CN101518603A - Traditional Chinese medical composition used for treating prostatic hyperplasia and preparation method thereof - Google Patents
Traditional Chinese medical composition used for treating prostatic hyperplasia and preparation method thereof Download PDFInfo
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- CN101518603A CN101518603A CN200810101176A CN200810101176A CN101518603A CN 101518603 A CN101518603 A CN 101518603A CN 200810101176 A CN200810101176 A CN 200810101176A CN 200810101176 A CN200810101176 A CN 200810101176A CN 101518603 A CN101518603 A CN 101518603A
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Abstract
The invention discloses a traditional Chinese medical composition used for treating prostatic hyperplasia, which is made from medical components and/or a pharmaceutically acceptable carrier, wherein codonopsis pilosula, raidx astragali, Chinese eaglewood, Chinese angelica, Cowherb Seed, largehead atractylodes rhizome, tangerine peel, grifola, indian buead, rehmannia glutinosa, barbary wolfberry fruit, grass leaf sweelflag Rhizome, earthworm and the like are extracted and prepared to obtain the medical components. The composition has the functions of relieving stranguria by diuresis, activating blood circulation to dissipate blood stasis, resolving masses and relieving pain, is applied to treating kidney and spleen deficiency, Qi stagnation and blood stasis, prostatic hyperplasia, chronic prostatitis, pale complexion, fatigue weakness, waist and knee weakness and inability, lower abdomen pain, difficulty in urinating, frequency of micturition, urgency of urination or urethral pain. The invention also discloses a method for preparing the traditional Chinese medicine.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of Chinese medicine composition for the treatment of prostatic hyperplasia and preparation method thereof.
Technical background
Prostatic hyperplasia once was called prostate hyperplasia, and pilosity is born in the old people more than 50 years old.According to states such as America and Europe statistics, its sickness rate is up to more than 80% in elderly men; Domestic report is lower, but also reaches more than 50%.Because prostate is positioned at the bladder outlet place just, round the specific position of urethra,, just can oppress urethra from all quarter in case hypertrophy takes place, intravesical urine is discharged be obstructed, cause a series of pathological changes of urinary system.
So-called hypertrophy is meant owing to parenchyma quantity increases the tissue that causes, the volume increase of organ, is the cell mitogen activity enhanced results that a variety of causes causes.People's prostate is no exception, and is back to preadolescence certainly birth, prostatic growth, poor growth; After the adolescence, the speed of growth is accelerated, grew to the peak to about 24 years old approximately, weighing apparatus is fixed for its volume between 30～45 years old, and later some people trends towards atrophy, the body of gland smaller volume, another part people then can trend towards hypertrophy, and the body of gland volume increases gradually, if obviously oppress prostatic urethra, can cause bladder outlet portion to block and dysuric related symptoms, i.e. hyperplasia of prostate occur.Because this kind hypertrophy belongs to benign lesion,, be once called as and be prostate hyperplasia so its full name is benign prostate hyperplasia (Benign Prostatic Hyperp lasia is called for short BPH).
Prostate hyperplasia is meant prostatic hyperplasia of prostate, usually causes the prostatic urethra increased pressure, and resistance increases, and causes obstruction of bladder.Reveal any symptoms is: frequent micturition, and urgent micturition, frequent urination at night, the difficulty of urinating, weak stream of urine silk or interruption, urine drips for a long time not to the utmost.This disease complication may be a hydronephrosis, also may be uremia, so answer hig diligence.
Pure Chinese medicinal preparation of the present invention, but all medicines share both the kidney warming activating QI, tonneau bladder; Again can clearing away heat-damp and promoting diuresis, logical infirmity pain relieving; But and blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, make that kidney qi must be answered, blood stasis can disappear; Giving consideration to both the incidental and fundamental, simultaneously using both cold and hot drugs, benefit are not stayed heresy, are attacked and just do not hindering, receiving altogether the kidney warming activating QI; Relieving stranguria by diuresis, blood circulation promoting and blood stasis dispelling, the effect of removing obstruction for relieving pain.
The present invention also can use the different dosage form that is made into of various processes.Order of the present invention ground is to enrich medicine variety, further satisfies and ensured people's medication demand.Efficacy component of the present invention has relieving stranguria by diuresis, blood circulation promoting and blood stasis dispelling, the effect of removing obstruction for relieving pain.It is two empty to be used for the kidney spleen, qi depression to blood stasis, prostatic hyperplasia, chronic prostatitis; Complexion rolling is white, spiritlessness and weakness, and the waist knee joint is sluggish, sagging distention in the smaller abdomen, it is not well to urinate, and drop does not go out, or frequent micturition, urgent micturition, Urethra astringent pain.
Summary of the invention:
One of purpose of the present invention provides a kind of Chinese medicine composition for the treatment of prostatic hyperplasia and preparation method thereof.
Another purpose of the present invention provides the preparation method of this Chinese medicine composition.Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
120-360 parts of 50-200 parts of Lignum Aquilariae Resinatum of 50-200 parts of Radixs Astragali of Radix Codonopsis
100-300 parts of 100-300 parts of Rhizoma Atractylodis Macrocephalaes of 50-200 parts of Semen Vaccariae of Radix Angelicae Sinensis
50-200 parts in 150-200 parts of Poria of 100-300 parts of Polyporus of Pericarpium Citri Reticulatae
50-200 parts of 50-200 parts of Rhizoma Acori Graminei of 50-200 parts of Fructus Lycii of Radix Rehmanniae Preparata
50-200 parts of Pheretimas
The active component that preferred following raw materials according is made, curative effect is better:
160 parts of 80 portions of Lignum Aquilariae Resinatum of 80 parts of Radixs Astragali of Radix Codonopsis
150 parts of 150 parts of Rhizoma Atractylodis Macrocephalaes of 80 parts of Semen Vaccariae of Radix Angelicae Sinensis
100 parts in 150 parts of Poria of 150 portions of Polyporus of Pericarpium Citri Reticulatae
100 parts of 100 parts of Rhizoma Acori Graminei of 100 parts of Fructus Lycii of Radix Rehmanniae Preparata
50 parts of Pheretimas
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.Preparation technology:
(1) Radix Codonopsis, the Radix Astragali, that Radix Angelicae Sinensis powder is broken into fine powder is standby;
(2) Lignum Aquilariae Resinatum, Semen Vaccariae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Polyporus, Poria, Radix Rehmanniae Preparata, Fructus Lycii, Rhizoma Acori Graminei, Pheretima are added 8 times of water gagings and decoct 2 times, 2 hours for the first time, each 1 hour later on, filter, merging filtrate is condensed into clear paste; Add ethanol and make and contain alcohol amount and reach 75% (V/V) in clear paste, cold preservation 24 hours filters the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature 60 be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) with step (2) gained clear paste and step (1) gained fine powder mixing, drying is ground into dry powder, mixes with the conventional adjunct ingredient of medicine acceptable, can obtain corresponding different concrete dosage form.
Effective ingredient of the present invention can be prepared into oral formulations such as granule, tablet, capsule with acceptable accessories.
The effective ingredient of drug regimen of the present invention has relieving stranguria by diuresis, blood circulation promoting and blood stasis dispelling, the effect of removing obstruction for relieving pain.It is two empty to be used for the kidney spleen, qi depression to blood stasis, prostatic hyperplasia, chronic prostatitis; Complexion rolling is white, spiritlessness and weakness, and the waist knee joint is sluggish, sagging distention in the smaller abdomen, it is not well to urinate, and drop does not go out, or frequent micturition, urgent micturition, Urethra astringent pain.
The specific embodiment
Embodiment 1: the preparation technology of granule
160 parts of 80 portions of Lignum Aquilariae Resinatum of 80 parts of Radixs Astragali of Radix Codonopsis
150 parts of 150 parts of Rhizoma Atractylodis Macrocephalaes of 80 parts of Semen Vaccariae of Radix Angelicae Sinensis
100 parts in 150 parts of Poria of 150 portions of Polyporus of Pericarpium Citri Reticulatae
100 parts of 100 parts of Rhizoma Acori Graminei of 100 parts of Fructus Lycii of Radix Rehmanniae Preparata
50 parts of Pheretimas
(1) get Radix Codonopsis, the Radix Astragali, that Radix Angelicae Sinensis powder is broken into fine powder is standby;
(2) Lignum Aquilariae Resinatum, Semen Vaccariae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Polyporus, Poria, Radix Rehmanniae Preparata, Fructus Lycii, Rhizoma Acori Graminei, Pheretima are added 8 times of water gagings and decoct 2 times, 2 hours for the first time, each 1 hour later on, filter, merging filtrate is condensed into clear paste; Add ethanol and make and contain alcohol amount and reach 75% (V/V) in clear paste, cold preservation 24 hours filters the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature 60 be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) with step (2) gained clear paste and step (1) gained fine powder mixing, drying is ground into dry powder, adds the conventional adjuvant of medicine acceptable, granule, promptly.
Embodiment 2: the preparation technology of tablet
160 parts of 80 portions of Lignum Aquilariae Resinatum of 80 parts of Radixs Astragali of Radix Codonopsis
150 parts of 150 parts of Rhizoma Atractylodis Macrocephalaes of 80 parts of Semen Vaccariae of Radix Angelicae Sinensis
100 parts in 150 parts of Poria of 150 portions of Polyporus of Pericarpium Citri Reticulatae
100 parts of 100 parts of Rhizoma Acori Graminei of 100 parts of Fructus Lycii of Radix Rehmanniae Preparata
50 parts of Pheretimas
(1) Radix Codonopsis, the Radix Astragali, that Radix Angelicae Sinensis powder is broken into fine powder is standby;
(2) Lignum Aquilariae Resinatum, Semen Vaccariae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Polyporus, Poria, Radix Rehmanniae Preparata, Fructus Lycii, Rhizoma Acori Graminei, Pheretima are added 8 times of water gagings and decoct 2 times, 2 hours for the first time, each 1 hour later on, filter, merging filtrate is condensed into clear paste; Add ethanol and make and contain alcohol amount and reach 75% (V/V) in clear paste, cold preservation 24 hours filters the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature 60 be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) with step (2) gained clear paste and step (1) gained fine powder mixing, drying is ground into dry powder, adds right amount of auxiliary materials after making dry powder, and mixing is granulated, compacting in flakes, promptly.
Embodiment 3: the preparation technology of capsule
160 parts of 80 portions of Lignum Aquilariae Resinatum of 80 parts of Radixs Astragali of Radix Codonopsis
150 parts of 150 parts of Rhizoma Atractylodis Macrocephalaes of 80 parts of Semen Vaccariae of Radix Angelicae Sinensis
100 parts in 150 parts of Poria of 150 portions of Polyporus of Pericarpium Citri Reticulatae
100 parts of 100 parts of Rhizoma Acori Graminei of 100 parts of Fructus Lycii of Radix Rehmanniae Preparata
50 parts of Pheretimas
(1) Radix Codonopsis, the Radix Astragali, that Radix Angelicae Sinensis powder is broken into fine powder is standby;
(2) Lignum Aquilariae Resinatum, Semen Vaccariae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Polyporus, Poria, Radix Rehmanniae Preparata, Fructus Lycii, Rhizoma Acori Graminei, Pheretima are added 8 times of water gagings and decoct 2 times, 2 hours for the first time, each 1 hour later on, filter, merging filtrate is condensed into clear paste; Add ethanol and make and contain alcohol amount and reach 75% (V/V) in clear paste, cold preservation 24 hours filters the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature 60 be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) with step (2) gained clear paste and step (1) gained fine powder mixing, drying is ground into dry powder, adds right amount of auxiliary materials after making dry powder, and mixing is granulated, and is encapsulated, promptly.
Claims (5)
1, a kind of Chinese medicine composition for the treatment of prostatic hyperplasia is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier,
Wherein said active ingredient is made by following raw materials according:
120-360 parts of 50-200 parts of Lignum Aquilariae Resinatum of 50-200 parts of Radixs Astragali of Radix Codonopsis
100-300 parts of 100-300 parts of Rhizoma Atractylodis Macrocephalaes of 50-200 parts of Semen Vaccariae of Radix Angelicae Sinensis
50-200 parts in 150-200 parts of Poria of 100-300 parts of Polyporus of Pericarpium Citri Reticulatae
50-200 parts of 50-200 parts of Rhizoma Acori Graminei of 50-200 parts of Fructus Lycii of Radix Rehmanniae Preparata
50-200 parts of Pheretimas.
2, a kind of Chinese medicine composition for the treatment of prostatic hyperplasia according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
160 parts of 80 portions of Lignum Aquilariae Resinatum of 80 parts of Radixs Astragali of Radix Codonopsis
150 parts of 150 parts of Rhizoma Atractylodis Macrocephalaes of 80 parts of Semen Vaccariae of Radix Angelicae Sinensis
100 parts in 150 parts of Poria of 150 portions of Polyporus of Pericarpium Citri Reticulatae
100 parts of 100 parts of Rhizoma Acori Graminei of 100 parts of Fructus Lycii of Radix Rehmanniae Preparata
50 parts of Pheretimas.
3, according to the described a kind of Chinese medicine composition for the treatment of prostatic hyperplasia of claim 1-2, it is characterized in that adopting following method to make:
(1) Radix Codonopsis, the Radix Astragali, that Radix Angelicae Sinensis powder is broken into fine powder is standby;
(2) Lignum Aquilariae Resinatum, Semen Vaccariae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Polyporus, Poria, Radix Rehmanniae Preparata, Fructus Lycii, Rhizoma Acori Graminei, Pheretima are added 8 times of water gagings and decoct 2 times, 2 hours for the first time, each 1 hour later on, filter, merging filtrate is condensed into clear paste; Add ethanol and make and contain alcohol amount and reach 75% (V/V) in clear paste, cold preservation 24 hours filters the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature 60 be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) with step (2) gained clear paste and step (1) gained fine powder mixing, drying is ground into dry powder, mixes with the conventional adjunct ingredient of medicine acceptable, can obtain corresponding different concrete dosage form.
4, according to any one described a kind of Chinese medicine composition for the treatment of prostatic hyperplasia among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations.
5, according to the described a kind of Chinese medicine composition for the treatment of prostatic hyperplasia of claim 5, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810101176A CN101518603A (en) | 2008-02-28 | 2008-02-28 | Traditional Chinese medical composition used for treating prostatic hyperplasia and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810101176A CN101518603A (en) | 2008-02-28 | 2008-02-28 | Traditional Chinese medical composition used for treating prostatic hyperplasia and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463408A (en) * | 2013-08-08 | 2013-12-25 | 车艳艳 | Prostate disease treatment drug tea |
| CN104398908A (en) * | 2014-11-16 | 2015-03-11 | 陈爱华 | Chinese medicinal composition for treatment of benign prostatic hyperplasia, preparation method and application thereof |
| CN104524109A (en) * | 2014-12-30 | 2015-04-22 | 周连才 | Medicine for treating kidney-yang deficiency involution form benign prostatic hyperplasia and preparing method |
| CN109700891A (en) * | 2019-03-11 | 2019-05-03 | 山西中医药大学 | A kind of pharmaceutical composition of anti-prostatic hyperplasia |
-
2008
- 2008-02-28 CN CN200810101176A patent/CN101518603A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463408A (en) * | 2013-08-08 | 2013-12-25 | 车艳艳 | Prostate disease treatment drug tea |
| CN103463408B (en) * | 2013-08-08 | 2015-06-17 | 车艳艳 | Prostate disease treatment drug tea |
| CN104398908A (en) * | 2014-11-16 | 2015-03-11 | 陈爱华 | Chinese medicinal composition for treatment of benign prostatic hyperplasia, preparation method and application thereof |
| CN104524109A (en) * | 2014-12-30 | 2015-04-22 | 周连才 | Medicine for treating kidney-yang deficiency involution form benign prostatic hyperplasia and preparing method |
| CN109700891A (en) * | 2019-03-11 | 2019-05-03 | 山西中医药大学 | A kind of pharmaceutical composition of anti-prostatic hyperplasia |
| CN109700891B (en) * | 2019-03-11 | 2021-07-02 | 山西中医药大学 | Pharmaceutical composition for resisting prostatic hyperplasia |
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Open date: 20090902 |