CN101460504A - 作为体内成像化合物的三环氧氮杂类 - Google Patents

作为体内成像化合物的三环氧氮杂类 Download PDF

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Publication number
CN101460504A
CN101460504A CNA2007800202961A CN200780020296A CN101460504A CN 101460504 A CN101460504 A CN 101460504A CN A2007800202961 A CNA2007800202961 A CN A2007800202961A CN 200780020296 A CN200780020296 A CN 200780020296A CN 101460504 A CN101460504 A CN 101460504A
Authority
CN
China
Prior art keywords
compound
imaging
hydrogen
alkyl
pbr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800202961A
Other languages
English (en)
Chinese (zh)
Inventor
E·阿斯塔德
E·G·罗宾斯
Y·赵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hammersmith Imanet Ltd
Original Assignee
Hammersmith Imanet Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hammersmith Imanet Ltd filed Critical Hammersmith Imanet Ltd
Publication of CN101460504A publication Critical patent/CN101460504A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CNA2007800202961A 2006-06-02 2007-05-31 作为体内成像化合物的三环氧氮杂类 Pending CN101460504A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0610866.6A GB0610866D0 (en) 2006-06-02 2006-06-02 Novel in vivo imaging compounds
GB0610866.6 2006-06-02

Publications (1)

Publication Number Publication Date
CN101460504A true CN101460504A (zh) 2009-06-17

Family

ID=36694794

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800202961A Pending CN101460504A (zh) 2006-06-02 2007-05-31 作为体内成像化合物的三环氧氮杂类

Country Status (6)

Country Link
US (1) US20090317328A1 (enExample)
EP (1) EP2024373A1 (enExample)
JP (1) JP2009538894A (enExample)
CN (1) CN101460504A (enExample)
GB (1) GB0610866D0 (enExample)
WO (1) WO2007141491A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104744491A (zh) * 2009-09-28 2015-07-01 霍夫曼-拉罗奇有限公司 苯并氧杂氮杂*pi3k抑制剂化合物和使用方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5324122B2 (ja) * 2008-04-08 2013-10-23 関東電化工業株式会社 含フッ素アシル化アミン及びその製造方法
WO2010093001A1 (ja) * 2009-02-13 2010-08-19 国立大学法人大阪大学 アルツハイマー病の診断方法および診断薬
GB0908711D0 (en) * 2009-05-20 2009-07-01 Isis Innovation Preparation of labelled compounds
WO2011006922A1 (en) * 2009-07-14 2011-01-20 Sanofi-Aventis Deutschland Gmbh Medicament container with a flexible inner layer and a rigid outer layer
US20150190534A1 (en) * 2014-01-09 2015-07-09 University Of Bern Compounds for use as positron emission imaging agents
PE20211775A1 (es) 2015-07-02 2021-09-08 Hoffmann La Roche Compuestos de benzoxacepina oxazolidinona y metodos de uso

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994258A (en) * 1990-03-05 1991-02-19 Merck & Co., Inc. Gamma emitting, CCK-A antagonists for pancreatic imaging
JP2586411B2 (ja) * 1995-03-03 1997-02-26 住友化学工業株式会社 放射性ベンゾジアゼピン誘導体およびその製造法
US5998624A (en) * 1997-05-07 1999-12-07 Emory University Haloisoquinoline carboxamide
AUPP278498A0 (en) * 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
AU3843899A (en) * 1998-05-06 1999-11-23 Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin, The Apoptosis-inducing compounds
IE20000120A1 (en) * 2000-02-11 2003-03-05 Trinity College Dublin Apoptosis - inducing compounds
GB0523506D0 (en) * 2005-11-18 2005-12-28 Hammersmith Imanet Ltd Novel in vivo imaging compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104744491A (zh) * 2009-09-28 2015-07-01 霍夫曼-拉罗奇有限公司 苯并氧杂氮杂*pi3k抑制剂化合物和使用方法
CN104744491B (zh) * 2009-09-28 2017-07-11 霍夫曼-拉罗奇有限公司 苯并氧杂氮杂*pi3k抑制剂化合物和使用方法

Also Published As

Publication number Publication date
JP2009538894A (ja) 2009-11-12
GB0610866D0 (en) 2006-07-12
WO2007141491A1 (en) 2007-12-13
US20090317328A1 (en) 2009-12-24
EP2024373A1 (en) 2009-02-18

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20090617