CN101513518B - Chinese medicinal composition for treating mammary gland hyperplasia - Google Patents
Chinese medicinal composition for treating mammary gland hyperplasia Download PDFInfo
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- CN101513518B CN101513518B CN2009101308659A CN200910130865A CN101513518B CN 101513518 B CN101513518 B CN 101513518B CN 2009101308659 A CN2009101308659 A CN 2009101308659A CN 200910130865 A CN200910130865 A CN 200910130865A CN 101513518 B CN101513518 B CN 101513518B
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Abstract
The invention relates to Chinese medicinal composition for treating mammary gland hyperplasia, which is prepared from sparganium, Cyperus Rotundus L., radix paeoniae rubrathe, radix bupleuri, curcuma tuber, muscardine silkworm, olibanum, Chinese honeylocust spine, fructus trichosanthes, Chinese angelica, milettia reticulate and caulis Mahoniae, compared with prior art, the invention has effect of soothing the liver, resolving depression, softening hardness, dissipating binds, resolving stasis and relieving pain, does not have toxic and side effect, has simple production technology, and has excellent effect in mammary gland disease treatment.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition that is used for the treatment of cyclomastopathy, belong to technical field of traditional Chinese medicine pharmacy.
Technical background
Cyclomastopathy is the modal cystic hyperplasia of breast of women, has the women of 70%-80% that in various degree cyclomastopathy is all arranged according to investigations approximately, is more common in the 25-45 women in year.Sickness rate that in the last few years should disease is the trend that rises year by year, and the age claims the trend of becoming younger; Become a big class disease of harm women life and health.The treatment cyclomastopathy mainly is divided into doctor trained in Western medicine, the traditional Chinese medical science and operative treatment at present.Doctor trained in Western medicine concentrates on hormone therapy mostly in this disease of treatment, and side effect is big, curative effect instability, and relapse rate height, and curative effect is undesirable.Surgical operation is cured the symptoms, not the disease, and easily causes the body damage, and very easily recurrence.The traditional Chinese medical science is many with depressed liver-energy dispersing and QI regulating aspect the treatment cyclomastopathy, blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating is main, common this sick Chinese patent medicine of treatment mainly contains RUKANG PIAN, RUKUAIXIAO PIAN, RUHE SANJIE PIAN, the peaceful sheet of breast etc. on the market, the disease wart of each kind is all incomplete same, the adaptation population is subjected to certain limitation, and these kinds all exist defectives such as curative effect is not ideal enough, easy recurrence.
Summary of the invention
The objective of the invention is at the existing above-mentioned defective of state of the art, by excavating the abundant Chinese medicine resource of motherland, in conjunction with our clinical application experience for many years, sum up said composition, for the clinical treatment cyclomastopathy provides a kind of safe and effective, stable curative effect, cure rate height, and Chinese medicine composition without any side effects.
Theory of Chinese medical science think cyclomastopathy be the Liver Channel QI-blood circulation smooth due to; How by worry impairing spleen, angry impairing the liver, depression of liver-QI, stagnation of QI due to depression of the liver; Or worry impairing spleen, dysfunction of the spleen in transportation accumulates in the phlegm-damp, so that liver spleen two wounds, and mental disorder is tied mutually, and the stasis of blood stagnates and in bulk; Treating then unobstructed with QI-blood circulation is principle.Chinese medicine composition of the present invention is on this basis in conjunction with designer's clinical practice for many years, dialectically combine with differential diagnosis of diseases, by to motherland's Chinese medicine resource selected making in addition, medicine material in the side amounts to 12 flavors by rhizoma sparganic, Rhizoma Cyperi, Radix Paeoniae Rubra, Radix Bupleuri, Radix Curcumae, Bombyx Batryticatus, Olibanum, Spina Gleditsiae, Pericarpium Trichosanthis, Radix Angelicae Sinensis, Caulis Spatholobi, Caulis Mahoniae and forms, full side has dispersing the stagnated live-QI to relieve the stagnation of QI, hard masses softening and resolving, the effect of blood-activating analgetic, aspect the treatment of cyclomastopathy, fabulous effect is being arranged, can significantly reduce or eliminate of the threat of this type of disease WomanHealth.
The weight proportion that constitutes each raw material of Chinese medicine composition of the present invention is: a rhizoma sparganic 10-200 unit of weight, a Rhizoma Cyperi 10-200 unit of weight, a Radix Paeoniae Rubra 10-200 unit of weight, a Radix Bupleuri 10-130 unit of weight, a Radix Curcumae 10-130 unit of weight, a Bombyx Batryticatus 10-160 unit of weight, an Olibanum 10-120 unit of weight, a Spina Gleditsiae 10-130 unit of weight, a Pericarpium Trichosanthis 10-140 unit of weight, a Radix Angelicae Sinensis 10-100 unit of weight, a Caulis Spatholobi 10-150 unit of weight, a Caulis Mahoniae 10-180 unit of weight.
Rhizoma sparganic, Rhizoma Cyperi are monarch drug in the said medicine prescription; Rhizoma sparganic: return liver, spleen channel.Main effect is the removing blood stasis circulation of qi promoting, the removing food stagnancy pain relieving.Yong Yu mass in the abdomen mass in the abdomen, the congestion amenorrhea.Rhizoma Cyperi: return liver, spleen, tri-jiao channel.Promoting QI circulation for relieving depression, menstruction regulating and pain relieving.Be used for breast, the side of body, the abdominal distention of stagnation of QI due to depression of the liver, breast gastral cavity painful abdominal mass is vexed, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Rhizoma sparganic, Rhizoma Cyperi can make chest congestion disappear, and QI-blood circulation is unobstructed, are the medicines commonly used of treatment cyclomastopathy, and curative effect is reliable.Radix Paeoniae Rubra: return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain; Be used for hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， mass in the abdomen stomachache, too fat to move skin infection.Radix Bupleuri: return liver, gallbladder meridian; Evacuation is brought down a fever, soothing liver-QI, yang invigorating; Be used for distending pain in the chest and hypochondrium, menoxenia, uterine prolapse.Radix Curcumae: regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge.Joining Radix Paeoniae Rubra, Radix Bupleuri, Radix Curcumae is that ministerial drug helps its dispersing the stagnated live-QI to relieve the stagnation of QI, irritability is relaxed and blood works freely, and the capable then blood of gas is capable.Bombyx Batryticatus: dissipating phlegm and resolving masses.Olibanum: go into the heart, liver, spleen channel; Promoting blood circulation and stopping pain, detumescence and promoting granulation; Be used for all pains of congestion trusted subordinate.Spina Gleditsiae: return lung, large intestine channel; Mass dissipating and swelling eliminating.Pericarpium Trichosanthis: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens; Be used for the blocked-up chest feeling of fullness, acute mastitis.Bombyx Batryticatus, Olibanum, Spina Gleditsiae, Pericarpium Trichosanthis four medicines share joins the effect that full side strengthens its blood circulation promoting and dispersing pathogen accumulation.Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving.Be used for menoxenia, the amenorrhea dysmenorrhea.Caulis Spatholobi: return liver, kidney channel.Enrich blood, invigorate blood circulation, collateral dredging.Be used for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Caulis Mahoniae: bitter, cold.Return liver, stomach, large intestine channel.Radix Angelicae Sinensis, Caulis Spatholobi, Caulis Mahoniae are share all efficacy of a drug are reached in chest, strengthen the effect of full square tube network.Full side's compatibility disappears blood stasis, and expectorant coagulates certainly and disappears, thereby the mammary gland caking day by day disappears, and causes recovery from illness.
Clinical trial
Clinical observation patient 40 examples of the present invention are used for the treatment of cyclomastopathy, outpatient's 29 examples wherein, inpatient's 11 examples.Clinical observation shows: after the patient uses this product, can alleviate clinical symptoms at short notice, and the patient's chest tuberosity, distending pain is touched a tender spot discomfort uncomfortable in chest, sx or disappearances such as depressed irritability; After the patient treats continuously, occur on inspection fully recovering or being clearly better, total effective rate of the present invention is 95%, and the dispersing the stagnated live-QI to relieve the stagnation of QI of this product is described, hard masses softening and resolving, and the blood-activating analgetic effect is definite.In the clinical observation process, do not find that the patient has untoward reaction and anaphylaxis, illustrate that this product is safe and effective.
Model case:
1,47 years old patient of XXX woman had pain during the bilateral breast before 2 years, and existing disease: two newborn pain, character are twinge, are difficult for alleviating, and idol has susceptible to lose temper due to restlessness, insomnia and dreamful sleep.Once used multiple Drug therapy, but curative effect is not obvious.Be the bilateral breast hypertrophy on inspection, tcm diagnosis is a nodules of the breast, takes capsule of the present invention after 1 course of treatment, and left newborn pain disappears, and right newborn pain obviously alleviates, and the lump scope is obviously dwindled, take 2 courses of treatment again after symptom all disappear, fully recover on inspection.
2,33 years old patient of XXX woman had pain during left breast before 3 months, and lump is arranged, and the pain increased for left side breast recently, and lump increases; Once used multiple Drug therapy, but curative effect is not obvious.Be cyclomastopathy on inspection.Take capsule of the present invention after 1 course of treatment, left newborn pain disappears, cyclomastopathy recovery from illness on inspection.
3,35 years old bilateral mastalgia before 1 month of XXX woman, but spontaneous remission, touching two breasts has lump, and pain increases the weight of recently, and feels irritated irritability, insomnia and dreamful sleep, fullness and distention in the chest and hypochondrium, menstrual blood volume is few.Be cyclomastopathy on inspection, take capsule of the present invention after 1 course of treatment, left newborn pain disappears, and right newborn pain obviously alleviates, take 1 course of treatment again after symptom all disappear cyclomastopathy recovery from illness on inspection.
4,32 years old right breast distending pain before 2 months of XXX woman touched lump, and pain increases the weight of recently, fullness and distention in the chest and hypochondrium, and menstrual blood volume is few.Be two cyclomastopathy on inspection, take capsule of the present invention after 2 courses of treatment, right breast pain disappears, and lump disappears substantially, cyclomastopathy recovery from illness on inspection.
The specific embodiment:
Embodiment 1
Prescription
65 parts of 100 parts of Radix Bupleuri of 100 parts of Radix Paeoniae Rubra of 100 portions of Rhizoma Cyperis of rhizoma sparganic
65 parts of 60 parts of Spina Gleditsiaes of 80 parts of Olibanums of 65 parts of Bombyx Batryticatus of Radix Curcumae
90 parts of 75 parts of Caulis Mahoniaes of 50 portions of Caulis Spatholobis of 70 parts of Radix Angelicae Sinensis of Pericarpium Trichosanthis
Preparation technology
Get Bombyx Batryticatus, Olibanum, be ground into fine powder, standby; Get all the other 10 flavor medical materials such as rhizoma sparganic, decoct with water secondary, each 2 hours, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, collecting decoction filters, and concentrates and drying under reduced pressure (0.085Mp, 60 ℃), gets dry extract, and pulverizes, and crosses 100 mesh sieves, and is standby; With above-mentioned two kinds of fine powders and appropriate amount of starch mixing, to granulate, drying adds magnesium stearate, and mixing is encapsulated, promptly gets capsule of the present invention.
Embodiment 2
Prescription
80 parts of 60 parts of Radix Bupleuri of 150 parts of Radix Paeoniae Rubra of 150 portions of Rhizoma Cyperis of rhizoma sparganic
80 parts of 80 parts of Spina Gleditsiaes of 100 parts of Olibanums of 80 parts of Bombyx Batryticatus of Radix Curcumae
110 parts of 100 parts of Caulis Mahoniaes of 70 portions of Caulis Spatholobis of 90 parts of Radix Angelicae Sinensis of Pericarpium Trichosanthis
Preparation technology
Get Bombyx Batryticatus, Olibanum, be ground into fine powder, standby; Get all the other 10 flavor medical materials such as rhizoma sparganic, decoct with water secondary, each 2 hours, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, collecting decoction filters, and concentrates and drying under reduced pressure (0.085Mp, 60 ℃), gets dry extract, and pulverizes, and crosses 100 mesh sieves, and is standby; With above-mentioned two kinds of fine powders and appropriate amount of starch mixing, to granulate, drying adds magnesium stearate, mixing, tabletting promptly gets tablet of the present invention.
Embodiment 3
Prescription
90 parts of 80 parts of Radix Bupleuri of 110 parts of Radix Paeoniae Rubra of 110 portions of Rhizoma Cyperis of rhizoma sparganic
90 parts of 90 parts of Spina Gleditsiaes of 85 parts of Olibanums of 90 parts of Bombyx Batryticatus of Radix Curcumae
100 parts of 95 parts of Caulis Mahoniaes of 60 portions of Caulis Spatholobis of 85 parts of Radix Angelicae Sinensis of Pericarpium Trichosanthis
Preparation technology
Get Bombyx Batryticatus, Olibanum, be ground into fine powder, standby; Get all the other 10 flavor medical materials such as rhizoma sparganic, decoct with water secondary, each 2 hours, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, collecting decoction filters, and concentrates and drying under reduced pressure (0.085Mp, 60 ℃), gets dry extract, and pulverizes, and crosses 100 mesh sieves, and is standby; With above-mentioned two kinds of fine powders and an amount of dextrin mixing, granulate, drying, pack promptly gets granule of the present invention.
Embodiment 4
Prescription
65 parts of 100 parts of Radix Bupleuri of 100 parts of Radix Paeoniae Rubra of 100 portions of Rhizoma Cyperis of rhizoma sparganic
65 parts of 60 parts of Spina Gleditsiaes of 80 parts of Olibanums of 65 parts of Bombyx Batryticatus of Radix Curcumae
90 parts of 75 parts of Caulis Mahoniaes of 50 portions of Caulis Spatholobis of 70 parts of Radix Angelicae Sinensis of Pericarpium Trichosanthis
Preparation technology
Get Bombyx Batryticatus, Olibanum, be ground into fine powder, standby; Get all the other 10 flavor medical materials such as rhizoma sparganic, decoct with water secondary, each 2 hours, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, collecting decoction filters, and concentrates and drying under reduced pressure (0.085Mp, 60 ℃), gets dry extract, and pulverizes, and crosses 100 mesh sieves, and is standby; With above-mentioned two kinds of fine powders and appropriate amount of starch mixing, to granulate, drying adds magnesium stearate, mixing, tabletting promptly gets tablet of the present invention.
Embodiment 5
Prescription
65 parts of 100 parts of Radix Bupleuri of 100 parts of Radix Paeoniae Rubra of 100 portions of Rhizoma Cyperis of rhizoma sparganic
65 parts of 60 parts of Spina Gleditsiaes of 80 parts of Olibanums of 65 parts of Bombyx Batryticatus of Radix Curcumae
90 parts of 75 parts of Caulis Mahoniaes of 50 portions of Caulis Spatholobis of 70 parts of Radix Angelicae Sinensis of Pericarpium Trichosanthis
Preparation technology
Get Bombyx Batryticatus, Olibanum, be ground into fine powder, standby; Get all the other 10 flavor medical materials such as rhizoma sparganic, decoct with water secondary, each 2 hours, add 10 times of water gagings for the first time, add 8 times of water gagings for the second time, collecting decoction filters, and concentrates and drying under reduced pressure (0.085Mp, 60 ℃), gets dry extract, and pulverizes, and crosses 100 mesh sieves, and is standby; With above-mentioned two kinds of fine powders and an amount of dextrin mixing, granulate, drying, pack promptly gets granule of the present invention.
Claims (4)
1. a Chinese medicine composition that is used for the treatment of cyclomastopathy is characterized in that it is the Chinese medicine preparation of being processed into by following materials of weight proportions medicine: a rhizoma sparganic 100-150 unit of weight, a Rhizoma Cyperi 100-150 unit of weight, a Radix Paeoniae Rubra 60-100 unit of weight, a Radix Bupleuri 65-90 unit of weight, a Radix Curcumae 65-90 unit of weight, a Bombyx Batryticatus 80-100 unit of weight, an Olibanum 60-90 unit of weight, a Spina Gleditsiae 65-90 unit of weight, a Pericarpium Trichosanthis 70-90 unit of weight, a Radix Angelicae Sinensis 50-70 unit of weight, a Caulis Spatholobi 75-100 unit of weight, a Caulis Mahoniae 90-110 unit of weight.
2. the best proportioning of traditional Chinese medicinal composition raw materials according to claim 1 is: 100 parts of rhizoma sparganic, 100 parts of Rhizoma Cyperis, 100 parts of Radix Paeoniae Rubra, 65 parts of Radix Bupleuri, 65 parts of Radix Curcumaes, 80 parts of Bombyx Batryticatus, 60 parts of Olibanums, 65 parts of Spina Gleditsiaes, 70 parts of Pericarpium Trichosanthiss, 50 parts of Radix Angelicae Sinensis, 75 parts of Caulis Spatholobis, 90 parts of Caulis Mahoniaes.
3. the Chinese medicine composition of treatment cyclomastopathy according to claim 1 and 2 is characterized in that: described Chinese medicine composition is an acceptable forms on the pharmaceutics, is selected from tablet, granule or capsule.
4. method for preparing the Chinese medicine composition of the described treatment cyclomastopathy of claim 3 is characterized in that: gets Bombyx Batryticatus, Olibanum, is ground into fine powder, and standby; Get rhizoma sparganic, Rhizoma Cyperi, Radix Paeoniae Rubra, Radix Bupleuri, Radix Curcumae, Spina Gleditsiae, Pericarpium Trichosanthis, Radix Angelicae Sinensis, Caulis Spatholobi, Caulis Mahoniae totally 10 flavor medical materials, decoct with water twice, each 2 hours, add for the first time 10 times of water gagings, add 8 times of water gagings, collecting decoction for the second time, filter, concentrate ,-0.085Mp, drying under reduced pressure under 60 ℃ the condition, get dry extract, pulverize, cross 100 mesh sieves, standby; With above-mentioned two kinds of fine powders and each dosage form proper auxiliary materials mixing, to granulate, drying is made each dosage form.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101308659A CN101513518B (en) | 2009-04-16 | 2009-04-16 | Chinese medicinal composition for treating mammary gland hyperplasia |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101308659A CN101513518B (en) | 2009-04-16 | 2009-04-16 | Chinese medicinal composition for treating mammary gland hyperplasia |
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| CN101513518A CN101513518A (en) | 2009-08-26 |
| CN101513518B true CN101513518B (en) | 2011-12-07 |
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| CN2009101308659A Active CN101513518B (en) | 2009-04-16 | 2009-04-16 | Chinese medicinal composition for treating mammary gland hyperplasia |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP5966999B2 (en) | 2013-03-29 | 2016-08-10 | マツダ株式会社 | Multi-cylinder engine controller |
| CN105106852A (en) * | 2015-09-17 | 2015-12-02 | 李朕 | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and breast cancer |
| CN106110209A (en) * | 2016-08-09 | 2016-11-16 | 李双双 | A kind of Chinese medicine preparation treating cyclomastopathy |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1907459A (en) * | 2005-08-02 | 2007-02-07 | 暴永贤 | Medicine for treating hyperplasia of mammary glands and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1907459A (en) * | 2005-08-02 | 2007-02-07 | 暴永贤 | Medicine for treating hyperplasia of mammary glands and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘丽云.乳腺癌证治的中医文献研究.《中国优秀硕士学位论文全文数据库》.医药卫生科技辑,2009,(第01期),E056-337. * |
| 赵殿法等.自拟消癖饮治疗乳腺增生病56例疗效观察.《新疆中医药》.2005,第23卷(第6期),第18-19页. * |
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