The relieving the effect of alcohol and suppress method and the goods that COF absorbs of a kind of producing ion release type gelating product
Technical field
The present invention relates to food technology field, particularly relate to relieving the effect of alcohol and suppressing method and the goods that COF absorbs of a kind of producing ion release type gelating product.
Background technology
Along with the raising of The development in society and economy and people's living standard, and spirits culture is in the influence of China, and it is very general drinking in China, but drink the person had very big infringement, and particularly a large amount of drinks.Therefore occasion in social activity must be drunk again sometimes, invents a kind ofly can relieve the effect of alcohol and reduce the product of ethanol to injury of human, and the needs of drinking in the time of can satisfying social activity can be protected healthy again.Relieving the effect of alcohol at present has three kinds of modes, and the one, reduce or suppress the absorption of ethanol; The 2nd, by accelerating ethanol metabolism in vivo becoming water and carbon dioxide, want to accelerate activity and the content that ethanol metabolism in vivo need increase L-AD and acetaldehyde dehydrogenase, this process is slower.The 3rd, by lung's exhalation, RE (diuresis and great quantity of water drinking) and skin perspiration (drink hot water and raising indoor temperature) eliminating, this approach at most only accounts for 10% of absorption ethanol total amount, is not the best approach that relieves the effect of alcohol.And suppress or reduce the absorption of ethanol, the effect of can faster performance relieving the effect of alcohol.
It mainly is to have Chinese medicine materials such as FI puerariae, the root of kudzu vine, glossy ganoderma, Raisin Tree Seed, Radix Isatidis to make that some disintoxicating products are arranged in the market, significant feature mechanism is the hepatoprotective effect by oxidation and removing free radicals, might accelerate ethanol metabolism in vivo after absorbing in vivo, little to the inhibitory action that ethanol absorbs.
Earlier edible oily food before the method for pre-preventing drunkenness among the people is being drunk exactly, as fat meat, pork leg etc., or milk drink, utilize the fatty stodgy characteristic protection stomach in the food, to prevent the ethanol infiltration coat of the stomach.In addition, the shagreen of guava part also can be brought into play same effect.Empty stomach is drunk or carbonated drink, soda water and wine is drunk together, can make stomach accelerate the infiltration rate of ethanol under the situation that does not have protection, makes liver have little time detoxifcation, and concentration of alcohol increases rapidly and causes drunk.
But said method is not clearly to the pre-preventing drunkenness and the effect of relieving the effect of alcohol, and effect slowly, though some mode has been utilized and suppressed the principle that ethanol absorbs and reach the effect of relieving the effect of alcohol, effect is also not obvious; Though the method and the product of the pre-preventing drunkenness that suppresses the ethanol absorption have been arranged at present, also only obvious to liquor and foreign wine effect, and the relieving alcoholism and preventing drunkenness of red wine is not had obvious effects.
Summary of the invention
At the deficiency in the above-mentioned technical field; the invention provides relieving the effect of alcohol and suppressing method and the goods that COF absorbs of a kind of producing ion release type gelating product; particularly suppress ethanol absorption in vivo in the red wine; to reach the effect of relieving the effect of alcohol and increasing capacity for liquor; also play simultaneously liver-protective effect, in addition also clearly to the absorption that suppresses liquor and antialcoholism action.
The relieving the effect of alcohol and suppress the method that COF absorbs of a kind of producing ion release type gelating product, it is characterized in that: human body is taken in and is contained calcium source and the mixture that becomes the glue material, under the effect of acid red wine or hydrochloric acid in gastric juice, ethanol in the stomach or COF with become glue material and calcium ion in conjunction with the formation plural gel, described one-tenth glue material is pectin or alginate.
Described pectin is a kind of of HM or LM.
Described alginate is sodium alginate, potassium alginate or ammonium alginate.
Described calcium source is calcium sulfate or calcium monohydrogen phosphate.
Relieving the effect of alcohol and suppress the goods that method that COF absorbs makes according to above-mentioned producing ion release type gelating product, it is characterized in that comprising into glue material, acid-base modifier, calcium source and school flavor agent, becoming glue material, calcium source, school flavor agent weight ratio is 1: 0.01-0.3: 0-40, the consumption of acid-base modifier are that pH transfers at 6.5-8.5.
Described one-tenth glue material, calcium source, school flavor agent weight ratio are 1:0.07-0.2:5-20, and best pH is 6.9-7.5.
Described acid-base modifier is a kind of in sodium acid carbonate, sodium carbonate, potash, dipotassium hydrogen phosphate, sodium hydrogen phosphate, tertiary sodium phosphate, tripotassium phosphate, natrium citricum, potassium citrate, NaOH, potassium hydroxide, gluconic acid δ lactones, sodium dihydrogen citrate, the sodium sesquicarbonate.
The flavor agent of described school is sweetener, fruits and vegetables powder and/or Juice.
Described sweetener is granulated sugar, glucose, sucrose, fructose, maltose, lactose, maltitol, lactitol, xylitol, sorbierite, antierythrite, one or more of dithiothreitol (DTT); Described fruits and vegetables powder, Juice comprises apple, strawberry, cherry, "Hami" melon, banana, lichee, panax ginseng fruit, mango, pomegranate, olive, sugarcane, hawthorn, pears, oranges and tangerines, watermelon, muskmelon, peach, apricot, passionflower, Kiwi berry, shaddock, pineapple, wild jujube, beet, tomato, carrot, cucumber, pumpkin, wax gourd, Chinese cabbage, cabbage, cauliflower, persimmon, balsam pear, water chestnut, ternip, eggplant, green pepper, celery, spinach, bright lotus root, garlic, one or more compound fruit and vegetable powder of onion, Juice.
Said products at pre-preventing drunkenness, relieve the effect of alcohol and suppress application aspect the absorption of COF.
The present invention adopts scientific principles, under acid red wine or hydrochloric acid in gastric juice condition, discharge calcium ion, make ethanol or COF be combined into plural gel shape thing with becoming the glue material, make free ethanol and COF reduction in the stomach, reduce interior absorption of body of ethanol and COF, thereby play the effect of sobering up and improving capacity for liquor and the absorption of control COF.
The present invention is based on the ion freezing mechanism of pectin and alginate, pectin and alginate are the most frequently used edible gels, particularly LM or alginate solution are under the situation that calcium ion exists, molecule crosslinked formation gel, under the neutral environment condition, calcium in the calcium source is in bonding state, therefore product is in liquid condition and can not solidifies, after mixing with the red wine of acidity, make product be in acid condition, at this moment calcium ion discharges, make pectin or alginate take place crosslinked and the formation gelling material, make free ethanol molecule form plural gel shape thing, suppress interior absorption of body of ethanol, relieve the effect of alcohol thereby reach, the effect of sobering up.
The goods that relieve the effect of alcohol provided by the invention add sweetener, fruits and vegetables powder and/or Juice as the school agent of distinguishing the flavor of, and have increased the agreeable to the taste sense and the nutritive value of these goods.
The present invention's goods that relieve the effect of alcohol can be electuary, beverage, tablet and gastric-dissolved capsule, take in these goods before drinking and can prevent drunk and improve capacity for liquor, drink after drinking into the goods that originally the relieve the effect of alcohol restoring consciouness of can relieving the effect of alcohol, and reduce the burning sensation of alcohol to stomach.These goods are because its mechanism of action also can play inhibitory action to the absorption of food, such as the absorption of control fat, cholesterol, sugar.
Goods of the present invention only run into hydrochloric acid in gastric juice or acid wine liquid could form gelinite, and after being ingested, parcel ethanol forms frangible gel in stomach and under the interaction of acid red wine or hydrochloric acid in gastric juice, and free ethanol molecule is reduced; Gel forms thicker food layer on the small intestine surface after entering small intestine, thereby the absorption of the inhibition or the ethanol that slows down reaches and relieves the effect of alcohol, increases capacity for liquor, is applicable to pre-preventing drunkenness and drunk person's treatment.External ethanol also proves the present invention's effect that goods have to be increased capacity for liquor and relieve the effect of alcohol of relieving the effect of alcohol in conjunction with test and volunteer are edible, can be used to pre-preventing drunkenness of the crowd of drinking and drunk person's treatment, can also play liver-protective effect.External COF shows this product energy and COF combination in conjunction with test, suppresses the absorption of sugar and fatty material.
Description of drawings
Fig. 1, aspiration eater drink behind the 56% strong, colourless liquor distilled from sorghum 100ml in the breath alcohol concentration (mg/100ml) in time (minute) change curve, abscissa represent the time (minute), ordinate is represented alcohol concentration (mg/100ml).
Fig. 2, aspiration eater drink behind 56% strong, colourless liquor distilled from sorghum 100ml and the 200ml sample in the breath alcohol concentration (mg/100ml) in time (minute) change curve, abscissa represent the time (minute), ordinate is represented alcohol concentration (mg/100ml).
Fig. 3, aspiration eater drink behind the 13.5% claret 200ml in the breath alcohol concentration (mg/100ml) in time (minute) change curve, abscissa represent the time (minute), ordinate is represented alcohol concentration (mg/100ml).
Fig. 4, aspiration eater drink behind 13.5% claret 200ml and the 200ml sample in the breath alcohol concentration (mg/100ml) in time (minute) change curve, abscissa represent the time (minute), ordinate is represented alcohol concentration (mg/100ml).
The specific embodiment
The present invention is described in further detail in conjunction with the embodiments.
Embodiment 1
LM 10 grams, dipotassium hydrogen phosphate 0.15 gram, calcium monohydrogen phosphate 0.75 gram, granulated sugar 150 grams, every bag 15 gram packings behind the mixed grinding.
Embodiment 2
LM 10 grams, sodium acid carbonate 0.09 gram, calcium monohydrogen phosphate 0.75 gram, granulated sugar 100 grams, pumpkin powder 30 grams dissolve in 1000ml water, every bottle of 100ml packing, high-temperature sterilization.
Embodiment 3
Ammonium alginate 10 grams, natrium citricum 0.6 gram, calcium monohydrogen phosphate 0.15 gram, granulated sugar 200 grams, pineapple powder 30 grams, every bag 15 gram packings behind the mixed grinding.
Embodiment 4
LM 10 grams, potassium hydroxide 0.02 gram, calcium monohydrogen phosphate 0.75 gram, granulated sugar 100 grams, xylitol 5 grams, wild jujube powder 30 grams dissolve in 1000ml water, every bottle of 100ml packing, high-temperature sterilization.
Embodiment 5
Potassium alginate 10 grams, sodium acid carbonate 0.06 gram, calcium sulfate 0.75 gram, granulated sugar 50 grams, glucose 50 grams, carrot meal 30 grams, every bag 15 gram packings behind the mixed grinding.
Embodiment 6
Pectin 10 grams, sodium hydrogen phosphate 0.6 gram, calcium monohydrogen phosphate 0.75, concentrated apple juice 500ml add water 500ml dissolving, every bottle of 100ml packing, high-temperature sterilization.
Embodiment 7
HM 10 grams, gluconic acid δ lactones 0.06 gram, calcium monohydrogen phosphate 3 grams, granulated sugar 100 grams, litchi powder 30 grams, every bag 15 gram packings behind the mixed grinding.
Embodiment 8
Sodium alginate 10 grams, sodium acid carbonate 0.3 gram, calcium monohydrogen phosphate 0.75 gram, mango powder 80 grams, every bag 15 gram packings behind the mixed grinding.
The experimental example effect assessment
Goods among the above embodiment are as being solid, and then the ratio that becomes the glue material to add 100ml water in 1g in the component is used for following test after dissolving fully, and liquid is directly used in test.
1. become the colloidality evaluation
Getting aforesaid liquid 5ml adding volume respectively is in the test tube of 10ml, adds 13.5%, 12% claret 5ml then respectively, shakes up immediately, observes into the glue situation after 5 minutes.Result such as table 1.
Table 1
Wine concentration |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Embodiment 4 |
Embodiment 5 |
Embodiment 6 |
Embodiment 7 |
Embodiment 8 |
13.5% |
++++ |
++++ |
+++ |
++++ |
++++ |
++++ |
++++ |
++++ |
12% |
++++ |
++++ |
+++ |
++++ |
++++ |
++++ |
++++ |
++++ |
+ expression forms gel
Above-mentioned experiment shows, the goods that relieve the effect of alcohol of the present invention add acid red and can form gelinite after drinking, can reduce ethanol free in the stomach, suppresses interior absorption of body of ethanol.
2. the ethanol conservation rate is estimated
Blank: the mixed liquor of the hydrochloric acid of 56% ethanol 1ml and 0.2mlpH=2 or 13.5% red wine 1ml and 2ml distilled water join in the 10ml test tube.
Test: the goods liquid 1ml that relieves the effect of alcohol that makes that the mixed liquor of the hydrochloric acid of 56% ethanol 1ml and 0.2mlpH=2 or 13.5% red wine 1ml add above embodiment joins mixing in the 10ml test tube, 1000RPM is centrifugal 20 minutes after 10 minutes, collect supernatant and join in the 1ml distilled water, through suitably adopting ethanol content in the gas chromatography determination liquid after the dilution.The ethanol conservation rate calculates as follows:
Ethanol conservation rate (%)=[(blank value-test value)/blank value] * 100%
Result such as table 2:
Table 2
Wine concentration |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Embodiment 4 |
Embodiment 5 |
Embodiment 6 |
Embodiment 7 |
Embodiment 8 |
13.5% |
95% |
93% |
90% |
95% |
98% |
96% |
99% |
96% |
56% |
96% |
94% |
88% |
90% |
93% |
95% |
96% |
93% |
Above-mentioned experiment showed, in the gelinite material is enclosed with ethanol, makes free amount of alcohol reduce, and ethanol conservation rate height illustrates the ethanol content height that wraps up in the gelinite.
3. to the gelling of COF
1) to the gelling of sugar: getting aforesaid liquid 5ml respectively, to add volume be in the test tube of 15ml, adds 60% sugar solubility 4ml then, adds the hydrochloric acid 1ml of pH=2 again, and mixing is observed into the glue situation after 5 minutes immediately.Result such as table 3:
Table 3
Sugar concentration |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Embodiment 4 |
Embodiment 5 |
Embodiment 6 |
60% |
++++ |
++++ |
++++ |
++++ |
++++ |
++++ |
Sugar concentration |
Embodiment 7 |
Embodiment 8 |
|
|
|
|
60% |
++++ |
++++ |
|
|
|
|
+ expression forms gel
Above-mentioned experiment shows that goods of the present invention can form gelinite after adding granulated sugar under the condition of simulation hydrochloric acid in gastric juice, has reduced free glycan molecule, therefore can suppress to delay to absorb in the sugared body.
2) the one-tenth colloidality of yolk is estimated: getting aforesaid liquid 5ml adding volume respectively is in the test tube of 15ml, adds 60% yolk solution 4ml then, adds the hydrochloric acid 1ml of pH=2 again, and mixing is observed into the glue situation after 5 minutes immediately.Result such as table 4:
Table 4
Yolk |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Embodiment 4 |
Embodiment 5 |
Embodiment 6 |
60% |
++++ |
++++ |
++++ |
++++ |
++++ |
++++ |
Yolk |
Embodiment 7 |
Embodiment 8 |
|
|
|
|
60% |
++++ |
++++ |
|
|
|
|
+ expression forms gel
Above-mentioned experiment shows that goods of the present invention can form gelinite after adding yolk under the condition of simulation hydrochloric acid in gastric juice, reduced the CHF in the yolk, therefore can suppress to delay interior absorption of body of cholesterol.
3) the one-tenth colloidality of vegetable oil is estimated: getting aforesaid liquid 5ml adding volume respectively is in the test tube of 15ml, adds vegetable oil 4ml then, adds the hydrochloric acid 1ml of pH=2 again, and mixing is observed into the glue situation after 5 minutes immediately.Result such as table 5:
Table 5
Vegetable oil |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Embodiment 4 |
Embodiment 5 |
Embodiment 6 |
100% |
++++ |
++++ |
++++ |
++++ |
++++ |
++++ |
Vegetable oil |
Embodiment 7 |
Embodiment 8 |
|
|
|
|
100% |
++++ |
++++ |
|
|
|
|
+ expression forms gel
Above-mentioned experiment shows, can form gelinite behind the goods adding vegetable oil of the present invention under the condition of simulation hydrochloric acid in gastric juice, reduces free aliphatic acid, therefore can suppress to delay interior absorption of body of aliphatic acid.
4. volunteer's eating effect experiment
Adopt the goods of embodiment 2 to be used for this experiment.
Select the age in 22-45 year, body weight has low alcohol consumption custom person at ordinary times at the healthy male of 55-75 kilogram, is divided into 4 groups at random.The 1st group: in 1-3 minute, drink 56% strong, colourless liquor distilled from sorghum 100ml, drink common fruit juice simultaneously; The 2nd group: in 1-3 minute, drink 56% strong, colourless liquor distilled from sorghum 100ml, drink 200ml goods of the present invention simultaneously; The 3rd group: in 1-3 minute, drink 13.5% claret 200ml, drink common fruit juice simultaneously; The 4th group: in 1-3 minute, drink 13.5% claret 200ml, drink 200ml goods of the present invention simultaneously.Before drinking and drink finish in back 1 hour every after 5 minutes, 1 hour every measured in 10 minutes exhale in alcohol content, till can not measuring.The calculating mean value as a result of each time point determining.
The result is as follows: experimental data shows at the strong, colourless liquor distilled from sorghum 100ml that drinks 56%, drink in the absence of goods of the present invention, the back breath of drinking contained very high alcohol concentration (Fig. 1) at 6 hours, and drink simultaneously under the situation of goods of the present invention, the content of alcohol is not than drinking obvious reduction in the breath, and the alcohol holdup time in vivo obviously shortens (Fig. 2).Drinking the 200ml red wine, drink in the absence of sample, breath can be measured alcohol content in 120 minutes, be in the state of drinking (Fig. 3), and drink at the same time under the situation of this sample, breath was not measured alcohol content in 15 minutes-150 minutes that observe, be in the non-state of drinking (Fig. 4), and the alcohol of the breath in 15 minutes is the cause that remains in alcohol in the oral cavity after drinking.Therefore, the present invention can obviously suppress to delay alcohol and absorb, and reduces BAC, and shortening alcohol is the holdup time in vivo.
The result that goods of the present invention are used in vitro test shows, these goods and liquor, red wine and COF mix after the back becomes colloid, the free molecule that can absorb in the food is reduced, so inhibition delay the absorption of COF.In vivo studies shows that the present invention can obviously suppress alcohol absorption in liquor and the red wine, reduces BAC, and shortening alcohol is the holdup time in vivo.These goods can be used to pre-preventing drunkenness of the crowd of drinking and treatment drunk person.