CN101455574A - Imaging system and method - Google Patents
Imaging system and method Download PDFInfo
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- CN101455574A CN101455574A CNA2009103001151A CN200910300115A CN101455574A CN 101455574 A CN101455574 A CN 101455574A CN A2009103001151 A CNA2009103001151 A CN A2009103001151A CN 200910300115 A CN200910300115 A CN 200910300115A CN 101455574 A CN101455574 A CN 101455574A
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Abstract
The present invention discloses an imaging system which comprises the following components: a sample carrying table which is placed with a sample to be imaged; a beam source part which radiates beam; a beam detecting collecting part which receives a beam image; a rotation control part which has two ends respectively fixedly connected with the beam source part and the beam detecting collecting part and drives the beam source part and beam collecting part to rotate; and a computer which transmits control instruction to the beam source part, the rotation control part and the detecting collecting part and receives the image received by the beam detecting collecting part for imaging processing. The invention also correspondingly provides an imaging method. According to the imaging method, an expected imaging requirement is input. The related parameters are calculated. A control instruction is transmitted. The beam source part and the beam detecting collecting part are fixed at two ends of the rotation control part. According to the control instruction, the beam source part radiates beam, the beam detecting collecting part collects the projection image of beam after transmitting the sample. The projection image is executed with imaging. The invention settles the problems of deformation and motion artifact caused by sample rotation.
Description
Technical field
The present invention relates to the biomedical imaging technology, particularly toy is carried out the imaging system and the method for digital X-ray transmission imaging, tomoscan imaging and three-dimensional imaging.
Background technology
Digital X-ray transmission imaging technology is comparatively sophisticated at present medical imaging technology, and has been successfully applied to clinical.This technology has very important effect for the research of osseous tissue, can provide toy detailed structural information.Minitype CT, also the someone is referred to as micro-CT, with hospital with the difference of CT mainly is on spatial resolution.Hospital is generally the millimeter magnitude with the spatial resolution of CT, and the spatial resolution of micro-CT can reach the micron number magnitude.
Application number is that 200510135935.1 Chinese invention patent application discloses a kind of X-CT scanning system, comprise main control and data handling machine, base, object turntable and machine control unit thereof, X-ray generator and data collecting system, wherein the detector array of detector is arranged vertically with respect to the x-ray source and the object turntable line of centres of X-ray generator, and a side of detector array is concordant with the extended line of the object turntable line of centres or exceed a part with respect to the x-ray source of X-ray generator, and this exceeds the radius of the length of part less than the object turntable.The characteristics of this CT system are the sample rotations, and light source and detector are motionless, this imaging mode is in the process of taking toy, in case animal specimen is moved, profile will produce deformation because of the motion distortion, like this in the process of continuous rotating and projection, animal specimen is in the state of motion deformation all the time, can produce tangible pseudo-shadow with respect to the immobilized projection state of animal, this pseudo-shadow is called motion artifacts, and this motion artifacts brings very big influence can for the shooting effect of sample.
Summary of the invention
In view of this, the object of the present invention is to provide imaging system and method, be used for solving the deformation and the motion artifacts problem that take place in the toy CT imaging process that prior art exists.
The invention provides a kind of imaging system, it comprises:
The sample object stage is used to place the sample that needs imaging;
The radiographic source part is used for divergent-ray;
The X-ray detection X collecting part is used to receive ray image;
Fixedly connected respectively described radiographic source part of Spin Control part, these Spin Control part two ends and X-ray detection X part are used to drive described radiographic source part and X-ray detection X partial rotation;
Computer is used for to described radiographic source part, Spin Control part and X-ray detection X collecting part sending controling instruction, and receives the image that described X-ray detection X collecting part receives and carry out imaging processing.
The present invention also provides a kind of formation method, and this method comprises:
The imaging requirements of A, input expectation is calculated relevant parameter, sending controling instruction;
B, radiographic source part and the two ends of X-ray detection X partial fixing in the Spin Control part, according to described control instruction, radiographic source part divergent-ray, X-ray detection X are partly gathered the projected image after transmission of radiation is crossed sample;
C, described projected image is carried out imaging processing.
As from the foregoing, in imaging system provided by the invention and the method, X-ray detector, object stage and x-ray source are arranged in order from the bottom to top, they be centered close on the same straight line, x-ray source and detector are fixed on the runing rest two ends, make circular motion around sample.Like this, when adopting method of the present invention to carry out the sample shooting, sample keeps the natural form of horizontal stationary in data acquisition, rotate in the process of image data around sample at x-ray source and detector, sample remains initial form, has eliminated the motion artifacts of the toy deformation that produces owing to motion in the sample rotation acquisition system.
Description of drawings
Fig. 1 is the imaging system structure chart in the embodiment of the invention;
Fig. 2 is the structure chart of the radiographic source controller in the embodiment of the invention;
Fig. 3 is the structure chart of the rotary frame in the embodiment of the invention;
Fig. 4 is the vertical view of the flat panel detector fixed mount on the rotary frame and little focus radiographic source fixed mount in the embodiment of the invention;
Fig. 5 is the flow chart of formation method in the embodiment of the invention;
Fig. 6 is the perspective projection figure of experimental rat in the embodiment of the invention;
Fig. 7 is a tension fault image of rebuilding on Fig. 5 median-plane location in the embodiment of the invention;
Fig. 8 carries out the three-dimensional design sketch of drawing behind the three-dimensional reconstruction to the experimental rat head in the embodiment of the invention.
The specific embodiment
The embodiment of the invention provides the system and method that toy is carried out imaging, utilize light source and detector rotation mode to replace the sample rotation mode, keep sample static, light source and detector rotate around it, have solved deformation and motion artifacts problem that the sample rotation brings.
For making the purpose, technical solutions and advantages of the present invention clearer, the present invention is described in further detail below in conjunction with accompanying drawing.
As shown in Figure 1, the imaging system that provides of the embodiment of the invention specifically comprises:
Computer 1, motor driver 2, electric rotary machine structure 3, radiographic source controller 4, microfocus X-ray source 5, data acquisition equipment 6, flat panel detector 7, rotary frame 8, sample object stage 10.
Microfocus X-ray source 5 links to each other with an interface of radiographic source controller 4, and another interface of radiographic source controller 4 links to each other with the COM1 of computer 1; Flat panel detector 7 links to each other with data acquisition equipment 6, and data acquisition equipment 6 links to each other with computer 1 by data line.
Microfocus X-ray source 5 and flat panel detector 7 are fixed on the two ends of rotary frame 8, and rotary frame 8 is installed on the electric rotary machine structure 3, and electric rotary machine structure 3 directly is fixed on the base, lays on the ground by base then.One interface of motor driver 2 links to each other with electric rotary machine structure 3, and another interface links to each other with the COM1 of computer 1.
Sample object stage 10 directly is fixed on the base.
Wherein,
Computer 1 is used for being provided with and to radiographic source controller 4 and motor driver 2 sending controling instructions, and receives the digital X-ray image that data acquisition equipment 6 sends, and this image is carried out imaging processing.
Motor driver 2, link to each other with computer 1 by communication serial port, be used for the control instruction that receiving computer 1 sends, instruction according to computer 1 transmission, by the rotation of driving cable drive electric rotary machine structure 3, thus the rotation of the microfocus X-ray source 5 at driven rotary frame 8 two ends and flat panel detector 7.Described control instruction can be for being provided with the instruction of rotary speed and rotation number of steps, after motor driver 2 parsing serial ports instruct, according to the rotation of information-driven electric rotary machine structures 3 such as rotary speed of carrying in the control instruction and number of steps.
Electric rotary machine structure 3 is used under the driving of motor driver, drives the rotation of the microfocus X-ray source 5 and the flat panel detector 7 at its two ends.This electric rotary machine structure can be motor or servomotor.
Radiographic source controller 4 links to each other with computer 1 by the communication parallel port, and this communication parallel port can be LPT.Radiographic source controller 4 is used for the control instruction that receiving computer 1 sends, the power supply of control microfocus X-ray source 5 logical and disconnected, and power supply general rule radiographic source sends ray, the disconnected ray emission of then interrupting of power supply.When radiographic source controller 4 receives the instruction that microfocus X-ray source 5 that computer 1 sends leaves, microfocus X-ray source 5 sends ray, at this moment at first can select the focus size of the microfocus X-ray source 5 of needs, at the magnitude of voltage of the selected ray tube in the selected back of microfocus X-ray source 5 focus size, in certain scope, determine the tube current value at last.
The structure of radiographic source controller 4 and with the connected mode of microfocus X-ray source 5 as shown in Figure 2, it realizes that principle is: by the Transistor-Transistor Logic level of parallel port, drive the winding coil of relay, connect or turn-off the 220V power supply circuits.This structure comprises with the lower part:
Computer communication parallel port 11 is used for the high-low level of the representative control instruction that receiving computer 1 sends;
Dc source 13 is used to provide digit reverse device 12 and audion 14 required voltages.
Light emitting diode 15, the electromagnetism winding parallel connection of light emitting diode 15 and relay 17 as signal lamp, is used to refer to the break-make situation of relay contact switch, if the contact switch conducting, then light emitting diode 15 is luminous.
Alternating current power supply 16 under the situation that relay 17 leaves, is little focus radiographic source energising.
When computer sends the high level that little focus radiographic source opens, connect digital reverser output low level by holding wire, this moment, the dc source electric current was amplified in the audion conducting, the display lamp of trigger relay and little focus radiographic source switch, can be communicated with the alternating current circuit at little focus radiographic source place after relay triggers, this moment, little focus radiographic source sent ray; Otherwise when computer sends the low level of little focus radiographic source pass, connect digital reverser output high level by holding wire, this moment, audion was not switched on, relay is not worked under the dc source of low current, little focus radiographic source place alternating current circuit is in off state, and little focus radiographic source is not launched X ray.
Microfocus X-ray source 5 is used under the control of radiographic source controller 4, to toy sample emission X ray.The focus of microfocus X-ray source 5 is in 1 micron-100 micrometer range, and tube voltage is in 10 kilovolts-100 kilovolt range.
Data acquisition equipment 6, link to each other with computer 1 by the PCI slot, and link to each other with flat panel detector 7 by digital interface, the connection of the flat panel detector 7 that the one side receiving computer sends, the pretreatment of flat panel detector, the control instructions such as data acquisition of flat panel detector, receive the projected image after object is crossed in X ray transmission that flat panel detector 7 detects on the other hand, and send to computer 1.Like this, computer 1 just can be controlled the work of flat panel detectors by data acquisition equipment 6, and the data of pick-up probe collection.
Flat panel detector 7, flat panel detector 7 and microfocus X-ray source 5 are fixed on the two ends of rotary frame 8 together, be used to survey the X ray that microfocus X-ray source 5 sends, sample 9 backs that this transmission of radiation is crossed above the sample stage 10 are received by flat panel detector 7, are sent to data acquisition equipment 6 by data line again.This flat panel detector 7 can be non-crystalline silicon flat panel detector or amorphous selenium flat-bed detector.
Rotary frame 8, two ends are fixedly connected microfocus X-ray source 5 and flat panel detector 7 respectively, and the middle part links to each other with electric rotary machine structure 3, can rotate under the drive of electric rotary machine structure 3.In the imaging process to the toy sample, microfocus X-ray source 5 and flat panel detector 7 made circular motion around rotary frame 8, thereby to the imaging of sample multi-angle, sample is static can eliminate the motion artifacts that the sample motion brings again.
The structure of rotary frame 8 as shown in Figure 3 and Figure 4, rotary frame 8 mainly is to be that the section bar of FSA-181A is built with the 40mm*40mm model, marks unit among concrete size such as Fig. 3: rice.Mainly comprise vertical rotation bracing frame, little focus radiographic source fixed mount and flat panel detector fixed mount, left figure (a) is the front view of rotary frame in Fig. 3, right figure (b) is the side view of rotary frame, and A among Fig. 4 and B are respectively the vertical view of flat panel detector fixed mount and little focus radiographic source fixed mount.Be to fix between rotation bracing frame, little focus radiographic source fixed mount and the flat panel detector fixed mount vertically by the T-nut of M8.Trouble repaints the dotted line among Fig. 4 once, otherwise prints unclear
Sample object stage 10 is used to place the toy sample.When taking imaging, tested toy sample 9 flat crouching on sample object stage 10, sample stage 10 is that D translation platform is formed, so the position of sample object stage can adjust, and purpose is in order to guarantee that sample 9 is in the center of rotation of microfocus X-ray source 5 and flat panel detector 7.
By above imaging system, utilize light source and detector rotation mode to replace the sample rotation mode, keep sample static, light source and detector rotate around it, have solved deformation and motion artifacts problem that the sample rotation brings.The present invention obtains even more ideal toy image to have created advantage, for research toy structural information provides effective research tool.
Fig. 5 is the flow chart of the formation method that provides of the embodiment of the invention, may further comprise the steps:
Step 501, user import the imaging requirements of expectation.Mainly be to import necessary parameter by the user to computer, comprise sample length, required resolution etc., sample length is the total length that needs imaging object, and required resolution is the spatial resolution of finally rebuilding slicing image.
Step 503, open radiographic source.Computer control x-ray source emission X ray, and radiographic source is opened always in the whole data collection process.
The projection of step 505, collection one frame X ray.
Are step 506, shooting finished? if also do not finish, then execution in step 504; Otherwise carry out next step.
Be example with a concrete shooting experiment below, set forth the effect of above embodiment.The biomaterial of this experiment is the SD rat, removes tail length and is about 100mm.Animal feeding and experiment require to carry out in strict accordance with People's Republic of China's " management of laboratory animal regulations ".Keep flat on the object stage after rat anaesthetized.Adjust the position of object stage, make imaging region just in time aim at the head of rat.
X-ray source voltage is 70 kilovolts, and electric current is 0.3 milliampere; Image taking speed was 1 frame/second.Fig. 6 is the perspective projection figure of an experimental rat, and the skeleton of rat head and profile are all very clear, and the brightness and contrast is very desirable.Fig. 6 is a tension fault image of rebuilding on Fig. 5 median-plane location, can clearly distinguish skeleton and the soft tissue of rat from tomograph, and the image of object stage is also very clear.Fig. 8 is after gathering multiple image, and rat head is carried out the three-dimensional design sketch of drawing behind the three-dimensional reconstruction, and skull, vertebra, omoplate, fore paw are all very clear.
As from the foregoing, imaging system provided by the invention and method, X-ray detector, object stage and x-ray source are arranged in order from the bottom to top, they be centered close on the same straight line, x-ray source and detector are fixed on the runing rest two ends, make circular motion around sample.Like this, when adopting method of the present invention to carry out the sample shooting, sample keeps the natural form of horizontal stationary in data acquisition, rotate in the process of image data around sample at x-ray source and detector, sample remains initial form, compare the immobilized CT of sample rotation, x-ray source and detector system, eliminated the motion artifacts of the toy deformation that produces owing to motion in the sample rotation acquisition system.
Claims (10)
- [claim 1] a kind of imaging system is characterized in that, this system comprises:The sample object stage is used to place the sample that needs imaging;The radiographic source part is used for divergent-ray;The X-ray detection X collecting part is used to receive ray image;Fixedly connected respectively described radiographic source part of Spin Control part, these Spin Control part two ends and X-ray detection X part are used to drive described radiographic source part and X-ray detection X partial rotation;Computer is used for to described radiographic source part, Spin Control part and X-ray detection X collecting part sending controling instruction, and receives the image that described X-ray detection X collecting part receives and carry out imaging processing.
- [claim 2] system according to claim 1 is characterized in that, described sample object stage is made up of a D translation platform, and the position can be adjusted, and is used to guarantee that sample is positioned at described radiographic source part and X-ray detection X center of rotation partly.
- [claim 3] system according to claim 2 is characterized in that, this system further comprises:The radiographic source controller is used for the control instruction that receiving computer sends, and controls described radiographic source part divergent-ray and interrupts ray emission.
- [claim 4] system according to claim 3 is characterized in that, described radiographic source controller specifically comprises:Computer communication parallel port is used for the high-low level of the representative control instruction that receiving computer sends;Digital inverter is used for changing the high level that computer 1 sends into low level, and low level changes high level into;Dc source is used to provide described digit reverse device and audion required voltage;Audion, base stage connect described phase inverter, and colelctor electrode connects described dc source, are used for the electric current of described dc source is amplified and trigger relay;Alternating current power supply is used for partly charging for described radiographic source under the situation of relay conducting;Relay is used for triggering described radiographic source circuit working state partly by break-make.
- [claim 5] system according to claim 4 is characterized in that, this system further comprises:Light emitting diode, in parallel with the electromagnetism winding of described relay, be used for the break-make situation of under the triggering of described audion indicating relay, then luminous during conducting.
- [claim 6] is characterized in that according to any described system in the claim 1 to 5 this system further comprises:Motor driver is used for the control instruction that receiving computer sends, and controls described Spin Control and partly drives radiographic source part and X-ray detection X partial rotation.
- [claim 7] system according to claim 6 is characterized in that, this system further comprises:Data acquisition equipment is used to receive the ray image that described X-ray detection X collecting part collects and sends to computer, and the duty that receives the control instruction control X-ray detection X collecting part of described computer.
- [claim 8] system according to claim 7 is characterized in that, the focus of described radiographic source part is in 1 micron-100 micrometer range, and tube voltage is in 10 kilovolts-100 kilovolt range.
- [claim 9] a kind of formation method is characterized in that, this method comprises:The imaging requirements of A, input expectation is calculated relevant parameter, sending controling instruction;B, radiographic source part and the two ends of X-ray detection X partial fixing in the Spin Control part, according to described control instruction, radiographic source part divergent-ray, X-ray detection X are partly gathered the projected image after transmission of radiation is crossed sample;C, described projected image is carried out imaging processing.
- [claim 10] method according to claim 9 is characterized in that, described radiographic source part is partly partly made circular motion around Spin Control with X-ray detection X, to the imaging of described sample multi-angle.
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| CNA2009103001151A CN101455574A (en) | 2009-01-08 | 2009-01-08 | Imaging system and method |
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| CNA2009103001151A CN101455574A (en) | 2009-01-08 | 2009-01-08 | Imaging system and method |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319083A (en) * | 2011-08-01 | 2012-01-18 | 中国人民解放军第四军医大学 | Wide-FOV (field of view) and low-dose Micro-CT (computed tomography) cone beam imaging system |
| CN104641246A (en) * | 2012-09-21 | 2015-05-20 | 西门子公司 | Hybrid examination system having an MR scanner, an x-ray source and an x-ray detector |
| CN105943071A (en) * | 2016-05-25 | 2016-09-21 | 厦门大学 | X-ray ct imaging system |
| CN106353350A (en) * | 2016-09-30 | 2017-01-25 | 北京纳米维景科技有限公司 | Reverse geometric imaging experimental platform |
| CN108508042A (en) * | 2018-04-02 | 2018-09-07 | 合肥工业大学 | Multi-view X ray coal and spoil transmission image detection method and device |
| CN110225247A (en) * | 2019-05-29 | 2019-09-10 | 联想(北京)有限公司 | A kind of image processing method and electronic equipment |
| CN110567996A (en) * | 2019-09-19 | 2019-12-13 | 方正 | Transmission imaging detection device and computer tomography system using same |
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2009
- 2009-01-08 CN CNA2009103001151A patent/CN101455574A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319083A (en) * | 2011-08-01 | 2012-01-18 | 中国人民解放军第四军医大学 | Wide-FOV (field of view) and low-dose Micro-CT (computed tomography) cone beam imaging system |
| CN104641246A (en) * | 2012-09-21 | 2015-05-20 | 西门子公司 | Hybrid examination system having an MR scanner, an x-ray source and an x-ray detector |
| US10838030B2 (en) | 2012-09-21 | 2020-11-17 | Siemens Healthcare Gmbh | Hybrid examination system having an MR scanner, an X ray source and an X ray detector |
| CN105943071A (en) * | 2016-05-25 | 2016-09-21 | 厦门大学 | X-ray ct imaging system |
| CN106353350A (en) * | 2016-09-30 | 2017-01-25 | 北京纳米维景科技有限公司 | Reverse geometric imaging experimental platform |
| CN108508042A (en) * | 2018-04-02 | 2018-09-07 | 合肥工业大学 | Multi-view X ray coal and spoil transmission image detection method and device |
| CN110225247A (en) * | 2019-05-29 | 2019-09-10 | 联想(北京)有限公司 | A kind of image processing method and electronic equipment |
| CN110567996A (en) * | 2019-09-19 | 2019-12-13 | 方正 | Transmission imaging detection device and computer tomography system using same |
| CN110567996B (en) * | 2019-09-19 | 2022-09-27 | 方正 | Transmission imaging detection device and computer tomography system using same |
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