CN101437443B - 生物传感器用的异常输出检测系统 - Google Patents

生物传感器用的异常输出检测系统 Download PDF

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Publication number
CN101437443B
CN101437443B CN2007800162447A CN200780016244A CN101437443B CN 101437443 B CN101437443 B CN 101437443B CN 2007800162447 A CN2007800162447 A CN 2007800162447A CN 200780016244 A CN200780016244 A CN 200780016244A CN 101437443 B CN101437443 B CN 101437443B
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pulse
input signal
output signal
test
poll
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CN101437443A (zh
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史考特·E·卡本特
克里斯廷·D·纳尔森
伍焕平
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Bayer Healthcare LLC
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Bayer Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/10—Analysis or design of chemical reactions, syntheses or processes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Electrochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Physiology (AREA)
CN2007800162447A 2006-05-08 2007-05-07 生物传感器用的异常输出检测系统 Active CN101437443B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74677106P 2006-05-08 2006-05-08
US60/746,771 2006-05-08
PCT/US2007/068320 WO2007133985A2 (en) 2006-05-08 2007-05-07 Abnormal output detection system for a biosensor

Publications (2)

Publication Number Publication Date
CN101437443A CN101437443A (zh) 2009-05-20
CN101437443B true CN101437443B (zh) 2011-11-30

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CN2007800162447A Active CN101437443B (zh) 2006-05-08 2007-05-07 生物传感器用的异常输出检测系统

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US (2) US8234076B2 (enExample)
EP (1) EP2020909A2 (enExample)
JP (2) JP5121822B2 (enExample)
CN (1) CN101437443B (enExample)
BR (1) BRPI0711433A2 (enExample)
CA (1) CA2650880C (enExample)
MX (1) MX2008014250A (enExample)
NO (1) NO20084960L (enExample)
RU (1) RU2465812C2 (enExample)
TW (1) TWI431273B (enExample)
WO (1) WO2007133985A2 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3172559B2 (ja) 1991-11-20 2001-06-04 株式会社クラレ 艶消しフィルム
BRPI0507376A (pt) 2004-02-06 2007-07-10 Bayer Healthcare Llc espécie oxidável como uma referência interna para biossensores e método de uso
US8529751B2 (en) 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
WO2007133995A2 (en) 2006-05-08 2007-11-22 The Lubrizol Corporation Lubricating composition containing a polymer and antiwear agents
RU2465812C2 (ru) * 2006-05-08 2012-11-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Система детектирования аномального выходного сигнала для биосенсора
US8778168B2 (en) 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
EP2223104B1 (en) 2007-12-10 2018-08-29 Ascensia Diabetes Care Holdings AG Slope-based compensation
CA2707300C (en) 2007-12-10 2017-09-26 Bayer Healthcare Llc Rapid-read gated amperometry
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
US8603768B2 (en) 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
US8551320B2 (en) 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
WO2010077660A1 (en) * 2008-12-08 2010-07-08 Bayer Healthcare Llc Biosensor system with signal adjustment
DE102009048811B4 (de) * 2009-10-08 2013-07-18 Eads Deutschland Gmbh Biosensorvorrichtung mit Selbsttesteinrichtung
MX2012010860A (es) 2010-03-22 2013-03-05 Bayer Healthcare Llc Compensacion residual para un biosensor.
KR102068949B1 (ko) 2010-06-07 2020-01-21 바이엘 헬쓰케어 엘엘씨 2차 출력 신호를 포함하는 기울기-기반 보상
BR112012031375A2 (pt) 2010-06-07 2016-10-25 Bayer Healthcare Llc sistema de gerenciamento de enchimento abaixo do necessário para um biosensor
US8923918B2 (en) * 2010-12-18 2014-12-30 Kallows Engineering India Pvt. Ltd. Biosensor interface apparatus for a mobile communication device
US9008744B2 (en) * 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
EP2758039B1 (en) 2011-09-21 2018-01-24 Ascensia Diabetes Care Holdings AG Biosensor with error compensation
US9810688B2 (en) * 2013-03-15 2017-11-07 Robert Bosch Gmbh Smart glass slide for microarrays
US9080196B2 (en) * 2012-09-28 2015-07-14 Cilag Gmbh International System and method for determining hematocrit insensitive glucose concentration
US9005426B2 (en) 2012-09-28 2015-04-14 Cilag Gmbh International System and method for determining hematocrit insensitive glucose concentration
EP3276355B1 (en) * 2013-03-14 2020-05-06 Ascensia Diabetes Care Holdings AG Normalized calibration of analyte concentration determinations
CN105283757B (zh) * 2013-03-15 2019-04-23 豪夫迈·罗氏有限公司 对分析物的电化学测量进行防故障的方法以及结合该方法的设备、装置和系统
CA2900572C (en) * 2013-03-15 2018-02-13 F. Hoffmann-La Roche Ag Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom as well as devices, apparatuses and systems incorporting the same
CN104122882A (zh) * 2013-04-24 2014-10-29 中烟机械技术中心有限责任公司 巴鲁夫自诊断型传感器的故障诊断系统
TWI567387B (zh) 2014-09-12 2017-01-21 達爾生技股份有限公司 電化學的感測試片本身性質之異常的檢測方法
CN105445341B (zh) * 2014-09-12 2018-10-16 达尔生技股份有限公司 电化学的检测试片异常的检测方法
JP7062954B2 (ja) * 2016-02-10 2022-05-09 ソニーグループ株式会社 血液凝固解析装置及び血液凝固解析方法
WO2018104835A1 (en) * 2016-12-05 2018-06-14 Ascensia Diabetes Care Holdings Ag Risk factor monitoring
KR102031340B1 (ko) * 2018-03-14 2019-10-11 주식회사 필로시스 혈당 측정 장치, 방법, 및 시스템
US11382541B2 (en) 2018-11-16 2022-07-12 Medtronic Minimed, Inc. Miniaturized analyte sensor
CN112294318B (zh) * 2019-08-02 2024-08-20 华广生技股份有限公司 植入式微型生物传感器及其制法
TWI870545B (zh) * 2020-02-21 2025-01-21 美商半導體組件工業公司 用於測量工作電極電流之方法、雙向恆電位器、及電池測量系統
CN111681713B (zh) * 2020-06-10 2023-03-31 重庆邮电大学 一种包含退相干作用的聚合物分子电学性质的模型构建方法及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014026A1 (en) * 1994-11-04 1996-05-17 Elan Medical Technologies Limited Analyte-controlled liquid delivery device and analyte monitor
US6576117B1 (en) * 1998-05-20 2003-06-10 Arkray Method and apparatus for electrochemical measurement using statistical technique
CN1426535A (zh) * 2000-03-08 2003-06-25 因弗内斯医疗有限公司 液体中物质的测量

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4750496A (en) 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
US5508171A (en) 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
US5243516A (en) * 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
FR2701117B1 (fr) 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
ATE227844T1 (de) 1997-02-06 2002-11-15 Therasense Inc Kleinvolumiger sensor zur in-vitro bestimmung
US6391645B1 (en) 1997-05-12 2002-05-21 Bayer Corporation Method and apparatus for correcting ambient temperature effect in biosensors
DK1135188T3 (da) * 1998-11-02 2008-03-31 Alza Corp Elektrotransportindretning omfattende et kompatibelt, antimikrobielt stof
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
DE60334365D1 (de) * 2002-03-22 2010-11-11 Animas Technologies Llc Leistungsverbesserung einer analytenüberwachungsvorrichtung
US20040222967A1 (en) * 2003-05-05 2004-11-11 Riccomini Roy J. System and method for controlling polling of a signal in a hand-held computing device
US7488601B2 (en) * 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
JP5065013B2 (ja) 2004-05-14 2012-10-31 バイエル・ヘルスケア・エルエルシー グルコースアッセイにおいてヘマトクリットの調整を行う方法、およびそのための装置
BRPI0613592A2 (pt) 2005-07-20 2011-01-18 Bayer Healthcare Llc amperometria conectada por porta
WO2007040913A1 (en) 2005-09-30 2007-04-12 Bayer Healthcare Llc Gated voltammetry
RU2465812C2 (ru) * 2006-05-08 2012-11-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Система детектирования аномального выходного сигнала для биосенсора

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014026A1 (en) * 1994-11-04 1996-05-17 Elan Medical Technologies Limited Analyte-controlled liquid delivery device and analyte monitor
US6576117B1 (en) * 1998-05-20 2003-06-10 Arkray Method and apparatus for electrochemical measurement using statistical technique
CN1426535A (zh) * 2000-03-08 2003-06-25 因弗内斯医疗有限公司 液体中物质的测量

Also Published As

Publication number Publication date
US9301717B2 (en) 2016-04-05
RU2465812C2 (ru) 2012-11-10
US8234076B2 (en) 2012-07-31
WO2007133985A3 (en) 2008-01-10
TWI431273B (zh) 2014-03-21
HK1132643A1 (en) 2010-03-05
CA2650880C (en) 2015-11-24
JP5121822B2 (ja) 2013-01-16
TW200804805A (en) 2008-01-16
NO20084960L (no) 2008-11-26
CA2650880A1 (en) 2007-11-22
US20090099787A1 (en) 2009-04-16
JP2009536744A (ja) 2009-10-15
MX2008014250A (es) 2008-11-26
EP2020909A2 (en) 2009-02-11
JP2012255803A (ja) 2012-12-27
JP5373948B2 (ja) 2013-12-18
CN101437443A (zh) 2009-05-20
BRPI0711433A2 (pt) 2011-11-16
RU2008148133A (ru) 2010-06-20
US20120271559A1 (en) 2012-10-25
WO2007133985A2 (en) 2007-11-22

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