slurry and its preparation process |
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Open date: 20090909 |