CN101411847A - Medicinal composition for treating hepatitis and preparation method thereof - Google Patents

Medicinal composition for treating hepatitis and preparation method thereof Download PDF

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Publication number
CN101411847A
CN101411847A CNA2008101477116A CN200810147711A CN101411847A CN 101411847 A CN101411847 A CN 101411847A CN A2008101477116 A CNA2008101477116 A CN A2008101477116A CN 200810147711 A CN200810147711 A CN 200810147711A CN 101411847 A CN101411847 A CN 101411847A
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hepatitis
radix
treatment
pharmaceutical composition
preparing
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张兴仕
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention relates to a pharmaceutical composition for treating hepatitis and a method for preparing the same, which belongs to the pharmaceutical composition, in particular to a drug prepared by using plant Chinese medicines as raw materials and the method for preparing the same. The raw materials for preparing active ingredients of the drug comprise herba artenisiae capillaris, radix astragali, immature tangerine, herba scutellariae barbatae, almond, platycodon grandiflorum, radix paeoniae rubra, radix sophorae flavescentis, isatis root, rhizoma coptidis and the like. The method for preparing the drug is to mix the medicines together, process the mixture into fine powder, and make the powder into capsules, water pills, honeyed pills, oral liquid, tablets or particles. The drug can treat viral hepatitis A and hepatitis B, and inappetence resulted from upper, middle, and lower warmers and moist heat. The curative ratio is high and the medicine cost is low.

Description

A kind of pharmaceutical composition for the treatment of hepatitis and preparation method thereof
(1) technical field:
A kind of pharmaceutical composition for the treatment of hepatitis and preparation method thereof belongs to pharmaceutical composition, and especially relating to a kind of is the medicine that raw material is made with the botanical herbs, and its preparation method.
(2) background technology:
Hepatitis, particularly Type B viral hepatitis are big diseases of serious harm human health, and existing more than 20 hundred million people are infected in the whole world, about 300,000,000 5 thousand ten thousand people become chronic HBV infection person.Liver cirrhosis and hepatocarcinoma take place in chronic carrier then, and ten thousand patients died from hepatopathy surplus the whole world had 100 an every year, and China accounts for 1/3rd.Just so far, the also desirable without comparison and advanced specific medicament that can effect a radical cure Type B viral hepatitis in the whole world.The sick existing thousands of years history of Chinese medicine chronic hepatitis, the medicine of screening treatment viral hepatitis seems very important from Chinese medicine.The inventor discloses the patent No. in 2003 be 03102052.6 " a kind of pharmaceutical composition for the treatment of hepatitis ", the raw material of this pharmaceutical composition comprises Herba Artemisiae Scopariae, Radix Astragali, Pericarpium Citri Reticulatae Viride, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Rhizoma Atractylodis Macrocephalae (parched), Hirudo, Fructus Amomi Rotundus, Radix Curcumae etc., to viral first, b hepatitis, and liver, gallbladder, stomach damp-heat in lower-JIAO and be off one's feed remarkable result is arranged, the cure rate of hepatitis is reached 98.9%.But this pharmaceutical composition also exists following shortcoming to overcome:
1, this medical material of Hirudo is relatively more expensive, has increased the cost of medicine, has strengthened patient's financial burden;
2, the cure rate to hepatitis also should improve again, to trend towards effecting a radical cure hepatitis.
(3) goal of the invention:
The problem to be solved in the present invention is exactly to provide a kind of cure rate to improve the pharmaceutical composition of the treatment hepatitis that medicine is with low cost, and its preparation method at above deficiency.Its technical scheme is as follows:
Prepare the raw material that its active component raw material comprises following weight portion:
Herba Artemisiae Scopariae 50--70, Radix Astragali 20--40, Pericarpium Citri Reticulatae Viride 10--30, Herba Scutellariae Barbatae 20--40, Herb Gynostemmae Pentaphylli 20--40, Rhizoma Atractylodis Macrocephalae 10--20, Fructus Amomi Rotundus 7--17, Radix Curcumae 10--20, Saussurea lappa Clarke 10--20, seed of Job's tears 40--60, Semen Armeniacae Amarum 10--30, Radix Platycodonis 10--20, Radix Paeoniae Rubra 10--30, Radix Sophorae Flavescentis 20--40, Radix Isatidis 20--40, Rhizoma Coptidis 10--20, LIANBENSHUANGZHI DIWAN 400--500 grain.
Its preparation method is above-mentioned each medicine to be mixed post-treatment simultaneously become fine powder, makes capsule, water pill, honeyed pill, oral liquid, tablet or granule.
Clinical drug of the present invention uses the result to show that its beneficial effect is:
1, compatibility of drugs of the present invention use the marrow of Chinese medicine dialectical execute administer that the opinion principle takes place with the human internal organ disease, the mutual relation identification of etiology according to differenciation of symptoms and signs of development, variation, in conjunction with modern pathology, virus, molecule, pharmacokinetics etc., screening natural plants, animal, mineral, biological medicine, extensively design, repetition test, compatibility and getting repeatedly, most medicines have the effect of removing HbeAg and HBv, DNA in the serum in the prescription.So, main medicine in the side shows to have the liver circulation of improvement, promote the hepatocyte blood flow through modern pharmacological research, improve caused hepatocyte anoxia of liver arteriolospasm and cell regeneration, adjust immunologic function, collaborative inhibition hepatic fibrosis, alleviate low albumen disease, increase myocardial contraction, improve the painstaking effort stroke volume, strengthen the Hepatic artery blood volume, promote the liver internal recycle, increase oxygen supply, improve hepatocyte function, improve bile viscosity in the liver and gall, improve the permeability of intracapsular bile of gallbladder, further reach and recover the normal of liver function.Based on above-mentioned principle, under the dialectical guidance of principle of Chinese medicine, science, rationalization compatibility by all medicines, heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, eliminates the phlegm, gets rid of evils and set upright etc. at the dampness removing diuresis, play good effect altogether, make the cure rate of hepatitis reach 99.59%, level off to radical cure hepatitis, have good social benefit and economic benefit.
2, all medicine raw materials are based on natural plants, the prescription wide material sources, and production technology is simple, and equipment infusion of financial resources risk is low, and the medicine cost is low, has alleviated patient's financial burden.
3, pharmacology proof Radix Paeoniae Rubra removing blood stasis and activating blood flow, pain relieving removing fire from the liver, to menoxenia, the stasis of blood stagnate, stomachache, amenorrhea, lump in the abdomen, carbuncle pyogenic infections from tumour or sore, chest and hypochondrium, conjunctival congestion etc. all have good effect; Radix Sophorae Flavescentis clearing away heat and cooling blood, wind dispelling parasite killing, remarkable to dysentery, jaundice, yellowish or reddish urine, skin wind heat, malignant boil mange effect; Radix Isatidis clearing away heat and cooling blood, subduing swelling and detoxicating, calentura is sent out speckle, laryngopharynx swelling and pain, epidemic infection with swollen head, haematemesis, epistaxis all remarkable efficacy; Rhizoma Coptidis pathogenic fire purging dampness, relieving restlessness detoxifcation,, feeling of fullness vexed to intenseness of heat, quench one's thirst, hematodiarrhoea stomachache, lining disease are thick and heavy, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus, aphtha curative effect are splendid.More than each medicine rationalize compatibility, the cure rate that improves hepatitis has been played positive effect.
Medicament sources:
Herba Artemisiae Scopariae has another name called western Herba Artemisiae Scopariae, and tender Herba Artemisiae Scopariae, Herba Artemisiae Scopariae, Cotton Herba Artemisiae Scopariae, Herba Artemisiae Sieversianae, floss Artemisia, monkey hair go the root seedling for Compositae mugwort Herba Artemisiae Scopariae or BINHAO (northern Herba Artemisiae Scopariae).
The Radix Astragali has another name called continuous stilbene, the continuous Radix Astragali, Radix Astragali, is the pulse family Astragalus, the root of Radix Astragali and astragalus mongholicus Bge.
Pericarpium Citri Reticulatae Viride has another name called Pericarpium Citri tangerinae, is Rutaceae, and sweet Fructus Citri tangerinae platymiscium Fructus Citri tangerinae is used as medicine with the young tender fruit processing of landing voluntarily.
Herba Scutellariae Barbatae has another name called and the head grass narrow leaf Herba Scutellariae indicae, toothbrush grass, Herba Scutellariae Darbatae, all herbal medicine of Labiatae Scutellaria plant Herba Scutellariae Barbatae.
Herb Gynostemmae Pentaphylli has another name called Herba Gynostemmatis, Herba Gynostemmatis, and Herb Gynostemmae Pentaphylli is the cucurbitaceae genus gynostemma Herb Gynostemmae Pentaphylli, with root and all herbal medicine.
The Rhizoma Atractylodis Macrocephalae has another name called Rhizoma Atractylodis Macrocephalae, winter art, baking art, wide art, clasp art, is feverfew Rhizoma Atractylodis Macrocephalae rhizome.
Fructus Amomi Rotundus has another name called garden Fructus Amomi Rotundus, Fructus Amomi Rotundus, ten and opens coolly, is the dry seed of Zingiberaceae Amomum plant Fructus Amomi Rotundus.
Radix Curcumae has another name called Ma Shu, Huang Yu, is zingiberaceous plant Radix Curcumae tuber.
Saussurea lappa Clarke has another name called Radix Aucklandiae (Radix Vladimiriae), the Radix Aucklandiae, is the root of Compositae Saussurea lappa Clarke platymiscium Saussurea lappa Clarke.
Seed of Job's tears have another name called Semen Coicis, and Semen Coicis, ditch rice, Semen Coicis are the kernel of grass Coix plant Semen Coicis.
Semen Armeniacae Amarum has another name called Semen Armeniacae Amarum, Prunus armeniaca L.var.ansu Maxim., is the seed of rose department cherry genus plant Fructus Pruni and mutation Prunus armeniaca L.var.ansu Maxim..
Radix Platycodonis, have another name called BAIYAO, stalk grass, sharp as, Radix Platycodi, RADIX PLATYCODI etc., be the dry root of campanulaceae Platycodon grandiflouorum.
Radix Paeoniae Rubra has another name called the mountain Radix Paeoniae, Paeonia obovata Maxim..Radix Paeoniae Rubra is the root of Ranunculaceae Paeonia plant peony (wild product), Paeonia obovata Maxim..
Radix Sophorae Flavescentis has another name called wild Chinese scholartree, brave man's branch, bitter bone, bone, Chinese scholartree, Albizzia kalkora.Radix Sophorae Flavescentis is the root of leguminous plant Radix Sophorae Flavescentis.
Radix Isatidis has another name called Da Lan root, Radix Clerodenri Cyrtophylli.Radix Isatidis is the root of Cruciferae Clerodendron plant Isatis indigotica Fort., careless Folium Isatidis.
Rhizoma Coptidis has another name called Rhizoma Coptidis, Rhizoma Coptidis, and flavor connects.Rhizoma Coptidis is the root stock of Ranunculaceae coptis plant Rhizoma Coptidis.
LIANBENSHUANGZHI DIWAN is a kind of organic synthesis thing that falls enzyme.
Medicine of the present invention has following characteristics:
Character: little pale brown color.
Abnormal smells from the patient: gas fragrance is strong, bitter in the mouth, little puckery.
Nature and flavor: bitter, cold, salty, flat, little suffering.
Function: heat-clearing and toxic substances removing, anti-inflammatory and choleretic, dampness removing reduce phlegm, dispersing the stagnated live-QI to relieve the stagnation of QI, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, invigorating the spleen and regulating the stomach, dyspepsia and intestinal stasis relieving, anti-inflammatory analgesic, appetite stimulator, improve immune antibody, inspire enthusiasm etc.
Cure mainly: viral hepatitis A and hepatitis B, and upper, middle and lower three warmers, being off one's feed due to damp and hot.
Usage and consumption: every day 3 times, each 4--6 grain (about 2--3 gram, other dosage form is also abided by this and taken).
Points for attention: asthenic body, appetite difference person, listless (depressed), lusterless complexion, dizzy tinnitus, fatigue, weak pulse, heavy, when empty person takes, available first-class Mel is swallowed towards eliminating cold for resuscitation water, otherwise swallows with eliminating cold for resuscitation water separately.
The course of treatment:
30 days is a course of treatment, and " two double " or DNA test are done in general chemical examination 3 courses of treatment, add after normal 1-3 courses of treatment with consolidation.
For showing the therapeutic effect of medicine of the present invention to hepatitis, the inventor has done the clinical observation of system to 486 routine patients:
Physical data:
486 routine patients all are the outpatient, and the shortest 3 courses of treatment, the longest 7 courses of treatment, wherein male: 294 examples are divided into: 6--12 one full year of life 12 example; 13--22 one full year of life 56 example; 23--31 one full year of life 120 example; 32--45 one full year of life 56 example; 46--66 one full year of life 38 example; 67--76 one full year of life 12 example.Women's 192 examples are divided into 8--15 one full year of life 28 example; 16--28 one full year of life 38 example; 29--36 one full year of life 66 example; 37--58 one full year of life 38 example; 59--68 one full year of life 22 example.
Diagnostic criteria: by May nineteen ninety-five Beijing the 5th whole nation infectious disease parasite academicly can the viral hepatitis diagnostic criteria of revising be discussed and prevent and treat scheme, and relevant diagnosis explanation and " two double ", " DNA ", liver function chemical examination etc. are foundation.
Table one diagnosis reference table
The HBsAg hepatitis B surface antigen Anti--HBs anti-hepatitis B surface antigen antibody Hbe Ag hepatitis B E antigen Anti--Hbe anti-hepatitis B E antigen-antibody Anti--HBC anti-hepatitis B cAg antibody Clinical meaning
Positive (+) Positive (+) Positive (+) The acute, chronic hepatitis active stage, be infectious
Positive (+) Positive (+) Positive (+) Infectiousness a little less than convalescent period
Positive (+) Positive (+) Acute hepatitis, chronic HBs Ag carrier
Positive (+) Acute previous infection mistake
Criterion of cure: all signs, transference cure, two double, DNA chemical examination are normal.
Table two is cured recovery canonical reference table
The HBsAg hepatitis B surface antigen Anti--HBs anti-hepatitis B surface antigen antibody Hbe Ag hepatitis B E antigen Anti--Hbe anti-hepatitis B E antigen-antibody Anti--HBC anti-hepatitis B cAg antibody Clinical meaning
Positive (+) Positive (+) Convalescent period
Positive (+) Positive (+) Positive (+) Convalescence
Positive (+) Positive (+) The previous infection mistake has immunity
Positive (+) After the active and passive immunity of convalescent period
Therapeutic outcome:
Treat 486 examples, cure 484 examples, cure rate reaches 99.59%, is respectively " convalescence " person 74 examples 3 courses of treatment; 4 courses of treatment " convalescent period " person's 92 examples; 5 courses of treatment " previous infection has been crossed immunity " person 125 examples; 6 courses of treatment " convalescent period active and passive immunity back " person's 127 examples; 7 courses of treatment " recovery from illness " person 66 examples.
Model case:
Nie xx, the man, 42 years old, the wholesale person of individual general merchandise examined March 28 calendar year 2001.See the thin angel of its shape, the complexion sallow, the binocular xanthochromia, tongue body is skinny and wizened, and tongue is few crimson.Ask it: fatigue tired, row steps unable, and giddy is heavily wrapped up in, and bitter taste is laid one's hand on its right rib hepatosplenomegaly, has a dull ache, and abdominal distention, body weight are gradually light, the nauseating nausea sense of having brushed teeth, big constipation, yellowish or reddish urine such as strong tea sample.Chemical examination " liver function, two double " is: hepatitis B surface antigen (HbsAg)+; Hepatitis B E antigen (HbeAg)+; Anti-hepatitis B cAg antibody (anti---HBC)+; Liver function: SGPT686, TBIL106, TTT12, AST602u, T87, A42, G30.6, every index all increases.Take medicine of the present invention above-mentioned all disease disappearances after 4 months, the every index of liver function is normal; " two double ": anti-hepatitis B E antigen-antibody (anti---Hbe)+; Anti-hepatitis B cAg antibody (anti---HBC)+; Be convalescent period, continue consolidation later in 1 month of clothes medicine of the present invention and announcement more.
Virgin xx, the woman, 54 years old, bright town, Xide County new connection villager examined on March 8th, 2002.The patient on October 12nd, 1988 Xide County hospital chemical examination liver function and two double, the every index of liver function is all higher, and " two double " for a long time: hepatitis B surface antigen (HBsAg)+, hepatitis B E antigen (HbeAg)+, anti-hepatitis B cAg antibody (anti---HBC)+.Belong to chronic hepatitis, active stage, be infectious, and the patient takes the Chinese medicine and western medicine of treatment hepatitis B for a long time for 8 years, is not have to lapse to.Readme: sleep not good enough, fidgety, daytime is dizzy and fatigue, lassitude, the bitter happiness drink of xerostomia is cold, the normal dull pain in hepatic region, splenomegaly is laid one's hand on and there is the tenderness sense hepatic region, and abdominal distention, poor appetite, oliguria are helvolus, constipation is half congealed greatly differs, and it is thin to see its shape, and skin is dark yellow, the binocular xanthochromia, tongue body is skinny and wizened, the few Tianjin of body of the tongue, drying, red tip of the tongue has the purple point of the big decimal grain of the grain of rice, thick, yellow and greasy fur, see prickle more, two rolling pulse strings are heavy, thin.Obey medicine of the present invention after 3 months liver function to chemically examine every index normal substantially, the transaminase is slightly higher; Its hepatitis B surface antigen (HBsAg)+, anti-hepatitis B E antigen-antibody (anti---HBe)+; Anti-hepatitis B cAg antibody (anti---HBC)+.Be convalescent period, weak infectiousness.Continue clothes medicine of the present invention and check after 2 months, the transaminase is 38u, the anti-hepatitis B surface antigen antibody (anti---HBs)+; Anti-hepatitis B cAg antibody (anti---HBC)+.For the previous infection mistake, immunity is arranged.Continuous clothes are strengthened after 1 month consolidating.
What xx, the man, 36 years old, railway station, Xide County family members examined June 12 calendar year 2001, and it is thin to see its patient, angel, body of the tongue extra dry red wine, no fur, two thready and weak pulse.Ask it: fatigue, unable, xerostomia, abdominal distention, poor appetite, dry cough without phlegm, nausea when brushing teeth, constipation, yellowish or reddish urine is short, and it is fidgety to have a sleepless night.Xide County hospital chemical examination liver function is normal, and two double chemical examinations are: hepatitis b surface antigen positive (HBsAg)+; Hepatitis B E antigen positive (HBeAg)+; Anti-hepatitis B cAg antibody positive (anti---HBC)+.Be great three positive, hepatitis B, acute, chronic hepatitis, active stage, be infectious.Throw medicament capsule of the present invention after 3 courses of treatment chemical examination two transfer to for double: the anti-hepatitis B surface antigen antibody positive (anti---HBS)+; Anti-hepatitis B cAg antibody positive (anti---HBC)+.For previous infection has been crossed immunity.Throw 2 courses of treatment again to strengthen consolidation.
Grandson xx, the man, 18 years old, the former granite in the Xide County worker sons and younger brothers of factory, the patient examined October 6 nineteen ninety-five, self-induction abdominal distention, xerostomia, hardship, a burst of dull pain in hepatic region, right side, poor appetite, general weakness, step the row weakness, two thready and weak pulse, cunning are laid one's hand on and all there is the tenderness sense hepatic region, under the liver rib about 3 centimetres.Xide County hospital chemical examination " two double ": hepatitis b surface antigen positive (HBsAg)+; Hepatitis B E antigen positive (HBeAg)+; Anti-hepatitis B cAg antibody positive (anti---HBC)+; Examine and be acute, chronic hepatitis, active stage, be infectious.Throw capsule of the present invention after 4 courses of treatment all diseases of patient disappear, chemical examination " two double " transfers to: the anti-hepatitis B surface antigen antibody positive (anti---HBs)+; Anti-hepatitis B E antigen-antibody (anti---HBE)+; Anti-hepatitis B cAg body (anti---HBc)+; Be convalescence, throw 2 courses of treatment again and heal.
(4) specific embodiment:
Embodiment one:
Take by weighing each medicine by following weight:
Herba Artemisiae Scopariae 50g, Radix Astragali 40g, Pericarpium Citri Reticulatae Viride 10g, Herba Scutellariae Barbatae 40g, Herb Gynostemmae Pentaphylli 20g, Rhizoma Atractylodis Macrocephalae 20g, Fructus Amomi Rotundus 7g, Radix Curcumae 20g, Saussurea lappa Clarke 10g, seed of Job's tears 60g, Semen Armeniacae Amarum 10g, Radix Platycodonis 20g, Radix Paeoniae Rubra 10g, Radix Sophorae Flavescentis 40g, Radix Isatidis 20g, Rhizoma Coptidis 20g, 400 of LIANBENSHUANGZHI DIWAN (1.5 milligrams every).
Its preparation method is:
With above-mentioned each medicine blanking impurity and silt particle, mix post-treatment simultaneously and become 150 order fine powders (generally not sieving), sterilization is dressed up the capsule of every heavy 0.50 gram with " No. zero " capsule.
Embodiment two:
Take by weighing each medicine by following weight:
Herba Artemisiae Scopariae 70g, Radix Astragali 20g, Pericarpium Citri Reticulatae Viride 30g, Herba Scutellariae Barbatae 20g, Herb Gynostemmae Pentaphylli 40g, Rhizoma Atractylodis Macrocephalae 10g, Fructus Amomi Rotundus 17g, Radix Curcumae 10g, Saussurea lappa Clarke 20g, seed of Job's tears 40g, Semen Armeniacae Amarum 30g, Radix Platycodonis 10g, Radix Paeoniae Rubra 30g, Radix Sophorae Flavescentis 20g, Radix Isatidis 40g, Rhizoma Coptidis 10g, 500 of LIANBENSHUANGZHI DIWAN (1.5 milligrams every).
Its preparation method is:
With above-mentioned each medicine blanking impurity and silt particle, mix post-treatment simultaneously and become 150 order fine powders (generally not sieving), make dissolved granule behind the sterilization.
Embodiment three:
Take by weighing each medicine by following weight:
Herba Artemisiae Scopariae 60g, Radix Astragali 30g, Pericarpium Citri Reticulatae Viride 18g, Herba Scutellariae Barbatae 30g, Herb Gynostemmae Pentaphylli 30g, Rhizoma Atractylodis Macrocephalae 15g, Fructus Amomi Rotundus 12g, Radix Curcumae 15g, Saussurea lappa Clarke 15g, seed of Job's tears 50g, Semen Armeniacae Amarum 20g, Radix Platycodonis 15g, Radix Paeoniae Rubra 20g, Radix Sophorae Flavescentis 30g, Radix Isatidis 30g, Rhizoma Coptidis 15g, 450 of LIANBENSHUANGZHI DIWAN (1.5 milligrams every).
Its preparation method is:
With above-mentioned each medicine blanking impurity and silt particle, mix post-treatment simultaneously and become 150 order fine powders (generally not sieving), make tablet behind the sterilization.
The present composition can also be prepared into water pill, honeyed pill or concentrated oral liquid.Preparation method is conventional preparation method.

Claims (4)

1, a kind of pharmaceutical composition for the treatment of hepatitis is characterized in that preparing the raw material that its active component raw material comprises following weight portion:
Herba Artemisiae Scopariae 50--70, Radix Astragali 20--40, Pericarpium Citri Reticulatae Viride 10--30, Herba Scutellariae Barbatae 20--40, Herb Gynostemmae Pentaphylli 20--40, Rhizoma Atractylodis Macrocephalae 10--20, Fructus Amomi Rotundus 7--17, Radix Curcumae 10--20, Saussurea lappa Clarke 10--20, seed of Job's tears 40--60, Semen Armeniacae Amarum 10--30, Radix Platycodonis 10--20, Radix Paeoniae Rubra 10--30, Radix Sophorae Flavescentis 20--40, Radix Isatidis 20--40, Rhizoma Coptidis 10--20, LIANBENSHUANGZHI DIWAN 400--500 grain.
2, the pharmaceutical composition of treatment hepatitis according to claim 1, the dosage form that it is characterized in that compositions are any peroral dosage forms.
3, the pharmaceutical composition of treatment hepatitis according to claim 2, the dosage form that it is characterized in that compositions are capsule, water pill, honeyed pill, oral liquid, tablet or granule.
4, the preparation of drug combination method of the described treatment hepatitis of claim 1 is characterized in that each medicine is according to claim 1 mixed post-treatment simultaneously becomes fine powder, makes capsule, water pill, honeyed pill, oral liquid, tablet or granule.
CNA2008101477116A 2008-11-28 2008-11-28 Medicinal composition for treating hepatitis and preparation method thereof Pending CN101411847A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770188A (en) * 2016-05-10 2016-07-20 李艳凤 Traditional Chinese medicinal preparation for protecting liver and preparation method of traditional Chinese medicinal preparation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770188A (en) * 2016-05-10 2016-07-20 李艳凤 Traditional Chinese medicinal preparation for protecting liver and preparation method of traditional Chinese medicinal preparation
CN105770188B (en) * 2016-05-10 2019-12-06 李艳凤 liver-protecting traditional Chinese medicine preparation and preparation method thereof

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