CN101479325B - 可聚合的硅氧烷-季胺共聚物 - Google Patents
可聚合的硅氧烷-季胺共聚物 Download PDFInfo
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- CN101479325B CN101479325B CN200780023604.6A CN200780023604A CN101479325B CN 101479325 B CN101479325 B CN 101479325B CN 200780023604 A CN200780023604 A CN 200780023604A CN 101479325 B CN101479325 B CN 101479325B
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- BNBQRQQYDMDJAH-UHFFFAOYSA-N benzodioxan Chemical compound C1=CC=C2OCCOC2=C1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 description 1
- 125000004618 benzofuryl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 description 1
- 125000004619 benzopyranyl group Chemical group O1C(C=CC2=C1C=CC=C2)* 0.000 description 1
- 125000001164 benzothiazolyl group Chemical group S1C(=NC2=C1C=CC=C2)* 0.000 description 1
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- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
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- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 1
- 125000005879 dioxolanyl group Chemical group 0.000 description 1
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 description 1
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- ZHPNWZCWUUJAJC-UHFFFAOYSA-N fluorosilicon Chemical compound [Si]F ZHPNWZCWUUJAJC-UHFFFAOYSA-N 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 125000002541 furyl group Chemical group 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
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- 229910052736 halogen Inorganic materials 0.000 description 1
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- 125000004475 heteroaralkyl group Chemical class 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 150000002430 hydrocarbons Chemical group 0.000 description 1
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- 125000002636 imidazolinyl group Chemical group 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
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- 125000003454 indenyl group Chemical group C1(C=CC2=CC=CC=C12)* 0.000 description 1
- 125000003387 indolinyl group Chemical group N1(CCC2=CC=CC=C12)* 0.000 description 1
- HOBCFUWDNJPFHB-UHFFFAOYSA-N indolizine Chemical compound C1=CC=CN2C=CC=C21 HOBCFUWDNJPFHB-UHFFFAOYSA-N 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- LRDFRRGEGBBSRN-UHFFFAOYSA-N isobutyronitrile Chemical compound CC(C)C#N LRDFRRGEGBBSRN-UHFFFAOYSA-N 0.000 description 1
- HEBMCVBCEDMUOF-UHFFFAOYSA-N isochromane Chemical compound C1=CC=C2COCCC2=C1 HEBMCVBCEDMUOF-UHFFFAOYSA-N 0.000 description 1
- 125000004594 isoindolinyl group Chemical group C1(NCC2=CC=CC=C12)* 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
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- 229930182817 methionine Natural products 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 125000002757 morpholinyl group Chemical group 0.000 description 1
- YPHQUSNPXDGUHL-UHFFFAOYSA-N n-methylprop-2-enamide Chemical group CNC(=O)C=C YPHQUSNPXDGUHL-UHFFFAOYSA-N 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
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- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 1
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- 125000001644 phenoxazinyl group Chemical group C1(=CC=CC=2OC3=CC=CC=C3NC12)* 0.000 description 1
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- 150000003016 phosphoric acids Chemical class 0.000 description 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 description 1
- 125000004592 phthalazinyl group Chemical group C1(=NN=CC2=CC=CC=C12)* 0.000 description 1
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- VVWRJUBEIPHGQF-UHFFFAOYSA-N propan-2-yl n-propan-2-yloxycarbonyliminocarbamate Chemical compound CC(C)OC(=O)N=NC(=O)OC(C)C VVWRJUBEIPHGQF-UHFFFAOYSA-N 0.000 description 1
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- YOIAWAIKYVEKMF-UHFFFAOYSA-N trifluoromethanesulfonic acid Chemical compound OS(=O)(=O)C(F)(F)F.OS(=O)(=O)C(F)(F)F YOIAWAIKYVEKMF-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/452—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/38—Polysiloxanes modified by chemical after-treatment
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Eyeglasses (AREA)
- Materials For Medical Uses (AREA)
- Silicon Polymers (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/479,608 US7468397B2 (en) | 2006-06-30 | 2006-06-30 | Polymerizable siloxane-quaternary amine copolymers |
| US11/479,608 | 2006-06-30 | ||
| PCT/US2007/070509 WO2008005644A1 (en) | 2006-06-30 | 2007-06-06 | Polymerizable siloxane-quaternary amine copolymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101479325A CN101479325A (zh) | 2009-07-08 |
| CN101479325B true CN101479325B (zh) | 2013-06-26 |
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| CN200780023604.6A Expired - Fee Related CN101479325B (zh) | 2006-06-30 | 2007-06-06 | 可聚合的硅氧烷-季胺共聚物 |
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| Country | Link |
|---|---|
| US (2) | US7468397B2 (enExample) |
| EP (2) | EP2404951B1 (enExample) |
| JP (1) | JP5519277B2 (enExample) |
| CN (1) | CN101479325B (enExample) |
| AT (1) | ATE555150T1 (enExample) |
| BR (1) | BRPI0712367A2 (enExample) |
| CA (1) | CA2652075A1 (enExample) |
| ES (2) | ES2428273T3 (enExample) |
| WO (1) | WO2008005644A1 (enExample) |
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| US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US7828728B2 (en) * | 2003-07-25 | 2010-11-09 | Dexcom, Inc. | Analyte sensor |
| JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8277713B2 (en) * | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
| US20070045902A1 (en) | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor |
| US9414777B2 (en) | 2004-07-13 | 2016-08-16 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8744546B2 (en) * | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
| JP2008543602A (ja) * | 2005-05-09 | 2008-12-04 | エヌディーエスユー リサーチ ファウンデーション | ポリアミン架橋されたポリシロキサンを含有する防汚物質 |
| US7759408B2 (en) * | 2005-12-21 | 2010-07-20 | Bausch & Lomb Incorporated | Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups |
| US7825273B2 (en) * | 2006-01-06 | 2010-11-02 | Bausch & Lomb Incorporated | Process for making cationic hydrophilic siloxanyl monomers |
| US8828420B2 (en) * | 2006-01-06 | 2014-09-09 | Bausch & Lomb Incorporated | Siloxane prepolymer containing pendant cationic and polymerizable groups |
| US7960447B2 (en) | 2006-04-13 | 2011-06-14 | Bausch & Lomb Incorporated | Cationic end-capped siloxane prepolymer for reduced cross-link density |
| US8105623B2 (en) * | 2006-06-30 | 2012-01-31 | Bausch & Lomb Incorporated | Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups |
| US7781558B2 (en) * | 2006-09-27 | 2010-08-24 | Bausch & Lomb Incorporated | Hydrophilic siloxanyl monomers with pendant polymerizable groups |
| US7579021B2 (en) * | 2006-09-27 | 2009-08-25 | Bausch & Lomb Incorporated | Drug delivery systems based on degradable cationic siloxanyl macromonomers |
| US8372384B2 (en) * | 2007-01-08 | 2013-02-12 | Ndsu Research Foundation | Quaternary ammonium functionalized cross-linked polyalkylsiloxanes with anti-fouling activity |
| US7951897B2 (en) | 2007-01-26 | 2011-05-31 | Bausch & Lomb Incorporated | Synthesis of cationic siloxane prepolymers |
| US8709394B2 (en) * | 2007-09-28 | 2014-04-29 | Ndsu Research Foundation | Antimicrobial polysiloxane materials containing metal species |
| US20100004202A1 (en) * | 2008-02-15 | 2010-01-07 | Ndsu Research Foundation | Quaternary ammonium-functionalized-POSS compounds |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| EP3387993A3 (en) * | 2008-03-28 | 2018-11-14 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8093352B2 (en) * | 2008-08-05 | 2012-01-10 | Alcon Research, Ltd. | Polyalkylene oxide polyquaternary ammonium biocides |
| US8560039B2 (en) | 2008-09-19 | 2013-10-15 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
| US20110212994A1 (en) | 2009-06-26 | 2011-09-01 | Brian Clem | Small Molecule Choline Kinase Inhibitors, Screening Assays, and Methods for Safe and Effective Treatment of Neoplastic Disorders |
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| WO2012047969A1 (en) | 2010-10-06 | 2012-04-12 | Novartis Ag | Water-processable silicone-containing prepolymers and uses thereof |
| WO2012047961A1 (en) | 2010-10-06 | 2012-04-12 | Novartis Ag | Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups |
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| US9486311B2 (en) | 2013-02-14 | 2016-11-08 | Shifamed Holdings, Llc | Hydrophilic AIOL with bonding |
| AU2014236688B2 (en) | 2013-03-21 | 2019-07-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| US10195018B2 (en) | 2013-03-21 | 2019-02-05 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| AU2015306613B2 (en) | 2014-08-26 | 2018-01-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| US9976974B2 (en) * | 2015-01-27 | 2018-05-22 | University Of Utah Research Foundation | Osmolarity-responsive hydrogel sensors and method of use |
| CN108472129B (zh) | 2015-11-18 | 2021-09-24 | 施菲姆德控股有限责任公司 | 组合的调节性人工晶状体 |
| US11141263B2 (en) | 2015-11-18 | 2021-10-12 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| US10350056B2 (en) | 2016-12-23 | 2019-07-16 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lenses and methods for making and using same |
| JP6954679B2 (ja) | 2016-12-23 | 2021-10-27 | シファメド・ホールディングス・エルエルシー | マルチピース調節式眼内レンズ、及び同を作成し、使用するための方法 |
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| JP7082822B2 (ja) | 2017-06-07 | 2022-06-09 | シファメド・ホールディングス・エルエルシー | 調整可能な屈折力の眼内レンズ |
| US20250313670A1 (en) * | 2022-06-02 | 2025-10-09 | Momentive Performance Materials Inc. | Polysiloxane polymer composition and the preparation method thereof |
| JP2025009288A (ja) * | 2023-07-07 | 2025-01-20 | 信越化学工業株式会社 | 分子鎖中に第３級アミノ基または第４級アンモニウムカチオン部位を有する両末端（メタ）アクリル変性シリコーンマクロマーおよびその製造方法 |
| WO2025215096A1 (en) * | 2024-04-11 | 2025-10-16 | Bausch + Lomb Ireland Limited | Silicone contact lens-forming prepolymer and silicone contact lens formed therefrom |
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- 2007-06-06 CN CN200780023604.6A patent/CN101479325B/zh not_active Expired - Fee Related
- 2007-06-06 EP EP11177006.1A patent/EP2404951B1/en not_active Not-in-force
- 2007-06-06 CA CA002652075A patent/CA2652075A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| US20090143556A1 (en) | 2009-06-04 |
| ATE555150T1 (de) | 2012-05-15 |
| WO2008005644A1 (en) | 2008-01-10 |
| US20080001318A1 (en) | 2008-01-03 |
| ES2382863T3 (es) | 2012-06-14 |
| CA2652075A1 (en) | 2008-01-10 |
| US7468397B2 (en) | 2008-12-23 |
| BRPI0712367A2 (pt) | 2012-06-05 |
| EP2035486B1 (en) | 2012-04-25 |
| HK1164348A1 (en) | 2012-09-21 |
| JP5519277B2 (ja) | 2014-06-11 |
| EP2035486A1 (en) | 2009-03-18 |
| HK1127621A1 (en) | 2009-10-02 |
| EP2404951B1 (en) | 2013-09-11 |
| EP2404951A1 (en) | 2012-01-11 |
| ES2428273T3 (es) | 2013-11-06 |
| CN101479325A (zh) | 2009-07-08 |
| JP2009542855A (ja) | 2009-12-03 |
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