CN101489471B - 利用检测微血管血液含量早期增大来识别异常组织的装置 - Google Patents
利用检测微血管血液含量早期增大来识别异常组织的装置 Download PDFInfo
- Publication number
- CN101489471B CN101489471B CN200780026888.4A CN200780026888A CN101489471B CN 101489471 B CN101489471 B CN 101489471B CN 200780026888 A CN200780026888 A CN 200780026888A CN 101489471 B CN101489471 B CN 101489471B
- Authority
- CN
- China
- Prior art keywords
- light
- collection
- tissue
- fiber
- lens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00096—Optical elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
- A61B1/00167—Details of optical fibre bundles, e.g. shape or fibre distribution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/31—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes, colonoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
- A61B5/0265—Measuring blood flow using electromagnetic means, e.g. electromagnetic flowmeter
- A61B5/027—Measuring blood flow using electromagnetic means, e.g. electromagnetic flowmeter using catheters
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Endoscopes (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80195406P | 2006-05-19 | 2006-05-19 | |
| US80194706P | 2006-05-19 | 2006-05-19 | |
| US60/801,954 | 2006-05-19 | ||
| US60/801,947 | 2006-05-19 | ||
| US11/604,653 | 2006-11-27 | ||
| US11/604,659 US20070129615A1 (en) | 2005-10-27 | 2006-11-27 | Apparatus for recognizing abnormal tissue using the detection of early increase in microvascular blood content |
| US11/604,653 US20070179368A1 (en) | 2005-10-27 | 2006-11-27 | Method of recognizing abnormal tissue using the detection of early increase in microvascular blood content |
| US11/604,659 | 2006-11-27 | ||
| PCT/US2007/012359 WO2007136880A2 (en) | 2006-05-19 | 2007-05-21 | Method & apparatus for recognizing abnormal tissue using the detection of early increase in microvascular blood content |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101489471A CN101489471A (zh) | 2009-07-22 |
| CN101489471B true CN101489471B (zh) | 2014-08-27 |
Family
ID=38723920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200780026888.4A Expired - Fee Related CN101489471B (zh) | 2006-05-19 | 2007-05-21 | 利用检测微血管血液含量早期增大来识别异常组织的装置 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2020910B1 (https=) |
| JP (2) | JP5616058B2 (https=) |
| CN (1) | CN101489471B (https=) |
| AU (1) | AU2007254086B2 (https=) |
| CA (1) | CA2653040A1 (https=) |
| WO (1) | WO2007136880A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090203977A1 (en) * | 2005-10-27 | 2009-08-13 | Vadim Backman | Method of screening for cancer using parameters obtained by the detection of early increase in microvascular blood content |
| US9314164B2 (en) | 2005-10-27 | 2016-04-19 | Northwestern University | Method of using the detection of early increase in microvascular blood content to distinguish between adenomatous and hyperplastic polyps |
| EP2385786A4 (en) * | 2009-01-08 | 2013-07-03 | American Biooptics Llc | PROBE DEVICE FOR DETECTING TISSUE ANOMALIES |
| US9885834B2 (en) | 2009-01-08 | 2018-02-06 | Northwestern University | Probe apparatus for measuring depth-limited properties with low-coherence enhanced backscattering |
| JP2012237595A (ja) | 2011-05-10 | 2012-12-06 | Sumitomo Electric Ind Ltd | 光トモグラフィ装置 |
| JP5623348B2 (ja) * | 2011-07-06 | 2014-11-12 | 富士フイルム株式会社 | 内視鏡システム、内視鏡システムのプロセッサ装置、及び内視鏡システムの作動方法 |
| WO2013090658A1 (en) | 2011-12-14 | 2013-06-20 | The Trustees Of The University Of Pennsylvania | Fiber optic flow and oxygenation monitoring using diffuse correlation and reflectance |
| EP2823747A4 (en) * | 2012-03-07 | 2015-04-22 | Olympus Corp | PROBE |
| JP6205346B2 (ja) * | 2012-03-07 | 2017-09-27 | オリンパス株式会社 | 光学測定装置およびファイババンドルの対応付け方法 |
| WO2014042156A1 (ja) * | 2012-09-13 | 2014-03-20 | オリンパス株式会社 | 測定プローブおよび生体光学測定システム |
| JP6358573B2 (ja) * | 2014-05-15 | 2018-07-18 | 国立大学法人浜松医科大学 | 乳房計測装置の作動方法及び乳房計測装置 |
| JP6371613B2 (ja) * | 2014-07-09 | 2018-08-08 | オリンパス株式会社 | 画像処理装置、画像処理方法、及び画像処理プログラム |
| DE112015005176T5 (de) | 2014-12-12 | 2017-08-24 | Olympus Corporation | Messsonde und bio-optisches Messsystem |
| JP2017018483A (ja) * | 2015-07-14 | 2017-01-26 | オリンパス株式会社 | 医療用プローブ |
| CA3102138A1 (en) | 2018-06-08 | 2019-12-12 | East Carolina University | Determining peripheral oxygen saturation (spo2) and hemoglobin concentration using multi-spectral laser imaging (msli) methods and systems |
| WO2020198315A1 (en) | 2019-03-26 | 2020-10-01 | East Carolina University | Near-infrared fluorescence imaging for blood flow and perfusion visualization and related systems and computer program products |
| WO2022020207A1 (en) | 2020-07-24 | 2022-01-27 | Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America | Image reconstruction and endoscopic tracking |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6320184B1 (en) * | 1998-07-09 | 2001-11-20 | Avl List Gmbh | Optoelectric measuring device for monitoring combustion processes |
| US6571118B1 (en) * | 1998-05-04 | 2003-05-27 | Board Of Regents, The University Of Texas System | Combined fluorescence and reflectance spectroscopy |
| US6922583B1 (en) * | 1997-10-10 | 2005-07-26 | Massachusetts Institute Of Technology | Method for measuring tissue morphology |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6198532B1 (en) * | 1991-02-22 | 2001-03-06 | Applied Spectral Imaging Ltd. | Spectral bio-imaging of the eye |
| US6485413B1 (en) * | 1991-04-29 | 2002-11-26 | The General Hospital Corporation | Methods and apparatus for forward-directed optical scanning instruments |
| US5799656A (en) * | 1996-10-21 | 1998-09-01 | The Research Foundation Of City College Of New York | Optical imaging of breast tissues to enable the detection therein of calcification regions suggestive of cancer |
| ATE391451T1 (de) * | 1998-01-26 | 2008-04-15 | Massachusetts Inst Technology | Endoskop zur erfassung von fluoreszenzbilder |
| CA2343401C (en) * | 1998-09-11 | 2009-01-27 | Spectrx, Inc. | Multi-modal optical tissue diagnostic system |
| US6353226B1 (en) * | 1998-11-23 | 2002-03-05 | Abbott Laboratories | Non-invasive sensor capable of determining optical parameters in a sample having multiple layers |
| US6404497B1 (en) * | 1999-01-25 | 2002-06-11 | Massachusetts Institute Of Technology | Polarized light scattering spectroscopy of tissue |
| US20040147843A1 (en) * | 1999-11-05 | 2004-07-29 | Shabbir Bambot | System and method for determining tissue characteristics |
| JP4067696B2 (ja) * | 1999-05-21 | 2008-03-26 | 富士フイルム株式会社 | 蛍光強度比較出力方法および蛍光診断情報出力装置 |
| JP2000325295A (ja) * | 1999-05-21 | 2000-11-28 | Fuji Photo Film Co Ltd | 蛍光診断情報出力方法および装置 |
| WO2001008552A1 (en) * | 1999-08-03 | 2001-02-08 | Biophysica, Llc | Spectroscopic systems and methods for detecting tissue properties |
| AU4022801A (en) * | 1999-09-23 | 2001-04-24 | Richard G. Nadeau | Medical applications of orthogonal polarization spectral imaging |
| US6639674B2 (en) * | 2000-03-28 | 2003-10-28 | Board Of Regents, The University Of Texas System | Methods and apparatus for polarized reflectance spectroscopy |
| US6697652B2 (en) * | 2001-01-19 | 2004-02-24 | Massachusetts Institute Of Technology | Fluorescence, reflectance and light scattering spectroscopy for measuring tissue |
| JP3762646B2 (ja) * | 2001-02-01 | 2006-04-05 | オリンパス株式会社 | 蛍光観察装置 |
| US7217266B2 (en) * | 2001-05-30 | 2007-05-15 | Anderson R Rox | Apparatus and method for laser treatment with spectroscopic feedback |
| US7404929B2 (en) * | 2002-01-18 | 2008-07-29 | Newton Laboratories, Inc. | Spectroscopic diagnostic methods and system based on scattering of polarized light |
| US8849379B2 (en) * | 2002-04-22 | 2014-09-30 | Geelux Holdings, Ltd. | Apparatus and method for measuring biologic parameters |
| US7390298B2 (en) * | 2003-01-06 | 2008-06-24 | City Of Hope | Expandable surgical retractor for internal body spaces approached with minimally invasive incisions or through existing orifices |
| WO2004083944A2 (en) * | 2003-03-18 | 2004-09-30 | The General Hospital Corporation | Polarized light devices and methods |
| US20060155178A1 (en) * | 2004-03-26 | 2006-07-13 | Vadim Backman | Multi-dimensional elastic light scattering |
-
2007
- 2007-05-21 AU AU2007254086A patent/AU2007254086B2/en not_active Ceased
- 2007-05-21 EP EP07795266.1A patent/EP2020910B1/en active Active
- 2007-05-21 JP JP2009512139A patent/JP5616058B2/ja not_active Expired - Fee Related
- 2007-05-21 CA CA002653040A patent/CA2653040A1/en active Pending
- 2007-05-21 CN CN200780026888.4A patent/CN101489471B/zh not_active Expired - Fee Related
- 2007-05-21 WO PCT/US2007/012359 patent/WO2007136880A2/en not_active Ceased
-
2012
- 2012-10-24 JP JP2012235160A patent/JP5670982B2/ja not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6922583B1 (en) * | 1997-10-10 | 2005-07-26 | Massachusetts Institute Of Technology | Method for measuring tissue morphology |
| US6571118B1 (en) * | 1998-05-04 | 2003-05-27 | Board Of Regents, The University Of Texas System | Combined fluorescence and reflectance spectroscopy |
| US6320184B1 (en) * | 1998-07-09 | 2001-11-20 | Avl List Gmbh | Optoelectric measuring device for monitoring combustion processes |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2020910A4 (en) | 2014-01-08 |
| CA2653040A1 (en) | 2007-11-29 |
| WO2007136880A2 (en) | 2007-11-29 |
| AU2007254086B2 (en) | 2013-03-21 |
| JP5670982B2 (ja) | 2015-02-18 |
| JP5616058B2 (ja) | 2014-10-29 |
| JP2013048914A (ja) | 2013-03-14 |
| CN101489471A (zh) | 2009-07-22 |
| WO2007136880A3 (en) | 2008-04-24 |
| EP2020910A2 (en) | 2009-02-11 |
| JP2009537285A (ja) | 2009-10-29 |
| AU2007254086A1 (en) | 2007-11-29 |
| EP2020910B1 (en) | 2019-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140827 Termination date: 20200521 |