CN101468237B - Stimulator for implantation in vivo - Google Patents

Stimulator for implantation in vivo Download PDF

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Publication number
CN101468237B
CN101468237B CN2008100943522A CN200810094352A CN101468237B CN 101468237 B CN101468237 B CN 101468237B CN 2008100943522 A CN2008100943522 A CN 2008100943522A CN 200810094352 A CN200810094352 A CN 200810094352A CN 101468237 B CN101468237 B CN 101468237B
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CN
China
Prior art keywords
substrate
stimulator
circuit
implantation
components
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Expired - Fee Related
Application number
CN2008100943522A
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Chinese (zh)
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CN101468237A (en
Inventor
吉为民
徐海东
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Institute of Acoustics CAS
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Institute of Acoustics CAS
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Priority to CN2008100943522A priority Critical patent/CN101468237B/en
Publication of CN101468237A publication Critical patent/CN101468237A/en
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Publication of CN101468237B publication Critical patent/CN101468237B/en
Expired - Fee Related legal-status Critical Current
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Abstract

The present invention relates to an in-vivo implantation stimulator which comprises a stimulation electronic system composed of electronic components and an integrated circuit. The invention is characterized in that a flexible bendable folding film which has a thickness of 0.1mm-0.2mm is adopted as a substrate. The substrate is printed with a metallic circuit as a current substrate film. The circuit and components are pressed and welded on the inner layer and outer layer of substrate film. The circuit substrate film has a cylinder shape. The electronic components are arranged between two pie-shaped substrates crossly. The two pie-shaped substrates have a cylinder shape after combination. The folding surface of whole assembly is wholly coated with a water-proof and moisture-proof coating after the electronic components are installed on the substrate. The stimulation electronic system and the substrate are contained in the titanium casing which is made of pure titanium. The titanium casing is wholly covered with medical adhesive. The invention adopts a novel material and a novel structure for greatly reducing the thickness of stimulator, arranging and installing the components more flexibly, and facilitating implantation into human body.

Description

Stimulator for implantation in vivo
Technical field
The present invention relates to the stimulator in the nerve stimulation device of therapeutic medical implant into body, particularly a kind of stimulator for implantation in vivo.
Background technology
At present, human body stimulator (body is implanted into system) adopts electronic devices and components and integrated circuit to form a complete stimulation electronic system, all adopts pottery or the hard non-metallic material circuit substrate as the installation components and parts usually.The human body stimulator for implantation is made up of integrated circuit and electronic component, and it is included in the housing of titanium TA1 or ceramic material, forms independently complete body stimulating system; An end that connects the metal electrode bundle on the substrate; Feature organization contacts or links to each other in the other end of electrode and the body, like this, and its inner extraction electrode; Export neuroactive electric excitation signal or electric current, reach the effect of treatment and restore funcitons.
Because the stimulator in the nerve stimulation device of all kinds of medical treatment of implant into body; Be embedded in the skeleton or cavity tissue at each position of human body; Consider that from the anatomy of human body the stimulator installation position is limited; And even be specific, so the volume (physical dimensions such as thickness, diameter) of the stimulator that is used for human body there is special requirement.
But,, all be to adopt epoxy resin board, two kinds of base materials of ceramic substrate basically as interplantation stimulator circuitry substrate from the domestic and international content of reporting.Like this, because the reason of material, the thickness of substrate and the density of cloth spare are all not ideal enough.And, showing that from the human dissection principle implant (stimulator) volume, one-tenth-value thickness 1/10 are big more, difficulty can take place in the position of its placement during operation, can produce danger when serious.
Summary of the invention
The objective of the invention is to, for overcoming above-mentioned deficiency of the prior art, thereby a kind of ultrathin structure stimulator for implantation in vivo is provided.
For realizing above-mentioned purpose; Stimulator for implantation in vivo of the present invention; Comprise: the stimulation electronic system by electronic devices and components and integrated circuit are formed is characterized in that adopting thickness is that 0.1 millimeter~0.2 millimeter flexible folding film is as substrate; Print metallic circuit on the said substrate and form the circuit basement membrane, integrated circuit and electronic devices and components coining are welded on the ectonexine of circuit basement membrane; Said substrate employing high-low temperature resistant, the engineering plastics thin film that withstand voltage properties is good; Said circuit basement membrane is the conjuncted circuit basement membrane of circle that two lobe circular substrates are linked to be, described integrated circuit and electronic devices and components arranged crosswise two lobe circular substrates amount to that the back forms the space among, two lobe circular substrates are rounded body after altogether.
As another improvement of the present invention, after said electronic devices and components are installed on the substrate, substrate and on amounting on the face of stimulation electronic system wholely applied waterproof and dampproof coating, row is amounted to again.
As another kind of improvement the of the present invention, said stimulation electronic system and chip holding thereof are in the titanium shell that pure titanium is processed.Adopt titanium (TA1) as containing material (stimulator shell), reach the ideal human-body biological compatibility.Further, the outer whole medical glue that covers of said titanium shell is to realize curing, buffer protection.
The invention has the advantages that the present invention adopts a kind of new material and structure, it is thin that the thickness of stimulator is greatly changed, and components and parts are arranged and installed more flexibly, help human body and implant.
Show from the human dissection principle, more little good more, the Bao Yueyou more of implant (stimulator) volume, its one-tenth-value thickness 1/10 is particularly important, otherwise during operation, difficulty can take place in the position of its placement, can produce danger when serious.The structure of embedded nerve stimulator provided by the present invention has solved above problem, can accomplish the little ultrathin structure of its stimulator volume.
Description of drawings
Fig. 1 is the sketch map after the substrate of stimulator for implantation in vivo of the present invention launches.
Fig. 2 is the sketch map after the amounting to of stimulator for implantation in vivo of the present invention.
Fig. 3 is the cut-away view after the stimulator for implantation in vivo of Fig. 2 is amounted to.
The specific embodiment
Below in conjunction with accompanying drawing further explain stimulator for implantation in vivo of the present invention.
Like Fig. 1~shown in Figure 3; The present invention adopts the substrate (high-low temperature resistant, the engineering plastics thin film that withstand voltage properties is good) of flexible folding film; Print metallic circuit above; Thickness adopts 0.1 millimeter to 0.2 millimeter (mm) thick, and as the circuit basement membrane, circuit and components and parts coining are welded on the ectonexine of basement membrane.It is conjuncted, as shown in Figure 1 that its basement membrane is designed to a circle, just becomes a rounded body altogether, as shown in Figure 2.Its electronic devices and components are placed in the centre of two circle basivalvulas, but arranged crosswise, and not only thickness reduces, and has practiced thrift its space greatly, and the volume of interplantation stimulator, thickness are greatly improved, and has reached extra-thin structure.

Claims (4)

1. stimulator for implantation in vivo; Comprise: the stimulation electronic system of forming by electronic devices and components and integrated circuit; It is characterized in that; Adopt thickness be 0.1 millimeter~0.2 millimeter flexible folding film as substrate, print metallic circuit on the said substrate and form the circuit basement membrane, integrated circuit and electronic devices and components coining are welded on the ectonexine of circuit basement membrane;
Said substrate employing high-low temperature resistant, the engineering plastics thin film that withstand voltage properties is good;
Said circuit basement membrane is the conjuncted circuit basement membrane of circle that two lobe circular substrates are linked to be, and described integrated circuit and electronic devices and components arranged crosswise are among two lobe circular substrates are amounted to the space that the back forms, and two lobe circular substrates are rounded body after altogether.
2. stimulator for implantation in vivo according to claim 1 is characterized in that, after described integrated circuit and electronic devices and components are installed on the substrate, substrate and on the stimulation electronic system amount on the face the whole waterproof and dampproof coating that applies.
3. stimulator for implantation in vivo according to claim 1 and 2 is characterized in that, said stimulation electronic system and chip holding thereof are in the titanium shell that pure titanium is processed.
4. stimulator for implantation in vivo according to claim 3 is characterized in that, the outer whole medical glue that covers of said titanium shell.
CN2008100943522A 2007-12-26 2008-04-29 Stimulator for implantation in vivo Expired - Fee Related CN101468237B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2008100943522A CN101468237B (en) 2007-12-26 2008-04-29 Stimulator for implantation in vivo

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200710303834.X 2007-12-26
CN200710303834 2007-12-26
CN2008100943522A CN101468237B (en) 2007-12-26 2008-04-29 Stimulator for implantation in vivo

Publications (2)

Publication Number Publication Date
CN101468237A CN101468237A (en) 2009-07-01
CN101468237B true CN101468237B (en) 2012-10-17

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CN2008100943522A Expired - Fee Related CN101468237B (en) 2007-12-26 2008-04-29 Stimulator for implantation in vivo

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201005122D0 (en) * 2010-03-26 2010-05-12 Invibio Ltd Medical device
US8666505B2 (en) * 2010-10-26 2014-03-04 Medtronic, Inc. Wafer-scale package including power source

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN86205046U (en) * 1986-07-28 1987-02-18 上海医用电子仪器厂 Suspension type thin film one-through use electric pole
CN2462970Y (en) * 2000-12-07 2001-12-05 陕西秦明医学仪器股份有限公司 Pulse generator for cardiac pacemaker
CN2910251Y (en) * 2006-03-10 2007-06-13 清华大学 Sealing means for implanting electrical stimulator

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN86205046U (en) * 1986-07-28 1987-02-18 上海医用电子仪器厂 Suspension type thin film one-through use electric pole
CN2462970Y (en) * 2000-12-07 2001-12-05 陕西秦明医学仪器股份有限公司 Pulse generator for cardiac pacemaker
CN2910251Y (en) * 2006-03-10 2007-06-13 清华大学 Sealing means for implanting electrical stimulator

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