CN101468237A - Stimulator for implantation in vivo - Google Patents

Stimulator for implantation in vivo Download PDF

Info

Publication number
CN101468237A
CN101468237A CNA2008100943522A CN200810094352A CN101468237A CN 101468237 A CN101468237 A CN 101468237A CN A2008100943522 A CNA2008100943522 A CN A2008100943522A CN 200810094352 A CN200810094352 A CN 200810094352A CN 101468237 A CN101468237 A CN 101468237A
Authority
CN
China
Prior art keywords
stimulator
substrate
implantation
circuit
components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CNA2008100943522A
Other languages
Chinese (zh)
Other versions
CN101468237B (en
Inventor
吉为民
徐海东
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Acoustics CAS
Original Assignee
Institute of Acoustics CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Acoustics CAS filed Critical Institute of Acoustics CAS
Priority to CN2008100943522A priority Critical patent/CN101468237B/en
Publication of CN101468237A publication Critical patent/CN101468237A/en
Application granted granted Critical
Publication of CN101468237B publication Critical patent/CN101468237B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Abstract

The present invention relates to an in-vivo implantation stimulator which comprises a stimulation electronic system composed of electronic components and an integrated circuit. The invention is characterized in that a flexible bendable folding film which has a thickness of 0.1mm-0.2mm is adopted as a substrate. The substrate is printed with a metallic circuit as a current substrate film. The circuit and components are pressed and welded on the inner layer and outer layer of substrate film. The circuit substrate film has a cylinder shape. The electronic components are arranged between two pie-shaped substrates crossly. The two pie-shaped substrates have a cylinder shape after combination. The folding surface of whole assembly is wholly coated with a water-proof and moisture-proof coating after the electronic components are installed on the substrate. The stimulation electronic system and the substrate are contained in the titanium casing which is made of pure titanium. The titanium casing is wholly covered with medical adhesive. The invention adopts a novel material and a novel structure for greatly reducing the thickness of stimulator, arranging and installing the components more flexibly, and facilitating implantation into human body.

Description

Stimulator for implantation in vivo
Technical field
The present invention relates to the stimulator in the nerve stimulation device of therapeutic medical implant into body, particularly a kind of stimulator for implantation in vivo.
Background technology
At present, human body stimulator (body is implanted into system) adopts electronic devices and components and integrated circuit to form a complete stimulation electronic system, all adopts pottery or hard non-metallic material as the circuit substrate that components and parts are installed usually.The human body stimulator for implantation is made up of integrated circuit and electronic component, it is included in the housing of titanium TA1 or ceramic material, form independently complete body stimulating system, an end that connects the metal electrode bundle on the substrate, the other end of electrode contacts with feature organization in the body or links to each other, like this, and its inner extraction electrode, export neuroactive electric excitation signal or electric current, reach the effect of treatment and restore funcitons.
Because the stimulator in the nerve stimulation device of all kinds of medical treatment of implant into body, be embedded in the skeleton or cavity tissue at each position of human body, consider that from the anatomy of human body the stimulator installation position is limited, and even be specific, so the volume (physical dimensions such as thickness, diameter) of the stimulator that is used for human body there is special requirement.
But,, all be to adopt epoxy resin board, two kinds of base materials of ceramic substrate basically as interplantation stimulator circuitry substrate from the domestic and international content of reporting.Like this, because the reason of material, the thickness of substrate and the density of cloth spare are all not ideal enough.And, showing that from the human dissection principle implant (stimulator) volume, one-tenth-value thickness 1/10 are big more, difficulty can take place in the position of its placement during operation, can produce danger when serious.
Summary of the invention
The objective of the invention is to, for overcoming above-mentioned deficiency of the prior art, thereby provide a kind of ultrathin structure stimulator for implantation in vivo.
For achieving the above object, stimulator for implantation in vivo of the present invention, comprise: the stimulation electronic system of forming by electronic devices and components and integrated circuit, it is characterized in that, adopting thickness is that 0.1 millimeter~0.2 millimeter flexible folding film is as substrate, print metallic circuit on the described substrate as the circuit basement membrane, circuit and components and parts coining are welded on the ectonexine of basement membrane.
As a kind of improvement of the present invention, described substrate employing high-low temperature resistant, the engineering plastics thin film that withstand voltage properties is good.
As another improvement of the present invention, it is conjuncted that described circuit basement membrane is circle, and described electronic devices and components arranged crosswise is in the centres of two circle basivalvulas, and two round basivalvulas are rounded body after altogether.
As another improvement of the present invention, after described electronic devices and components were installed on the substrate, amounting on the face of whole assembly wholely applied waterproof and dampproof coating, and row is amounted to again.
As another kind of improvement the of the present invention, described stimulation electronic system and chip holding thereof are in the titanium shell that pure titanium is made.Adopt titanium (TA1) as containing material (stimulator shell), reach the ideal human-body biological compatibility.Further, the outer whole medical glue that covers of described titanium shell is to realize curing, buffer protection.
The invention has the advantages that the present invention adopts a kind of new material and structure, it is thin that the thickness of stimulator is greatly changed, and components and parts are arranged and installed more flexibly, help human body and implant.
Show that from the human dissection principle implant (stimulator) volume is the smaller the better, Bao Yueyou more, its one-tenth-value thickness 1/10 is particularly important, otherwise during operation, difficulty can take place in the position of its placement, can produce danger when serious.The structure of embedded nerve stimulator provided by the present invention has solved above problem, can accomplish the little ultrathin structure of its stimulator volume.
Description of drawings
Fig. 1 is the sketch map after the substrate of stimulator for implantation in vivo of the present invention launches.
Fig. 2 is the sketch map after the amounting to of stimulator for implantation in vivo of the present invention.
Fig. 3 is the cut-away view after the stimulator for implantation in vivo of Fig. 2 is amounted to.
The specific embodiment
Further describe stimulator for implantation in vivo of the present invention below in conjunction with accompanying drawing.
As Fig. 1~shown in Figure 3, the present invention adopts the substrate (high-low temperature resistant, the engineering plastics thin film that withstand voltage properties is good) of flexible folding film, print metallic circuit above, thickness adopts 0.1 millimeter to 0.2 millimeter (mm) thick, as the circuit basement membrane, circuit and components and parts coining are welded on the ectonexine of basement membrane.It is conjuncted that its basement membrane is designed to a circle, as shown in Figure 1, just becomes a rounded body altogether, as shown in Figure 2.Its electronic devices and components are placed in the centre of two circle basivalvulas, but arranged crosswise, and thickness reduces not to the utmost, and has saved its space greatly, and the volume of interplantation stimulator, thickness are greatly improved, and has reached extra-thin structure.

Claims (6)

1, a kind of stimulator for implantation in vivo, comprise: the stimulation electronic system of forming by electronic devices and components and integrated circuit, it is characterized in that, adopting thickness is that 0.1 millimeter~0.2 millimeter flexible folding film is as substrate, print metallic circuit on the described substrate as the circuit basement membrane, circuit and components and parts coining are welded on the ectonexine of basement membrane.
2, stimulator for implantation in vivo according to claim 1 is characterized in that, described substrate employing high-low temperature resistant, the engineering plastics thin film that withstand voltage properties is good.
3, stimulator for implantation in vivo according to claim 1 is characterized in that, it is conjuncted that described circuit basement membrane is circle, and described electronic devices and components arranged crosswise is in the centres of two circle basivalvulas, and two round basivalvulas are rounded body after altogether.
4, stimulator for implantation in vivo according to claim 1 is characterized in that, after described electronic devices and components are installed on the substrate, whole assembly amount on the face the whole waterproof and dampproof coating that applies.
According to the described stimulator for implantation in vivo of claim 1~4, it is characterized in that 5, described stimulation electronic system and chip holding thereof are in the titanium shell that pure titanium is made.
6, stimulator for implantation in vivo according to claim 5 is characterized in that, the outer whole medical glue that covers of described titanium shell.
CN2008100943522A 2007-12-26 2008-04-29 Stimulator for implantation in vivo Expired - Fee Related CN101468237B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2008100943522A CN101468237B (en) 2007-12-26 2008-04-29 Stimulator for implantation in vivo

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200710303834.X 2007-12-26
CN200710303834 2007-12-26
CN2008100943522A CN101468237B (en) 2007-12-26 2008-04-29 Stimulator for implantation in vivo

Publications (2)

Publication Number Publication Date
CN101468237A true CN101468237A (en) 2009-07-01
CN101468237B CN101468237B (en) 2012-10-17

Family

ID=40826196

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008100943522A Expired - Fee Related CN101468237B (en) 2007-12-26 2008-04-29 Stimulator for implantation in vivo

Country Status (1)

Country Link
CN (1) CN101468237B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102939115A (en) * 2010-03-26 2013-02-20 伊维博有限公司 Medical device
CN108325082A (en) * 2010-10-26 2018-07-27 美敦力公司 Chip scale package including power supply

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN86205046U (en) * 1986-07-28 1987-02-18 上海医用电子仪器厂 Suspension type thin film one-through use electric pole
CN2462970Y (en) * 2000-12-07 2001-12-05 陕西秦明医学仪器股份有限公司 Pulse generator for cardiac pacemaker
CN2910251Y (en) * 2006-03-10 2007-06-13 清华大学 Sealing means for implanting electrical stimulator

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102939115A (en) * 2010-03-26 2013-02-20 伊维博有限公司 Medical device
CN108325082A (en) * 2010-10-26 2018-07-27 美敦力公司 Chip scale package including power supply

Also Published As

Publication number Publication date
CN101468237B (en) 2012-10-17

Similar Documents

Publication Publication Date Title
US11690548B2 (en) Method for implanting an implantable device in body tissue
Stauss et al. Biocompatible batteries—materials and chemistry, fabrication, applications, and future prospects
US8175710B2 (en) Stimulator system with electrode array and the method of making the same
CN110621227B (en) Sensor system and method for producing the same
US3735766A (en) Optional unipolar-bipolar body organ stimulator
US8634895B2 (en) Biomedical surface electrode
US20160220827A1 (en) Construction for an Implantable Medical Device Having a Battery Affixed to the Case
WO2011075480A3 (en) Cochlear electrode array
CN101541237A (en) Ingestible electronic capsule and in vivo drug delivery or diagnostic system
JP2005521455A5 (en)
WO2004073483A3 (en) Surface electrode for electrical stimulation of tissue
WO2009062114A3 (en) Cochlear stimulation device comprising a flexible electrode array
CN109999343B (en) Electronic packaging body of implantable device and retina stimulator
WO2007103262A3 (en) Implanted cardiac device for defibrillation
CN101468237B (en) Stimulator for implantation in vivo
Yu et al. Emerging Design Strategies Toward Developing Next‐Generation Implantable Batteries and Supercapacitors
AU2017361863C1 (en) Implantable electrical contact arrangement
Ordonez et al. A 232-channel retinal vision prosthesis with a miniaturized hermetic package
EP1886628A3 (en) Antenna and body implant
RU2010114303A (en) IMPLANTED DEVICE
CN110167614A (en) Micro- delivery apparatus
CN101658418A (en) Flexible disposable medical electrode
CN211912457U (en) Flexible patch electrode for spinal cord recording or stimulation
CN114585413A (en) Hybrid flexible-rigid electrical interconnect system
US20070134974A1 (en) Housing for a medical implant

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20121017

Termination date: 20150429

EXPY Termination of patent right or utility model